Category: 1293990-73-4

Panda, Biswajit published the artcileIron catalysis: rust-free future, Synthetic Route of 1293990-73-4, the publication is Chemistry & Biology Interface (2019), 9(6), 273-276, database is CAplus.

The addition of nitrogen to carbon compounds is generally a laborious process. To prevent undesired reactivity of nitrogen generally it needs protection, and sometimes removal of protecting group can be difficult, and also use of protection-deprotection strategy is contrary to the ideality of organic transformations from the point of step- and atom-economy. Legnani et al. reported a resourceful method to add simple NH₂ to alkenes from a hydroxylamine derivative directly which is highlighted herein. A simple iron-catalyzed aminochlorination of alkenes using table salts as chloride source proceeds through a radical mechanism, where it is poised for a wide variety of further functionalization options.

Chemistry & Biology Interface published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Synthetic Route of 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Han, Xiang-Lei published the artcileRegioselective Synthesis of 5-Aminooxazoles via Cp*Co(III)-Catalyzed Formal [3 + 2] Cycloaddition of N-(Pivaloyloxy)amides with Ynamides, Product Details of C6H12F3NO5S, the publication is Organic Letters (2017), 19(22), 6108-6111, database is CAplus and MEDLINE.

A simple and efficient protocol for the regioselective synthesis of 5-aminooxazoles is disclosed. The reaction, catalyzed by a cheap Cp*Co(III) catalyst, starts from easily accessible N-(pivaloyloxy)amides and ynamides. Mild reaction conditions, a broad substrate scope, good functional group tolerance, and good to excellent yields were observed

Organic Letters published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Product Details of C6H12F3NO5S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Qiu, Xu published the artcileSelective Carbon-Carbon Bond Amination with Redox-Active Aminating Reagents: A Direct Approach to Anilines, HPLC of Formula: 1293990-73-4, the publication is Chinese Journal of Chemistry (2021), 39(11), 3011-3016, database is CAplus.

Herein, a novel method for the preparation of anilines ArNH₂ (Ar = 4-methylphenyl, naphthalen-2-yl, 2H-1,3-benzodioxol-5-yl, etc.) from alkylarenes ArCH₂CH₃ via Schmidt-type rearrangement using redox-active amination reagents RONH₂⁺R¹.^–OTf (R = Ns, Ts, tert-butylcarbonyl; R¹ = H, Me, i-Pr), which are easily prepared from hydroxylamines R¹NHOH was reported. Primary amines ArNH₂ and secondary amines ArNHR¹ were prepared from corresponding alkylarenes or benzyl alcs. ArCH(OH)CH₃ under mild conditions. Good compatibility and valuable applications of the transformation were also displayed.

Chinese Journal of Chemistry published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, HPLC of Formula: 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

An, Zhenyu published the artcileA catalyst-free method for the synthesis of 1,4,2-dithiazoles from isothiocyanates and hydroxylamine triflic acid salts, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate, the publication is Organic & Biomolecular Chemistry (2021), 19(28), 6206-6209, database is CAplus and MEDLINE.

A catalyst-free method for the preparation of 1,4,2-dithiazoles I (R = C₆H₅, 3-FC₆H₄, Bn, etc.) is developed by reactions of isothiocyanates with hydroxylamine triflic acid salts. This reaction achieves C-S, C-N, and S-N bond formation, and a range of products are obtained in moderate to good yields. The obvious feature is using shelf-stable hydroxylamine triflic acid salts as a N source to synthesize heterocycles under mild conditions.

Organic & Biomolecular Chemistry published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Jun published the artcileConstruction of 2-alkynyl aza-spiro[4,5]indole scaffolds via sequential C-H activations for modular click chemistry libraries, SDS of cas: 1293990-73-4, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(69), 8656-8659, database is CAplus and MEDLINE.

A strategy developed for sequential C-H activations of indole to construct novel 2-alkynyl aza-spiro[4,5]indole scaffolds, which incorporated both alkyne and spiro-units into indole. Gram-scale synthesis and a one-pot, three-step synthesis demonstrated the utility of this protocol. Hybrid conjugates with an oseltamivir derivative further offered a powerful tool for the construction of a versatile spiroindole-containing library via click chem.

Chemical Communications (Cambridge, United Kingdom) published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C10H19NO3, SDS of cas: 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Grohmann, Christoph published the artcileRh[III]-Catalyzed Direct C-H Amination Using N-Chloroamines at Room Temperature, Computed Properties of 1293990-73-4, the publication is Organic Letters (2012), 14(2), 656-659, database is CAplus and MEDLINE.

An efficient Rh(III)-catalyzed direct C-H amination of N-pivaloyloxy benzamides with N-chloroamines proceeding at room temperature was achieved. The versatile directing group allows for selective mono- and diamination and can be readily converted to give valuable benzamide or aminoaniline derivatives, e.g., I. Mechanistic studies have been carried out to elucidate the reaction pathway.

Organic Letters published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Computed Properties of 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Grohmann, Christoph published the artcileRh[III]-Catalyzed C-H Amidation Using Aroyloxycarbamates To Give N-Boc Protected Arylamines, HPLC of Formula: 1293990-73-4, the publication is Organic Letters (2013), 15(12), 3014-3017, database is CAplus and MEDLINE.

The Rh(III)-catalyzed amidation of C(sp²)-H bonds by the use of electron-deficient aroyloxycarbamates as efficient electrophilic amidation partners is reported. The reaction proceeded under mild conditions with broad functional group tolerance, and pyridine and O-Me hydroxamic acids serve as efficient directing groups, giving access to valuable N-Boc protected arylamines (also Fmoc and Cbz). Preliminary mechanistic experiments are discussed.

Organic Letters published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, HPLC of Formula: 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hu, Zhiyong published the artcileRhodium(III)-Catalyzed Cascade Cyclization/Electrophilic Amidation for the Synthesis of 3-Amidoindoles and 3-Amidofurans, Formula: C6H12F3NO5S, the publication is Organic Letters (2016), 18(9), 2058-2061, database is CAplus and MEDLINE.

A rhodium(III)-catalyzed cascade cyclization/electrophilic amidation of N-tosyl-2-alkynylanilines and 2-alkynylphenols I [R = H, 4-Cl, 4-F, 4-O₂N, 4-F₃C, 4-EtO₂C, 4-Me, 5-Me (locants with respect to aniline or phenol functional group); R¹ = Bu, TBDMSOCH₂, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-FC₆H₄, 4-BrC₆H₄; X = TsN, O; TBDMS = tert-butyldimethylsilyl] with N-pivaloyloxylamides R²CONHOCOt-Bu [R² = PhCH₂, 4-MeC₆H₄CH₂, 3-ClC₆H₄CH₂, 3-BrC₆H₄CH₂, 2-IC₆H₄CH₂, ClCH₂, H₂C:CH, Me₂C:CH, (E)-PhCH:CH] as the electrophilic nitrogen source to yield 3-amidoindoles and 3-amidofurans II [R = H, 4-Cl, 4-F, 4-O₂N, 4-F₃C, 4-EtO₂C, 4-Me, 5-Me; R¹ = Bu, TBDMSOCH₂, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-FC₆H₄, 4-BrC₆H₄; R² = PhCH₂, 4-MeC₆H₄CH₂, 3-ClC₆H₄CH₂, 3-BrC₆H₄CH₂, 2-IC₆H₄CH₂, ClCH₂, H₂C:CH, Me₂C:CH, (E)-PhCH:CH; X = TsN, O] under mild conditions with good functional group tolerance has been developed. The synthetic utility of this reaction has been demonstrated through the derivatization of selected 3-amidoindoles to several heterocycle-fused indoles. The structure of II (R = H; R¹ = 4-BrC₆H₄; R² = PhCH₂) was determined by X-ray crystallog.

Organic Letters published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Formula: C6H12F3NO5S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Song, Liangliang published the artcileRhodium(III)-catalyzed intermolecular cascade annulation through C-H activation: Concise synthesis of rosettacin, SDS of cas: 1293990-73-4, the publication is Molecular Catalysis (2018), 129-134, database is CAplus.

An intermol. annulation of 2-acetylenic aldehydes or ketones with O-substituted N-hydroxybenzamides or N-hydroxyacrylamides through rhodium(III)-catalyzed C-H activation for the synthesis of isoquinolones and indolizinones is developed. This reaction features excellent functional-group tolerance and broad substrate scope, including annulation of various heterocyclic substrates. This approach evaluates the chemoselectivity of the reaction when sterically hindered diaryl-substituted alkynes are incorporated. This method also furnishes an efficient approach for the total synthesis of rosettacin and a topoisomerase I inhibitor.

Molecular Catalysis published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C14H28O5S, SDS of cas: 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lee, Hyunji published the artcileSynthesis and Analysis of Natural-Product-Like Macrocycles by Tandem Oxidation/Oxa-Conjugate Addition Reactions, Related Products of catalysis-chemistry, the publication is Chemistry – A European Journal (2019), 25(26), 6500-6504, database is CAplus and MEDLINE.

Here, a strategy for the preparation of a broad natural-product-like macrocyclic library e.g., I by using the tandem allylic oxidation/oxa-conjugate addition and macrocyclization reactions is reported. Cheminformatic analyses demonstrate that this tetrahydropyran-containing macrocyclic library shows a significant overlap with natural products in the chem. space. This approach can be used for designing libraries that may probe more deeply into natural-product-like space.

Chemistry – A European Journal published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia