Tag: M.W=300-350

Ma, Yuan-Yuan published the artcilePrediction of freestanding semiconducting bilayer borophenes, Related Products of catalysis-chemistry, the publication is Nano Research (2022), 15(6), 5752-5757, database is CAplus.

Supported bilayer ¦Á-borophene (BL-¦Á borophene) on Ag(111) substrate has been synthesized in recent experiments Based on the exptl. observed quasi-planar C_6v B₃₆ (1), its monolayer assembly ¦Á+-borophene B11 (P6/mmm) (2), and extensive global min. searches augmented with d. functional theory calculations, we predict herein freestanding BL-¦Á+ borophenes B22 (Cmmm) (3) and B22 (C2/m) (4) which, as the most stable BL borophenes reported to date, are composed of interwoven boron triple chains as boron analogs of monolayer graphene (5) consisting of interwoven carbon single chains. The nearly degenerate eclipsed B22 (3) and staggered B22 (4) with the hexagonal hole d. of ¦Ç = 1/12 and interlayer bonding d. of u = 1/4 appear to be two-dimensional semiconductors with the indirect band gaps of 0.952 and 1.144 eV, resp. Detailed bonding analyses reveal one delocalized 12c-2e ¦Ð bond over each hexagonal hole in both the B22 (3) and B22 (4), similar to the situation in monolayer graphene which contains one delocalized 6c-2e ¦Ð bond over each C6 hexagon. Furthermore, these BL-¦Á+ borophenes appear to remain highly stable on Ag(111) substrate, presenting the possibility to form supported BL-¦Á+ borophenes.

Nano Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lin, Nai-Pin published the artcileSynthesis and characterization of phenylboronic acid-modified insulin with glucose-dependent solubility, Application In Synthesis of 71989-31-6, the publication is Frontiers in Chemistry (Lausanne, Switzerland) (2022), 859133, database is CAplus and MEDLINE.

Glucose-responsive insulin represents a promising approach to regulate blood glucose levels. We previously showed that attaching two fluorophenylboronic acid (FPBA) residues to the C-terminal B chain of insulin glargine led to glucose-dependent solubility Herein, we demonstrated that relocating FPBA from B chain to A chain increased the baseline solubility without affecting its potency. Furthermore, increasing the number of FPBA groups led to increased glucose-dependent solubility

Frontiers in Chemistry (Lausanne, Switzerland) published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Application In Synthesis of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tan, Bochuan published the artcileExperimental and theoretical studies on the inhibition properties of three diphenyl disulfide derivatives on copper corrosion in acid medium, Category: catalysis-chemistry, the publication is Journal of Molecular Liquids (2020), 111975, database is CAplus.

2,2′-Dithiosalicylic acid (DSA), 2-aminophenyl disulfide (APD) and 2,2-dibenzamidodiphenyl disulfide (DPD) were determined for corrosion inhibition of Cu in H₂SO₄ media by electrochem. tests, surface morphol. anal., quantum chem. calculations and mol. dynamics simulations. The results of polarization curves showed that DSA, APD and DPD reveal good anti-corrosion capacity. They can simultaneously inhibit the cathodic and anodic reactions of copper. Therefore, they belong to the mixed-type corrosion inhibitors. Impedance spectroscopy results showed that when DSA, APD and DPD adsorption on the surface of Cu, the charge transfer resistance increases significantly and typical capacitance behavior produced, which indicates that the formed inhibitor film is very dense and ordered. In addition, the adsorption of corrosion inhibitors on the Cu surface is conforming to Langmuir monolayer adsorption. The exptl. results obtained by surface topog. anal. are consistent with the results of electrochem. experiments Their corrosion inhibition ability is DSA < APD < DPD. Theor. calculations further explore the relationship between corrosion inhibition performance and their mol. configurations.

Journal of Molecular Liquids published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C15H24S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yang, Huan published the artcileDithiosulfindene Adsorption and Reaction on Gold Nanoparticles in Water, Product Details of C14H10O4S2, the publication is Journal of Physical Chemistry C (2020), 124(1), 686-692, database is CAplus.

Dithiosulfindene (DTS) is a model mol. for dithiolethiones, a class of biomedically important sulfur-rich compounds with the general formula R₁-S-S-C( = S)-R₂. Reported herein is a combined exptl. and computational study of DTS interactions with plasmonic gold nanoparticles (AuNPs) in water. DTS adsorptions and reactions on AuNPs were investigated using a combination of UV-vis, Raman, and surface-enhanced Raman spectroscopy (SERS) methods. The saturation packing d. of DTS on AuNPs is 596 pmol/cm², and its structure and conformation on AuNP surfaces depend critically on its packing d. NaOH reacts with DTS both in water and on AuNPs, converting DTS into thiosalicylic acid (TSA). TSA produced by NaOH reaction with DTS preadsorbed onto AuNPs partitions between remaining on the AuNP surfaces and being released to the supernatant of the reaction solution UV-vis measurements revealed that NaOH reaction with DTS in solution and on AuNPs both follow first-order kinetics with a rate constant of 0.71 and 2.94 h^-1, resp. In contrast, SERS is highly effective in detecting the completeness of the reactions and informative for identifying the reaction products, but is unreliable for either in situ monitoring of the NaOH reaction with DTS adsorbed on aggregated AuNPs or ex situ detecting of solution composition change from NaOH reaction with DTS in solution The insights derived from this study should be important for developing an in-depth understanding of dithiolethione adsorptions and reactivities on AuNPs. This work also highlights the advantages and limitations of SERS for both in situ and ex situ monitoring of chem. reactions in solutions

Journal of Physical Chemistry C published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C18H24N6O6S4, Product Details of C14H10O4S2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chen, Yaoxia published the artcileSupramolecular nanofibers with superior anti-angiogenesis and antitumor properties by enzyme-instructed self-assembly (EISA), Product Details of C20H19NO4, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2021), 130531, database is CAplus.

Currently, combination therapy has become a popular research topic in cancer therapy. However, the outcome of the current combination therapy strategy does not satisfy the demand for clin. applications because of factors such as their overlapping toxicities, poor drug payload, and inevitable therapy resistance. Supramol. self-assembly of peptides holds great potential for solving relevant problems and achieving superior therapeutic effects. In this study, we aimed to propose supramol. self-assemblies based on a combination therapy strategy, consisting of a heptapeptide A7R for the inhibition of angiogenesis, the chemotherapeutic drug HCPT for treating numerous tumors with high efficacy, and an efficient self-assembling mol. FFY to improve drug loading and cell permeability. We regulated the secondary structure of nanomaterials by optimizing the pathways of self-assembly and significantly improved the affinity of A7R peptide to NRP-1. Endothelial tube formation in Matrigel and a tumor mouse model (in vivo) were then performed to demonstrate the superior antitumor effects of our supramol. self-assemblies both in vitro and in vivo. In summary, this work not only provides a promising platform for the development of effective combination therapy, but also offers a useful strategy to prepare self-assembled nanomaterials with optimized performance.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Product Details of C20H19NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Jinghong published the artcileChar Structure and Charring Mechanism of Phosphazene-Based Epoxy Resin during Combustion, Synthetic Route of 191-07-1, the publication is Polymer Degradation and Stability (2022), 109927, database is CAplus.

The char structure and charring mechanism were important factors in determining the flame retardancy of the polymer. However, relevant research on phosphazene-based polymers, which have excellent fire retardancy, was limited. In our previous work, a phosphazene-based epoxy resin (EHEP-D230) was obtained with a honeycomb-like structure char after combustion. Herein, we further investigated gaseous phase degradation products of the resin through TGA-FTIR, while the condensed phase degradation products, the char, were studied using a variety of characterization techniques, including EDS mapping, FTIR, XPS, solid ³¹P-NMR and Raman. The study shows that nitrogen products of phosphazene were found in both the gaseous (e.g. NH₃) and condensed phases (e.g. pyridine, pyrrole, and quaternary-nitrogen structure), whereas phosphorus products (e.g. phosphoric acid-like structures) were discovered in the condensed phase with an uneven distribution. This finding was confirmed by the degradation of the other two phosphazene epoxy resins (HGETP-D230 and HGETP-MNA). Addnl., the distance between two defects in the EHEP-D230 char (doped carbon structures) might range between 5.6 ? and 17.2 ?, indicating that the char of EHEP-D230 is highly disordered. Subsequently, we compared our research results with those of previous studies on phosphazene degradation in the field of epoxy, and offered a global chem. structure of EHEP-D230’s char. Furthermore, a charring mechanism involving the aggregating-pressing process of phosphorous was proposed.

Polymer Degradation and Stability published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Synthetic Route of 191-07-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Libalova, Helena published the artcileTranscription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol blend, Product Details of C24H12, the publication is Mutation Research, Genetic Toxicology and Environmental Mutagenesis (2021), 503414, database is CAplus and MEDLINE.

Emissions from road traffic are among the major contributors to air pollution worldwide and represent a serious environmental health risk. Although traffic-related pollution has been most commonly associated with diesel engines, increasing evidence suggests that gasoline engines also produce a considerable amount of potentially hazardous particulate matter (PM). The primary objective of this study was to compare the intrinsic toxic properties of the organic components of PM, generated by a conventional gasoline engine fueled with neat gasoline (E0), or gasoline-ethanol blend (15% ethanol, volume/volume, E15). Our results showed that while E15 has produced, compared to gasoline and per kg of fuel, comparable particle mass (¦Ìg PM/kg fuel) and slightly more particles by number, the organic extract from the particulate matter produced by E15 contained a larger amount of harmful polycyclic aromatic hydrocarbons (PAHs), as determined by the chem. anal. To examine the toxicity, we monitored genome-wide gene expression changes in human lung BEAS-2B cells, exposed for 4 h and 24 h to a subtoxic dose of each PM extract After 4 h exposure, numerous dysregulated genes and processes such as oxidative stress, lipid and steroid metabolism, PPAR¦Á signaling and immune response, were found to be common for both extract treatments. On the other hand, 24 h exposure resulted in more distinctive gene expression patterns. Although we identified several common modulated processes indicating the metabolism of PAHs and activation of aryl hydrocarbon receptor (AhR), E15 specifically dysregulated a variety of other genes and pathways related to cancer promotion and progression. Overall, our findings suggest that the ethanol addition to gasoline changed the intrinsic properties of PM emissions and increased the PAH content in PM organic extract, thus contributing to a more extensive toxic response particularly after 24 h exposure in BEAS-2B cells.

Mutation Research, Genetic Toxicology and Environmental Mutagenesis published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Product Details of C24H12.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kang, Ziyao published the artcileTransferrin receptor targeting segment T7 containing peptide gene delivery vectors for efficient transfection of brain tumor cells, Safety of Fmoc-Pro-OH, the publication is Drug Delivery (2022), 29(1), 2375-2385, database is CAplus and MEDLINE.

Successful gene therapy for brain tumors are often limited by two important factors, the existence of blood brain barrier (BBB) and inefficient transfection of brain tumor cells. In this study, we designed a series of peptide-based gene delivery vectors decorated with T7 segment for binding the transferrin (Tf) receptors which were highly expressed on brain tumor cells, and evaluated their ability of gene delivery. The physicochem. properties of peptide vectors or peptide/DNA complexes were studied as well. The in vitro transfection efficiency was investigated in normal and glioma cell lines. Among these complexes, PT-02/DNA complexes showed the highest transfection efficiency in glioma cells and low cytotoxicity in normal cell lines, and it could transport DNA across the BBB model in vitro. Furthermore, PT-02/DNA could deliver pIRES2-EGFP into the brain site of zebrafish in vivo. The designed peptide vectors offered a promising way for glioma gene therapy.

Drug Delivery published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Safety of Fmoc-Pro-OH.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bai, Xiang-Ru published the artcileEnvironmentally Safe Mercury(II) Ions Aided Zero-Background and Ultrasensitive SERS Detection of Dipicolinic Acid, COA of Formula: C18H15N3O3, the publication is Analytical Chemistry (Washington, DC, United States) (2017), 89(19), 10335-10342, database is CAplus and MEDLINE.

Field, reliable, and ultrasensitive detection of dipicolinic acid (DPA), a general biomarker of bacterial spores and especially Bacillus anthracis, is highly desirable but still challenging in the current biometric security emergency response system. Herein the authors report an environmentally safe mercury(II) ions-mediated and competitive coordination interaction based approach for rationally designed surface-enhanced Raman scattering (SERS)-active gold nanoparticles (AuNPs), enabling rapid, ultrasensitive and zero-background detection of DPA without the pretreatment of samples. By competitiveness, these papain-capped gold nanoparticles (P-AuNPs) are induced to undergo controllable aggregation upon the addition of Hg²⁺ ions and DPA with a concentration range (1 nM?8 ¦ÌM), which correspondingly cause quant. changes of SERS intensity of cresyl violet acetate (CVa) conjugated AuNPs. The decreased Raman intensity obtained by subtracting two cases of additives that contain only Hg²⁺ and the mixture of Hg²⁺ and DPA is proportional to the concentration of DPA over a range of 1 nM?8 ¦ÌM (R² = 0.9824), with by far the lowest limit of detection (LOD) of 67.25 pM (0.01 ppb, S/N = 3:1). Of particular significance, mercury(II) ions actually play two roles in the process of measurements: a mediator for two designed competitive ligands (DPA and papain) and also a scavenger for the possibly blended ligands due to the different interaction time between DPA and the interferent with Hg²⁺ ions, which guarantees the interference-free detection of DPA even under real conditions.

Analytical Chemistry (Washington, DC, United States) published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, COA of Formula: C18H15N3O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chen, Yu-Ping published the artcileParticle size-resolved emission characteristics of complex polycyclic aromatic hydrocarbon (PAH) mixtures from various combustion sources, Safety of Coronene, the publication is Environmental Research (2022), 214(S), 113840, database is CAplus and MEDLINE.

Combustion of domestic solid fuels is a significant source of polycyclic aromatic hydrocarbons (PAHs). Some oxygenated PAHs (o-PAHs) and PAHs with mol. weight of 302 (MW302 PAHs) are more toxic than the traditional 16 priority PAHs, whereas their emissions were much less elucidated. This study characterized the size-dependent emissions of parent PAHs (p-PAHs), o-PAHs, and MW302 PAHs from various combustion sources. The estimated emission factors (eEFs) from biomass burning sources were highest for most of the PAHs (391-8928¦Ìg/kg), much higher than that of anthracite coal combustion (43.0-145¦Ìg/kg), both which were operated in an indoor stove. Cigarette smoking had a high eEF of o-PAHs (240 ng/g). MW302 PAHs were not found in the emissions of smoking, cooking, and vehicular exhausts. Particle-size distributions of PAHs were compound- and source-dependent, and the tendency to associate with smaller particles was observed especially in biomass burning and cigarette smoking sources. Furthermore, the inter-source differences in PAH eEFs were associated with their dominance in fine particles. PAH composition profiles also varied with the particle size, showing increasing contributions of large-mol. PAHs with decreasing sizes in most cases. The size distributions of p-PAHs are much more significantly dependent on their n-octanol/air partition coefficients and vapor pressures than those of o-PAHs, suggesting differences in mechanisms governing their distributions. Several mol. diagnostic ratios (MDRs), including two based on MW302 PAHs, specific to these combustion scenarios were identified. However, the MDRs within some sources are also strongly size-dependent, providing a new explanation for the uncertainty in their application for source identification of PAHs. This work also highlights the necessity for understanding the size-resolved atm. behaviors and fate of PAHs after their emission.

Environmental Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Safety of Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia