Category: 6972-05-0

Elstner, R. published the artcileStudies on the effect of inhibitors in ammonia etching solutions on the depth and pattern in copper etching, Product Details of C3H8N2S, the publication is Metalloberflaeche (1982), 36(10), 468-78, database is CAplus.

The effects of inhibitors on the etching of Cu for printed circuits by ammoniacal solutions of Na chlorite and CuCl₂ were studied. The etch rates and elec. conductivity of the different solutions are given. The effects of Cu(I) ions are discussed. The optimum etching conditions are described.

Metalloberflaeche published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Product Details of C3H8N2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sarigueney, Ahmet Burak published the artcileSynthesis and Antimicrobial Activity of Some 2-aminothiazole and 2-aminothiadiazine Derivatives, Synthetic Route of 6972-05-0, the publication is Journal of Heterocyclic Chemistry (2018), 55(9), 2107-2110, database is CAplus.

A series of thiazoles I [R¹ = NH₂, NHMe, NMe₂, NHPh], bis-thiazole II [R¹ = NH₂], thiadiazines III and bis-thiadiazine IV [R¹ = NH₂] was synthesized from reaction of phenoxy chloroacetophenone with thioureas and thiosemicarbazides resp. The synthesized compounds I, II, III and IV were characterized by spectroscopic techniques and evaluated as potential antimicrobial agents. The synthesized compounds were evaluated for thier antibacterial activity by broth microdilution method and expressed as min. inhibitory concentration; against Escherichia coli, Salmonella typhimurium, Bacillus cereus, and Staphylococcus aureus. Results showed that compounds, I [R¹ = NHMe], II [R¹ = NH₂] and IV [R¹ = NH₂] were found to selectively inhibit Gram positives.

Journal of Heterocyclic Chemistry published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Synthetic Route of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nuna, Nobumitsu published the artcileDetection of tetramethylthiuram disulfide and related compounds using the chemiluminescence of tris (2,2′-bipyridyl) ruthenium (III) cation, Related Products of catalysis-chemistry, the publication is Bunseki Kagaku (2003), 52(9), 763-767, database is CAplus.

The chemiluminescence (CL) of tris(2,2′-bipyridyl)ruthenium(III) cation was applied to the determination of tetramethylthiuram disulfide (TMTD). A sample was injected to an HPLC system with Chromolith Performance RP-18e. The eluted sample and CL reagent were mixed, and sent to a CL-detector. The detection limit of TMTD using the HPLC system was 0.15 pmol (S/N= 3). The calibration curve was linear over the injection amount range from 0.6 to 20 pmol. To improve the sensitivity of the CL method, the water that generated the background was removed from the system. As a result, the sensitivity was improved.

Bunseki Kagaku published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gill, Dip Singh published the artcileA conductometric study of the complex formation between copper(I) perchlorate and some organic ligands in acetonitrile, Related Products of catalysis-chemistry, the publication is Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry (1998), 37A(12), 1079-1083, database is CAplus.

CuClO₄ solutions of different concentrations in MeCN were conductometerically titrated with solutions of thiourea (TU), N,N-dimethylthiourea (DMTU), N-phenylthiourea (NPTU), N,N-diphenylthiourea (DPTU), 1,10-phenanthroline (PHEN), 2,2′-bipyridine (BPY) and tri-Et phosphite (TEP) at 298 K. The plots of conductivity vs. moles of ligand added show significant decrease in conductivity followed by a region of almost constant conductivity The fall of conductivity in the cases of thiourea and substituted thioureas is linear while in all the other cases it is nonlinear. From these plots knowledge about the stoichiometry of the complexes formed between CuClO₄ and various ligands was derived. A 1:2 complex is observed between CuClO₄ and 1,10-phenanthroline and 2,2′-bipyridine and 1:4 complex with tri-Et phosphite. CuClO₄ forms complexes with thiourea and substituted thioureas, the stoichiometry of which strongly depends upon the concentrations of CuClO₄ and of the ligands used for the titration With N-phenylthiourea and N,N-diphenylthiourea, the complex formed has CuClO₄ to ligand ratio as 1:2 under the present conditions employed, while with thiourea and N,N-dimethylthiourea, the stoichiometry of the complexes formed between CuClO₄ and ligands is either 1:2 or 1:3 or 1:4 depending upon the conditions.

Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kim, Dong CHan published the artcileSynthesis of new thiazolium betaines and the ring expansion reaction via 1,4-dipolar cycloaddition, Category: catalysis-chemistry, the publication is Journal of Heterocyclic Chemistry (1995), 32(5), 1581-6, database is CAplus.

The 1,4-dipolar cycloaddition of 3-phenyl-7-[N-phenyl(carbamoyl)]-5,6-dihydroimidazo[2,1-b]thiazolium betaine (I) with a series of aliphatic alkylating agents such as Et bromoacetate, ¦Á-chloroacetone, and Et 4-chloroacetoacetate gave a variety of new ring-expanded cycloadducts. E.g., (12RS,13SR)-12-acetyl-2,4-dioxo-1,3,9-triphenyl-6,7-dihydro-12H-thiazino[3′,4′:2,3]imidazo[1,2-a][1,3,5]triazine was prepared in 38% yield from I and ¦Á-chloroacetone.

Journal of Heterocyclic Chemistry published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Koronkiewicz, Miroslawa published the artcileProapoptotic effects of new pentabromobenzylisothiouronium salts in a human prostate adenocarcinoma cell line, Recommanded Product: 1,1-Dimethylthiourea, the publication is Acta Poloniae Pharmaceutica (2012), 69(6), 1325-1333, database is CAplus and MEDLINE.

Prostate cancer is the second most common cancer in elderly men worldwide and its incidence rate is rising continuously. Agents capable of inducing apoptosis in prostate cancer cells seem a promising approach to treat this malignancy. In this study we describe the synthesis of a number of novel N- and N,N’-substituted S-2,3,4,5,6-pentabrornobenzylisothiouronium bromides and their activity against the human prostate adenocarcinoma PC3 cell line. All the compounds produced changes in mitochondrial transmembrane potential and cell cycle progression, showed a cytostatic effect and induced apoptosis in the tested cancer line in a concentrationand time-dependent manner. The most effective compounds ZKK-3, ZKK-9 and ZKK-13 produced, at 20 ¦ÌM concentration, apoptosis in 42, 46, and 66% of the cells, resp., after 48 h incubation. Two selected S-2,3,4,5,6-pentabromobenzylisothiouronium bromides (ZKK-3, ZKK-9) showed also a synergic proapoptotic effect with the new casein kinase II inhibitor 2-(4-methylpiperazin-l-yl)-4,5,6,7-tetrabromo-1H-benzimidazole (TBIPIP) in the PC3 cell line.

Acta Poloniae Pharmaceutica published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Recommanded Product: 1,1-Dimethylthiourea.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Batenko, Nelli G. published the artcileA new method for the synthesis of 2,5-bisheteroaryl-3,6-dichloro-1,4-benzoquinones, Safety of 1,1-Dimethylthiourea, the publication is Heterocycles (2005), 65(7), 1569-1576, database is CAplus.

A new method for the synthesis of sym. and asym. 2,5-bisheteroaryl-3,6-dichloro-1,4-benzoquinones with sulfur and/or nitrogen containing heterocycles has been elaborated on the basis of easily obtainable benzofuran.

Heterocycles published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Safety of 1,1-Dimethylthiourea.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hussein, Ahmad Q. published the artcileReactions of ¦Á-bromo isothiocyanates, Safety of 1,1-Dimethylthiourea, the publication is Chemische Berichte (1979), 112(6), 1956-72, database is CAplus.

The reactions of RR¹CBrNCS [I; R = R¹ = Me, RR¹ = (CH₂)₅, R, R¹ = Me₂CH, CO₂Me; Me₃C, Ph; H, Ph; Me₃C, Br] are described. I having ¦Â-H atoms (1st 3 compounds) eliminate HBr to form vinyl isothiocyanates, e.g., CH₂:CMeNCS. H₂O hydrolyzes I to carbonyl compounds RR¹CO. Whereas hard nucleophiles substitute the Br in I, soft nucleophiles add to the C atom of the NCS group. The chem. properties of the products, including heterocycles and geminal diisothiocyanates, are examined Me₂C:NC(S)NMe₂ shows hindered rotation about the C(S)-N and C:N bonds.

Chemische Berichte published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Safety of 1,1-Dimethylthiourea.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Taouss, Christina published the artcileStructure of the adducts methylthiourea: 1,4-dioxane (2:1) and 1,1-dimethylthiourea: morpholine (1:1), HPLC of Formula: 6972-05-0, the publication is Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences (2016), 71(8), 905-907, database is CAplus.

The adducts methylthiourea:1,4-dioxane (2:1) (1) and 1,1-dimethylthiourea:morpholine (1:1) (2) were prepared and their crystal structures determined In 1, hydrogen bonding involving the methylthiourea mols. leads to the formation of R²₂(8) rings and thence to mol. ribbons parallel to [110]. The dioxane mols. accept hydrogen bonds from the remaining NH groups, and their inversion symmetry means that they connect adjacent methylthiourea ribbons, forming a layer structure parallel to (11?1). In the packing of 2, dimethylthiourea dimers cannot link to each other because of the blocking effect of their Me groups, but instead are linked indirectly via morpholine mols., the NH groups of which are simultaneously hydrogen bond acceptors from the remaining NH function of dimethylthiourea and donors towards the sulfur atom of a neighboring dimer. The overall effect is to form broad ribbons parallel to the a axis, with the morpholine mols. occupying the peripheral positions. The morpholine oxygen atom of 2 is not involved in classical hydrogen bonds.

Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C9H6N2O2, HPLC of Formula: 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lin, Jiahui published the artcileEarly secreted antigenic target of 6-kDa of Mycobacterium tuberculosis induces transition of macrophages into epithelioid macrophages by downregulating iNOS/NO-mediated H3K27 trimethylation in macrophages, Category: catalysis-chemistry, the publication is Molecular Immunology (2020), 189-200, database is CAplus and MEDLINE.

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb). Granuloma is a pathol. feature of tuberculosis and is a tight immune cell aggregation caused by Mtb. The main constituent cells are macrophages and their derivative cells including epithelioid macrophages. However, the mol. mechanism of the transition has not been reported. The purpose of this study was to investigate whether early secreted antigenic target of 6-kDa (ESAT6) can induce the transition of bone marrow-derived macrophages (BMDMs) into epithelioid macrophages and its possible mol. mechanism. The recombinant ESAT6 protein was obtained from E.coli carrying esat6 gene after iso-Pr ¦Â-D-thiogalactopyranoside (IPTG) induction. BMDMs were isolated from bone marrow of mice hind legs. Cells viability was detected by Cell Counting Kit 8 (CCK8) assays. The expression levels of mRNA and proteins were detected by qPCR and Western blot, or evaluated by flow cytometry. The expression level of nitric oxide (NO) was measured with a nitric oxide indicator. ESAT6 could significantly induce mRNA and protein expression levels of a group of epithelioid macrophages marker mols. (EMMMs), including E-cadherin, junction plakoglobin, ZO1, desmoplakin, desmoglein 3 and catenin porteins, in BMDMs. These events could be abrogated in macrophage from TLR2 deficiency mice. ESAT6 could also markedly induce iNOS/NO production that could significantly inhibit trimethylation of H3K27 in the cells. ESAT6-induced expressions of epithelioid macrophages marker mols. were significantly inhibited in the presence of H3K27 histone demethylase inhibitor GSK J1. Furthermore, ROS scavenging agent N,N’-Dimethylthiourea (DMTU) could markedly inhibit the transition induced by ESAT6 in macrophages. This study demonstrates that ESAT6 bound with TLR2 can activate iNOS/NO and ROS signalings to reduce the trimethylation of H3K27 resulting in the increment of EMMMs expression that is beneficial to the transition of macrophages into epithelioid macrophages. However, hypoxia can inhibit this transition event. This study has provided new evidence of pathogenesis of granuloma caused by Mtb and also proposed new ideas for the treatment of TB.

Molecular Immunology published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia