Category: 140-28-3

Khairullin, R. A. published the artcileSynthesis of O,O-Dialkyl S-(1,1-dimethyl-2-oxoethyl) dithiophosphates and their reactions with N-nucleophiles, Quality Control of 140-28-3, the publication is Doklady Chemistry (2016), 467(2), 131-135, database is CAplus.

O,O-Dialkyl S-(1,1-dimethyl-2-oxoethyl) dithiophosphates, 2-(dialkoxythiophosphorylthio)-substituted aldehydes with branched carbon groups, were obtained by hydrolysis of phosphoryl-containing iminium salts. The reaction with primary amines results in imines containing acetal group in different positions. Tri- and tetra-substituted perhydro-1,3-diazoles and oxazoles containing a phosphorus atom in the side chain were prepared by reacting the aldehydes with O,Nand N,N-dinucleophiles.

Doklady Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Quality Control of 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Khairullin, R. A. published the artcileReactions of diphenyldithiophosphinic acid with N-alkyl-2-chloro-2-methylpropanimines, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is Russian Chemical Bulletin (2018), 67(5), 912-915, database is CAplus.

In contrast to O,O-dialkyldithiophosphoric acids, the reactions of more weak diphenyldithiophosphinic acid with N-alkyl-2-chloro-2-methylpropanimines at a 1 : 1 reagent ratio follow two pathways. The first route is nucleophilic substitution of the chlorine atom of the initially formed iminium salt with the diphenylthiophosphinylthio moiety and the second route is the reduction of the C-Cl bond of this iminium salt cation. The main reaction direction is nucleophilic substitution producing new iminium salts, namely, N-alkyl-2-(diphenylthiophosphinylthio)-2-methylpropaniminium chlorides. These salts were used as the starting material to synthesize new organophosphorus compounds bearing aldehyde, imine, and acetal groups and 1,3-diazolidine cycle.

Russian Chemical Bulletin published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Khairullin, R. A. published the artcileReactions of diphenyl- and diethylphosphinodithioic acids with N-alkyl-2-haloaldimines in the synthesis of new P,S- and N,P,S-containing organic compounds, SDS of cas: 140-28-3, the publication is Russian Journal of General Chemistry (2017), 87(10), 2313-2319, database is CAplus.

Diphenyl- and diethylphosphinodithioic acids, unlike the stronger O,O-dialkyl phosphorodithioic acids, react with N-alkyl-2-chloroaldimines at a 1: 1 ratio, following two pathways: nucleophilic substitution of chlorine in the primary salt by the phosphinothioylthio group and reduction of the cation of the primary salt on the C-Cl bond. Nucleophilic substitution contributes more in the case of the stronger diphenylphosphinodithioic acid, as well as in the case of a large excess of the starting chlorimine. N-Alkyl-2-bromoaldimines react only by a single pathway, specifically, reducing the cation of the primary iminium salt on the C-Br bond. New iminium salts were synthesized and converted into the corresponding aldehydes and imines. The aldehydes synthesized were converted into acetals and five-membered heterocyclic compounds

Russian Journal of General Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, SDS of cas: 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Araujo, Raquel Silva published the artcileCloxacillin benzathine-loaded polymeric nanocapsules: Physicochemical characterization, cell uptake, and intramammary antimicrobial effect, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is Materials Science & Engineering, C: Materials for Biological Applications (2019), 110006, database is CAplus and MEDLINE.

The present work shows the development and evaluation of the veterinary antibiotic cloxacillin benzathine loaded into poly-¦Å-caprolactone nanocapsules, as a potential new treatment strategy to manage bovine intramammary infections, such as mastitis. Staphylococcus aureus-induced mastitis is often a recurrent disease due to the persistence of bacteria within infected cells. The mean diameter of NC varied from 241 to 428 nm and from 326 to 375 nm, when determined by dynamic light scattering and by at. force microscopy, resp. In vitro release studies from the NC were performed in two media under sink conditions: PBS with 1% polyethylene glycol or milk. Free CLOXB dissolution occurred very fast in both media, while drug release from the NC was slower and incomplete (below 50%) after 9 h. CLOXB release kinetics from polymeric NC was fitted with the Korsmeyer-Peppas model indicating that CLOXB release is governed by diffusion following Fick’s law. Antimicrobial effect of the intramammary administration of CLOXB-PCL NC in cows with mastitis resulted in no clin. signs of toxicity and allowed complete pathogen elimination after treatment. The in vivo results obtained in this work suggest that CLOXB-PCL NC could be a promising formulation for the treatment of intramammary infections in cattle, considering their physicochem. properties, release profiles and effects on bovine mastitis.

Materials Science & Engineering, C: Materials for Biological Applications published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wales, Steven M. published the artcileReversible Capture and Release of a Ligand Mediated by a Long-Range Relayed Polarity Switch in a Urea Oligomer, Computed Properties of 140-28-3, the publication is Journal of the American Chemical Society (2022), 144(7), 2841-2846, database is CAplus and MEDLINE.

Ethylene-bridged oligoureas characterized by a continuous, switchable chain of hydrogen bonds and carrying a binding site (an N,N’-disubstituted urea) for a hydrogen-bond-accepting ligand (a phosphine oxide) were synthesized. These oligomers show stronger ligand binding when the binding site is located at the hydrogen-bond-donating terminus than when the same binding site is at the hydrogen-bond-accepting terminus. An acidic group at the terminus remote from the binding site allows hydrogen bond polarity, and hence ligand binding ability, to be controlled remotely by a deprotonation/reprotonation cycle. Addition of base induces a remote conformational change that is relayed through up to five urea linkages, reducing the ability of the binding site to retain an intermol. association to its ligand, which is consequently released into solution Reprotonation returns the polarity of the oligomer to its original directionality, restoring the function of the remote binding site, which consequently recaptures the ligand. This is the first example of a synthetic mol. structure that relays intermol. binding information, and these “dynamic foldamer” structures are prototypes of components for chem. systems capable of controlling chem. function from a distance.

Journal of the American Chemical Society published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C21H24O8, Computed Properties of 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Golchoubian, Hamid published the artcileHalochromism, ionochromism, solvatochromism and density functional study of a synthesized copper(II) complex containing hemilabile amide derivative ligand, Formula: C16H20N2, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2015), 913-924, database is CAplus and MEDLINE.

This study investigates chromotropism of newly synthesized 3,3′-(ethane-1,2-diylbis(benzylazanediyl))dipropanamide copper(II) perchlorate complex. The compound was structurally characterized by physico-chem. and spectroscopic methods. X-ray crystallog. of the complex showed that the copper atom achieved a distorted square pyramidal environment through coordination of two amine N atoms and two O atoms of the amide moieties. The pH effect on the visible absorption spectrum of the complex was studied which functions as pH-induced “off-on-off” switches through protonation and deprotonation of amide moieties along with the Cu-O to Cu-N bond rearrangement at room temperature The complex was also observed to show solvatochromism and ionochromism. The distinct solution color changes mainly associated with hemilability of the amide groups. The solvatochromism of the complex was investigated with different solvent parameter models using stepwise multiple linear regression method. The results suggested that the basicity power of the solvent has a dominant contribution to the shift of the d-d absorption band of the complex. D. functional theory, DFT calculations were performed in order to study the electronic structure of the complex, the relative stabilities of the Cu-N/Cu-O isomers, and to understand the nature of the halochromism processes taking place. DFT computational results buttressed the exptl. observations indicating that in the natural pH (5.8) the Cu-O isomer is more stable than its linkage isomer and conversely in alk. aqueous solution

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Formula: C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rivera, Augusto published the artcileCleaner and efficient green chemistry synthesis of N,N’-dibenzyl or N,N’-(2-hydroxybenzyl)-ethane-1,2-diamine,-propane-1,3-diamine and -1,3-diamino-2-propanol, Formula: C16H20N2, the publication is International Journal of Chemistry (Toronto, ON, Canada) (2016), 8(4), 62-68, database is CAplus.

An efficient and highly eco-friendly protocol for the preparation of N,N’-dibenzyl or N,N’-(2-hydroxybenzyl)diamines I [R¹ = O, CH₂, CHOH; R² = H, 2-OH, 4-OCH₃, 4-N(CH₃)₂] via the reduction of the corresponding di-Schiff bases II that produces a good yield using water as a solvent without the need for catalysis or the azeotropic removal of water has been developed. These sym. diimines have been reduced to their corresponding diamines with sodium borohydride using a catalyst- and solvent-free protocol with excellent yield. Mild conditions, high yields, and a simple work-up procedure are the primary benefits of this protocol.

International Journal of Chemistry (Toronto, ON, Canada) published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Formula: C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Mohamadi, Ali published the artcileEfficient route to pre-organized and linear polyaminopolycarboxylates: Cy-TTHA, Cy-DTPA and mono/di- reactive, tert-butyl protected TTHA/Cy-TTHA, Synthetic Route of 140-28-3, the publication is Tetrahedron Letters (2017), 58(15), 1441-1444, database is CAplus and MEDLINE.

Pre-organized polyaminopolycarboxylate chelators Cy-TTHA and Cy-DTPA were synthesized via modular five-step syntheses from com. available starting materials in ?62% and 47% overall yields, resp. Furthermore, strategies are reported for the efficient preparation of mono- and di-reactive, tert-butyl-protected TTHA/Cy-TTHA to selectively functionalize central chelators’ carboxylic acids.

Tetrahedron Letters published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Synthetic Route of 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Mohamadi, Ali published the artcileBrightly Luminescent and Kinetically Inert Lanthanide Bioprobes Based on Linear and Preorganized Chelators, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is Bioconjugate Chemistry (2016), 27(10), 2540-2548, database is CAplus and MEDLINE.

The synthesis, photophys. properties, and kinetic stability of a series of water-soluble, highly emissive Tb(III) and Eu(III) complexes featuring triethylenetetraamine hexaacetic acid (TTHA) and cyclohexyl triethylenetetraamine hexaacetic acid (cyTTHA) chelator scaffolds and carbostyril sensitizers are reported. The unique and modular design of the chelators gives rise to striking quantum yields of emission in aqueous solutions (up to 54%) as well as the characteristic lanthanides’ photophys. properties (long excited-state lifetimes, large effective Stokes shifts, and narrow emission peaks). Furthermore, the preorganized chelators (L3, L4, and L6) bind metal within minutes at ambient temperature yet exhibit substantial resistance to transchelation in the presence of a challenge solution (EDTA, 1 mM). Moreover, the Eu(III) complex of L4 remains stably luminescent in HeLa cells over hours, demonstrating the suitability of these compounds for live-cell imaging applications. Representative chelators suitable for derivatization and protein bioconjugation were also prepared that were functionalized with clickable azide and alkyne moieties, biotin, and trimethoprim (TMP). With exceptional long-wavelength brightness, enhanced kinetic inertness, and an adaptable synthetic route, the reported lanthanide complexes are promising probes and labels for time-gated bioanal., biosensing, and optical microscopy.

Bioconjugate Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wu, Shuang published the artcileCatalyst-Free Construction of Versatile and Functional CS₂-Based Polythioureas: Characteristics from Self-Healing to Heavy Metal Absorption, Name: N1,N2-Dibenzylethane-1,2-diamine, the publication is Macromolecules (Washington, DC, United States) (2019), 52(22), 8596-8603, database is CAplus.

As typical of sulfur-containing polymers, polythiourea is a promising polymeric material because of its outstanding properties such as self-healing, high refractive index, high dielec. constant, and good coordinating ability to heavy metal ions. However, examples of versatile polythioureas are relatively scarce as a result of the limited methods for their synthesis. Herein, we report a mild and easily accessible strategy for the preparation of polythioureas by a catalyst-free copolymerization of CS₂ and diamines in the absence of an inert/anhydrous atm. The copolymerization of 1,8-diamino-3,6-dioxaoctane (DA1) and carbon disulfide was selected as the model reaction for optimizing conditions for the polymerization process. DA1 and CS₂ afforded well-defined polythiourea P1 with high mol. weight (25.5 kg/mol) in good yield (96%) at 45 ¡ãC, which was shown to be mech. robust and readily self-healable. This method displayed a wide scope, providing 23 polythioureas with structural diversity and high mol. weights in excellent yields from CS₂ and com. available diamines. The aliphatic polythiourea P4 was examined for its ability as a heavy metal absorbent, effectively sequestering Hg²⁺ ions with greater than 99.9% efficiency. Hence, this study provides an easily accessible method for synthesizing various polythioureas with diverse structures and functionalities.

Macromolecules (Washington, DC, United States) published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C6H12O2, Name: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia