Category: 10517-44-9

Shechter, Yoram published the artcileNewly Designed Modifier Prolongs the Action of Short-Lived Peptides and Proteins by Allowing Their Binding to Serum Albumin, Name: Propane-1,3-diamine dihydrochloride, the publication is Bioconjugate Chemistry (2012), 23(8), 1577-1586, database is CAplus and MEDLINE.

We found that human serum albumin (HSA) contains a single binding domain for derivatives of long-chain fatty acid (LCFA)-like mols. in which the carboxylate is replaced by sulfonate. Accordingly, we have synthesized 16-sulfo-hexadecanoic acid-N-hydroxysuccinimide ester [HO₃S-(CH₂)₁₅-CONHS], an agent that reacts selectively with the amino side chains of peptides and proteins. A macromol. containing a single 16-sulfohexadecanoate moiety associating with albumin with a K_a value of 0.83¡À0.08¡Á10⁶ M^-1, a sufficient affinity to extend the actions in vivo of such short-lived peptides and proteins. S.c. administration of insulin-NHCO-(CH₂)₁₅-SO₃^– into mice facilitated a glucose-lowering effect 4.3 times in duration and 6.6 times in area under the curve (AUC) as compared to an in vitro equipotent amount of Zn²⁺-free insulin. Similarly, s.c. and i.v. administration of exendin-4-NHCO-(CH₂)₁₅-SO₃^– to mice yielded prolonged and stable reduction in glucose level, 5-9-fold longer than that of exendin-4. Also, a single s.c. administration of human interferon-¦Á2-[NH-CO-(CH₂)₁₅-SO₃^–]₃ to mice yielded circulating antiviral activity over a period of 40 h. In conclusion, a simple, hydrophilic reagent has been engineered, synthesized, and studied. Its linkage to peptides and proteins in a mono-modified fashion yielded hydrophilic, prolonged acting derivatives, due to their acquired ability to associate with serum albumin after administration.

Bioconjugate Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C20H28B2O4S2, Name: Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kohno, Hiroyuki published the artcileEffects of intracerebroventricular administration of aliphatic diamines on ingestive behavior in the rat, HPLC of Formula: 10517-44-9, the publication is Japanese Journal of Pharmacology (1981), 31(2), 211-20, database is CAplus and MEDLINE.

The pharmacol. effects of intracerebroventricularly administered aliphatic diamines on ingestive behavior were measured in male rats adapted to a 4 h/day feeding and drinking schedule. 1,2-Ethanediamine-2HCl (ETD) [333-18-6], 1,3-propanediamine-2HCl (PRD) [10517-44-9], putrescine (PUT) [110-60-1], cadaverine-2HCl (CAD) [1476-39-7], and 1,6-hexanediamine-2HCl (HED) [6055-52-3] suppressed feeding and drinking behavior in a dose-dependent manner, but not unless a relatively high dose (>80 ¦Ìg) was given. The approx. anorectic potency was HED > CAD ¡Ö PUT > ETD > PRD. A sedation was also produced in fairly good parallel to these alterations in feeding and drinking behavior. Thus, there appears to be a relation between the length of the C chain and the potency of the pharmacol. action.

Japanese Journal of Pharmacology published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, HPLC of Formula: 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Myers, Joseph F. published the artcileSynthesis and study of a nickel(II) complex containing a macrocyclic ligand derived from 1,3-diaminopropane and methyl vinyl ketone1, Name: Propane-1,3-diamine dihydrochloride, the publication is Inorganic Chemistry (1973), 12(6), 1238-45, database is CAplus.

The macrocyclic complex I can be synthesized from 1,3-diaminopropane and Me vinyl ketone in the presence of both Ni(II) and H ions. Several derivatives of I are described including 2 where the macrocyclic ligand must be present in a folded configuration within a 6-coordinate complex. The detailed description of the separation and purification of 2 interconvertible isomeric complexes is presented. These isomers are the meso and racemic forms.

Inorganic Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Name: Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Mercer, Sean M. published the artcileDesign, synthesis, and solution behaviour of small polyamines as switchable water additives, Recommanded Product: Propane-1,3-diamine dihydrochloride, the publication is Green Chemistry (2012), 14(3), 832-839, database is CAplus.

The practice of adding salt to water to induce salting out of contaminants or to break emulsions and suspensions is generally avoided industrially because of the expense of the necessary treatment of the salty water afterwards. However, the use of switchable water, an aqueous solvent with switchable ionic strength, allows for reversible generation and elimination of salts in aqueous solution, through the introduction and removal of CO₂. In the effort to improve the efficiency of these switchable salts, a phys. study modeling their reactivity and solution behavior has been performed, resulting in a set of design principles for future switchable water additives. The resulting polyamines synthesized using this template show the highest efficiency recorded for a switchable water additive.

Green Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Recommanded Product: Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kraft, Arno published the artcileBranched non-covalent complexes from carboxylic acids and a tris(tetrahydropyrimidine) base, Category: catalysis-chemistry, the publication is Tetrahedron (1999), 55(13), 3923-3930, database is CAplus.

Non-covalent binding of various carboxylic acids to 1,3,5-tris(1,4,5,6-tetrahydropyrimidin-2-yl)benzene 3 produced 3:1 complexes with good solubility in various non-polar organic solvents. The association constant for a model system was measured to be 61700 ¡À 11900 M^-1 in CD₃OD/CDCl₃ (97: 3), indicating the utility of this interaction between an acid and tri-basic heterocyclic amidine 3 for assembling branched complexes.

Tetrahedron published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ducker, W. A. published the artcileForces between mica surfaces in the presence of rod-shaped divalent counterions, Related Products of catalysis-chemistry, the publication is Langmuir (1992), 8(1), 109-12, database is CAplus.

Recent theor. and exptl. studies have shown that the swelling of some common clay minerals (e.g., montmorillonite) is limited on addition of Ca²⁺ salts because of ion-ion correlation forces. This effect gives rise to strong, short-range attractive forces completely unexpected from classical DLVO theory. The effect was investigated of a rod-shaped divalent ion on the long-range double-layer and short-range solvation forces between mica surfaces in aqueous solution At a concentration of 3 mM this ion both reduces the diffuse double-layer repulsion and creates a strong adhesive min. at a mica-mica separation of about 0.8-0.9 nm, probably because the ion acts as a bridging agent between the facing surfaces. The force measurements are compared with the coagulation behavior of Na⁺-montmorillonite.

Langmuir published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Appleton, T. G. published the artcileComplexes with six-membered chelate rings. II. Proton magnetic resonance study of trimethylenediamine, some methyl-substituted derivatives, and their complexes with platinum(II) and palladium(II), Application of Propane-1,3-diamine dihydrochloride, the publication is Inorganic Chemistry (1970), 9(8), 1807-14, database is CAplus.

PMR spectra of compounds (diamine)(HCl)2, M(diamine)22+, and M(diamine)(NH3)22+ are reported, where M = Pt(II), Pd(II); diamine = trimethylenediamine, 2-methylpropane-1,3-diamine, pentane-2,4-diamine, neopentanediamine, ethylenediamine, meso-butane-2,3-diamine. These spectra are discussed in terms of the conformational behavior of the chelate rings. An unusual Pt-H coupling over 4 saturated bonds is observed in some complexes.

Inorganic Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Application of Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jana, Debasish published the artcileMannich reaction of pyrrole and dimethylpyrrole with monoamines and diamines, Synthetic Route of 10517-44-9, the publication is Tetrahedron Letters (2019), 60(46), 151247, database is CAplus.

The Mannich reaction of pyrrole with ethylenediamine dihydrochloride and formaldehyde gave two compounds: N¹,N¹,N²,N²-tetrakis(pyrrol-2-ylmethyl)ethane-1,2-diamine and 1,3-bis(pyrrol-2-ylmethyl)imidazolidine in poor yields. Conversely, the reaction of pyrrole with propylenediamine dihydrochloride afforded macrocyclic compound I in 50% yield. The reaction of 2,5-dimethylpyrrole with methylamine hydrochloride and formaldehyde gave novel bicycle II. The reaction of 2,5-dimethylpyrrole with ammonium chloride gave the tripodal ligand tris(2,5-dimethylpyrrol-3-yl)methylamine in 62% yield. The structures of 1,3-bis(pyrrol-2-ylmethyl)imidazolidine, I and II were determined by single crystal X-ray diffraction studies.

Tetrahedron Letters published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Synthetic Route of 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tomazin, Ursa published the artcileCombinatorial Synthesis of Acacen-Type Ligands and Their Coordination Compounds, Application In Synthesis of 10517-44-9, the publication is ACS Combinatorial Science (2017), 19(6), 386-396, database is CAplus and MEDLINE.

A highly modular synthetic method for the preparation of acacen-type ligands and their coordination compounds was developed. 46 Acacen-type ligands were synthesized by a combinatorial acid-catalyzed transamination between six primary diamines and eight enaminones. The bis-enaminone products were used as tetradentate ligands for coordination of copper(II), nickel(II), cobalt(II), and palladium(II). Dependence of the preferred E- or Z-configuration of the enaminone ligand on the ¦Á-substituent of the enaminone moiety in solution was determined by NMR and confirmed by x-ray diffraction. The copper(II) complexes were tested for their suitability as catalysts in 3 + 2 cycloaddition of azomethine imine to Me propiolate.

ACS Combinatorial Science published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C7H8INO, Application In Synthesis of 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Syamal, A. published the artcileSyntheses of trimethylenedibiguanide sulfate and copper(II), nickel(II), palladium(II), and zinc(II) complexes of trimethylenedibiguanide, Formula: C3H12Cl2N2, the publication is Journal of Inorganic and Nuclear Chemistry (1978), 40(8), 1606-9, database is CAplus.

[M(H₂L)]Cl₂ (M = Cu, Ni, Pd; H₂L = trimethylenedibiguanide) and ZnL were prepared and characterized by elemental anal., magnetic, electronic, and IR spectral data. The dibiguanide acts as a quadridentate, neutral ligand in [M(H₂L)]Cl₂, and as a quadridentate dibasic ligand in ZnL. The ligand was prepared as H₂L.2H₂SO₄ by fusing [H₂N(CH₂)₃NH₂].2HCl, dicyandiamide, and CuSO₄.5H₂O at 140-145¡ã, and finally removing Cu as CuS.

Journal of Inorganic and Nuclear Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C14H31NO2, Formula: C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia