Category: 6217-54-5

Rosenau, Simon published the artcileFeeding green: Spirulina (Arthrospira platensis) induced changes in production performance and quality of salmonid species, Application In Synthesis of 6217-54-5, the publication is Aquaculture Research (2022), 53(12), 4276-4287, database is CAplus.

Spirulina is an interesting candidate for fish nutrition. This study aims to investigate the effect of the complete replacement of fishmeal with spirulina (Arthrospira platensis) in the diets of brook trout (Salvelinus fontinalis), rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta fario), in relation to growth and product quality. Two isoenergetic and isonitrogenous exptl. diets containing either fishmeal or spirulina as a main source of protein were used for a 10-wk feeding trial. Differences in the spirulina acceptance and conversion between species were observed The exptl. diets were well accepted except for brown trout. A species-diet interaction was observed, which led to a reduction in final body weight due to the spirulina supplementation for brook and rainbow trout (p$$ p $$ < 0.05). Parallel, the feed conversion ratio increased to the same extent in the spirulina-fed fish (p$$ p $$ < 0.05), fostering the assumption, that both species did not differ in converting the spirulina diet. Spirulina led to a significant increase (p$$ p $$ < 0.05) in yellow and red coloration in both raw and cooked fillets. The diet had a significant effect on the fatty acid profile, resulting in an increase in SFA and MUFA, while PUFA levels decreased significantly in spirulina-fed fish (p$$ p $$ < 0.05). Overall, total replacement of fishmeal with Spirulina goes along with a reduced production performance and effects on major product quality traits such as fillet color and fatty acid pattern. In particular, consumer acceptance of the yellow fillet color should be further investigated.

Aquaculture Research published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Application In Synthesis of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chen, Wei published the artcileDHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1alpha signaling, Related Products of catalysis-chemistry, the publication is BMC Biology (2022), 20(1), 39, database is CAplus and MEDLINE.

Obesity leads to a decline in the exercise capacity of skeletal muscle, thereby reducing mobility and promoting obesity-associated health risks. Dietary intervention has been shown to be an important measure to regulate skeletal muscle function, and previous studies have demonstrated the beneficial effects of docosahexaenoic acid (DHA; 22:6 ¦Ø-3) on skeletal muscle function. At the mol. level, DHA and its metabolites were shown to be extensively involved in regulating epigenetic modifications, including DNA methylation, histone modifications, and small non-coding microRNAs. However, whether and how epigenetic modification of mRNA such as N6-methyladenosine (m6A) mediates DHA regulation of skeletal muscle function remains unknown. Here, we analyze the regulatory effect of DHA on skeletal muscle function and explore the involvement of m6A mRNA modifications in mediating such regulation. DHA supplement prevented HFD-induced decline in exercise capacity and conversion of muscle fiber types from slow to fast in mice. DHA-treated myoblasts display increased mitochondrial biogenesis, while slow muscle fiber formation was promoted through DHA-induced expression of PGC1¦Á. Further anal. of the associated mol. mechanism revealed that DHA enhanced expression of the fat mass and obesity-associated gene (FTO), leading to reduced m6A levels of DNA damage-induced transcript 4 (Ddit4). Ddit4 mRNA with lower m6A marks could not be recognized and bound by the cytoplasmic m6A reader YTH domain family 2 (YTHDF2), thereby blocking the decay of Ddit4 mRNA. Accumulated Ddit4 mRNA levels accelerated its protein translation, and the consequential increased DDIT4 protein abundance promoted the expression of PGC1¦Á, which finally elevated mitochondria biogenesis and slow muscle fiber formation. DHA promotes mitochondrial biogenesis and skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1¦Á signaling, protecting against obesity-induced decline in skeletal muscle function.

BMC Biology published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Erb, Sophia J. published the artcileresponsiveness of PNPLA3 and lipid-related transcription factors is dependent upon fatty acid profile in primary bovine hepatocytes, Computed Properties of 6217-54-5, the publication is Scientific Reports (2022), 12(1), 888, database is CAplus and MEDLINE.

Knockdown of patatin-like phospholipase domain-containing protein 3 (PNPLA3) increased triglycerides (TG) in primary bovine hepatocytes, suggesting that PNPLA3 plays a causal role in hepatic TG clearing. In vivo, PNPLA3 abundance across the periparturient period is inversely related to hepatic TG accumulation and circulating fatty acid (FA) concentrations The purpose of this research was to determine if PNPLA3, as well as other lipases, transcription factors, or FA-mediated genes, are regulated by FA mimicking liver lipid accumulation (ACCUM) and liver lipid clearing (RECOV) or singular FA physiol. found in dairy cows at 0.5 mM of circulating RECOV (iRECOV). Abundance of PNPLA3 tended to decrease with ACCUM and increased quadratically with RECOV (P ¡Ü 0.10), differing from PNPLA3 expression, but consistent with previous in vivo research. Adipose TG lipase abundance, but not other lipase abundances, was quadratically responsive to both ACCUM and RECOV (P ¡Ü 0.005). Abundance of PNPLA3 and SREBP1c and expression of LXRA responded similarly to iRECOV, with C18:0 tending to decrease abundance (P ¡Ü 0.07). Result indicate that bovine PNPLA3 is translationally regulated by FA and although a LXRA-SREBP1c pathway mediation is possible, the mechanism warrants further investigation.

Scientific Reports published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Computed Properties of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lozano-Munoz, Ivonne published the artcileHerbivorous fish (Medialuna ancietae) as a sustainable alternative for nutrition security in Northern Chile, Synthetic Route of 6217-54-5, the publication is Scientific Reports (2022), 12(1), 1619, database is CAplus and MEDLINE.

Sustainability in aquaculture is a necessity of the future, not only as the most promising means of supplying the protein that the world will require to feed its growing population but to offer needed conservation of the world¡äs ocean resources. The use of wild fish inputs in farm-raised fish outputs has been a primary concern of sustainability in aquaculture production Herbivorous fish are more efficient converters of protein into fish flesh. Species of the genus Medialuna fish have been reported as a fast-growing, short-lived species. The native fish Acha (Medialuna ancietae Chirichigno 1987) in the Northern part of Chile is an over-exploited fish that has been associated with aquatic vegetation as a food source. We studied the feeding habits and nutritional composition of M. ancietae. For this, we developed a reference collection of marine macroalga (epidermis and nutritional composition) observed in the diet of individuals of this species for the study of digestive material. More than 90% of the components found were marine macroalgae, indicating that M. ancietae is an herbivorous fish. Compared to non-herbivorous fish our results showed that most of the nutrients present in the Medialuna diet are found at much lower levels including n-3 long-chain polyunsaturated fatty acids (49.7%) and protein (13-60%). M. ancietae meat provides essential components of human nutrition with a significant protein content (18.99 ¡À 0.26%) and 268 ¡À 5.9 mg/100 g of the essential n-3 long-chain polyunsaturated fatty acids. Most fed aquaculture non-herbivorous species rely on wild-captured fish for these essential nutrients, while M. ancietae can obtain and concentrate them from potentially cultivable macroalgae. M. ancietae has potential for sustainable aquaculture production as a contribution to nutrition security and the re-stocking of wild populations.

Scientific Reports published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Synthetic Route of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sefi, Mediha published the artcileAntioxidant role of selenium against maneb-induced cardiotoxicity in mice, Quality Control of 6217-54-5, the publication is Environmental Science and Pollution Research (2022), 29(36), 54827-54841, database is CAplus and MEDLINE.

The current study was conducted to assess the beneficial effect of selenium (Se) on maneb-induced cardiotoxicity and fatty acid alterations in adult mice. Swiss albino male mice were assigned into four exptl. groups. The first group consisted of neg. controls. The second group represented the pos. controls where mice received daily, via the diet, sodium selenite at a dose of 0.2 mg/kg. For the third group, mice were subjected to i.p. injections of maneb (30 mg/kg BW). The fourth group (MB+Se) received daily the same dose of maneb as group 3 along with sodium selenite at the same dose as group 2. Mice exposure to maneb caused cardiotoxicity as indicated by an increase in malondialdehyde, hydrogen peroxide, and protein carbonyl levels, and an alteration of the antioxidant defense system (catalase, glutathione peroxidase, superoxide dismutase, glutathione, and vitamin C). Plasma lactate dehydrogenase activity and total cholesterol, triglyceride, and low-d. lipoprotein cholesterol levels increased, while high-d. lipoprotein cholesterol level decreased. Results showed also a decrease in the amount of n-3 PUFA, docosahexaenoic, docosapentaenoic, and eicosapentaenoic acids. However, an increase in the levels of MUFA, cis-vaccenic, and palmitoleic acids was observed Co-administration of Se restored the parameters indicated above to near control values. The histopathol. findings confirmed the biochem. results. Selenium could be a useful and efficient agent against maneb-induced cardiotoxicity.

Environmental Science and Pollution Research published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C9H8BNO2, Quality Control of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Brown, Robert W. published the artcileNutrient (C, N and P) enrichment induces significant changes in the soil metabolite profile and microbial carbon partitioning, Name: Docosahexaenoic Acid, the publication is Soil Biology & Biochemistry (2022), 108779, database is CAplus.

The cycling of soil organic matter (SOM) and carbon (C) within the soil is governed by the presence of key macronutrients, particularly nitrogen (N) and phosphorus (P). The relative ratio of these nutrients has a direct effect on the potential rates of microbial growth and nutrient processing in soil and thus is fundamental to ecosystem functioning. However, the effect of changing soil nutrient stoichiometry on the small organic mol. (i.e., metabolite) composition and cycling by the microbial community remains poorly understood. Here, we aimed to disentangle the effect of stoichiometrically balanced nutrient addition on the soil metabolomic profile and apparent microbial carbon use efficiency (CUE) by adding a labile C source (glucose) in combination with N and/or P. After incorporation of the added glucose into the microbial biomass (48 h), metabolite profiling was undertaken by ultra-performance liquid chromatog.-tandem mass spectrometry (UPLC-MS/MS). 494 metabolites were identified across all treatments mainly consisting of lipids (n = 199), amino acids (n = 118) and carbohydrates (n = 43), >97% of which showed significant changes in concentration between at least one treatment. Overall, glucose-C addition generally increased the synthesis of other carbohydrates in soil, while addition of C and N together increased peptide synthesis, indicative of protein formation and turnover. The combination of C and P significantly increased the number of fatty acids synthesized. There was no significant change in the PLFA-derived microbial community structure or microbial biomass following C, N and P addition Further, N addition led to an increase in glucose-C partitioning into anabolic processes (i.e., increased CUE), suggesting the microbial community was N, but not P limited. Based on the metabolomic profiles observed here, we conclude that inorganic nutrient enrichment causes substantial shifts in both primary and secondary metabolism within the microbial community, leading to changes in resource flow and thus soil functioning, however, the microbial community illustrated significant metabolic flexibility.

Soil Biology & Biochemistry published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Name: Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Cui, Jingtao published the artcileComprehensive lipid profiles of sea cage aquaculture cobia (Rachycentron canadum) based on lipidomics, Application In Synthesis of 6217-54-5, the publication is Journal of Food Composition and Analysis (2022), 104664, database is CAplus.

Cobia (Rachycentron canadum) is a significant fish species for mariculture with high nutritional value. This research aims to comprehensively investigate the lipid profiles of cobia tissues, including fatty acid profiles, characteristics of phospholipids (PL) and triacylglycerols (TAG), and lipid mol. species. The results showed that cobia contained high levels of total lipids (2.89 -32.09% of wet weight), docosahexaenoic acid (DHA, 10.83 -14.69% of total fatty acids) and eicosapentaenoic acid (EPA, 3.54 -9.68%). Compared with TAG, higher levels of polyunsaturated fatty acids, DHA/EPA in particular, were concentrated in PL. Interestingly, DHA was predominantly distributed in the sn-1 position of PL and the sn-2 position of TAG, whereas EPA was predominantly distributed in the external positions of PL and TAG. Addnl., at least 693 mol. species from 23 subclasses were identified by ultrahigh-performance liquid chromatog.-quadrupole exactive-mass spectrometry (UPLC-Q-Exactive-MS). Glycerophospholipids (63.19 -66.61%) and glycerolipids (19.17 -22.21%) were the major lipid classes in cobia tissues, and the majority of them contained DHA and EPA. Hence, this comprehensive anal. will help to evaluate the lipid nutritional values and facilitate exploitation in cobia consumption and processing.

Journal of Food Composition and Analysis published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Application In Synthesis of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kielbasa, Anna published the artcileA novel non-derivatization HPLC/UV method for the determination of some n-3 free fatty acids in breast milk matrix, Recommanded Product: Docosahexaenoic Acid, the publication is Microchemical Journal (2022), 107789, database is CAplus.

The mother¡ä s milk is a valuable source of many nutrients, including fatty acids (FAs). The most important fatty acids are polyunsaturated fatty acids (PUFAs), including linoleic and alpha-linolenic acids (ALA) that are essential for humans, as well as fatty acids that are formed by desaturation and elongation, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that occur in small amounts in breast milk. The content of exogenous fatty acids in milk is influenced by maternal age, genetics, hormones, infections, metabolic disorders, medications, dietary habits, supplementation, adiposity, lactation stage, feeding method, intervals between breastfeeding, and duration of breastfeeding. The proposed method for isolating fatty acids from breast milk has a recovery rate of 80-92% (SD of 4-9). Most importantly, derivatization to Me esters is not necessary. Due to low limits of detection (e.g. 0.009¦Ìg/mL of milk for DHA) and quantification (e.g. 0.090 ¦Ìg/mL of milk for DHA), as well as high linearity (R2 = 0.9997), this method can be effectively used to identify and quantify three unsaturated fatty acids in breast milk using HPLC/UV. The developed method for the isolation and determination of PUFAs in breast milk can be widely applied in routine research, e.g. in milk banks.

Microchemical Journal published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Recommanded Product: Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bandara, Tharindu published the artcileSeawater browning alters community composition and reduces nutritional quality of plankton in a subarctic marine ecosystem, SDS of cas: 6217-54-5, the publication is Canadian Journal of Fisheries and Aquatic Sciences (2022), 79(8), 1291-1301, database is CAplus.

Inflows of colored terrestrial organic matter cause seawater browning and reduced phytoplankton production in subarctic coastal ecosystems, potentially deteriorating the nutritional quality of marine food webs. We analyzed the fatty-acid (FA) compositions of seston and the zooplankton taxa Eurytemora affinis and cladocerans at three locations of the northern Baltic Sea. At the coastal and northerly locations, salinity and phosphorus concentrations were low, while concentrations of humic substances (i.e., terrestrial organic matter) were high. The southerly location showed the opposite trend. The ratio between alga-specific ¦Ø3 polyunsaturated FA and terrigenous monounsaturated FA (MUFA) in Eurytemora decreased from south to north, as did the ratio between the alga-specific docosahexaenoic acid (DHA) and terrigenous MUFA in cladocerans. With increasing humic substances, the biomass of DHA-rich phytoplankton decreased and the zooplankton MUFA content increased. Our results indicate that colored terrestrial organic matter alters the phytoplankton composition, consequently affecting the zooplankton nutritional quality.

Canadian Journal of Fisheries and Aquatic Sciences published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, SDS of cas: 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Forteza, Fabiola published the artcileInfluence of diet on acute endocannabinoidome mediator levels post exercise in active women, a crossover randomized study, Synthetic Route of 6217-54-5, the publication is Scientific Reports (2022), 12(1), 8568, database is CAplus and MEDLINE.

The extended endocannabinoid system, also termed endocannabinoidome, participates in multiple metabolic functions in health and disease. Phys. activity can both have an acute and chronic impact on endocannabinoid mediators, as does diet. In this crossover randomized controlled study, we investigated the influence of diet on the peripheral response to acute maximal aerobic exercise in a sample of active adult women (n = 7) with no underlying metabolic conditions. We compared the impact of 7-day standardized Mediterranean diet (MedDiet) and control diet inspired by Canadian macronutrient intake (CanDiet) on endocannabinoidome and short-chain fatty acid metabolites post maximal aerobic exercise. Overall, plasmatic endocannabinoids, their congeners and some polyunsaturated fatty acids increased significantly post maximal aerobic exercise upon cessation of exercise and recovered their initial values within 1 h after exercise. Most N-acylethanolamines and polyunsaturated fatty acids increased directly after exercise when the participants had consumed the MedDiet, but not when they had consumed the CanDiet. This impact was different for monoacylglycerol endocannabinoid congeners, which in most cases reacted similarly to acute exercise while on the MedDiet or the CanDiet. Fecal microbiota was only minimally affected by the diet in this cohort. This study demonstrates that endocannabinoidome mediators respond to acute maximal aerobic exercise in a way that is dependent on the diet consumed in the week prior to exercise.

Scientific Reports published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Synthetic Route of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia