Brichard, Laurent published the artcileAn Efficient Method for Enhancing the Reactivity and Flexibility of [18F]Fluoride Towards Nucleophilic Substitution Using Tetraethylammonium Bicarbonate, Recommanded Product: Tetraethylammonium hydrogencarbonate, the publication is European Journal of Organic Chemistry (2014), 2014(28), 6145-6149, database is CAplus.
The standard method used to generate reactive [18F]fluoride for [18F]radiolabelling is to trap it on an anion-exchange cartridge then elute it with a basic aqueous solution, which is then subjected to azeotropic evaporation to remove water. A method using tetraethylammonium hydrogen carbonate in which efficient recovery of [18F]fluoride (up to 99 %), remove the requirement for the time-consuming and inefficient azeotropic evaporation process and produce a reactive [18F]fluoride that can undergo a wide range of aliphatic and aromatic [18F]nucleophilic substitutions in up to 93 % radiochem. conversion at end-of-synthesis in the presence or without water is developed.
European Journal of Organic Chemistry published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C9H21NO3, Recommanded Product: Tetraethylammonium hydrogencarbonate.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia