Category: 6972-05-0

Yokoyama, Masataka published the artcileSynthesis of heterocycles using a new immonium salt derived from N,N-dimethylthiourea, Computed Properties of 6972-05-0, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1982), 1059-62, database is CAplus.

Treatment of Me₂NCSNH₂ with NaH, CS₂ and MeI in THF gave Me₂NC(SMe):N⁺MeCS₂Me I^– (I), which underwent cyclocondensation reactions with nucleophiles to give heterocycles including triazolines, an oxadiazole, a thiazole, a triazine, a benzoxadiazepine and a benzothiadiazepine. E.g., I was refluxed in EtOH with N₂H₄ for 4 h to give 74% triazolinethione II. Similar treatment of I with HSCH₂CO₂Et-LiN(CHMe₂)₂ in THF at -70° for 1 h and at room temperature for 1 h gave 47% thiazole III.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C14H28O5S, Computed Properties of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jahn, Ullrich published the artcile3,3-dichloroprop-2-eniminium salts (vinylogous Viehe salts). A study of their reactivity towards nucleophiles, HPLC of Formula: 6972-05-0, the publication is Synthesis (1997), 573-588, database is CAplus.

The title compounds, [Cl₂C:CC:N⁺R₂]Cl^– [I; R₂ = Me₂, (CH₂)₄, (CH₂)₂O(CH₂)₂, (CH₂)₅] react regioselectively at either the 1- or 3-position depending on the reaction pattern. Chloro substitution affording new propene iminium salts is preferred e.g. in the reaction with mercaptans, amines, and some activated arenes and hetarenes. Nucleophilic attack at the 1-position providing in allyl or allylidene structure is observed e.g. in the reaction with H₂O, EtOH, trialkyl phosphite, Me₃SiCN, Grignard reagents, and acceptor activated methylene compounds Reaction at both positions with heterocyclization to 1,3-thiazine-6-thiones occurs with thioamide functions. The regiochem. depends on a complex interplay of several factors in contrast to the FMO predicted orientation. The utility of I and some consecutive products as versatile C₃-building blocks for further syntheses is foreseeable.

Synthesis published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, HPLC of Formula: 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia