Category: 22693-41-0

Tang, Kaluo published the artcileStudies of trinuclear cadmium cluster complexes. Syntheses and crystal structures of [NMe₄][Cd₃(SC₆H₂Prⁱ₃-2,4,6)₇].C₅H₁₂ and [Cd₃(SC₆H₂Prⁱ₃-2,4,6)₆(HSC₆H₂Prⁱ₃-2,4,6)].CH₃OH.7H₂O, Application of 2,4,6-Triisopropylbenzenethiol, the publication is Journal of Coordination Chemistry (1994), 31(4), 305-20, database is CAplus.

By the reaction of a sterically hindered arenethiol, 2,4,6-(Me₂CH)₃C₆H₂SH (HL), with Cd(NO₃)₂.4H₂O under different conditions, the colorless salt of trinuclear cadmium cluster anion complex [NMe₄][Cd₃(L)₇].C₅H₁₂ (I) and the uncharged trinuclear cadmium complex [Cd₃(L)₆(HL)].MeOH.7H₂O (II) were synthesized and structurally characterized. Crystals of I are monoclinic, space group P2₁/n with a 19.629(6), b 25.608(9), c 25.450(9) ?, ¦Â 107.54(3)¡ã, Z = 4, R = 0.076 for 3839 observed reflections. Crystals of II are triclinic, space group, P1? with a 19.792(10), b 20.508(12), c 33.97(2) ?, ¦Á 85.81(5), ¦Â 86.77(5), ¦Ã 85.12(4)¡ã, Z = 4, R = 0.0921 for 8327 observed reflections. The core of the cluster anion of I is formed by a defect cubane unit with 3 cadmium and 4 sulfur atoms at its vertexes. Each cadmium atom exhibits tetrahedral coordination with 1 terminal sulfur, 2 doubly bridging sulfur and 1 triply bridging sulfur atoms. In complex II, 3 cadmium atoms are coordinated by 6 thiolate (RS^–) and 1 thiol (RSH) ligands. Two of 3 cadmium atoms have tetrahedral coordination and 1 is trigonal planar.

Journal of Coordination Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C28H29NO4, Application of 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Che, Chao published the artcileTricyclic Aza-Andrographolide Derivatives from Late-Stage Hydroamination and Their Anti-human Coronavirus (Anti-HCoV) Activity, Recommanded Product: 2,4,6-Triisopropylbenzenethiol, the publication is ACS Omega (2022), 7(28), 24824-24837, database is CAplus and MEDLINE.

A late-stage functionalization (LSF) of the natural product andrographolide for the efficient assembly of a range of structurally interesting and diverse tricyclic-aza derivatives was developed. The key to the diversification is a photo-catalyzed intramol. hydroamination reaction, and acridinium derivatives were demonstrated to be the optimal catalysts. Addnl., the synthesized tricyclic aza-andrographolide derivatives were found to inhibit human coronavirus with high potency.

ACS Omega published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Recommanded Product: 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nakamura, Shuichi published the artcileEnantioselective Reaction of ¦Á-Lithiated Dithioacetals Using Chiral Bis(oxazoline)s: New Chiral Formyl Anion Equivalents, Recommanded Product: 2,4,6-Triisopropylbenzenethiol, the publication is Journal of Organic Chemistry (2004), 69(5), 1581-1589, database is CAplus and MEDLINE.

The enantioselective reaction of various ¦Á-lithiated dithioacetals with aldehydes or a ketone in the presence of bis(oxazoline)s was examined Among them, unsym. dithioacetals were found to be the best choice for attaining high enantioselectivity. The reaction of lithiated tert-butylthio(2-pyridylthio)methane with aldehydes proceeded with good diastereoselectivity as well as with good enantioselectivity. The enantioselective reaction was shown to proceed through dynamic thermodn. resolution Mercury(II) chloride effected hydrolysis of the dithioacetal moiety of the products to 2-hydroxyaldehydes, which were directly reduced to give the optically active 1,2-diols.

Journal of Organic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Recommanded Product: 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Olaizola, Olatz published the artcileBronsted Base Catalyzed One-Pot Synthesis of Stereodefined Six-Member Carbocycles Featuring Transient Trienolates and a Key Intramolecular 1,6-Addition, Name: 2,4,6-Triisopropylbenzenethiol, the publication is Angewandte Chemie, International Edition (2019), 58(40), 14250-14254, database is CAplus and MEDLINE.

A catalyst-driven one-pot reaction sequence is developed for the enantio- and diastereoselective synthesis of tetrasubstituted cyclohexenes from simple unsaturated ketones or thioesters. The method involves a tertiary amine/squaramide-catalyzed ¦Á-selective addition of transiently generated trienolates to nitroolefins, subsequent base-catalyzed double bond isomerization, and an intramol. (vinylogous) 1,6-addition reaction, a rare key carbocyclization step that proceeded with essentially perfect stereocontrol.

Angewandte Chemie, International Edition published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Name: 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ohki, Yasuhiro published the artcileSynthesis, Structures, and Electronic Properties of [8Fe-7S] Cluster Complexes Modeling the Nitrogenase P-Cluster, Safety of 2,4,6-Triisopropylbenzenethiol, the publication is Journal of the American Chemical Society (2009), 131(36), 13168-13178, database is CAplus and MEDLINE.

High-yield synthesis of the Fe-S cluster [{N(SiMe₃)₂}{SC(NMe₂)₂}Fe₄S₃]₂(¦Ì₆-S) {¦Ì-N(SiMe₃)₂}₂ (1), which reproduces the [8Fe-7S] core structure of the nitrogenase P^N-cluster, was achieved via two pathways: (1) Fe{N(SiMe₃)₂}₂ + HSTip (Tip = 2,4,6-ⁱPr₃C₆H₂) + tetramethylthiourea (SC(NMe₂)₂) + elemental S (S₈); and (2) Fe₃{N(SiMe₃)₂}₂(¦Ì-STip)₄ (2) + HSTip + SC(NMe₂)₂ + S₈. The thiourea and terminal amide ligands of 1 are replaceable by thiolate ligands upon treatment with thiolate anions and thiols at -40¡ã, resp., and [8Fe-7S] clusters bearing two to four thiolate ligands were synthesized and their structures were determined by x-ray anal. The structures of these model [8Fe-7S] clusters all closely resemble that of the reduced form of P-cluster (P^N) having 8Fe(II) centers, while their 6Fe(II)-2Fe(III) oxidation states correspond to the oxidized form of P-cluster (P^OX). The cyclic voltammograms of the [8Fe-7S] clusters reveal two quasi-reversible 1-electron reduction processes, leading to the 8Fe(II) state that is the same as the P^N-cluster, and the synthetic models demonstrate the redox behavior between the two major oxidation states of the native P-cluster. Replacement of the SC(NMe₂)₂ ligands in 1 with thiolate anions led to more neg. reduction potentials, while a slight pos. shift occurred upon replacement of the terminal amide ligands with thiolates. The clusters 1, (NEt₄)₂[{N(SiMe₃)₂}(SC₆H₄-4-Me)Fe₄S₃]₂(¦Ì₆-S){¦Ì-N(SiMe₃)₂}₂ (3a), and [(SBtp){SC(NMe₂)₂}Fe₄S₃]₂(¦Ì₆-S){¦Ì-N(SiMe₃)₂}₂ (5; Btp = 2,6-(SiMe₃)₂C₆H₃) are EPR silent at 4-100 K, and their temperature-dependent magnetic moments indicate a singlet ground state with antiferromagnetic couplings among the Fe centers. The ⁵⁷Fe Mossbauer spectra of these clusters are consistent with the 6Fe(II)-2Fe(III) oxidation state, each exhibiting two doublets with an intensity ratio of ?1:3, which are assignable to Fe(III) and Fe(II), resp. Comparison of the quadrupole splittings for 1, 3a, and 5 indicated that two Fe(III) sites of the clusters are the peripheral Fe atoms.

Journal of the American Chemical Society published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Safety of 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ohki, Yasuhiro published the artcileSynthesis of New [8Fe-7S] Clusters: A Topological Link between the Core Structures of P-Cluster, FeMo-co, and FeFe-co of Nitrogenases, Application of 2,4,6-Triisopropylbenzenethiol, the publication is Journal of the American Chemical Society (2007), 129(34), 10457-10465, database is CAplus and MEDLINE.

A coordinatively unsaturated dinuclear Fe(II) complex of bulky thiolates, [(TipS)Fe(¦Ì-SDmp)]₂ (1; Tip = 2,4,6-ⁱPr₃C₆H₂, Dmp = 2,6-(mesityl)₂C₆H₃), was synthesized from stepwise reactions of Fe{N(SiMe₃)₂}₂ with 1 equiv of HSDmp and then with 1 equiv of HSTip. Complex 1 was found to react with elemental S (S₈) in toluene to generate a new class of [8Fe-7S] cluster, [(DmpS)Fe₄S₃]₂(¦Ì-SDmp)₂(¦Ì-STip)(¦Ì₆-S) (2). The cluster 2 was also produced from 1-pot reactions of Fe{N(SiMe₃)₂}₂ + HSDmp + HSTip + S₈ (8p6:10:7/8) and Fe₃{N(SiMe₃)₂}₂(¦Ì-STip)₄ + HSDmp + S₈ (8/3:16/3:7/8), where another [8Fe-7S] cluster, [(TipS)Fe₄S₃]₂(¦Ì-SDmp)₂{¦Ì-N(SiMe₃)₂}(¦Ì₆-S) (3), was also found as a minor byproduct. In either of the clusters, two Fe₄S₃ incomplete cubane units are connected by three anionic ligands, three thiolate S atoms for 2 or two thiolate S atoms and one amide N atom for 3, and one hexacoordinate S atom resides at the center of the [8Fe-7S] core. They have a common Fe(II)₅Fe(III)₃ oxidation states, and an S = ¹/₂ ground spin state was indicated by rhombic EPR signals at 10 K with g = 2.19, 2.07, and 1.96 for 2 and g = 2.13, 2.06, and 1.93 for 3. The structural relevance of clusters 2 and 3 to P-cluster, FeMo-co, and FeFe-co of nitrogenases is discussed.

Journal of the American Chemical Society published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Application of 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dilworth, Jonathan R. published the artcileSyntheses and structures of [Re(SC₆H₃Me₂-2,6)₃(PPh₃)], [Re(SC₆H₃Me₂-2,6)₃(Bu^tNC)₂], [Re(SC₆H₂Prⁱ₃-2,4,6)₃L(PPh₃)] (L = N₂ or CO) and [ReH₄(PPh₃)₄][ReO(SC₆H₂Prⁱ₃-2,4,6)₄], Quality Control of 22693-41-0, the publication is Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1995), 3153-64, database is CAplus.

The hydride [ReH₇(PPh₃)₂] reacted with 2,6-dimethylbenzenethiol in toluene to give [Re(SC₆H₃Me₂-2,6)₃(PPh₃)] (1). A crystal structure showed a trigonal-bipyramidal geometry about the Re with an agostic interaction to a thiolate Me occupying an apical site, trans to the PPh₃ ligand. 1 Reacts rapidly with MeCN to give the known [Re(SC₆H₃Me₂-2,6)₃(MeCN)(PPh₃)] (2) and with Bu^tNC to form [Re(SC₆H₃Me₂-2,6)₃(Bu^tNC)₂] (3). The crystal structure of 3 showed trigonal-pyramidal geometry about the Re with asym. coordination of the isocyanide ligands and an unusual configuration for the thiolate aromatic groups. The reactions of the hydrides [ReH₇(PPh₃)₂] and [ReH₅(PPh₃)₃] with 2,4,6-triisopropyl-, 2,6-dimethoxybenzenethiol and tris(2-sulfanylphenyl)phosphine were also studied. With HSC₆H₂Prⁱ₃-2,4,6, [Re(SC₆H₂Prⁱ₃-2,4,6)₃(N₂)(PPh₃)] (4) was formed and its structure determined The preparations and structures of [ReH₄(PPh₃)₄][ReO(SC₆H₂Prⁱ₃-2,4,6)₄], [Re{SC₆H₃(OMe)₂-2,6}₃(PPh₃)] and [Re{P(C₆H₄S-2)₃}(PPh₃)] are also discussed. An alternative convenient route to [ReH₄(PPh₃)₄]⁺ from [ReH₅(PPh₃)₃] is presented.

Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Quality Control of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tucci, Gregory C. published the artcileNickel-Mediated Formation of Thio Esters from Bound Methyl, Thiols, and Carbon Monoxide: A Possible Reaction Pathway of Acetyl-Coenzyme A Synthase Activity in Nickel-Containing Carbon Monoxide Dehydrogenases, Computed Properties of 22693-41-0, the publication is Journal of the American Chemical Society (1995), 117(24), 6489-96, database is CAplus.

Current mechanistic proposals for the acetyl-CoA synthase activity of nickel-containing carbon monoxide dehydrogenases (CH₃-THF + CoA¡¤SH ¡ú CoA¡¤SCOCH₃ + THF; THF = tetrahydrofolate, CoA¡¤SH = CoA) implicate a Ni catalytic center and the steps [Ni-CH₃] ¡ú [Ni-COCH₃] ¡ú CoA¡¤SCOCH₃. The second step presumably involves attack by the sulfur nucleophile of CoA at the acyl carbon atom in the overall reaction [Ni^II-COCH₃] + RS(H) ¡ú RSCOCH₃ + Ni^II (+ H⁺) + 2e^–. We have previously demonstrated these steps in Ni(II) complexes with physiol.-type ligation. In this work, it is shown that the reaction of acyl and thiolate ligands coordinated to Ni(I) affords thio esters in high yield. The complex [Ni(bpy)(CH₃)₂], established to be planar by an x-ray structure determination, reacts with 1 equiv of arenethiol to afford diamagnetic planar [Ni(bpy)(CH₃)(SR)] (8) with R = p-C₆H₄CH₃ (8a), 2,6-C₆H₃(CH₃)₂ (8b), mesityl (8c), 2,4,6-C₆H₂iPr₃ (8d), and 2,6-C₆H₃Cl₂ (8e) (bpy = 2,2′-bipyridyl). An analogous reaction gives [Ni(bpy)(C₂H₅)(S-mesityl)] (12) from [Ni(bpy)(C₂H₅)₂]. Planar structures of 8c,e were confirmed by x-ray anal. Complexes 12 and 8 with different R substituents undergo thiolate ligand exchange in THF with K_e. Reaction of 8e with 1 equiv of carbon monoxide yields the acyl complex [Ni(bpy)(COCH₃)(S-2,6-C₆H₃Cl₂)] (9a), whose planar coordination unit was confirmed by x-ray methods. Treatment of the complexes 8 in THF with more than 3 equiv of carbon monoxide yields [Ni(bpy)(CO)₂] and the thio esters RSCOCH₃ in 96-100% yield in situ. A solution initially containing 8b and 12 gave under the same conditions four thio esters in equal amounts, consistent with four complexes in the equilibrated solution prior to reaction with carbon monoxide. Reaction of 9a in THF with carbon monoxide produced 2,6-dichlorophenyl thioacetate quant., indicating that Ni(II)-acyl-thiolate complexes are intermediates in thio ester formation. The overall reaction is [Ni(bpy)(R’)(SR)] + 3CO ¡ú RSCOR’ + [Ni(bpy)(CO)₂] (R’ = CH₃, C₂H₅); the two electrons in the generalized reaction are captured by the metal as Ni(0). A related and necessarily intramol. reaction of [Ni(bpy)(SCH₂CH₂CH₂)] was confirmed and shown to produce ¦Ã-thiobutyrolactone in quant. yield in situ. Evidence supporting an analogous intramol. path for reaction systems based on 8 is summarized. This investigation provides the first examples of Ni-mediated acyclic thio ester synthesis and demonstrates a possible means of enzymic thio ester formation should CoA^– and an acetyl group coordinate to the Ni(II) catalytic center.

Journal of the American Chemical Society published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C12H14BNO2, Computed Properties of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nakamoto, Masami published the artcilePreparation and crystal structures of gold(I) complexes of a series of benzenethiolates: pair formation by gold-to-gold interactions of (benzenethiolato)(triphenylphosphine)gold(I), Application In Synthesis of 22693-41-0, the publication is Chemische Berichte (1993), 126(3), 605-10, database is CAplus.

Ph₃PAuCl reacts readily with PhSH and sterically hindered 2,4,6-R₃C₆H₂SH in the presence of NEt₃ to yield stable Ph₃PAu(SC₆H₂R₃-2,4,6) (1–4; R = H, Me, Et, CHMe₂, resp.). The crystal structures of these complexes were determined by single-crystal x-ray diffraction anal. In all compounds the Au atoms are linearly 2-coordinate with very similar bond lengths and angles. While 2–4 with bulky thiolate ligands are monomeric in the crystal lattice, 1 forms pairs of mols. with intermol. Au-Au contacts of 313.5(5) pm. The Moessbauer spectra of the complexes exhibit large isomer shifts (I.S.), of 3.06¡ú3.72 mm s^-1, and quadrupole splittings (Q.S.), of 7.90¡ú8.68 mm s^-1. These data can be attributed to the strong electron-donating properties of the benzenethiolate ligands. The Au-Au contacts in 1 lead to I.S. and Q.S. values which are slightly smaller than those of 2–4. The Au-S distances do not show a major influence of the S-Au-P pairing in 1 as compared to 2–4.

Chemische Berichte published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Application In Synthesis of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Delgado, Esther published the artcileIron carbonyls with bulky thiolate ligands: crystal structures of [Fe₂(CO)₆(¦Ì-SC₆H₂ⁱPr₃-2,4,6)₂] and (C₆H₂ⁱPr₃-2,4,6)₂S₂, Computed Properties of 22693-41-0, the publication is Inorganica Chimica Acta (1999), 284(1), 14-19, database is CAplus.

The reaction of Fe₃(CO)₁₂ and bulky thiols HSR (R = C₆H₂ⁱPr₃-2,4,6; C₆H₂Me₃-2,4,6) in toluene yielded [Fe₂(CO)₆(¦Ì-SR)₂] (R = C₆H₂ⁱPr₃-2,4,6 (1), C₆H₂Me₃-2,4,6 (2)). The substitution of one carbonyl by the phosphine Ph₂P(CH₂)₂Si(OEt)₃ in complex 1 afforded {Fe₂(CO)₅[Ph₂P(CH₂)₂Si(OEt)₃](¦Ì-SC₆H₂ⁱPr₃-2,4,6)₂} (3). Mononuclear [(¦Ç⁵-C₅H₅)Fe(CO)₂(SC₆H₂ⁱPr₃-2,4,6)] (4) and {(¦Ç⁵-C₅H₅)Fe(CO)[Ph₂P(CH₂)₂Si(OEt)₃](SC₆H₂ⁱPr₃-2,4,6)} (5) also were obtained. Compound 1 was studied by x-ray diffraction and the structure determined reveals a distorted octahedron geometry around each iron atom and confirms the anti arrangement of aryl substituents in the mol. The preparation of thiol HSC₆H₂ⁱPr₃-2,4,6 yielded the disulfide (C₆H₂ⁱPr₃-2,4,6)₂S₂ (6) as a byproduct, whose structure was solved by x-ray diffraction. Crystal data: 1, monoclinic, space group P2₁/a; 6, orthorhombic, space group Pbca.

Inorganica Chimica Acta published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Computed Properties of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia