Category: 1821-27-8

Winkelmann, E. published the artcileChemotherapeutically active nitro compounds. Part 2: nitrodiphenyl sulfones, Recommanded Product: Bis(4-nitrophenyl)amine, the publication is Arzneimittel-Forschung (1976), 26(8), 1543-7, database is CAplus and MEDLINE.

The 58 4-nitro-4′-aminodiphenyl sulfones and related compounds tested had a spectrum of tuberculostatic and antimalarial activity similar to that of 4,4′-diaminodiphenyl sulfone (DDS) [80-08-0], but offered no significant advantages over DDS. The tested compounds were presumably reduced to DDS derivatives in vivo. For example, 4-nitro-4′-formamidodiphenyl sulfone (I) [6784-23-2] at 150 mg/kg orally was highly effective against Mycobacterium bovis and Plasmodium berghii infections in mice.

Arzneimittel-Forschung published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C14H10O4, Recommanded Product: Bis(4-nitrophenyl)amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

North, Michael published the artcileDiastereoselective darzens condensations of ¦Á-haloamides: influence of aryl substituents on diastereoselectivity, Related Products of catalysis-chemistry, the publication is Letters in Organic Chemistry (2009), 6(7), 552-556, database is CAplus.

N,N-Diaryl ¦Á-haloamides undergo Darzens condensations with aldehydes induced by metal hydroxides. The diastereoselectivity of epoxide formation is strongly influenced by the electronic properties of the arylamide, which can be rationalized on the basis of the acidity of the substrate hydrogens and hence on reaction occurring under kinetic or thermodn. control.

Letters in Organic Chemistry published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Poyet, J. M. published the artcileAnalysis of stabilizers, plasticizers and impurities in explosives by liquid chromatography, SDS of cas: 1821-27-8, the publication is Symposium on Chemical Problems Connected with the Stability of Explosives, [Proceedings] (1977), 109-20, database is CAplus.

High-pressure liquid chromatog. (HPLC) has been used to determine nitroso and nitro derivatives of diphenylamine [122-39-4] and 2-nitrodiphenylamine [119-75-5] stabilizers in nitrocellulose [9004-70-0] and poly(vinyl nitrate) [26355-31-7] explosive powders. In the determination of diphenylamine derivatives, Microporasil was used as column packing and cyclohexane-1,2-dichloroethqne mixture as eluant. 2-Nitrodiphenylamine derivatives were estimated by inverse phase chromatog. on a Microbondapak C-18 1/4 column with MeOH-H2O (67.5:32.5) as eluant and (PhO)3PO as internal standard Trace amounts (0.01%) of RDX [121-82-4] in HMX [2691-41-0] also could be estimated on the Microporasil column with cyclohexane-dioxane-MeCN (63:34:3) as eluant.

Symposium on Chemical Problems Connected with the Stability of Explosives, [Proceedings] published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, SDS of cas: 1821-27-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Keshavarz, Mohammad Hossein published the artcileSimple Method for Prediction of the Standard Gibbs Free Energy of Formation of Energetic Compounds, Application In Synthesis of 1821-27-8, the publication is Propellants, Explosives, Pyrotechnics (2014), 39(6), 815-818, database is CAplus.

A reliable simple method for prediction of the standard Gibbs energy of formation (¦¤_fG^¦È) of energetic compounds containing nitroarom., acyclic, and cyclic nitramine, nitrate ester, and nitroaliph. compounds is introduced herein. The method is based on the contribution of elemental composition (¦¤_fG_elem^¦È) and the correcting function for the presence of additive and non-additive mol. fragments (¦¤_fG_corr^¦È). In presence of some mol. moieties, ¦¤_fG_corr^¦È may increase or decrease the value of ¦¤_fG_elem^¦È, depending on the intermol. interactions. The exptl. root-mean-square error (RMSE) of the novel correlation (22.7 kJ mol^-1) is quite good. For some energetic compounds, where the computed values of two complex models of the quant. structure-property relationship (QSPR) theory were available, the exptl. RMSE developed by the new method is smaller than the values obtained by QSPR method.

Propellants, Explosives, Pyrotechnics published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Application In Synthesis of 1821-27-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Jie published the artcileDesign, synthesis and antitumor activity of novel cis-furoquinoline derivatives, Recommanded Product: Bis(4-nitrophenyl)amine, the publication is Letters in Drug Design & Discovery (2012), 9(4), 379-388, database is CAplus.

A series of novel cis-furoquinoline derivatives, e. g. I, was synthesized and tested for antitumor activities in vitro against HepG2 cells, Lu-04 cells and Leu02 cells to evaluate structure-activity relationships. Assay-based antiproliferative activity study revealed that several compounds had significant cytotoxicity, among which 3 compounds were the most active and deserved further study as potential anticancer agents.

Letters in Drug Design & Discovery published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Recommanded Product: Bis(4-nitrophenyl)amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jacquemin, Denis published the artcileTD-DFT performance for the visible absorption spectra of organic dyes: Conventional versus long-range hybrids, Synthetic Route of 1821-27-8, the publication is Journal of Chemical Theory and Computation (2008), 4(1), 123-135, database is CAplus and MEDLINE.

The ¦Ð ¡ú ¦Ð* transitions of more than 100 organic dyes from the major classes of chromophores (quinones, diazo, …) have been investigated using a time-dependent d. functional theory procedure relying on large at. basis sets and the systematic modeling of solvent effects. These calculations have been performed with pure (PBE) as well as conventional (PBE0) and long-range (LR) corrected hybrid functionals (LC-PBE, LC-¦ØPBE, and CAM-B3LYP). The computed wavelengths are systematically guided by the percentage of exact exchange included at intermediate interelectronic distance, i.e., the ¦Ë_max value always follows the PBE > PBE0 > CAM-B3LYP > LC-PBE > LC-¦ØPBE > HF sequence. The functional giving the best estimates of the exptl. transition energies may vary, but PBE0 and CAM-B3LYP tend to outperform all other approaches. The latter functional is shown to be especially adequate to treat mols. with delocalized excited states. The mean absolute error provided by PBE0 is 22 nm (0.14 eV) with no deviation exceeding 100 nm (0.50 eV): PBE0 is able to deliver reasonable estimates of the color of most organic dyes of practical or industrial interest. By using a calibration curve, we found that the LR functionals systematically allow an even more consistent description of the low-lying excited-state energies than the conventional hybrids. Indeed, linearly corrected LR approaches yield an average error of 10 nm for each dye family. Therefore, when such statistical treatments can be designed for given sets of dyes, a simple and rapid theor. procedure allows both a chem. sound and a numerically accurate description of the absorption wavelengths.

Journal of Chemical Theory and Computation published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Synthetic Route of 1821-27-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Asquith, Raymond S. published the artcileThe fading of nitrodiphenylamine disperse dyes in relation to their structure and ultraviolet absorption spectra, Recommanded Product: Bis(4-nitrophenyl)amine, the publication is Journal of the Society of Dyers and Colourists (1968), 84(10), 507-10, database is CAplus.

A series of dinitrodiphenylamines was prepared by heating the appropriate BrC6H4NO2 with the O2NC6H4NHAc for 16 hrs. at 180¡ãC. in the presence of anhydrous K2CO3 and CuBr. The absorption spectra in the range 200-560 nm. were recorded for all of the purified dyes (25 ¡Á 10-6M) in absolute alc. All showed maximum in the 370-430 nm. region. Each dye was ground in a ball mill for 24 hrs. with H2O and a 10% solution of Dispersol VL. A 1% dyeing on secondary cellulose acetate was prepared Samples of the dyed material were exposed in a Xenotest 450 fading lamp at 30¡ã and 45% relative humidity. Exposure was continued until Blue Standard 7 had just started to fade (about 102 hrs.). All dyes darkened in color, turned brown, and then faded to a lighter color.

Journal of the Society of Dyers and Colourists published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Recommanded Product: Bis(4-nitrophenyl)amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bagheri, Sepideh published the artcileCopper(I)-creatine complex on magnetic nanoparticles as a green catalyst for N- and O-arylation in deep eutectic solvent, Safety of Bis(4-nitrophenyl)amine, the publication is Applied Organometallic Chemistry (2020), 34(3), e5447, database is CAplus.

Immobilization of copper(I) ions on magnetic nanoparticles was performed using surface modification of Fe₃O₄ with creatine. Fe_3O4@creatine-Cu(I) magnetic catalyst was synthesized and applied in C-X cross-coupling reactions with aryl halides in a deep eutectic as a green solvent. The results indicate that the Fe3O4@creatine-Cu(I) magnetic nanoparticles showed excellent activity and high stability. In addition, it was revealed that this catalyst can be recycled five times without significant loss in catalytic activity.

Applied Organometallic Chemistry published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Safety of Bis(4-nitrophenyl)amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kornev, K. A. published the artcileN-methyldiphenylamine 4,4-diisocyanate, Application of Bis(4-nitrophenyl)amine, the publication is Ukrainskii Khimicheskii Zhurnal (Russian Edition) (1968), 34(10), 1046-8, database is CAplus.

A mixture of 20.75 g. p-O2NC6H4-NH2, 15.2 g. K2CO3, and 7.8 g. o-HOC6H4COCl, was heated to 200¡ã during 1 hr. and held there for 30 min. before adding 23.6 g. p-ClC6H4NO2. Heating was continued for 12 hrs. forming p-(O2NC6H4)2NH (I), m. 211-12¡ã. I and MeI reacted in Me2CO containing KOH to form (p-O2NC6H4)2NMe, m. 179-80¡ã, reduced to (p-H2NC6H4)2NMe (II), m. 173-4¡ã, with N2H4 and Raney Ni in MeOH. A stream of HCl was passed through a boiling solution of II in PhMe to precipitate the salt. This was cooled and a solution of COCl2 in PhMe was added. COCl2 was passed slowly through the resultant mixture while it was refluxed on an oil bath. The excess COCl2 was removed with a stream of N. On cooling (p-OC-NC6H4)2NMe, m. 59-60¡ã, precipitated This with NH3 and PhNH2 formed MeN(C6H4NHCONH2-p)2, m. 219-21¡ã, and MeN(C6-H4NHCONHPh-p)2, m. 245-7¡ã, resp.

Ukrainskii Khimicheskii Zhurnal (Russian Edition) published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Application of Bis(4-nitrophenyl)amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Mori, Nobuo published the artcileIntramolecular hydrogen bonds. V. Aliphatic hydroxy carboxylates, Name: Bis(4-nitrophenyl)amine, the publication is Bulletin of the Chemical Society of Japan (1965), 38(12), 2149-55, database is CAplus.

cf. CA 63, 17169d. The ir spectra of a number of hydroxy carboxylates in CCl₄ were measured and the bands were explained on the basis of the possible rotational isomers around the C¦Á-O axis, as shown in I, II, IIIa, and IIIb and their mirror images. The aliphatic esters studied are of the type R¹R²C(OH)(CH₂)_n-1CO₂R (IV) (n, R¹, R², and R given): 1, H, H, Et (IVa); 1, Me, H, Me (IVb) (b₄₆ 68¡ã); 1, Me, H, Et (IVc); 1, Me, H, iso-Pr (IVd) (b₄₀ 74¡ã); 1, Me, Me, Et (IVe); 2, H, H, Me (IVf) (b₁₅ 74¡ã); 2, H, H, Et (IVg); 2, Me, H, Me (IVh) (b₁₃ 67¡ã); 2, Me, H, Et (IVi); 2, Me, Me, Me (IVj) (b₁₅ 67¡ã); 3, Me, H, Et (IVk) (b₂ 85-7¡ã); 5, H, H, Et (IVl) (b₂₀ 138¡ã); 6, H, H, Et (b₁₅ 145¡ã); 8, H, H, Et (b₂ 131-2¡ã); 9, H, H, Et; 10, H, H, Et. The following cyclic esters (V) were studied (R and position of OH given): Me, 1 (Va) (b₁₀ 87¡ã, n²⁵_D 1.4585); Me, cis-2 (b₁₄ 103¡ã, n²⁵_D 1.4637); Et, cis-2; Me, trans-2 (b₁₄ 112.5¡ã, n²⁵_D 1.4634); Et, trans-2; Me, cis-3 (Vb) (b₅ 113-15¡ã, n²⁵_D 1.4658); Me, trans-3 (b₆ 111-12¡ã n²⁵_D 1.4657); Me, cis-4 (Vc) (b₁₂ 128¡ã, n²⁵_D 1.4684); Me, trans-4 (b₁₂ 125¡ã, n²⁵_D 1.4669). The ¦Á-OH esters IVa-e and Va showed a strong band due to H bonding with carbonyl oxygen (form I) and a weak one due to H bond with ether oxygen (form II). The frequency of the latter band decreased with increasing number of Me groups attached to the ¦Á-carbon atom. The ratio of the absorbance of the weak band to that of the strong band (Dw/Ds) was substantially constant in ¦Á-esters, but decreased as the alc. alkyl portion of the ester group increased in bulk or in the number of C atoms. The relatively high ratio for Va was explained in terms of possible steric repulsion between the axial H on C-2 and C-6 and the alkoxy group. Of the ¦Â-OH esters studied, IVf and IVg showed bands corresponding to forms I, IIIa and IIIb, while IVh-j showed bands corresponding to forms I, II and a mixture of IIIa and IIIb. The Me group on the ¦Â-carbon atom sterically serve to make the OH and the ester group closer together; the non-bonded forms IIIa and IIIb decrease in proportion, and the form II comes into existence. IVk and IV1 showed 3 bands corresponding to forms I, IIIa, and a mixture of IIIa and IIIb. Higher ¦Ø-hydroxy esters formed no H-bonding. The absence of H-bonding in Vc was due to the instabilization resulting from assuming the boat or twist conformation. The orientation of the ester group in its 1,3-diaxial chair conformation is unfavorable for H-bonding in Vb. Comparison of the H-bonding frequencies of the hydroxy esters with ¦Á,¦Ø-alkanediols and ¦Ø-methoxy alkanols of the series RO(CH₂)_nOH, where R = Me or H, indicated, the frequency corresponding to form I in esters was much lower, but for form II, it was higher than those of the other series, when the number of members in a ring to be formed through H bonding was equal to 5. When the ring consists of six members or more, the frequencies for forms I and II of the esters were higher than those of both the alkanol series.

Bulletin of the Chemical Society of Japan published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Name: Bis(4-nitrophenyl)amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia