Category: 1798-04-5

Bark, L. S. published the artcileThe effect of substituent groupings on the chromatographic behavior of phenoxyacetic acids. III. The effect of the nature of the substituent, COA of Formula: C12H16O3, the publication is Analyst (1960), 907-8, database is CAplus.

Para substituted phenoxyacetic acids were studied. The results indicate that the greater the probability of H bonding between the substituent and the stationary phase, the greater is the adsorption of the acid and hence the lower the R_f.

Analyst published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, COA of Formula: C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bark, L. S. published the artcileThe effect of substituent groupings on the chromatographic behavior of phenoxyacetic acids. II. Chloro-substituted phenoxyacetic acids, Related Products of catalysis-chemistry, the publication is Analyst (1960), 905-7, database is CAplus.

Twelve chloro-substituted phenoxyacetic acids (2-, 3-, and 4-chloro, 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5-dichloro, 2,4,5- and 2,4,6-trichloro) were studied. The acid can be adsorbed on paper by attachment of both the acid group and the substituent group to the cellulose, the substituent being attached by H bonding between the OH groups of the cellulose and the electroneg. atom of the substituent. The relatively low adsorption of acids substituted in both the 2 and 6 positions is probably caused by restriction of rotation of the phenoxyacetic acid grouping, resulting in attachment by this group only.

Analyst published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lee, Kyeong published the artcileDiscovery of a novel series of benzimidazole derivatives as diacylglycerol acyltransferase inhibitors, SDS of cas: 1798-04-5, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(24), 7456-7460, database is CAplus and MEDLINE.

A novel series of benzimidazole derivatives was prepared and evaluated for their diacylglycerol acyltransferase (DGAT) inhibitory activity using microsome from rat liver. Among the newly synthesized compounds, a furfurylamine containing benzimidazole carboxamide showed the most potent DGAT inhibitory effect (IC₅₀= 4.4 ¦ÌM) and inhibited triglyceride formation in HepG2 cells.

Bioorganic & Medicinal Chemistry Letters published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, SDS of cas: 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Xiong published the artcileThe influence of isomerism on the self-assembly behavior and complexation property of 1,3-alternate tetraaminopyridyl-thiacalix[4]arene derivatives, Synthetic Route of 1798-04-5, the publication is Tetrahedron (2008), 64(27), 6230-6237, database is CAplus.

A series of 1,3-alternate conformation thiacalix[4]arenes containing different isomeric aminopyridyl pendent arms have been synthesized. It was found that their self-assembly behaviors and complexation properties strongly depended on the structures of aminopyridyl pendent arms. The crystal structures demonstrate that tetra(meta-aminopyridyl)-thiacalix[4]arene motif is capable of forming intramol. hydrogen bondings between the sp² nitrogen donors in the meta position of the aminopyridyl groups and the facing amide N-H of the adjacent aminopyridyl groups, and self-assembles via C-H¡¤¡¤¡¤O weak hydrogen bondings and C-H¡¤¡¤¡¤¦Ð interaction to generate a double stranded rectilineal networks. By contrast, in the case of tetra(para-aminopyridyl)-thiacalix[4]arene, the presence of para-aminopyridyl units enables the formation of N-H¡¤¡¤¡¤N strong hydrogen bondings between the individual mols. leading to the solid-state structure with water-bridged double strands. Their complexation properties had been also studied by measurement of the stability constants for their complexation in a range of metal cations and investigation of their binding models via ¹H NMR titration and ESI-MS experiments It was found that the three ligands exhibited high and selective extractability toward Ag⁺, and their stoichiometry of ligand to Ag⁺ was 1:1, while the meta-aminopyridyl derivative showed the best extraction capacity and possessed the most efficient binding sites.

Tetrahedron published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Synthetic Route of 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Davidkova, P. published the artcileTLC and HPTLC of alkyl-substituted phenoxyalkanoic acids, Recommanded Product: 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Symposia Biologica Hungarica (1986), 567-78, database is CAplus.

The optimum conditions for the separation of alkyl-substituted phenoxyalkanoic acids by normal-phase partition and reversed-phase TLC and reversed-phase high-performance (HP) TLC on chem.-bonded phase were studied. The separated spots were detected by spraying with a 0.2% EtOH solution of 2,7-dichlorofluorescein.

Symposia Biologica Hungarica published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Recommanded Product: 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Davidkova, P. published the artcileSeparation efficiency of adsorption and partition thin-layer chromatography and reversed-phase high-performance thin-layer chromatography with chemically bonded phases for alkylphenoxyalkanoic acids, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Journal of Chromatography (1987), 410(1), 53-76, database is CAplus.

The separation of 32 alkyl-substituted phenoxyalkanoic acids from phenoxyacetic to 3-pentadecylphenoxylauric acid was studied using adsorption chromatog., 3 types of partition chromatog. (water, formamide, or liquid paraffin as stationary phases), and reversed-phase high-performance thin-layer chromatog. (RP-HPTLC) with chem. bonded phases. All these chromatog. systems were found suitable from the anal. point of view, but some differences in their suitability for the separation of lower or higher homologs or in their detection sensitivity were observed The most efficient methods seem to be RP-HPTLC and TLC on silica gel layers impregnated with formamide or DMF, resp., the former owing to the good separation of the highest lipophilic homologs and to the formation of discrete spots, permitting sharper anal. differentiation of acids with smaller R_f differences in general, and the latter owing to the highest ¦¤R_M values for the methylene groups of all the homologs in connection with high detection sensitivity. The best detection was achieved by using 2,7-dichlorofluorescein as the spray reagent followed by observation in UV light. The detection limit was 0.5-10 ¦Ìg of the acids, depending on the chromatog. system used.

Journal of Chromatography published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Manley, David W. published the artcileCatalyst-Free Photoredox Addition-Cyclisations: Exploitation of Natural Synergy between Aryl Acetic Acids and Maleimide, Category: catalysis-chemistry, the publication is Chemistry – A European Journal (2014), 20(18), 5492-5500, database is CAplus and MEDLINE.

Suitably functionalized carboxylic acids undergo a previously unknown photoredox reaction when irradiated with UVA in the presence of maleimide. Maleimide was found to synergistically act as a radical generating photoxidant and as a radical acceptor, negating the need for an extrinsic photoredox catalyst. Modest to excellent yields of the product chromenopyrroledione, thiochromenopyrroledione and pyrroloquinolinedione derivatives were obtained in thirteen preparative photolyses. In situ NMR spectroscopy was used to study each reaction. Reactant decay and product build-up were monitored, enabling reaction profiles to be plotted. A plausible mechanism, whereby photo-excited maleimide acts as an oxidant to generate a radical ion pair, has been postulated and is supported by UV/Vis. spectroscopy and DFT computations. The radical-cation reactive intermediates were also characterized in solution by EPR spectroscopy.

Chemistry – A European Journal published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Manley, David W. published the artcileTitania-Promoted Carboxylic Acid Alkylations of Alkenes and Cascade Addition-Cyclizations, Quality Control of 1798-04-5, the publication is Journal of Organic Chemistry (2014), 79(3), 1386-1398, database is CAplus and MEDLINE.

Photochem. reactions employing TiO₂ and carboxylic acids under dry anaerobic conditions led to several types of C-C bond-forming processes with electron-deficient alkenes. The efficiency of alkylation varied appreciably with substituents in the carboxylic acids. The reactions of aryloxyacetic acids with maleimides resulted in a cascade process in which a pyrrolochromene derivative accompanied the alkylated succinimide. The selectivity for one or other of these products could be tuned to some extent by employing the photoredox catalyst under different conditions. Aryloxyacetic acids adapted for intramol. ring closures by inclusion of 2-alkenyl, 2-aryl, or 2-oximinyl functionality reacted rather poorly. Profiles of reactant consumption and product formation for these systems were obtained by an in situ NMR monitoring technique. An array of different catalyst forms were tested for efficiency and ease of use. The proposed mechanism, involving hole capture at the TiO₂ surface by the carboxylates followed by CO₂ loss, was supported by EPR spectroscopic evidence of the intermediates. Deuterium labeling indicated that the titania likely donates protons from surface hydroxyl groups as well as supplying electrons and holes, thus acting as both a catalyst and a reaction partner.

Journal of Organic Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Quality Control of 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shimizu, Kazuki published the artcileBoron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1¦Á inhibitors, HPLC of Formula: 1798-04-5, the publication is Bioorganic & Medicinal Chemistry Letters (2010), 20(4), 1453-1456, database is CAplus and MEDLINE.

A series of boron-containing phenoxyacetanilide derivatives I [R¹ = BPin, B(OH)₂; R² = Me, Et, Ph, Cy, 1-adamantyl, t-Bu, o-carboranyl] were synthesized as hypoxia-inducible factor (HIF)-1¦Á inhibitors. Among the compounds synthesized, carboranylphenoxyacetanilide I [R¹ = B(OH)₂; R² = o-carboranyl (II)] was found to be a potent inhibitor against HIF-1¦Á accumulation under hypoxic conditions and inhibited the hypoxia-induced HIF-1 transcriptional activity in HeLa cells (IC₅₀ = 0.74 ¦ÌM). Compound II (GN26361) suppressed hypoxia-induced HIF-1¦Á accumulation and vascular endothelial growth factor mRNA expression in a concentration-dependent manner without affecting the expression of HIF-1¦Á mRNA.

Bioorganic & Medicinal Chemistry Letters published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C5H5BO4S, HPLC of Formula: 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rueda-Becerril, Montserrat published the artcileDirect C-F Bond Formation Using Photoredox Catalysis, Safety of 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Journal of the American Chemical Society (2014), 136(6), 2637-2641, database is CAplus and MEDLINE.

We have developed the first example of a photoredox catalytic method for the formation of carbon-fluorine (C-F) bonds. The mechanism has been studied using transient absorption spectroscopy and involves a key single-electron transfer from the ³MLCT (triplet metal-to-ligand charge transfer) state of Ru(bpy)₃²⁺ to Selectfluor. Not only does this represent a new reaction for photoredox catalysis, but the mild reaction conditions and use of visible light also make it a practical improvement over previously developed UV-mediated decarboxylative fluorinations.

Journal of the American Chemical Society published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Safety of 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia