Category: 613-33-2

Zhang, Dejiang published the artcileNickel- and Palladium-Catalyzed Cross-Coupling of Stibines with Organic Halides: Site-Selective Sequential Reactions with Polyhalogenated Arenes, Computed Properties of 613-33-2, the publication is ACS Catalysis (2022), 12(2), 854-867, database is CAplus.

Herein, the authors disclose a general and efficient method for the synthesis of Sb-aryl and Sb-alkyl stibines by the Ni-catalyzed cross-coupling of halostibines with organic halides. The synthesized Sb-aryl stibines couple with aryl halides to give biaryls efficiently via Pd catalysis. Sequential reactions of stibines with polyhalogenated arenes bearing active C-I/C-Br sites and inactive C-Cl sites successfully proceeded, giving a variety of complex mols. with good site selectivity. Drugs such as diflunisal and fenbufen, as well as a fenofibrate derivative, were synthesized on gram scales in good yields, together with the high recovery of chlorostibine. Also, catalytic mechanisms are proposed based on the results of control experiments

ACS Catalysis published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C9H12O, Computed Properties of 613-33-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huang, Qiang published the artcileIron-Catalyzed Vinylzincation of Terminal Alkynes, Recommanded Product: 4,4′-Dimethyldiphenyl, the publication is Journal of the American Chemical Society (2022), 144(1), 515-526, database is CAplus and MEDLINE.

Organozinc reagents are among the most commonly used organometallic reagents in modern synthetic chem., and multifunctionalized organozinc reagents can be synthesized from structurally simple, readily available ones by alkyne carbozincation. However, this method suffers from poor tolerance for terminal alkynes, and transformation of the newly introduced organic groups is difficult, which limits its applications. Herein, the authors report a method for vinylzincation of terminal alkynes catalyzed by newly developed Fe catalysts bearing 1,10-phenanthroline-imine ligands. This method provides efficient access to novel organozinc reagents with a diverse array of structures and functional groups from readily available vinylzinc reagents and terminal alkynes. The method features excellent functional group tolerance (tolerated functional groups include amino, amide, cyano, ester, hydroxyl, sulfonyl, acetal, phosphono, pyridyl), a good substrate scope (suitable terminal alkynes include aryl, alkenyl, and alkyl acetylenes bearing various functional groups), and high chemoselectivity, regioselectivity, and stereoselectivity. The method could significantly improve the synthetic efficiency of various important bioactive mols., including vitamin A. Mechanistic studies indicate that the new Fe-1,10-phenanthroline-imine catalysts developed in this study has an extremely crowded reaction pocket, which promotes efficient transfer of the vinyl group to the alkynes, disfavors substitution reactions between the Zn reagent and the terminal C-H bond of the alkynes, and prevents the further reactions of the products. The authors’ findings show that Fe catalysts can be superior to other metal catalysts in terms of activity, chemoselectivity, regioselectivity, and stereoselectivity when suitable ligands were used.

Journal of the American Chemical Society published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, Recommanded Product: 4,4′-Dimethyldiphenyl.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kuzhalmozhi Madarasi, Packirisamy published the artcileGrignard reagent dictated copper(I) phosphines catalyzed reductive coupling of diazo compounds: The chemistry beyond carbene generation, Category: catalysis-chemistry, the publication is Applied Organometallic Chemistry (2022), 36(2), e6522, database is CAplus.

Copper-dppf catalyzed reductive coupling of diazo compounds through a terminal nitrogen is reported. However, copper catalysts are known to produce carbene from diazo compounds Reaction conditions play an important role in formation of diazine over carbene generation. Several control experiments were conducted to understand the reaction mechanism and the authors found that formation of a copper-Mg heterobimetallic complex is responsible for the observed reactivity pattern. The reaction produced diazine as a reductive coupling product along with biphenyl as a byproduct. All synthesized diazines were characterized fully by using anal. and spectroscopic techniques.

Applied Organometallic Chemistry published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sabarudin, Akhmad published the artcilePreparation of Metal-Immobilized Methacrylate-Based Monolithic Columns for Flow-Through Cross-Coupling Reactions, COA of Formula: C14H14, the publication is Molecules (2021), 26(23), 7346, database is CAplus and MEDLINE.

In this work, with the aim of developing efficient flow-through microreactors for high-throughput organic synthesis, microreactors were fabricated by chem. immobilizing palladium-, nickel-, iron-, and copper-based catalysts onto ligand-modified poly(glycidyl methacrylate-co-ethylene dimethacrylate) [poly(GMA-co-EDMA)] monoliths, which were prepared inside a silicosteel tubing (10 cm long with an inner diameter of 1.0 mm) and modified with several ligands including 5-amino-1,10-phenanthroline, iminodiacetic acid, and iminodi(methylenephosphonic) acid. The performance of the resulting microreactors in Suzuki-Miyaura cross-coupling reactions was evaluated, and it was found that the poly(GMA-co-EDMA) monolith chem. modified with 5-amino-1,10-phenanthroline as a binding site for the palladium catalyst provides an excellent flow-through performance, enabling highly efficient and rapid reactions with high product yields. Moreover, this monolithic microreactor maintained its good activity and efficiency during prolonged use.

Molecules published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, COA of Formula: C14H14.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xie, Xiaoyan published the artcileGC-MS analysis and antifungal activity of essential oils from aerial parts of Senecio laetus Edgew. of Yunnan Province, Recommanded Product: 4,4′-Dimethyldiphenyl, the publication is Zhonghua Zhongyiyao Xuekan (2021), 39(2), 98-101, database is CAplus.

Objective Senecio Laetus Edgew. is a kind of medicinal plant of Senecio L. in Compositae. It has the functions of promoting blood circulation, detumescence, dispelling wind and dehumidifying. The aim of this study was to evaluate the antifungal activity of Senecio L. and analyze the essential oils from Senecio L. in Yunnan province by GC-MS. Methods The volatile oil from the aerial part of Senecio L. was extracted by steam distillation and the in vitro anti-Candida albicans activity was evaluated. The chem. constituents of the volatile oil were qual. analyzed by gas chromatog.-mass spectrometry (GC-MS). Results It showed that the essential oils from Senecio L. could reverse resistance of fluconazole to Candida albicans significantly. Further GC-MS anal. of volatile oil obtained 74 compounds, accounting for 73.3% of the total distillation peak area. These compounds were mainly terpenoids, aromatic and aliphatic compounds Conclusion The aerial parts of Senecio L. from Yunnan Province were analyzed by GC-MS for the first time. A total of 74 chem. constituents of volatile oil were obtained. The results provided theor. and exptl. data for drugs with synergistic anti-fungal effect in combination with existing anti-fungal drugs. This study provided a scientific basis for further research on the medicinal value of Senecio L. in the future.

Zhonghua Zhongyiyao Xuekan published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C12H16O3, Recommanded Product: 4,4′-Dimethyldiphenyl.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shishilov, Oleg N. published the artcilePalladium Nitrosyl Complexes as Highly Versatile Catalysts for C-H/C-H Oxidative Coupling of Arenes: Application Area and Insight into Mechanism, Formula: C14H14, the publication is ChemistrySelect (2021), 6(8), 1795-1803, database is CAplus.

Palladium nitrosyl carboxylates Pd₃(NO)₂(CX₃CO₂)₄(ArH)₂ (X = Cl, Ar = Ph; X = F, Ar = Tol) were found to be effective catalysts for synthesis of biaryls Ar¹Ar² = [Ar¹ = 4-MeC₆H₄, 2-ClC₆H₄, 3-F₃CC₆H₄, etc.; Ar² = 2-MeC₆H₄, 2-ClC₆H₄, 3-F₃CC₆H₄, etc.] via C-H/C-H oxidative homocoupling of arenes bearing electron-donor as well as electron-withdrawing groups (EWG). Trifluoroacetate complex Pd₃(NO)₂(CX₃CO₂)₄(ArH)₂ (X=F, Ar=Tol) was found to be more promising due to higher stability under the reaction conditions. Trifluoroacetate complex also showed high performance in intramol. coupling in diarylsulfides, diarylethers and diarylamines gave corresponding dibenzothiophenes/dibenzofurans/carbazoles I [R¹ = H, Me; R² = H, Me, CF₃, etc.; Y = O, S, NH] with yields ranged from moderate to high. The plausible mechanism was studied by DFT computational anal. basing on Pd₃ linear complexes as major active species. It was found that two deprotonation steps proceeded in two different ways: for the first deprotonation S_EAr was most probable pathway while for the second one concerted metalation-deprotonation (CMD) was preferable. That could explain high tolerance of the system to different substrates: S_EAr was favorable in the presence of electron donor group and EWG facilitated CMD. NO group was found to be involved into the CMD pathway and that was the rate-determining step with the highest activation barrier.

ChemistrySelect published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C9H11BO4, Formula: C14H14.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Di Terlizzi, Lorenzo published the artcileVisible Light-Driven, Gold(I)-Catalyzed Preparation of Symmetrical (Hetero)biaryls by Homocoupling of Arylazo Sulfones, COA of Formula: C14H14, the publication is Journal of Organic Chemistry (2022), 87(7), 4863-4872, database is CAplus and MEDLINE.

The preparation of sym. (hetero)biaryls via arylazo sulfones was successfully carried out upon visible light irradiation in the presence of PPh₃AuCl as the catalyst. The present protocol led to the efficient synthesis of a wide range of target compounds in an organic-aqueous solvent under photocatalyst-free conditions.

Journal of Organic Chemistry published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, COA of Formula: C14H14.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bhowmik, Tanmay published the artcileHighly dispersed palladium nanoparticles supported on graphitic carbon nitride for selective hydrogenation of nitro compounds and Ullmann coupling reaction, Quality Control of 613-33-2, the publication is Applied Organometallic Chemistry (2022), 36(4), e6613, database is CAplus.

High catalytic activity and superior stability are important criterion for the utilization of a noble metal-based nano-composite catalyst. Herein, we report a facile synthesis of highly dispersed palladium nanoparticles embedded on graphitic carbon nitride (Pd@CN_x) by ultrasound assisted method without aid of any external reducing agent. The Pd@CN_x composite was well characterized by different techniques. This Pd@CN_x shows effective catalytic activity towards easy dehydrogenation of sodium borohydride (NaBH₄) and ammonia borane in aqueous medium and also can easily hydrogenate 4-nitrophenol to 4-aminophenol with fast kinetics. The catalyst is highly selective towards nitro groups in presence of other reducible groups with good stability. Furthermore, the catalyst exhibits superior catalytic activity towards Ullmann coupling reaction of different aryl halides with broad range of substrates scope with easy recovery of the catalyst and notable recycling property.

Applied Organometallic Chemistry published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, Quality Control of 613-33-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kalishomi, R. Ghavidel published the artcileHeterogeneous Fe₃O₄@Si-NHC-Pd Catalyst: Synthesis, Characterization, and Catalytic Activity in the Suzuki-Miyaura Cross-Coupling Reaction under Mild Conditions, Quality Control of 613-33-2, the publication is Russian Journal of General Chemistry (2021), 91(6), 1140-1146, database is CAplus.

A novel Fe₃O₄@Si-NHC-Pd catalyst with N-heterocyclic carbenes (NHCs) moiety as an alternative ligand to phosphines for metal complexes has been synthesized and characterized by various methods. Synthesis of metal nanoparticles has been accomplished without aggregation, and the prepared catalyst has been applied in the Suzuki-Miyaura cross-coupling reaction of boronic acids and aryl halides in water using Et₃N as a base. The catalyst has demonstrated high efficiency at room temperature and can be easily removed from the reaction media using an external magnetic field and recycled at least five times without significant decrease of its activity.

Russian Journal of General Chemistry published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, Quality Control of 613-33-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Appa, Rama Moorthy published the artcileStructure controlled Au@Pd NPs/rGO as robust heterogeneous catalyst for Suzuki coupling in biowaste-derived water extract of pomegranate ash, SDS of cas: 613-33-2, the publication is Applied Organometallic Chemistry (2021), 35(5), e6188, database is CAplus.

This article explored the aptness of water extract of pomegranate ash (WEPA) of agro-waste origin as an effective media for a heterogeneous reduced graphene oxide (rGO)-supported Au-Pd bimetallic nanoparticles (NPs)-catalyzed Suzuki coupling without the need of addnl. ligand, base, and additives at room temperature Morphol. and structural details of Au-Pd bimetallic nanoparticles/rGO were evaluated using a suite of electron microscopy, X-ray diffraction and cyclic voltammetry techniques. A facile chem. reduction method using methylamine borane as a reducing agent gave 5.8 nm-sized Au-Pd bimetallic particles on the rGO surface with an Au@Pd core-shell morphol. The structural, synergistic, and support capabilities offered by core-shell structured Au@Pd NPs/rGO could made a pos. contribution in achieving Suzuki coupling reactions in very short times (5-30 min) with a good to excellent yields of biaryls Ar¹Ar² [Ar¹ = Ph, 4-MeC₆H₄, 4-MeOC₆H₄, etc.; Ar² = Ph, 4-ClC₆H₄, 2,4-di-FC₆H₄, etc.] (91-99%). The catalyst had been easily recovered by phase separation and reused for three consecutive times without losing its effective catalytic property up to two cycles.

Applied Organometallic Chemistry published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, SDS of cas: 613-33-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia