Tag: M.W=300-350

Nascimento, Madson M. published the artcileDetermination of 3-nitrobenzanthrone, its metabolites, and 41 polycyclic aromatic compounds (16 PAHs, 19 nitro-PAHs, and 6 oxy-PAHs) in ascidians (Phallusia nigra), SDS of cas: 191-07-1, the publication is Microchemical Journal (2022), 107081, database is CAplus.

This work demonstrates an effective solid-liquid extraction procedure, in combination with a microscale dispersive solid-phase extraction cleanup, for the determination of 44 polycyclic aromatic compounds, including the potent mutagenic compound 3-nitrobenzathrone and its metabolites 3-aminobenzanthrone and 3-acethyl-aminobenzanthrone, in Phallusia nigra. A new customized device was constructed using borosilicate glass to perform the ultrasound-assisted extraction of the compounds The dispersive solid-phase extraction cleanup was carried out in a microscale device filter and optimized though multivariate statistical tools. The optimum conditions were determined as 93 mg of activated alumina/silica gel (1:1, weight/weight) and vortex-assisted agitation for 3.50 min. The limit of detection ranged from 5.47 to 9.89 ng g-1, 7.27 to 1,524 ng g-1, and 42.7 to 108 ng g-1 for PAHs, oxy-PAHs, and nitro-PAHs, resp. The ANOVA test (p < 0.05) indicated no evidence of lack-of-fit for the matrix-matched anal. curves, with R2 > 0.990. The recoveries on the DORM-3 reference standard material ranged from 75.3% to 120%, 77.6% to 117%, and 70% to 124% for PAHs, oxy-PAHs, and nitro-PAHs, resp. The developed procedure was applied to nine ascidians samples. PAHs, oxy-PAHs, and nitro-PAHs were detected in the samples at concentrations ranging from 5.02 to 489 ng g-1 dw, 28.8 to 6,587 ng g-1, and 32.3 to 1,635 ng g-1, resp. Thus, the proposed procedure was comprehensive, precise, accurate, and suitable for the determination of these compounds in ascidians samples.

Microchemical Journal published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, SDS of cas: 191-07-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

De, Soumya Kanti published the artcileLipid phase dependent distinct emission behaviour of hydrophobic carbon dots: C-dot based membrane probes, Recommanded Product: 2,2′-Dithiodibenzoic acid, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(72), 9080-9083, database is CAplus and MEDLINE.

We observe a unique distinct emission behavior of hydrophobic carbon dots (H-CDs) embedded within the ordered and the disordered phase of a lipid membrane. The H-CDs exhibit blue emission in the disordered phase, however, they exhibit an intense red emission in the ordered phase of the lipid bilayer. The H-CDs have the potential ability to probe membrane dynamics like previously reported organic dyes. To the best of our knowledge, this is the first report of a CD-based membrane probe.

Chemical Communications (Cambridge, United Kingdom) published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Recommanded Product: 2,2′-Dithiodibenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ueda, Atsushi published the artcileE-Selective ring-closing metathesis in ¦Á-helical stapled peptides using carbocyclic ¦Á,¦Á-disubstituted ¦Á-amino acids, Related Products of catalysis-chemistry, the publication is Organic Letters (2022), 24(4), 1049-1054, database is CAplus and MEDLINE.

We present an E-selective ring-closing metathesis reaction in ¦Á-helical stapled peptides at positions i and i + 4. The use of two chiral carbocyclic ¦Á,¦Á-disubstituted ¦Á-amino acids, (1S,3S)-Ac₅c^3OAll and (1R,3S)-Ac₅c^3OAll, provides a high E-selectivity of a ¡Ü59:1 E:Z ratio, while mixtures with E:Z ratios of 2.1-0.5:1 were produced with standard acyclic (S)-(4-pentenyl)alanine amino acids. A stapled octapeptide composed of (1S,3S)- and (1R,3S)-Ac₅c^3OAll amino acids showed a right-handed ¦Á-helical crystal structure.

Organic Letters published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C3H5BN2O2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Di Mauro, Chiara published the artcileSustainable Series of New Epoxidized Vegetable Oil-Based Thermosets with Chemical Recycling Properties, Computed Properties of 119-80-2, the publication is Biomacromolecules (2020), 21(9), 3923-3935, database is CAplus and MEDLINE.

This work reports for the first time the copolymerization studies of 11 newly synthesized epoxidized vegetable oils (EVOs) that reacted with a disulfide-based aromatic dicarboxylic acid (DCA) to produce thermoset materials with recyclability properties. These new EVOs’ reactivity and properties were compared with those of the two com. references: epoxidized linseed oil (ELO) and epoxidized soybean oil (ESO). The structure-reactivity correlation is proposed by differential scanning calorimetry (DSC) anal., corroborating the epoxy content of EVO monomers, the initiator effect, the copolymerization reaction enthalpy, and the temperature range. The thermomech. properties of the obtained thermosets were evaluated and discussed in correlation with the structure and reactivity of monomers by dynamic mech. anal. (DMA), tensile testing, and thermogravimetric anal. (TGA). It has been found that the higher the EVO functionality, the higher is the reactivity, crosslinking d., and final performances, with tan ¦Ä values ranging from 34 to 111¡ãC. This study investigates the chem. recycling and the solvent resistance of these vitrimer-like materials that have a high bio-based carbon content, from 58 to 79%, with potential application in coating or composite materials in the automotive sector.

Biomacromolecules published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Computed Properties of 119-80-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Di Mauro, Chiara published the artcileRecyclable, Repairable, and Reshapable (3R) Thermoset Materials with Shape Memory Properties from Bio-Based Epoxidized Vegetable Oils, Application In Synthesis of 119-80-2, the publication is ACS Applied Bio Materials (2020), 3(11), 8094-8104, database is CAplus and MEDLINE.

The preparation of thermosets based on epoxidized vegetable oils (EVOs) involved a peculiar attention in recent years; however, most of them cannot be recycled once crosslinked. In the present work, epoxy thermosetting resins like-vitrimers with dynamic disulfide covalent bonds were prepared by copolymerizing twelve EVOs with 2,2′-dithiodibenzoic acid, as hardener. Here, we show for the first time the reprocessability, repairability, and recyclability properties of EVOs thermosets. The 3R abilities were evaluated in correlation with the EVO epoxy contents, which influence the final thermo-mech. properties of the recycled material. The virgin vs. recycled materials’ comparison was studied by FT-IR, DSC, TGA, and DMA, also comparing their swelling ability and high gel content. The study investigates, in addition, the excellent shape memory properties of the reprocessed EVOs/disulfide materials.

ACS Applied Bio Materials published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Application In Synthesis of 119-80-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Chenxuan published the artcileInhibition of ¦¤-6 desaturase reduces fatty acid re-esterification in 3T3-L1 adipocytes independent of changes in n3-PUFA cellular content, Product Details of C22H32O2, the publication is Biochimica et Biophysica Acta, Molecular and Cell Biology of Lipids (2022), 1867(7), 159160, database is CAplus and MEDLINE.

¦¤-6 Desaturase (D6D) is a key enzyme in the synthesis of long-chain polyunsaturated fatty acids (LC-PUFA). Evidence suggests that reduced D6D activity not only disrupts LC-PUFA production, but also impacts whole body lipid handling and body weight; however, the mechanisms remain largely unexplored. Therefore, we investigated the effect of D6D inhibition on the regulation of lipid accumulation in 3T3-L1 adipocytes with and without changes in n-3 PUFA content. 3T3-L1 cells were treated with a D6D inhibitor (SC-26196) in the presence or absence of ¦Á-linolenic acid (ALA) throughout differentiation. We found that D6D inhibition blocked the conversion of ALA to eicosapentaenoic acid (EPA) and docosapentaenoic acid (DPAn-3) when ALA was supplemented, while no changes in n-3 PUFA content were observed in cells treated with the D6D inhibitor alone. D6D inhibited cells had reduced triacylglycerol (TAG) accumulation despite an EPA/DPA deficiency. In addition, analyses of cellular protein markers, as well as non-esterified fatty acids and glycerol release in medium, suggested an increase in lipolysis and a decrease in fatty acid re-esterification in D6D-inhibited cells, independent of n-3 PUFA changes. To provide further evidence, we treated cells with the D6D inhibitor in the presence or absence of EPA and compared them with ALA-treated cells. Although EPA further reduced TAG content, the reduced markers of fatty acid re-esterification were not affected by ALA or EPA. Collectively, this study provides new insight showing that D6D inhibition reduces TAG accumulation and fatty acid re-esterification in adipocytes independent of changes in n-3 PUFA cellular content.

Biochimica et Biophysica Acta, Molecular and Cell Biology of Lipids published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C15H12O8, Product Details of C22H32O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bisht, Babita published the artcileQuick Access to High-Purity Peptide Drugs Bradykinin, Leuprolide Analogue, 2(PZ-128), and Rapastinel with Minimal Reagents, Application In Synthesis of 71989-31-6, the publication is Journal of Organic Chemistry (2021), 86(24), 17667-17672, database is CAplus and MEDLINE.

Peptide drugs bradykinin, a leuprolide analog, 2(PZ-128), and rapastinel are synthesized in 56-77% yield using heating-assisted liquid-phase peptide synthesis on a soluble polynorbornene support. These drugs of com. utility and complex structures are obtained in 2-5.5 h with no epimerization and >95% purity using only 1.2 equiv of amino acids and coupling reagents. The peptide yield and purity are comparable or superior to the reported methods.

Journal of Organic Chemistry published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Application In Synthesis of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kurnia, Dessy Yulyani published the artcileTotal synthesis of xylapeptide B [Cyclo-( L-Leu-L-Pro-N-Me-Phe-L-Val-D-Ala )], Product Details of C20H19NO4, the publication is Journal of Heterocyclic Chemistry (2022), 59(1), 131-136, database is CAplus.

Xylapeptide B is a cyclopentapeptide isolated from Xylaria sp. derived from the Chinese medicinal plant Sophora tonkinensis. Xylapeptide B was successfully synthesized by a combination of solid- and solution-phase, using the Fmoc (Fmoc = 9-fluorenylmethoxycarbonyl) strategy, and 2-chlorotrityl chloride resin. The coupling reagent used is a combination of HBTU/HOBt to assist in the formation of amide bonds. D-Ala was chosen as the C-terminal because it has a small residue and can facilitate the cyclization process. Linear peptide was cleaved from the resin using a dilute acid concentration of 20% TFA in DCM because the peptide has no protecting group at the side chain. Crude linear peptide was purified by semi-preparative RP-HPLC using 0%-100% ACN eluent for 35 min and obtained a pure mass of 22.4 mg (18.83%). Cyclization was carried out in solution phase using HBTU (3 equivalent) and DIPEA (1% volume/volume) in diluted concentration (1.25 mM) for 72 h at room temperature The cyclization stage was monitored by thin-layer chromatog. (TLC). Crude xylapeptide B was purified by semi-preparative RP-HPLC using 30%-80% ACN eluent for 40 min, to result in 6 mg (8.91%) of the desired xylapeptide B. All synthesized products were characterized by HR-TOFMS, ¹H-, and ¹³C-NMR.

Journal of Heterocyclic Chemistry published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Product Details of C20H19NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gholamalian, Reihaneh published the artcileHepatic fatty acids profile, oxidative stability and egg quality traits ameliorated by supplementation of alternative lipid sources and milk thistle meal, SDS of cas: 6217-54-5, the publication is Journal of Animal Physiology and Animal Nutrition (2022), 106(4), 860-871, database is CAplus and MEDLINE.

This study assessed the effects of different levels of milk thistle (Silybum marianum) meal (MTM) on egg quality traits, oxidative stability, blood biochem. parameters and liver health indexes in laying hens receiving diets supplemented with lipid from different sources. For this purpose, Leghorn laying hens (Hy-Line W-36) were randomly assigned to 12 exptl. treatments with eight replicates of five birds each. Dietary treatments consisted of four dietary fat sources (fish oil, sunflower oil, poultry oil and fat powder, each with different fatty acid profiles) and three levels of MTM (0.0, 15 and 30 g/kg) offered through 10 days of adaptation and 70 days of main recording. Results showed that dietary inclusion of polyunsaturated fatty acids, including fish or sunflower oils, reduced serum cholesterol content but increased blood malondialdehyde (MDA) concentration (p < 0.05). While fish oil improved the yolk color index and Haugh unit (p < 0.05), it decreased yolk cholesterol concentration (p < 0.01). The highest hepatic glycogen content and tissue integrity as well as the lowest liver lipid percentage and MDA content were observed in birds fed diets supplemented with poultry oil. On the other hand, feeding 30 g/kg of MTM reduced not only hepatic lipid percentage but also aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities (p < 0.01), while it improved eggshell strength and thickness (p < 0.05). Supplementation of fat powder enhanced hepatic C16:0 content, while addition of poultry, sunflower or fish oil increased C18:1, C18:2 or C20:5 concentrations resp. (p < 0.01); nonetheless, feeding the highest level of MTM reduced hepatic ¦²SFA but increased ¦²n-3 fatty acids (p < 0.01). The interaction effects indicated that fish or sunflower oil supplementation increased the MTM level required to reduce not only serum or egg cholesterol concentrations (p < 0.05) but also blood or hepatic MDA content (p < 0.01). It was concluded that fish oil and MTM (30 g/kg) supplements might improve internal egg quality traits and eggshell quality resp. The hepatic fatty acid profile was also found strongly correlated with dietary fatty acids. Finally, the best hepatic health indexes and the highest oxidative stability were achieved when the birds were fed diets supplemented with poultry oil and 30 g/kg of MTM.

Journal of Animal Physiology and Animal Nutrition published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, SDS of cas: 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shan, Shijie published the artcileSelf-Healing, Reprocessable, and Degradable Bio-Based Epoxy Elastomer Bearing Aromatic Disulfide Bonds and Its Application in Strain Sensors, Application In Synthesis of 119-80-2, the publication is ACS Applied Polymer Materials (2021), 3(10), 5115-5124, database is CAplus.

A dicarboxylic acids functional aromatic disulfide (DTSA) and a dimer aliphatic acid (DAA) were used to crosslink epoxidized soybean oil (ESO) to obtain a bio-based epoxy elastomer with comprehensive properties of toughness and stretchability. This work addresses some urgent needs for epoxy networks, such as recyclability, degradability, and mech. properties. Ratios of permanent and dynamic crosslinks were tuned to yield epoxy elastomers with various characteristics. The bio-based epoxy elastomer in this work took advantages of dynamic aromatic disulfide bonds which can rapidly exchange even at room temperature without external stimuli. Therefore, the epoxy elastomer reported here presented almost quant. self-healing efficiency and high recovery in terms of mech. properties after being reprocessed for many times. Besides, incorporation of permanent chem. crosslinks with DAA caused low hysteresis, which made them suitable for fabricating sensitive and durable strain sensor against cyclic strain.

ACS Applied Polymer Materials published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C15H21BO3, Application In Synthesis of 119-80-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia