Catalysis-chemistry

Polyamine conjugates of meso-tritolylporphyrin and protoporphyrin IX: Potential agents for photodynamic therapy of cancers was written by Sol, Vincent;Lamarche, Francois;Enache, Michaela;Garcia, Guillaume;Granet, Robert;Guilloton, Michel;Blais, J. C.;Krausz, Pierre. And the article was included in Bioorganic & Medicinal Chemistry in 2006.Computed Properties of C47H36N4O The following contents are mentioned in the article:

An efficient five-step synthesis method was developed to obtain tritolylporphyrin and protoporphyrin IX polyamine conjugates. These compounds were composed of either one polyamine unit (spermidine or spermine) covalently tethered to monocarboxyphenyl tritolylporphyrin or two mols. of polyamines borne by protoporphyrin IX. In each compound, an aliphatic spacer arm is linked to the N ⁴ polyamine position. Photocytotoxicity of these new compounds was evaluated against K562 human chronic myelogenous leukemia cells and compared to Photofrin II; protoporphyrin IX polyamine conjugates exhibited much stronger photocytocicity than Photofrin II and were shown to readily induce necrosis in treated cells. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Computed Properties of C47H36N4O).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligand, in chemistry, any atom or molecule attached to a central atom, usually a metallic element, in a coordination or complex compound. Replacing precious metals with cheaper and more environmentally friendly metals is regarded as a highly desirable goal in the field of catalysis.Computed Properties of C47H36N4O

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Carbon Nanotubes with Covalently Linked Porphyrin Antennae: Photoinduced Electron Transfer was written by Baskaran, Durairaj;Mays, Jimmy W.;Zhang, X. Peter;Bratcher, Matthew S.. And the article was included in Journal of the American Chemical Society in 2005.SDS of cas: 57412-08-5 The following contents are mentioned in the article:

Single- and multiwalled carbon nanotubes have been covalently functionalized with free-base porphyrin. The quantity of porphyrin linked to the surface was determined from thermogravimetric and UV-vis anal. A reversible protonation equilibrium between the attached porphyrin and the residual acid groups of the carbon nanotubes has been identified. Steady-state fluorescence emission spectrum of the solutions of porphyrin-linked carbon nanotubes shows that the porphyrins act as energy absorbing and electron transferring antennae, and the carbon nanotubes act as efficient electron acceptors. The porphyrin-linked carbon nanotubes show 95-100% emission quenching, indicating a fast photoinduced electron transfer. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5SDS of cas: 57412-08-5).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligand, in chemistry, any atom or molecule attached to a central atom, usually a metallic element, in a coordination or complex compound. The ability of ligands to engender a variety of useful properties of organometallic complexes is the major enabling force for the discovery of new catalytic reactions, activation of small molecules, dramatically enhanced reactivity.SDS of cas: 57412-08-5

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Catalytic studies of 2-benzthiazolethiol (BzTa)-linked manganese(III) and cobalt(II) porphyrin complexes was written by He, Hong-Shan;Fang, Bai-Shan;Huang, Jin-Wang;Ji, Liang-Nian. And the article was included in Transition Metal Chemistry (Dordrecht, Netherlands) in 2000.Synthetic Route of C47H36N4O The following contents are mentioned in the article:

Four 2-benzthiazolethiol (BzTa)-linked porphyrins [I; R = H, Me, OMe, Cl (1)-(4)], and their complexes with Co^II and Mn^III, (5)-(12), were prepared and characterized by elemental anal., ¹H-NMR, IR, UV-visible and mass spectra. The hydroxylation of cyclohexane in the presence of these complexes and PhIO under mild conditions was investigated. The catalytic activities of these complexes were higher than that of corresponding TPPMn^IIICl and TPPCo^II species, resp., which indicated that the terminal group, BzTa, played an important role in the catalysis. A possible mechanism is proposed. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Synthetic Route of C47H36N4O).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligands are classified based on the number of lone pair electrons available for the central metal atom, size and charge like anionic, cationic, neutral, monodentate, bidentate, polydentate ligands. The ability of ligands to engender a variety of useful properties of organometallic complexes is the major enabling force for the discovery of new catalytic reactions, activation of small molecules, dramatically enhanced reactivity.Synthetic Route of C47H36N4O

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

An efficient route to VEGF-like peptide porphyrin conjugates via microwave-assisted ‘click-chemistry’ was written by Bakleh, M. E.;Sol, V.;Estieu-Gionnet, K.;Granet, R.;Deleris, G.;Krausz, P.. And the article was included in Tetrahedron in 2009.SDS of cas: 57412-08-5 The following contents are mentioned in the article:

Synthetic cyclopeptides, and particularly those derived from vascular endothelial growth factor (VEGF) sequence, present considerable interest for the development of nanodevices devoted to tumor imaging or targeting. In order to provide selective peptide-targeted tetrapyrrolic structures, the authors designed two meso-porphyrin derivatives anchored to a 17-residue-long cyclopeptide, potent antagonist of VEGF receptors, via a flexible tetraethylene glycol chain. Anchoring was achieved by two different strategies: a classical secondary amide bond formation and microwave-assisted Cu(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition (click-chem.). These compounds appear to be promising candidates for applications in photodynamic therapy (PDT). This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5SDS of cas: 57412-08-5).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligand, in chemistry, any atom or molecule attached to a central atom, usually a metallic element, in a coordination or complex compound. Chiral compounds with high purities and ee values are often used as ligands for catalytically active metal complexes. SDS of cas: 57412-08-5

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Synthesis and structural analysis of novel glycosylated meso-arylporphyrins for application to cancer phototherapy was written by Gaud, Olivier;Granet, Robert;Kaouadji, Mourad;Krausz, Pierre;Blais, Jean Claude;Bolbach, Gerard. And the article was included in Canadian Journal of Chemistry in 1996.SDS of cas: 57412-08-5 The following contents are mentioned in the article:

The synthesis of 13 novel meso-glycosylarylporphyrins where the carbohydrate moiety is separated from the aryl substituent by a spacer arm is described. These compounds were synthesized by different methods, either by direct glycosylation of the ortho- or para-hydroxyalkoxyarylporphyrin or by condensation of glycosylated aldehyde with pyrrole or meso-(p-tolyl)dipyrromethane. In all cases, a ¦Â configuration was observed Deprotection of the sugar then followed in a basic medium. A detailed ¹H and ¹³C NMR study allowed complete structural determination The UV-visible and laser desorption mass spectra are presented. Due to their sensitizing abilities, these resultant compounds are of considerable interest for photodynamic therapy. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5SDS of cas: 57412-08-5).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. The atoms and molecules used as ligands are almost always those that are capable of functioning as the electron-pair donor in the electron-pair bond (a coordinate covalent bond) formed with the metal atom. The ability of ligands to engender a variety of useful properties of organometallic complexes is the major enabling force for the discovery of new catalytic reactions, activation of small molecules, dramatically enhanced reactivity.SDS of cas: 57412-08-5

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Chain-length dependence of photoelectric conversion from a porphyrin monolayer modified electrode was written by Yu, Jun-Hua;Li, Fu-You;Wang, Xue-Song;Huang, Yanyi;Zhang, Bao-Wen;Huang, Chun-Hui;Cao, Yi. And the article was included in Optical Materials (Amsterdam, Netherlands) in 2003.COA of Formula: C47H36N4O The following contents are mentioned in the article:

The photoelectrochem. of a series of porphyrins containing an alkyl chain terminated with imidazolyl, is described. Indium-tin oxide electrodes deposited with porphyrins using the Langmuir-Blodgett (LB) technique exhibit high photocurrent values under ambient condition. Action spectra of the photocurrent generation are coincident with the absorption of the LB film-modified electrodes, indicating that the dye aggregates in the LB film are responsible for the photocurrent. The bias voltages that may influence the photocurrent have also been investigated. The photocurrents varied with the side chain length; the compound with a longer chain but not with the shortest chain generated the maximum photocurrent. To interpret such a special case, a possible mechanism is suggested. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5COA of Formula: C47H36N4O).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. The atoms and molecules used as ligands are almost always those that are capable of functioning as the electron-pair donor in the electron-pair bond (a coordinate covalent bond) formed with the metal atom. The actual catalysts are metal complexes that are prepared from ligands and appropriate metal precursors.COA of Formula: C47H36N4O

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Light-induced electron transfer and charge separation of porphyrin compounds for photoelectric conversion was written by Cao, Yi;Zhang, Bao-Wen;Qian, Wen-Yuan;Bai, Jian-Wei;Xiao, Xu-Rui;Jia, Jian-Guang. And the article was included in Journal of the Chinese Chemical Society (Taipei) in 1995.Related Products of 57412-08-5 The following contents are mentioned in the article:

A series of artificial photosynthesis porphyrin compounds consisting of electron donor and electron acceptor were synthesized. Their spectroscopic behaviors in solution were investigated and the synthetic mol. devices were prepared with these mols. by using LB technique. It was indicated that multistep electron transfer and charge separation for these compounds actually occur, which is of great advantage of their photoelec. conversion. An efficient energy transfer process takes place for one of the compounds A mechanism involving photoinduced electron transfer and multistep charge separation for these compounds was suggested. With only one monolayer of tetrad compound LB film on the surface of SnO₂ conductive glass, high photo-driven voltage and current were obtained. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Related Products of 57412-08-5).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligands, especially phosphines and carbenes, can play a key role in modifying and controlling homogeneous organometallic catalysts. The actual catalysts are metal complexes that are prepared from ligands and appropriate metal precursors.Related Products of 57412-08-5

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Novel phosphoramidates with porphine and nitrogenous drug: One-pot synthesis and orientation to cancer cells was written by Wang, Zhi-Wei;Guo, Can-Cheng;Xie, Wen-Zhong;Liu, Chao-Zhou;Xiao, Chun-Guang;Tan, Ze. And the article was included in European Journal of Medicinal Chemistry in 2010.Category: catalyst-ligand The following contents are mentioned in the article:

One-pot synthesis of novel phosphoramidates with porphine and nitrogenous drug was accomplished. In the absence of light, MTT test showed that they killed the BEL-7402 liver cancer cells effectively in vitro. The cell viability studied on normal liver and cancer cells showed that porphine phosphoramidates selectively kill the cancer cells, which was in sharp contrast with the non-porphine containing compound 4-formylphenyl N,N-bis(2-chloroethyl)-phosphoramidate. These results, coupled with the cell uptake test showing that they could differentiate the tumor cells from the normal cells by their selective accumulation in cancer cells, gave strong support to the notion that the introduction of porphine moiety in these mols. was responsible for the effectiveness and cell differentiability of these porphine phosphoramidates. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Category: catalyst-ligand).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Attachment of the ligand to the metal may be through a single atom, in which case it is called a monodentate ligand, or through two or more atoms, in which case it is called a didentate or polydentate ligand. It is clear that future advancements in metal complexes and their applications crucially depend on ligand design, whereas the ligand electronic, steric and topological properties provide numerous improvements to the reactivity and selectivity at the metal centers.Category: catalyst-ligand

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Synthesis and biological evaluation of thioglycosylated porphyrins for an application in photodynamic therapy was written by Sylvain, I.;Zerrouki, R.;Granet, R.;Huang, Y. M.;Lagorce, J.-F.;Guilloton, M.;Blais, J.-C.;Krausz, P.. And the article was included in Bioorganic & Medicinal Chemistry in 2001.Product Details of 57412-08-5 The following contents are mentioned in the article:

The aim of this work is the synthesis of a new family of glycosylated porphyrins in which the sugar moieties are linked to the tetrapyrrole ring by a thioglycosidic bond. Two series have been designed: the first one corresponds to meso-aryl porphyrin derivatives; the second one has been obtained from protoporphyrin IX derivatization. Aryl-porphyrins were prepared from tristolyl o- and p-hydroxyporphyrins followed by bromoallylation and thioglycosylation with peracetylated S-glucose, mannose and galactose and deprotection. The other series has been synthesized from protoporphyrin IX dimethylester with a regioselective glycosylation of terminal alkenyl carbon. The UV-visible, NMR and MALDI mass spectra are presented. Photocytotoxicities of the synthesized compounds against K562 chronic leukemia cell line has been evaluated. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Product Details of 57412-08-5).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Catalytic transformations have become a mainstay in the toolkit of the synthetic and increasing non-synthetic chemist alike. The actual catalysts are metal complexes that are prepared from ligands and appropriate metal precursors.Product Details of 57412-08-5

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Photoinduced electron transfer within porphyrin-anthraquinone dyads connected by Hamilton hydrogen bonding was written by Zhao, Xin;Chen, Jinping;Zeng, Yi;Li, Yingying;Han, Yongbin;Li, Yi. And the article was included in Chinese Journal of Chemistry in 2010.Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol The following contents are mentioned in the article:

Porphyrin- or Zn-porphyrin-cyanuric acid conjugants (TPP-CA or ZnTPP-CA) and anthraquinone connected with the known Hamilton receptor (AQ-H) were synthesized. The supramol. dyads constructed via the AQ-H and TPP-CA/ZnTPP-CA exhibit 6 H bonds, which provide the association constant K_APP approx. (2.8 ¡À 0.3) ¡Á 10³ mol^-1/L in toluene. Selective excitation of the porphyrin/Zn porphyrin chromophores results in an electron transfer between TPP-CA/ZnTPP-CA and AQ-H within the supramol. assemblies, leading to an efficient quenching of the TPP-CA/ZnTPP-CA fluorescence. The singlet electron transfer from porphyrin/Zn-porphyrin to anthraquinone proceeds mainly via a through space mechanism with efficiencies of 43%, 58%, and rate constants of 7.6 ¡Á 10⁷, 7.0 ¡Á 10⁸ s^-1, resp. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol).

4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligand design occupies a central place in organic synthesis and catalysis. Precious metals and metal oxides on carrier materials are used in many industrial processes as heterogenous catalysts.Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol

Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI