Category: 10517-44-9

Schwarzenbach, G. published the artcileThe calculation of intramolecular atomic separation from the dissociation constants of dibasic acids. II. The acidity of some dicarboxylic acids and polymethylene-diammonium ions in water-alcohol mixtures, Name: Propane-1,3-diamine dihydrochloride, the publication is Helvetica Chimica Acta (1933), 522-8, database is CAplus.

cf. C. A. 27, 1556. From e. m. f. determinations in 0-80% aqueous EtOH at 20¡ã are obtained the 1st and 2nd dissociation constants of the acids (CH₂)_n-2(CO₂H)₂ and (CH₂)_n (NH₃⁺)2 where n = 2, 3, 4, 5, 8. For each acid, except oxalic, the relation ?D^x = constant holds (? = work of removing the 2nd proton, D = dielec. constant of the solution, x = constant).

Helvetica Chimica Acta published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C12H13NO3, Name: Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sakurai, Masao published the artcileApparent molal volumes of some organic electrolytes in a dilute aqueous solution at 5, 25, and 45.deg., Category: catalysis-chemistry, the publication is Bulletin of the Chemical Society of Japan (1973), 46(6), 1596-602, database is CAplus.

The apparent molal volumes, ?v, of 5 series of homologous organic salts of the H(CH2)n-COONa (n = 0-6), (CH2)n(COONa)2 (n = 0, 2, 3, 4, 6, 8), H-(CH2)nNH3Cl (n = 0, 2, 6), (CH2)n(NH3Cl)2 (n = 2, 3, 6), and H(CH2)nSO3Na (n = 1,2) types in a dilute aqueous solution were measured by means of a float method as a function of the concentration and the temperature The coefficients of the deviation of ?v from the Debye-Hueckel limiting law, bv, are neg. for most organic electrolytes. The large pos. bv values observed for the Na oxalate and Na succinate solutions at 5¡ã were attributed to ion-pair formation. The partial molal expansibility of organic ions were evaluated and interpreted on the basis of the multilayer hydration model. The estimation of volume increments per CH2 group suggests that the influences of ammonium ions on the hydrophobic hydration around CH2 groups differ significantly from those of carboxylate ions. The volume change accompanying the substitution of a terminal H atom with an ionic group was calculated, and discussed in connection with the overlapping effect of electrostriction in bolaform electrolytes.

Bulletin of the Chemical Society of Japan published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Saito, Shuji published the artcilePrecipitation of nonionic surfactants with polymeric acids – effect of organic cations, Category: catalysis-chemistry, the publication is Tenside Detergents (1980), 17(2), 84-5, database is CAplus.

Poly(acrylic acid) [9003-01-4] forms a complex with C₈H₁₇C₆H₄O(CH₂CH₂O)_nH [9036-19-5] (average n = 9.2), and the complex is precipitated from aqueous solution by the addition of H(CH₂)_nNH₂.HCl (I) (n = 1, 4, 6, 8, or 12) or H₂N(CH₂)_nNH₂.2HCl (II) (n = 3, 4, 6, or 8) to the solution At high concentrations of the amine salt, the precipitate is redispersed. The I are more effective than the II for precipitating the complex, and the precipitation and redispersion occur at lower salt concentrations with increasing alkyl chain length of the amines.

Tenside Detergents published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Raisfeld, Ilene H. published the artcileRole of terminal substituents in the pulmonary toxicity of bleomycins, Quality Control of 10517-44-9, the publication is Toxicology and Applied Pharmacology (1981), 57(3), 355-66, database is CAplus and MEDLINE.

Amines with structures identical to the chem. substituents X linked to the bithiazole rings of various bleomycins (I) were studied for their pulmonary toxicity in mice. Thus, intratracheally administered putrescine-2HCl [333-93-7], spermidine-3HCl [334-50-9], spermine-4HCl [306-67-2], histamine-HCl [56-92-8], 1,3-diaminopropane-HCl [10517-44-9], and agmatine sulfate [2482-00-0] produced dose-related lesions of pulmonary fibrosis and metaplasia indistinguishable from lesions produced by intact bleomycins. The high pulmonary toxicity of bleomycin A5 [11116-32-8] relative to bleomycin B2 [9060-10-0] corresponded to the changes produced by their resp. spermidine and agmatine substituents. An important role is suggested for the terminal substituent in bleomycin-induced lung injury.

Toxicology and Applied Pharmacology published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Quality Control of 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lofberg, R. T. published the artcileGas-chromatographic analysis of aminothiol radioprotective compounds, Computed Properties of 10517-44-9, the publication is Analytical Letters (1971), 4(2), 77-86, database is CAplus.

A gas chromatog. method is described for aminothiols and disulfides. This method is based upon the formation of the trimethylsilyl derivatives and their separation by gas chromatog. The kinetics of the derivative formation were investigated. A synthetic method for C4 to C6 aminothiols is given.

Analytical Letters published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Computed Properties of 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kost, A. N. published the artcileAcrylonitrile as a starting material for synthesis of amino nitriles and polyamines, SDS of cas: 10517-44-9, the publication is Uchenye Zapiski Moskov. Gosudarst. Univ. im. M. V. Lomonosova (1950), 39-97, database is CAplus.

cf. C.A. 41, 1609h; 42, 3722g. Dissertation at the University (1946) with complete exptl. details and bibliography of 169 references. A laboratory preparation of CH₂:CHCN (I) was developed as follows. To a hot saturated solution of 100 g. SnCl₂ was added 30 g. Zn dust with stirring and, after completion of reaction, the mixture was allowed to stand 2 hrs., decanted, washed with 10% AcOH, let stand overnight with 60 ml. 80-90% AcOH, filtered, washed with H₂O until neutral, and washed with EtOH and Et₂O, giving 30-35 g. Sn dust. All traces of Zn must be removed for good results with this catalyst. Heating 50 g. HOCH₂CH₂CN with 5 g. of the above Sn dust in a distillation apparatus with chilled receiver so that vapor temperature is below 110¡ã yields a 2-layer distillate; the upper layer after drying with CaCl₂ yields up to 90% I. If com. ethylene oxide is used in the preparation of the cyanohydrin, the product may be contaminated with MeCH:CHCN, H₂O, and NH₃; it is purified by 5-10 min. treatment with P₂O₅ and distillation (b₇₅₈ 78¡ã). Refluxing the cyanohydrin with silica gel, activated C, MgSO₄, Fe oxides, pieces of sheet Fe, Al foil, and Al₂O₃ gave but 0-30% yields of I. Passage of the cyanohydrin over Al₂O₃ at 200-20¡ã gave but 18-20% I. To 950 ml. aqueous NH₄OH (saturated in the cold) was added 95 g. I dropwise with cooling over 2 hrs. so that the mixture remained homogeneous; after 30 min. at room temperature, distillation gave 30% H₂NCH₂CH₂CN, b₁₄ 77-8¡ã, b₂₃ 89¡ã, n_D²⁰ 1.4390, d₂₀ 0.9584, which polymerized in several days in a sealed ampul even in darkness. Distillation of the higher-boiling residue gave 47% HN(CH₂CH₂CN)₂, b₁₄ 177-9¡ã, b₂₂ 209-11¡ã, n_D²⁰ 1.4630, d₂₀ 1.0196; HCl salt, m. 147-8¡ã (from MeOH); N-Bz derivative, m. 112¡ã (from MeOH). The free amine generated by addition of 50% aqueous Me₂NH to solid NaOH was fed into 106 g. I with ice cooling over 6-8 hrs., and the mixture distilled after 2 hrs. at room temperature yielding 80-1% Me₂NCH₂CH₂CN, b₇₅₀ 171¡ã, n_D²⁰ 1.4283, d₂₀ 0.8705; picrate, m. 151¡ã; HCl salt, m. 199¡ã (from MeOH). A mixture of 40 g. Et₂NH and 26.5 g. I gave a slight heat evolution after 5-10 min.; refluxed on a steam bath 2 hrs. (yellow color) and distilled, it yielded 89-95% Et₂NCH₂CH₂CN, b₂₀ 86-9¡ã. If the heating is done in sealed tubes 6-8 hrs. no yellow color is formed and the yield is nearly 100%; the pure product b₂ 65¡ã, b₉ 76¡ã, b₂₀ 87¡ã, b₄₅ 112¡ã, b₇₅₅ 197.3¡ã (corr.), d₂₀ 0.8761, n_D²⁰ 1.4380; HCl salt, m. 120¡ã; picrate, m. 85¡ã. This (3.1 g.) refluxed 4 hrs. with 4. g. 25% NaOH and evaporated gave the amorphous Na salt of the corresponding acid; refluxing 6.3 g. of the nitrile with 11 g. concentrated HCl, cooling, filtering, and evaporating repeatedly in vacuo gave an amorphous mass, which was freed in aqueous solution of Cl ion by Ag₂CO₃, the Ag ion removed with H₂S, and the filtrate evaporated, yielding 60% Et₂NCH₂CH₂CO₂H, m. 70-5¡ã. The best reaction conditions for piperidine and I are as follows: Piperidine (17 g.) and 11.1 g. I mixed with cooling in an ampul (cooled until the heat evolution stopped in 15-20 min.) and heated 4 hrs. on a steam bath, then let stand overnight, gave 96-7% (CH₂)₅NCH₂CH₂CN, b₁₈ 114-15¡ã; some 22% is formed by refluxing 5 g. piperidine with 5 g. HOCH₂CH₂CN 3 hrs. at 120-50¡ã; if Sn dust is added the yield is 52.5%. An extensive study showed that the reaction of I with PhNHEt is best carried out by heating in an ampul 100 hrs. on steam bath in the presence of 3% Ac₂O and a little hydroquinone, when 65-70% PhEtNCH₂CH₂CN, b₈ 158¡ã, b₁₁ 164-5¡ã, n_D²⁰ 1.5503, d₂₀ 1.0260, is obtained; HCl salt, hygroscopic solid; picrate, oil; the free base couples with diazotized sulfanilic acid even in acid medium and the coupling product, isolated as the Na salt, is a green solid, giving a brown color in acid solution Coupling with diazotized p-O₂NC₆H₄NH₂ gave a brown product, C₁₇H₁₇O₂N₅, while tetrazotized benzidine reacts only slowly in acidified solution, yielding a red-violet solution which turns yellow in neutral or basic solution; the free azo derivative is soluble in organic solvents. Hydrolysis of PhEtNCH₂CH₂CN is very slow with H₂O at 100¡ã in a sealed tube; concentrated HCl at room temperature acts slowly and incompletely even in 48 hrs., while heating at 110-20¡ã leads to loss of PhNHEt; heating with 30-40% H₂SO₄ gives an impure product. Alk. hydrolysis gives low yields of the corresponding acid. Refluxing 14 g. PhEtNCH₂CH₂CN and 20 g. KOH in 20 ml. H₂O and 70 ml. EtOH 15 hrs., acidifying with HCl, and repeatedly extracting with iso-BuOH, adding Et₂O to the extract gave 33.1% PhEtNCH₂CO₂H.HCl, a high-melting solid, giving a brown color with FeCl₃. This couples even in acid solution with diazotized sulfanilic acid, yielding a red azo derivative; p-O₂NC₆H₄N₂Cl also couples in acid medium, giving a red azo derivative PhEtNCH₂CH₂CN (4.5 g.) added slowly to 15 ml. concentrated H₂SO₄, and the mixture let stand 40 hrs., then diluted with H₂O (50 ml.), neutralized with concentrated NH₄OH, and let stand overnight giving a precipitate of PhEtNCH₂CH₂CONH₂, 68.5-76.5%, m. 55-8¡ã (crude), m. 67¡ã (from MeOH). I (35 g.) added to 20 g. dry (CH₂NH₂)₂ dropwise with cooling at 15-20¡ã over 2 hrs. the mixture shaken 2 hrs. at room temperature and let stand overnight in a stoppered flask gave 39.8% H₂NCH₂CH₂NHCH₂CH₂CN, b_1.5 101¡ã, n_D²⁰ 1.4727, d₂₀ 0.9912 (with MeZnI at room temperature only the primary amino group reacts, while at 100¡ã all active H can be determined) (the picrate and styphnate are oils, while HCl salt is a viscous mass), and 59.8% (CH₂NHCH₂CH₂CN)₂, b_1.5 174¡ã, b_3.5 191¡ã, n_D²⁰ 1.4793, d₂₀ 1.0256 [picrate and styphnate, oils; HCl salt, m. 184-7¡ã (decomposition)]. The structure of the latter appears confirmed by the improbability of reaction of I with a cyanoethylated group, and further by the reaction with MeZnI which indicates 1.94 active H atoms/mole at 100¡ã and 0.5 at room temperature Me₂NCH₂CH₂CN treated with MeI in C₆H₆ with cooling gave the methiodide, m. 153¡ã (from MeOH); EtI at room temperature yielded the ethiodide, m. 128.5¡ã (from MeOH); EtBr at 60¡ã yielded the ethobromide, m. 157¡ã (from Et₂O-MeOH); PrBr and CH₂:CHCH₂Cl at 80¡ã yielded the corresponding quaternary salts, m. 189¡ã (from Et₂O-MeOH), and 185-7¡ã (from MeOH), resp. Et₂NCH₂CH₂CN with MeI at room temperature gave the methiodide, m. 152¡ã (from MeOH), while EtI at 60¡ã gave the ethiodide, m. 168¡ã (from MeOH). (CH₂)₅NCH₂CH₂CN with MeI at 100¡ã gave the methiodide, m. 152¡ã (from MeOH), while EtI reacted slowly at 100¡ã yielding the ethiodide, m. 160-1¡ã (from MeOH). Reduction of H₂NCH₂CH₂CN with BuOH-Na gave variable yields when com. Na was used, because of traces of K (Dzirkal, C.A. 36, 2255.6); a 2% K-Na alloy gave high yields comparable to those obtained with pure Na. In the best procedure 30 g. of this alloy was rapidly treated with 14 g. H₂NCH₂CH₂CN in 450 ml. BuOH, and despite vigorous reaction the mixture was immediately heated in an oil bath at 140-50¡ã, cooled after 35-40 min., diluted with 130-50 ml. cold H₂O, steam-distilled 4-6 hrs. into the calculated amount of aqueous HCl, and the distillate evaporated, yielding 81% CH₂(CH₂NH₂)₂.2HCl, m. 242¡ã (from EtOH). Similar reduction of Me₂NCH₂CH₂CN gave 52-6% Me₂NCH₂CH₂ CH₂NH₂, b_128-30 70-80¡ã (crude), b₂₀ 44-5¡ã, b₇₄₈ 133¡ã, n_D²⁰ 1.4415, d₂₀ 0.8272; di-HCl salt, m. 184¡ã (from MeOH); picrate, C₁₇H₂₀N₈O₁₄, m. 211¡ã (from H₂O). The higher-boiling material yielded a little 3,3′-bis(dimethylamino)dipropylamine, b₂₀ 128-31¡ã, n_D²⁰ 1.4531 (HCl salt, hygroscopic solid; tripicrate, m. 200¡ã; chloroplatinate, 2C₁₀H₂₅N₃.3H₂PtCl₆, soluble in H₂O, insoluble in aqueous EtOH). Reduction of Et₂NCH₂CH₂CN with NaBuOH gave 38-63% diamine; a 2% K-Na alloy gave good consistent 60-70% yields; pure Et₂NCH₂CH₂CH₂NH₂, b₁₂ 61-2¡ã, b₇₀ 85-7¡ã, b₈₀ 99-100¡ã, b₇₅₅ 168-70¡ã, n_D²⁰ 1.4435, gave 2 active H with MeZnI at room temperature and at 100¡ã; picrate, m. 190.5¡ã (from MeOH); Bz derivative, oil. Refluxing this amine with an equimolar amount of oleic acid 2 hrs., adding a little amine, heating another hr., concentrating, and evaporating with C₆H₆ gave a product that formed extremely stable organic-aqueous emulsions. The higher-boiling fractions from the above reduction gave a little bis(diethylamino) dipropylamine, b₁₂ 148-50¡ã (picrate, m. 152¡ã), also obtained if the reduction is run with pure Na. Reduction of (CH₂)₅NCH₂CH₂CN with 2% K-Na in BuOH gave 57% 1-(3-aminopropyl)piperidine, b₄ 65-6¡ã, b₉ 79-81¡ã, n_D²⁰ 1.4729. COCl₂ with ROH gave the ClCO₂R: R =Et, b₇₅₂ 92-4¡ã; Pr, b₇₄₂ 114-16¡ã, n_D²⁰ 1.4036; iso-Pr, b₇₄₅ 101-2¡ã, n_D²⁰ 1.3996, d₂₀ 1.0777; Bu, b₁₆ 40-7¡ã, b₇₅₆ 138¡ã, n_D²⁰ 1.4128, d₂₀ 1.0513. COCl₂ with ROH in MePh in the presence of 5-8% quinoline gave the following ClCO₂R: iso-Bu, b₇₅₀ 123-7¡ã; iso-Am, b₇₅₄ 150-1¡ã, n_D²⁰ 1.4176, d₂₀ 1.0490; C₈H₁₇, b₅ 86.5¡ã, b₁₀ 96-7¡ã, b₁₅ 107¡ã, n_D²⁰ 1.4330, d₂₀ 0.9841; cyclohexyl, b₂₅ 80-5¡ã, n_D²⁵ 1.4628; 1-menthyl, b₅ 96¡ã, b₁₁ 108-9¡ã, n_D²⁰ 1.4712; PhCH₂, b₇ 85-7¡ã; with an equimolar amount of quinoline were obtained: sec-Bu, 72%, b₂₃ 30-1¡ã, b₇₄₈ 121-4¡ã, n_D²⁰ 1.4490; 1-methyl-2-cyclohexyl, b₃₀ 101.5¡ã, n_D²⁰ 1.4560; Ph, b₇ 64¡ã, n_D²⁰ 1.5162. The diamines (0.025 mole) in Et₂O were treated with 0.025 mole powd. potash, then 1.5-2 ml. H₂O, and RO₂CCl in Et₂O was added with cooling; the usual treatment gave the desired urethan derivatives: Me₂NCH₂CH₂CH₂NHCO₂Et, 55.8%, b₁₆ 137-7¡ã, n_D²⁰ 1.4480, d₂₀ 0.9653; l-menthyl ester, 51.8%, b₁ 164.5¡ã, n_D²⁰ 1.4706, d₂₀ 0.9557, m. 45¡ã; Et₂NCH₂CH₂CH₂NHCO₂Et, 66.7%, b₇ 130¡ã, n_D²⁰ 1.4503; iso-Pr ester, 53.2%, b_1.5 122-3¡ã, n_D³⁰ 1.4452, n_D²⁰ 1.4493, d₂₀ 0.9367; sec-Bu ester, 42.5%, b₅ 132¡ã, n_D²⁰ 1.4513, d₂₀ 0.9334; C₈H₁₇ ester, 63.3%, b₂ 181.5-2¡ã, n_D³⁰ 1.4528, n_D²⁰ 1.4577, d₂₀ 0.9168; cyclohexyl ester, 46.5%, b_1.5 165-7¡ã, n_D³⁰ 1.4725, n_D²⁰ 1.4752, d₂₀ 0.9765; 2-methylcyclohexyl ester, 81.5%, b₂ 177¡ã, n_D³⁰ 1.4693, n_D²⁰ 1.4723, d₂₀ 0.9679; l-menthyl ester, 88.2%, b₃ 173¡ã, n_D²⁰ 1.4719, d₂₀ 0.9482, m. 31¡ã; Ph ester, 33.6%, b₃ 196-201¡ã, n_D²⁰ 1.4770; PhCH₂ ester, 24%, b₃ 132-5¡ã, n_D²⁰ 1.5030. C₅H₅NCH₂CH₂CH₂NHCO₂Et, 78.3%, b₉ 150-3¡ã, n_D²⁰ 1.4742, d₂₀ 1.0070; Pr ester, 70.4%, b₁₈ 187-8¡ã, n_D²⁰ 1.4735, d₂₀ 0.9935; iso-Pr ester, 62.8%, b₈ 155-8¡ã, n_D²⁰ 1.4706, d₂₀ 0.9878; Bu ester, 62.8%, b₃ 146¡ã, b₅ 167-8¡ã, n_D²⁰ 1.4730, d₂₀ 0.9788; iso-Bu ester, 53.5%, b₂ 136.5-7¡ã, n_D²⁰ 1.4710, d₂₀ 0.9813; iso-Am ester, 66.2%, b₂ 159.5¡ã, n_D²⁰ 1.4712, d₂₀ 0.9749; C₈H₁₇ ester, 63.7%, b₉ 212-13¡ã, n_D²⁰ 1.4720, d₂₀ 0.9550.

Uchenye Zapiski Moskov. Gosudarst. Univ. im. M. V. Lomonosova published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, SDS of cas: 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Keniston, Richard Chace published the artcilePolyamine-pyridoxal 5′-phosphate interaction: effects of pH and phosphate concentration in Schiff’s base formation, Product Details of C3H12Cl2N2, the publication is Physiological Chemistry and Physics (1979), 11(5), 465-70, database is CAplus.

The polyamines, spermine, spermidine, and putrescine, reacted rapidly with pyridoxal phosphate (I) in aqueous solution at neutral pH to yield Schiff bases. At high pH, spermine and spermidine cyclized with I to give aldamines. The rate of reaction of polyamines with I was inversely proportional to the phosphate concentration of the buffer and directly proportional to the pH over the physiol. range (pH 6.0-8.0). Spermine reacted faster, and at a lower molar concentration, than any other amine or amino acid tested.

Physiological Chemistry and Physics published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Product Details of C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Grudzinski, S. published the artcileCyanomethyl esters. V. Reaction of cyanomethyl esters of carboxylic acids with cyanoethylhydrazine, Product Details of C3H12Cl2N2, the publication is Lodz Towarz. Nauk., Wydzial III, Acta Chim. (1965), 85-93, database is CAplus.

cf. CA 65, 681f. The appropriate cyanomethyl ester RCO₂CH₂CN{Alt}{179}(I) treated with H₂-NNH(CH₂)₂CN (II) furnished the following RCONHNH-(CH₂)₂CN (R, % yield) and m.p. (b.p.) given: Me (III), 73, (b_1.5 162-6¡ã); Et (IV), 73, (b_1.5 158-62¡ã); 4-O₂NC₆H₄, 55.5, 164.5-6¡ã; PhOCH₂, 73, 106-8¡ã; AcNHCH₂, 92.5, 108-11¡ã; BzNHCH₂ (V), 89.5, 132-4¡ã; 4-AcNHC₆H₄SO₂NHCH₂, 80, 152-4¡ã; 2-phenyl-4-quinolyl, 39.5, 165-6¡ã. V was prepared by using 20% excess of II, the others by using 100% excess of II. III and IV were prepared by keeping a mixture of the resp. I and II at room temperature 24 hrs. For the others an approx. 1-2M solution of I in a suitable solvent was left with II 24 hrs.

Lodz Towarz. Nauk., Wydzial III, Acta Chim. published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Product Details of C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Grudzinska, P. published the artcileReaction of cyanomethyl esters of carboxylic acids with arylhydrazines. IV. Synthesis of tolylhydrazides, Formula: C3H12Cl2N2, the publication is Lodz Towarz. Nauk., Wydzial III, Acta Chim. (1965), 75-83, database is CAplus.

cf. CA 59, 9969g. The reaction between tolylhydrazine (I) and cyanomethyl esters of carboxylic acids (in mole ratio 2:1) gave the following MeC₆H₄NHNHCOR (II) [R, m.p., and % yield (based on cyanomethyl ester) being given for the reactions conducted in AcOEt and without solvent resp.]: p-II: BZNHCH₂, 176-7¡ã, 95, 98.5; PhSO₂NHCH₂, 178-80¡ã, 95, 97; p-MeC₆H₄SO₂NHCH₂, 163-4¡ã, 97, 100; 4-pyridyl (as HCl salt), 239-41¡ã (decomposition), 73, 87; m-II: BZNHCH₂, 178-9¡ã, 92, 98; PhSO₂NHCH₂, 145-6¡ã, 95, 95; p-MeC₆H₄SO₂– NHCH₂, 158-9¡ã, 90, 94; 4-pyridyl, 161-2¡ã, 69, 81; o-II: Bz-NHCH₂, 172-3¡ã, 80, 89; PhSO₂NHCH₂, 145-6¡ã, 81, 85; p-MeC₆H₄SO₂NHCH₂, 164-5¡ã, 62, 79; 4-pyridyl, 209-10¡ã, 50, 85. The reaction mixture was usually kept 20 hrs. at room temperature In cases where no solid separated, either inoculation or distillation of the solvent in vacuo followed by addition of Et₂O initiated the crystallization

Lodz Towarz. Nauk., Wydzial III, Acta Chim. published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Formula: C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xue, Weijian published the artcilePillar[n]MaxQ: A New High Affinity Host Family for Sequestration in Water, Formula: C3H12Cl2N2, the publication is Angewandte Chemie, International Edition (2020), 59(32), 13313-13319, database is CAplus and MEDLINE.

The authors report the synthesis, x-ray crystal structure, and mol. recognition properties of pillar[n]arene derivative P[6]AS, which the authors refer to as Pillar[6]MaxQ along with analogs P[5]AS and P[7]AS toward guests 1-18. The ultratight binding affinity of P[5]AS and P[6]AS toward quaternary (di)ammonium ions renders them prime candidates for in vitro and in vivo noncovalent bioconjugation, for imaging and delivery applications, and as in vivo sequestration agents.

Angewandte Chemie, International Edition published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C12H9N3O4, Formula: C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia