Tag: M.W=300-350

Rani, Anjeeta published the artcileProfiling the impact of choline chloride on the self-assembly of collagen mimetic peptide (Pro-Hyp-Gly)₁₀, SDS of cas: 71989-31-6, the publication is Process Biochemistry (Oxford, United Kingdom) (2022), 26-34, database is CAplus.

The promising applications of collagen in tissue engineering, regenerative medicine and biomaterials have intrigued great interest in development of collagen mimetic peptides (CMPs). In past decades, the large-scale collagen structures via the self-assembly of small CMPs have been extensively explored. Moreover, CMPs entail novel strategies in order to play a critical role in the discovery of new generation biomaterials. In this regard, we herein have synthesized a CMP, (Pro-Hyp-Gly)₁₀ i.e.POG10. CMP has been examined in the presence of varying concentration of choline chloride (ChCl) by using various biophys. techniques such as CD (CD), UV-vis spectroscopy, fluorescence spectroscopy, Fourier transform IR spectroscopy (FTIR) spectroscopy, differential scanning calorimetry (DSC), transmission electron microscopy (TEM) and dynamic light scattering (DLS). For the first time, we have demonstrated the use of choline chloride (ChCl) to manipulate stability and aggregation of CMP triple helixes in order to delineate the factors responsible for the stability of triple helixes.

Process Biochemistry (Oxford, United Kingdom) published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, SDS of cas: 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Temdee, Wattana published the artcileEffect of vacuum packaging on shelf-life extension of cooked and peeled harpiosquillid mantis shrimp (Harpiosquilla raphidea) during refrigerated storage, Recommanded Product: Docosahexaenoic Acid, the publication is International Journal of Food Science and Technology (2022), 57(7), 4451-4462, database is CAplus.

Effects of vacuum packaging (VP) on quality changes of cooked and peeled harpiosquillid mantis shrimp (HMS) during storage at 4¡ãC of 15 days were investigated. VP inhibited bacterial growth as ascertained by the lower rate of increases in total viable and psychrotrophic bacteria counts as well as other pathogenic and spoilage bacteria counts. VP samples had lower total volatile base and trimethylamine contents as compared to the sample packed in air (AP). Clostridium perfringens was undetectable in both samples. During storage, VP samples possessed lower pH than AP counterpart. Exudate and TCA-soluble peptide (TSP) contents of sample increased during the storage, regardless of packaging atmospheres. Fatty acid (FA) content, especially PUFA and MUFA, was decreased after 9 and 15 days of storage for AP and VP samples, resp. The cooked and peeled HMS contained 32 volatile organic compounds, consisting of several aldehydes and alcs. Carnobacterium and Pseudomonas were mainly involved in spoilage in samples as confirmed by next generation sequencing.

International Journal of Food Science and Technology published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C8H14O4, Recommanded Product: Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dewangan, Rikeshwer Prasad published the artcileCell-penetrating peptide conjugates of indole-3-acetic acid-based DNA primase/Gyrase inhibitors as potent anti-tubercular agents against planktonic and biofilm culture of Mycobacterium smegmatis, Safety of Fmoc-Pro-OH, the publication is Chemical Biology & Drug Design (2021), 98(5), 722-732, database is CAplus and MEDLINE.

Mycobacterium tuberculosis (Mtb) is a pathogenic bacterium that caused 1.5 million fatalities globally in 2018. New strains of Mtb resistant to all known classes of antibiotics pose a global healthcare problem. In this work, we have conjugated novel indole-3-acetic acid-based DNA primase/gyrase inhibitor with cell-penetrating peptide via cleavable and non-cleavable bonds. For non-cleavable linkage, inhibitor was conjugated with peptide via an amide bond to the N-terminus, whereas a cleavable linkage was obtained by conjugating the inhibitor through a disulfide bond. We performed the conjugation of the inhibitor either directly on a solid surface or by using solution-phase chem. M. smegmatis (non-pathogenic model of Mtb) was used to determine the minimal inhibitory concentration (MIC) of the synthetic conjugates. Conjugates were found more active as compared to free inhibitor mols. Strikingly, the conjugate also impairs the development of biofilm, showing a therapeutic potential against infections caused by both planktonic and sessile forms of mycobacterium species.

Chemical Biology & Drug Design published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Safety of Fmoc-Pro-OH.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Krasnov, Pavel O. published the artcileMolecular hydrogen sorption capacity of P216-schwarzite: PM6-D3, MP2 and QTAIM approaches, Safety of Coronene, the publication is Computational Materials Science (2022), 111410, database is CAplus.

Schwarzites, due to their high porosity, are among prospective materials for the sorption of different gases, including hydrogen. Their surface possesses neg. Gaussian curvature that intimately determines how many carbon atoms each hydrogen mol. will interact with, which, in turn, defines the fraction of hydrogen that would be sorbed in the schwarzite. The critical question about contributions to the sorption of the surface topol. and electronic effects is solved here. Within the framework of the QTAIM theory, the topol. parameters of the electron d. distribution function at the bond critical points characterizing the dispersion interaction of the H2 mol. with the carbon surface are estimated On the example of mols. [6]circulene and [7]circulene, it was shown that, despite the electronic effects arising from the bending of this surface, on average, the energy of phys. sorption of hydrogen obtained using MP2 calculations changes insignificantly – by about 0.1 kJ/mol in the case of, for example, vertical orientation of the mol. By calculating the thermochem. properties by the PM6-D3 method, the dependence of the weight fraction of hydrogen sorbed in P216-schwarzite on the external gas pressure and the temperature has been established. In particular, it was shown that at 300 K and 10 MPa, this value is 4.6%, slightly higher than other carbon nanostructures with similar d., porosity, and accessible surface area values.

Computational Materials Science published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Safety of Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Pigulski, Bartlomiej published the artcileFluorescence Enhancement by Supramolecular Sequestration of a C₅₄-Nanographene Trisimide by Hexabenzocoronene, Name: Coronene, the publication is Journal of the American Chemical Society (2022), 144(13), 5718-5722, database is CAplus and MEDLINE.

A supramol. trilayer nanographene complex consisting of a newly synthesized D_3h-sym. C₅₄-nanographene trisimide (NTI 1) and two hexabenzocoronenes (HBC) has been obtained by self-assembly. This 1:2 complex is structurally well-defined according to UV/vis and single crystal X-ray studies and exhibits high thermodn. stability even in polar halogenated solvents. Complexation of NTI 1 by two HBC mols. protects the NTI 1 ¦Ð-surface efficiently from oxygen quenching, thereby leading to a sequestration-induced fluorescence enhancement under ambient conditions.

Journal of the American Chemical Society published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Name: Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Luo, Na published the artcileDifferential regulation of intramuscular fat and abdominal fat deposition in chickens, Recommanded Product: Docosahexaenoic Acid, the publication is BMC Genomics (2022), 23(1), 308, database is CAplus and MEDLINE.

Chicken i.m. fat (IMF) content is closely related to meat quality and performance, such as tenderness and flavor. Abdominal fat (AF) in chickens is one of the main waste products at slaughter. Excessive AF reduces feed efficiency and carcass quality. To analyze the differential deposition of IMF and AF in chickens, gene expression profiles in the breast muscle (BM) and AF tissues of 18 animals were analyzed by differential expression anal. and weighted co-expression network anal. The results showed that IMF deposition in BM was associated with pyruvate and citric acid metabolism through GAPDH, LDHA, GPX1, GBE1, and other genes. In contrast, AF deposition was related to acetyl CoA and glycerol metabolism through FABP1, ELOVL6, SCD, ADIPOQ, and other genes. Carbohydrate metabolism plays an essential role in IMF deposition, and fatty acid and glycerol metabolism regulate AF deposition. Conclusion: This study elucidated the mol. mechanism governing IMF and AF deposition through crucial genes and signaling pathways and provided a theor. basis for producing high-quality broilers.

BMC Genomics published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Recommanded Product: Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Henderson, Luke published the artcileModelling the formation, growth and coagulation of soot in a combustion system using a 2-D population balance model, Category: catalysis-chemistry, the publication is Combustion and Flame (2022), 112303, database is CAplus.

A 2-D population balance model utilizing carbon mass and surface sites as internal variables was developed for soot formation during hydrocarbon decomposition reactions. The model provides particle properties such as composition and mean polyaromatic hydrocarbon size, enabling the incorporation of cyclization reactions, soot maturation, and a dynamic model of surface reactions. Accompanied by a reduced kinetic model for gas-phase species, this population balance model was then discretized using the fixed-pivot method, to provide predictions of the soot distribution as a function of position within a plug flow reactor. The model predictions of the particle size distribution functions resulting from high-temperature hydrocarbon pyrolysis within a PFTR system provide good comparison with exptl. measurements under a variety of conditions. In addition to this, by tracking the changes in particle composition occurring through cyclization reactions, the point of carbon particle maturity could be determined, allowing subsequent predictions of the size distributions of the primary particles comprising soot aggregates. Through comparison with TEM and SEM imaging, these primary particle distributions were found to be accurate for the exptl. conditions examined While the implementation of the second internal variable describing particle composition was not found to provide substantial improvements to the prediction of the overall aggregate distribution from existing models, the addnl. computational cost that accompanies addnl. variables is justified in applications where morphol. predictions of particle aggregates are of interest, in addition to their size distribution.

Combustion and Flame published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sheena Mary, Y. published the artcileUnderstanding reactivity of a triazole derivative and its interaction with graphene and doped/undoped-coronene-a DFT study, Recommanded Product: Coronene, the publication is Journal of Biomolecular Structure and Dynamics (2022), 40(5), 2316-2326, database is CAplus and MEDLINE.

In the present study, 4-[(E)-(2-chorobenzylidene)amino]-3-(2-chlorobenzyl)-1H-1,2,4-triazole-5(4H)-thione (CAC) was characterized by spectroscopic investigations. The complete vibrational assignments of frequencies based on PED anal. was determined by DFT through ¦ØB97X-D method with the level of 6-31g(d) basis and compared with exptl. values. Recently nanocluster based drug delivery systems have become the most skilful to study. Interaction mechanism of CAC over coronene (G), doped CAC-G-X (X = B/N/P) and with graphene were investigated. Variations in chem. descriptors are also noted to understand sensing property of CAC mol.-nanoclusters. The anal. of different properties demonstrates enhancement effect which makes it significant in detecting CAC in other products. Mol. electrostatic potential energy surface was employed to investigate the most reactive sites. Besides to gain better insight on structural features, HOMO-LUMO band gap energy and other chem. parameters was obtained. The anticancer activity of CAC against various inhibitors for different protein targets (4AT9, 6NE5, 5ZBQ, and 3A43) was studied using mol. docking.

Journal of Biomolecular Structure and Dynamics published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C6H12N2O, Recommanded Product: Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Augulis, Vaclovas published the artcileSupravital staining and fixation of brain and spinal cord by intravascular perfusion, Related Products of catalysis-chemistry, the publication is Stain Technology (1971), 46(4), 183-90, database is CAplus and MEDLINE.

Forty single and 13 combinations of dyes were tested for concomitant supravital staining and fixation of brain and spinal cord of rats, cats, and squirrel monkeys by intravascular perfusion in 3 steps: (1) 60 or 80 ml of physiol. saline containing 40 mg/100 ml of NaNO2 as a vasodilator; (2) 250 or 550 ml of stain-fixative solution consisting of either: A-2 parts of dye solution in a concentration from 0.001% to 0.05% dissolved in saline containing 40 mg/100 ml of NaNO2 and 1 part undiluted formalin; or B-2 parts of dye solution in a concentration from 0.001% to 0.05% dissolved in distilled water acidified with 1.5 ml of glacial HOAc/100 ml of water, and 1 part undiluted formalin; and (3) 100 or 150 ml of 6% dextrose in distilled water. Complete staining and fixation was accomplished in 53 min for rats and 41 min for cats and monkeys. Brains and spinal cord were frozen, sectioned, and the cut surfaces of the frozen tissue were photographed similar to the procedure described by Gasteiger, et al. (1969).

Stain Technology published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wu, Shuangshuang published the artcileAggregation-induced emissive carbon dots gels for octopus-inspired shape/color synergistically adjustable actuators for soft robots, Related Products of catalysis-chemistry, the publication is Angewandte Chemie, International Edition (2021), 60(40), 21890-21898, database is CAplus and MEDLINE.

Some living organisms such as the octopus have fantastic abilities to simultaneously swim away and alter body color/morphol. for disguise and self-protection, especially when there is a threat perception. However, it is still quite challenging to construct artificial soft actuators with octopus-like synergistic shape/color change and directional locomotion behaviors, but such systems could enhance the functions of soft robotics dramatically. Herein, we proposed to utilize unique hydrophobic carbon dots (CDs) with rotatable surface groups to construct the aggregation-induced emission (AIE) active glycol CDs polymer gel, which could be further employed to be interfacially bonded to an elastomer to produce anisotropic bilayer soft actuator. When putting the actuator on a water surface, glycol spontaneously diffused out from the gel layer to allow water intake, resulting in a color change from a blue dispersion fluorescence to red AIE and a shape deformation, as well as a large surface tension gradient that can promote its autonomous locomotion. Based on these findings, artificial soft swimming robots with octopus-like synergistic shape/color change and directional swimming motion were demonstrated. This study provides an elegant strategy to develop advanced multi-functional bio-inspired intelligent soft robotics.

Angewandte Chemie, International Edition published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C10H10CoF6P, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia