Tag: M.W=300-350

Tamoradi, Taiebeh published the artcileGd (III) and Tb (III) immobilized tryptophan functionalized magnetic nanoparticles for eco-friendly oxidation rections, Name: 2,2′-Dithiodibenzoic acid, the publication is Solid State Sciences (2019), 105981, database is CAplus.

In this study, Gd (III) and Td (III) immobilized magnetic nanocatalysts were prepared following a simple procedure using available materials. These nanoparticles were characterized by FT-IR, XRD, TGA, EDX, and ICP-OES studies and utilized in the S-oxidation reactions. It was observed that the rate of oxidation with Tb magnetic nanocatalyst was higher than that of Gd. Significant advantages of this environmental friendly process include short reaction times, high efficiency, and convenient recovery and reusability of the catalyst for several times without any significant loss of activity.

Solid State Sciences published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C5H7F3O3, Name: 2,2′-Dithiodibenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liao, Xiaoting published the artcileEffects of different sources of diet on the growth, survival, biochemical composition and physiological metabolism of clam (Cyclina sinensis), Safety of Docosahexaenoic Acid, the publication is Aquaculture Research (2022), 53(10), 3797-3806, database is CAplus.

It is essential to formulate artificial diets for Cyclina sinensis to satisfy the requirements of industrial aquaculture. We evaluated the effects of different dietary sources on the growth, survival, nutritional components, digestive performance and nonspecific immunity of C. sinensis. The diets of the three exptl. groups were as follows: natural bait (control group, CG), fermented Enteromorpha prolifea (EP) compound diet (Diet #1), and fermented Pyropia yezoensis (PY) compound diet (Diet #2). Feeding these diets did not affect the individuals final weight, specific growth rate and survival rate. The total amino acid and total monounsaturated fatty acid of individuals fed with Diet #1 were significantly higher than those provided with the other diets (p < 0.05). There were no significant differences in the activities of ¦Á-amylase, lipase, trypsin, total superoxide dismutase, lysozyme and acid phosphatase in the clam fed with different diets. In conclusion, the two fermented seaweed compound diets prepared herein can replace natural bait and meet the growth and developmental needs of C. sinensis. The fermented EP compound diet can improve the nutritional quality of the clam. This study lays a preliminary foundation for developing new artificial diets for clams and elucidates the further utilization of low-value seaweed resources.

Aquaculture Research published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Safety of Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

James, Anto published the artcileModeling the Adsorption of Polycyclic Aromatic Hydrocarbons on Graphynes: An Improved Lennard-Jones Formulation, Quality Control of 191-07-1, the publication is Journal of Physical Chemistry A (2022), 126(22), 3472-3485, database is CAplus and MEDLINE.

Research on the development of theor. methodologies for modeling noncovalent interactions governing the adsorption of polycyclic aromatic hydrocarbons (PAHs) on graphene and other two-dimensional materials is being intensely pursued in recent times. Highly accurate empirical potentials have emerged as a viable alternative to first-principles calculations for performing large-scale simulations. Herein, we report exploration of the potential energy surfaces for the adsorption of cata-condensed and peri-condensed PAHs on graphynes (GYs) using the improved Lennard-Jones (ILJ) potential. Initially, the ILJ potential is parametrized against benchmark electronic structure calculations performed on a selected set of PAH-GY complexes using dispersion-corrected d. functional theory. The accuracy of the parametrization scheme is then assessed by a comparison of the adsorption features predicted from the ILJ potential with those computed using electronic structure calculations The potential energy profiles as well as the single point energy calculations and geometry reoptimizations performed on the min.-energy configurations predicted by the ILJ potential for a broader range of PAH-GY complexes provided a validation of the parametrization scheme. Finally, by an extrapolation of the PAH adsorption energies on various GYs, we estimated the interlayer cohesion energies for the van der Waals bilayer heterostructures of GYs with graphene to be in the range of 25-50 meV/atom.

Journal of Physical Chemistry A published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Quality Control of 191-07-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tsuei, Michael published the artcileInterfacial Polyelectrolyte-Surfactant Complexes Regulate Escape of Microdroplets Elastically Trapped in Thermotropic Liquid Crystals, Quality Control of 71989-31-6, the publication is Langmuir (2022), 38(1), 332-342, database is CAplus and MEDLINE.

Polyelectrolytes adsorbed at soft interfaces are used in contexts such as materials synthesis, stabilization of emulsions, and control of rheol. Here, we explore how polyelectrolyte adsorption to aqueous interfaces of thermotropic liquid crystals (LCs) influences surfactant-stabilized aqueous microdroplets that are elastically trapped within the LC. We find that adsorption of poly(diallyldimethylammonium chloride) (PDDA) to the interface of a nematic phase of 4-cyano-4¡ä-pentylbiphenyl (5CB) triggers the ejection of microdroplets decorated with sodium dodecylsulfate (SDS), consistent with an attractive elec. double layer interaction between the microdroplets and LC interface. The concentration of PDDA that triggers release of the microdroplets (millimolar), however, is three orders of magnitude higher than that which saturates the LC interfacial charge (micromolar). Observation of a transient reorientation of the LC during escape of microdroplets leads us to conclude that complexes of PDDA and SDS form at the LC interface and thereby regulate interfacial charge and microdroplet escape. Poly(sodium 4-styrenesulfonate) (PSS) also triggers escape of dodecyltrimethylammonium bromide (DTAB)-decorated aqueous microdroplets from 5CB with dynamics consistent with the formation of interfacial polyelectrolyte-surfactant complexes. In contrast to PDDA-SDS, however, we do not observe a transient reorientation of the LC when using PSS-DTAB, reflecting weak association of DTAB and PSS and slow kinetics of formation of PSS-DTAB complexes. Our results reveal the central role of polyelectrolyte-surfactant dynamics in regulating the escape of the microdroplets and, more broadly, that LCs offer the basis of a novel probe of the structure and properties of polyelectrolyte-surfactant complexes at interfaces. We demonstrate the utility of these new insights by triggering the ejection of microdroplets from LCs using peptide-polymer amphiphiles that switch their net charge upon being processed by enzymes. Overall, our results provide fresh insight into the formation of polyelectrolyte-surfactant complexes at aqueous-LC interfaces and new principles for the design of responsive soft matter.

Langmuir published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C15H14O3, Quality Control of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Klingberg, Jenny published the artcilePolycyclic aromatic hydrocarbon (PAH) accumulation in Quercus palustris and Pinus nigra in the urban landscape of Gothenburg, Sweden, Application In Synthesis of 191-07-1, the publication is Science of the Total Environment (2022), 150163, database is CAplus and MEDLINE.

Trees have the potential to improve urban air quality as leaves and needles capture air pollutants from the air, but further empirical data was requested to quantify these effects. We measured the concentration of 32 polycyclic aromatic hydrocarbons (PAHs) in leaves of pin oak (Quercus palustris) and needles of black pine (Pinus nigra) in the City of Gothenburg, Sweden, during the summer of 2018. Oak leaves were collected twice (June, Sept.), while one-year-old (C + 1) and three-year-old (C + 3) pine needles were sampled in June to study the temporal development of leaf/needle PAH concentrations Specific leaf area (SLA) was estimated, which permitted calculation of leaf/needle area-based PAH content that were compared with the mass-based concentration In addition, the air concentration of PAHs and NO₂ was measured using passive samplers. There was a strong correlation between air concentrations of PAH and NO₂, indicating that the pollutants to a large degree originate from the same sources. In the oak leaves there was a significant decrease in low mol. mass PAHs (L-PAH, mainly gaseous) between June and Sept., but a significant increase in high mol. mass PAHs (H-PAH, mainly particle-bound). There was a strong correlation between L-PAH concentration in leaves and in air indicating an influence of equilibrium processes between ambient air and leaf. In the pine needles, there was a significant increase of both L-PAH and H-PAH in three-year-old needles compared to one-year-old needles. Pine was superior to oak in accumulating PAHs from the air, especially for L-PAHs when comparing area-based content. However, H-PAH concentrations were higher in oak leaves compared to pine needles on a leaf mass basis, emphasizing the importance of how concentrations are expressed. The results from this study can contribute to the development of urban planning strategies regarding the effect of vegetation on air quality.

Science of the Total Environment published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Application In Synthesis of 191-07-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Solomon, Michael published the artcileA coupled fluorometric rate assay for pyruvate dehydrogenase in cultured human fibroblasts, Category: catalysis-chemistry, the publication is Analytical Biochemistry (1984), 141(2), 337-43, database is CAplus and MEDLINE.

A method for measuring the activity of the pyruvate dehydrogenase complex (PDC) by coupling acetyl-CoA production to acetylation of a fluorescent dye is described. Acetylation of cresyl violet acetate by pigeon liver acetyltransferase results in a shift of its fluorescence spectrum from ¦Ë_ex?_max = 575, ¦Ë_em?_max = 620 nm to ¦Ë_ex?_max = 475, ¦Ë_em?_max = 575 nm (where ¦Ë = wavelength and ex and em = excitation and emission, resp.). The rate of appearance of acetylated dye was followed fluorometrically and was proportional to PDC activity in extracts of cultured human fibroblasts. The assay showed appropriate substrate and cofactor dependence and had a working range between 0.04 and 70 milliunits. It is 10-fold more sensitive than the spectrophotometric assay on which it is based (working range 0.4-31 milliunits) and is equally convenient. Unactivated PDC activity in fibroblast extracts was 0.75 (0.60-0.92) milliunits/mg protein (mean and range for 6 cell lines).

Analytical Biochemistry published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C17H20ClN3, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Han, Xiaoyue published the artcileA near-infrared fluorescent probe for sensitive detection and imaging of sulfane sulfur in living cells and in vivo, Formula: C14H10O4S2, the publication is Biomaterials Science (2018), 6(3), 672-682, database is CAplus and MEDLINE.

Sulfane sulfur refers to ionized sulfur that is reversibly attached to other sulfur atoms in the form of 6-valence electrons (S⁰). Sulfane sulfur possesses stronger nucleophilicity and reducibility than hydrogen sulfide in a series of physiol. reactions, which probably makes sulfane sulfur the actual signal mol. in cells. Herein, we designed and synthesized a near-IR (NIR) fluorescent probe BD-diSH for sensitive detection and imaging of sulfane sulfur in living cells and in vivo. The probe BD-diSH is composed of two moieties: the fluorophore azo-BODIPY and the sulfane sulfur recognition unit, viz., 2-mercapto benzoate. BD-diSH displayed high sensitivity and selectivity towards sulfane sulfur. The mercapto group (-SH) of 2-mercapto benzoic acid can nucleophilically capture the sulfur atom of thiosulfoxide tautomers in sulfane sulfur to form -SSH. The group -SSH will immediately induce intramol. cyclization reaction and release the azo-BODIPY fluorophore to emit NIR fluorescence. The probe BD-diSH was successfully applied to detect and image sulfane sulfur in the cytoplasm of the living cells. The results illustrated that the endogenous and exogenous sulfane sulfur level changed depending on different cell lines. BD-diSH was also capable of imaging the level changes of sulfane sulfur in mice. The above applications make our new probe a potential chem. tool for the study of physiol. and pathol. functions of sulfur sulfide in living cells and in vivo.

Biomaterials Science published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Formula: C14H10O4S2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Saima published the artcileBiocatalytic synthesis of diaryl disulphides and their bio-evaluation as potent inhibitors of drug-resistant Staphylococcus aureus, Category: catalysis-chemistry, the publication is Drug Development Research (2019), 80(1), 171-178, database is CAplus and MEDLINE.

Staphylococcus aureus is a WHO Priority II pathogen for its capability to cause acute to chronic infections and to resist antibiotics, thus severely impacting healthcare systems worldwide. In this context, it is urgently desired to discover novel mols. to thwart the continuing emergence of antimicrobial resistance. Disulfide containing small mols. has gained prominence as antibacterials. As their conventional synthesis requires tedious synthetic procedure and sometimes toxic reagents, a green and environmentally benign protocol for their synthesis has been developed through which a series of mols. were obtained and evaluated for antibacterial activity against ESKAPE pathogen panel. The hit compound was tested for cytotoxicity against Vero cells to determine its selectivity index and time-kill kinetics was determined The activity of hit was determined against a panel of S. aureus multi-drug resistant clin. isolates. Also, its ability to synergize with FDA approved drugs was tested as was its ability to reduce biofilm. We identified bis(2-bromophenyl) disulfide (2t) as possessing equipotent antimicrobial activity against S. aureus including MRSA and VRSA strains. Further, 2t exhibited a selectivity index of 25 with concentration-dependent bactericidal activity, synergized with all drugs tested and significantly reduced preformed biofilm. Taken together, 2t exhibits all properties to be positioned as novel scaffold for anti-staphylococcal therapy.

Drug Development Research published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

McCoy, Michael A. published the artcileBiophysical Survey of Small-Molecule ¦Â-Catenin Inhibitors: A Cautionary Tale, Name: Fmoc-Pro-OH, the publication is Journal of Medicinal Chemistry (2022), 65(10), 7246-7261, database is CAplus and MEDLINE.

The canonical Wingless-related integration site signaling pathway plays a critical role in human physiol., and its dysregulation can lead to an array of diseases. ¦Â-Catenin is a multifunctional protein within this pathway and an attractive yet challenging therapeutic target, most notably in oncol. This has stimulated the search for potent small-mol. inhibitors binding directly to the ¦Â-catenin surface to inhibit its protein-protein interactions and downstream signaling. Here, we provide an account of the claimed (and some putative) small-mol. ligands of ¦Â-catenin from the literature. Through in silico anal., we show that most of these mols. contain promiscuous chem. substructures notorious for interfering with screening assays. Finally, and in line with this anal., we demonstrate using orthogonal biophys. techniques that none of the examined small mols. bind at the surface of ¦Â-catenin. While shedding doubts on their reported mode of action, this study also reaffirms ¦Â-catenin as a prominent target in drug discovery.

Journal of Medicinal Chemistry published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Name: Fmoc-Pro-OH.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Allouche, Emmanuelle M. D. published the artcileN-Terminal selective C-H azidation of proline-containing peptides: A platform for late-stage diversification, Recommanded Product: Fmoc-Pro-OH, the publication is Chemistry – A European Journal (2022), 28(17), e202200368, database is CAplus and MEDLINE.

A methodol. for the C-H azidation of N-terminal proline-containing peptides was developed employing only com. available reagents. Peptides bearing a broad range of functionalities and containing up to 6 amino acids were selectively azidated at the carbamate-protected N-terminal residue in presence of the numerous other functional groups present on the mols. Post-functionalizations of the obtained aminal compounds were achieved: cycloaddition reactions or C-C bond formations via a sequence of imine formation/nucleophilic addition were performed, offering an easy access to diversified peptides.

Chemistry – A European Journal published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Recommanded Product: Fmoc-Pro-OH.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia