Category: 140-28-3

El Hajjaji, Fadoua published the artcileElectrochemical, quantum calculations and Monte Carlo simulation studies of N1,N2-bis(1-phenylethylidene)ethane-1,2-diamine as a corrosion inhibitor for carbon steel in a 1.0 M hydrochloric acid solution, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is Portugaliae Electrochimica Acta (2019), 37(1), 23-42, database is CAplus.

N1,N2-Bis(1-Phenylethylidene)ethane-1,2-diamine (PEED) was tested as a corrosion inhibitor for C-steel in a 1.0 M HCl solution, by using potentiodynamic polarization and electrochem. impedance spectroscopy (EIS) techniques. The results showed that PEED is a very good inhibitor, as its inhibition efficiency reached 93.8%, with a concentration of 1.0 × 10^-3 M, at 298 K. Tafel polarization study revealed that PEED acted as a mixed type inhibitor that obeyed Langmuir adsorption isotherm. The thermodn. activation parameters for the corrosion reaction were calculated and discussed. Quantum chem. parameters and Fukui function were obtained by DMol³/GGA/PW91/DNP+ level of theory, which was performed using Materials Studiov 8.0 software from Biovia-Accelrys. Monte Carlo simulation was implemented to search for the equilibrium configurations of the PEED/Fe(111) adsorption system, in a 1.0 M hydrochloric acid solution

Portugaliae Electrochimica Acta published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kunchur, Harish S. published the artcilePlatinum Assisted Tandem P-C Bond Cleavage and P-N Bond Formation in Amide Functionalized Bisphosphine o-Ph₂PC₆H₄C(O)N(H)C₆H₄PPh₂-o: Synthesis, Mechanistic, and Catalytic Studies, Category: catalysis-chemistry, the publication is Inorganic Chemistry (2022), 61(2), 857-868, database is CAplus and MEDLINE.

The reactions of amide functionalized bisphosphine o-Ph₂PC₆H₄C(O)N(H)C₆H₄PPh₂-o (1) with Pt salts is described. Treatment of 1 with [Pt(COD)Cl₂] yielded a chelate complex, [PtCl₂{o-Ph₂PC₆H₄C(O)N(H)C₆H₄PPh₂-o}κ²-P,P] (2), which on subsequent treatment with LiHMDS formed a novel 1,2-azaphospholene-phosphine complex [PtPhCl{o-C₆H₄{C(O)N(o-PPh₂(C₆H₄))P(Ph)}}κ²-P,P] (3) involving a tandem P–C bond cleavage and P-N bond formation. The same complex 3 on passing dry HCl gas afforded dichloro-complex [PtCl₂{o-C₆H₄{C(O)N(o-PPh₂(C₆H₄))P(Ph)}}κ²-P,P] (5). Complex 2 upon refluxing in toluene or treatment of 1 with [Pt(COD)Cl₂] in the presence of a base at room temperature resulted in pincer complex [PtCl{o-Ph₂PC₆H₄C(O)N(C₆H₄PPh₂-o)}κ³-P,N,P] (4). Reaction of 1 with [Pt(COD)ClMe] at room temperature also afforded the pincer complex [PtMe{o-Ph₂PC₆H₄C(O)N(C₆H₄PPh₂-o)}κ³-P,N,P] (6). Mechanistic studies on 1,2-azaphospholene formation showed the reductive elimination of LiCl to form a phosphonium salt that readily adds one of the P-C bonds oxidatively to the in situ generated Pt⁰ species to form a chelate complex 3. Analogous Pd complex [PdCl₂{o-C₆H₄{C(O)N(o-PPh₂(C₆H₄))P(Ph)}}κ²-P,P] (7) showed excellent catalytic activity toward N-alkylation of amines with alcs. with a very low catalyst loading (0.05 mol %), and the methodol. is very efficient toward the gram scale synthesis of many N-alkylated amines.

Inorganic Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rocha, Ana Fatima Braga published the artcileTreatment administered to newborns with congenital syphilis during a penicillin shortage in 2015, Fortaleza, Brazil, Computed Properties of 140-28-3, the publication is BMC Pediatrics (2021), 21(1), 166, database is CAplus and MEDLINE.

Between 2014 and 2016, Brazil experienced a severe shortage in penicillin supply, resulting in a lack of treatment among some pregnant women and newborns with syphilis and the use of non-evidence-based regimens. This study evaluated all live births in Fortaleza reported with CS in 2015 in order to identify the different therapeutic regimens used in newborns during this period of penicillin shortage. A retrospective cross-sectional study design was conducted using manually extracted data from medical chart review of maternal and infant cases delivered in 2015 from all public maternity hospitals in the city of Fortaleza. Data collection occurred from June 2017 to July 2018. A total of 575 congenital syphilis cases were reported to the municipality of Fortaleza during 2015 and 469 (81.5%) were analyzed. Of these, only 210 (44.8%) were treated with a nationally-recommended treatment. As alternative therapeutic options, ceftriaxone was used in 65 (13.8%), Cefazolin in 15 (3.2%) and the combination of more than one drug in 179 (38.2%). Newborns with serum VDRL titers �:16 (p = 0.021), who had some clin. manifestation at birth (p = 0.003), who were born premature (p < 0.001), with low birth weight (p = 0.010), with jaundice indicative of the need for phototherapy (p = 0.019) and with hepatomegaly (p = 0.045) were more likely to be treated with penicillin according to national treatment guidelines compared to newborns treated with other regimens. During the period of shortage of penicillin in Fortaleza, less than half of the infants reported with CS were treated with a nationally-recommended regimen, the remaining received treatment with medications available in the hospital of birth including drugs that are not part of nationally or internationally-recommended treatment recommendations.

BMC Pediatrics published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Computed Properties of 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Luo, Na published the artcileπ-Face Promoted Catalysis in Water: From Electron-deficient Molecular Cages to Single Aromatic Slides, COA of Formula: C16H20N2, the publication is Chemistry – An Asian Journal (2021), 16(22), 3599-3603, database is CAplus and MEDLINE.

Exploiting noncovalent π-interactions particularly emerging anion-π interactions to drive efficient catalysis is fascinating. Even with exciting progresses, can anion-π activation operate in water remains elusive. Herein, design, synthesis and catalytic studies of a class of water-soluble electron-deficient mol. cages and relevant aromatic slide compounds is reported. The prism-like cages contain three divided, long, cationic aromatic walls which constitute three highly electron-deficient V-shape cavities. They were efficiently synthesized in two steps from a parent triformyl cage in gram-scale. Crystal structure showed the π-walls bind to the counter bromide through strong anion-π interactions. Just 5 mol% of cages were effective in catalyzing decarboxylative Aldol reactions of aldehydes and malonic acid half thioesters in water but not in organic solvents, showing a pronounced hydrophobic amplification effect. Meantime, a series of single π-slides resembling the π-wall of the cage performed equally well, while those lacking an extended π-surface were ineffective, highlighting the essential role of electron-deficient π-face on promoting the conversion.

Chemistry – An Asian Journal published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, COA of Formula: C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Marcioni, Massimo published the artcileSemi-crystalline hydrophobic polyamidoamines: a new family of technological materials, COA of Formula: C16H20N2, the publication is Polymers (Basel, Switzerland) (2021), 13(7), 1018, database is CAplus and MEDLINE.

The hitherto known polyamidoamines (PAAs) are not suitable as structural materials because they are usually water-soluble or swellable in water. This paper deals with the synthesis and characterization of semi-crystalline hydrophobic PAAs (H-PAAs) by combining different bis-sec-amines with bis-acrylamides obtained from C6-C12 bis-prim-amines. H-PAAs were initially obtained in a solution of benzyl alc., a solvent suitable for both monomers and polymers. Their number average mol. weights, M_n, which were determined with ¹H-NMR by evaluating the percentage of their terminal units, varied from 6000 to >10,000. The solubility, thermal properties, ignitability and water resistance of H-PAAs were determined They were soluble in organic solvents, semi-crystalline and thermally stable. The most promising ones were also prepared using a bulk process, which has never been previously reported for PAA synthesis. In the form of films, these H-PAAs were apparently unaffected by water. The films underwent tensile and wettability tests. They showed similar Young moduli (260-263 MPa), whereas the maximum stress and the stress at break depended on the number of methylene groups of the starting bis-acrylamides. Their wettability was somewhat higher than that of common Nylons. Interestingly, none of the H-PAAs considered, either as films or powders, ignited after prolonged exposure to a methane flame.

Polymers (Basel, Switzerland) published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, COA of Formula: C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Abd El-Wahab, Hend A. A. published the artcileDesign, synthesis and evaluation against Mycobacterium tuberculosis of azole piperazine derivatives as dicyclotyrosine (cYY) mimics, Product Details of C16H20N2, the publication is Bioorganic & Medicinal Chemistry (2018), 26(1), 161-176, database is CAplus and MEDLINE.

Three series of azole piperazine derivatives that mimic dicyclotyrosine (cYY), the natural substrate of the essential Mycobacterium tuberculosis cytochrome P 450 CYP121A1, were prepared and evaluated for binding affinity and inhibitory activity (MIC) against M. tuberculosis. Series A replaces one phenol group of cYY with a C3-imidazole moiety, series B includes a keto group on the hydrocarbon chain preceding the series A imidazole, while series C explores replacing the keto group of the piperidone ring of cYY with a CH₂-imidazole or CH₂-triazole moiety to enhance binding interaction with the heme of CYP121A1. The series displayed moderate to weak type II binding affinity for CYP121A1, with the exception of series B 10a, which displayed mixed type I binding. Of the three series, series C imidazole derivatives showed the best, although modest, inhibitory activity against M. tuberculosis (17d MIC = 12.5 μg/mL, 17a 50 μg/mL). Crystal structures were determined for CYP121A1 bound to series A compounds 6a and 6b that show the imidazole groups positioned directly above the haem iron with binding between the haem iron and imidazole nitrogen of both compounds at a distance of 2.2 Å. A model generated from a 1.5 Å crystal structure of CYP121A1 in complex with compound 10a showed different binding modes in agreement with the heterogeneous binding observed Although the crystal structures of 6a and 6b would indicate binding with CYP121A1, the binding assays themselves did not allow confirmation of CYP121A1 as the target.

Bioorganic & Medicinal Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Product Details of C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia