Category: 14707-75-6

Thomson, Jaclyn published the artcile1,3,5-Triazaadamantan-7-amine, Formula: C7H14N4, the publication is Acta Crystallographica, Section E: Structure Reports Online (2010), 66(10), o2637, database is CAplus and MEDLINE.

7-Amino-1,3,5-triazaadamantane, C₇H₁₄N₄, represents the 1st structurally characterized, isolated triazaadamantane. In the crystal structure, weak intermol. N-H¡¤¡¤¡¤N H bonds link the mols. into columns about the crystallog. 4-fold axis. Crystallog. data are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C14H12O2, Formula: C7H14N4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lin, Huajian published the artcileEnhanced anti-microbial effect through cationization of a mono-triazatricyclodecane substituted asymmetric phthalocyanine, Application of 1,3,5-Triazaadamantan-7-amine, the publication is Journal of Inorganic Biochemistry (2018), 192-198, database is CAplus and MEDLINE.

Antimicrobial photodynamic therapy (aPDT) is an effective way to combat infectious diseases and antibiotic resistance. Photosensitizer is a key factor of aPDT and has triggered extensive research interest. In this study, a new asym. Zn(II) phthalocyanine mono-substituted with a triazatricyclodecane moiety (compound 3) and its cationic N-methylated derivative (compound 4) were synthesized. Their photodynamic antimicrobial activities were evaluated using bioluminescent bacterial strains. Compound 3 showed phototoxicity only toward the Gram-pos. bacteria, whereas the cationic derivative compound 4 exhibited strong anti-bacterial activity against both Gram-pos. and Gram-neg. strains. These bacterial species were eradicated (>4.0 logs or 99.99% killing) at appropriate concentrations of compound 4 with 12.7 J/cm² of red light, demonstrating compound 4 as a potent aPDT agent.

Journal of Inorganic Biochemistry published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Application of 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Pinto, Miguel N. published the artcileTherapeutic Potential of Two Visible Light Responsive Luminescent photoCORMs: Enhanced Cellular Internalization Driven by Lipophilicity, Recommanded Product: 1,3,5-Triazaadamantan-7-amine, the publication is Inorganic Chemistry (2019), 58(21), 14522-14531, database is CAplus and MEDLINE.

Herein we report the synthesis, characterization, and cellular internalization properties of two visible-light active luminescent Mn-based photoCORMs. The enhanced membrane permeability of the photoactive Mn carbonyl complex (photoCORM) derived from a designed lipophilic ligand namely, [Mn(CO)₃(Imdansyl)(L1)](CF₃SO₃) (1) (where L1 = a diazabutadiene-based ligand containing two highly lipophilic adamantyl motifs, Imdansyl = dansylimidazole) promoted rapid internalization within human colorectal adenocarcinoma (HT-29) cells compared to [Mn(CO)₃(Imdansyl)(L2)](CF₃SO₃) (2) (where L2 = a diazabutadiene ligand bearing two hydrophilic 1,3,5-triazaadamantyl group). Colocalization experiments using membrane stain indicate different extents of localization of the two CO complexes within the cellular matrix. Visible-light triggered CO release from the lipophilic photoCORM induced caspase-3/7 activation on HT-29 cells, which was detected using confocal microscopy. The rapid accumulation of the lipophilic photoCORM 1 in the cellular membrane resulted in more efficient CO-induced cell death compared to the hydrophilic analog 2. A photoactive Mn(I) carbonyl complex derived from a designed lipophilic ligand is readily uptaken by cancer cells and leads to CO-induced apoptotic cell death under illumination.

Inorganic Chemistry published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Recommanded Product: 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jimenez, Jorge published the artcileFive- and Six-Coordinated Silver(I) Complexes Derived from 2,6-(Pyridyl)iminodiadamantanes: Sustained Release of Bioactive Silver toward Bacterial Eradication, Recommanded Product: 1,3,5-Triazaadamantan-7-amine, the publication is Inorganic Chemistry (2017), 56(9), 4784-4787, database is CAplus and MEDLINE.

Ag(I) complexes of two designed tridentate ligands, namely, 2,6-(pyridyl)iminoditriazaadamantane (pydTAm) and 2,6-(pyridyl)iminodiadamantane (pydAm), were synthesized and structurally characterized. [Ag(pydTAm)₂](CF₃SO₃) (1), the hitherto unknown mer isomer of a Ag(I) octahedral complex, crystallizes in a highly sym. body centered cubic I4?3m space group. Quite in contrast, the Ag^I center in the analogous [Ag(pydAm)₂](CF₃SO₃) (2) complex resides in a trigonal-bipyramidal geometry and crystallizes in a triclinic P1? space group with two crystallog. independent mols. in the asym. unit. Complex 1 exhibits exceptional solubility in aqueous media and leads to the efficient eradication of several bacterial strains upon sustained release of bioactive Ag.

Inorganic Chemistry published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Recommanded Product: 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Starshinov, A. A. published the artcileThe first examples of synthesis of 1,3-diaza-5-azoniaadamantane-5-oxo-1,3,2,5-dioxaborataphosphorinanes, Recommanded Product: 1,3,5-Triazaadamantan-7-amine, the publication is Zhurnal Obshchei Khimii (1996), 66(7), 1125-1127, database is CAplus.

Borylation of PhP(O)(CHROH)₂ (R = H, C₆H₄Cl-4) with Ph₂BOiBu in the presence of appropriately-substituted triazaadamantanes in Me₂CO and/or MeCN gave 12-62% cyclic title compounds I (R = H, X = H, Cl, NH₂; R = C₆H₄Cl-4, X = NH₂).

Zhurnal Obshchei Khimii published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C9H12O, Recommanded Product: 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kuznetsov, R. M. published the artcileSynthesis of aminomethylphosphines with triazaadamantane fragments, Product Details of C7H14N4, the publication is Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) (2001), 71(6), 899-902, database is CAplus.

The reaction of (hydroxymethyl)diphenylphosphine with 7-amino-1,3,5-triazaadamantane, followed by ready oxidation of the initially formed aminomethylphosphine gave diphenyl[(1,3,5-triazaadamantan-7-yl)aminomethyl]phosphine oxide. The reactions of bis(hydroxymethyl)phenylphosphine with 2 mol of 7-amino-1,3,5-triazaadamantane in the absence and in the presence of Paraform provided bis[(1,3,5-triazaadamantan-7-yl)aminomethyl]phenylphosphine and 1,3-bis(1,3,5-triazaadamantan-7-yl)-5-phenyl-1,3,5-diazaphosphorinane, resp.

Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Product Details of C7H14N4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Arutyunyan, G. L. published the artcileSynthesis and Conversions of Polyhedral Compounds. 32. Synthesis and Antibacterial Activity of Azaadamantane-Containing Azomethine Dihydrochlorides, SDS of cas: 14707-75-6, the publication is Pharmaceutical Chemistry Journal (2018), 52(5), 419-423, database is CAplus.

New azomethines (Schiff bases) containing azaadamantane groups on one side and several biol. active compounds on the other were synthesized. The antibacterial activity of their dihydrochlorides showed that azomethines containing a nitrofuryl group were most active.

Pharmaceutical Chemistry Journal published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, SDS of cas: 14707-75-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Agadzhanyan, Ts. E. published the artcileSynthesis and hypoglycemic activity of N-(arylsulfonyl)-N’-(1,3,5-triazaadamant-7-yl)ureas, Product Details of C7H14N4, the publication is Khimiko-Farmatsevticheskii Zhurnal (1997), 31(1), 17-18, database is CAplus.

The title compounds (I; R = Cl, Me) were prepared by reaction of 7-amino-1,3,5-triazaadamantane with 4-RC₆H₄SO₂NHCOOEt. I (R = Cl) exhibited higher hypoglycemic activity and lower toxicity in mice than I (R = Me).

Khimiko-Farmatsevticheskii Zhurnal published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Product Details of C7H14N4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Burkhard, Jiri published the artcileReactivity of triformylmethane. Part II. Reactions of triformylmethane with adamantane derivatives containing primary amino group, Safety of 1,3,5-Triazaadamantan-7-amine, the publication is Collection of Czechoslovak Chemical Communications (1992), 57(9), 1947-50, database is CAplus.

Six new compounds, e.g., RNHCH:C(CHO)₂ (R = R¹, R¹CO, R¹NHCO; R¹ = 1-adamantyl) were obtained by condensation of triformylmethane with some aminoadamantane derivatives RNH₂. The study also includes the reaction of 7-amino-1,3,5-triazaadamantane I (R = H) with triformylmethane to give I [R = CH:C(CHO)₂]. S-1-Adamantyl)isothiourea hydrochloride reacted with triformylmethane to give pyrimidine derivative II (R = 1-adamantyl).

Collection of Czechoslovak Chemical Communications published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Safety of 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Votyakov, V. I. published the artcileEffect of some 1-aminoadamantane and 1,3,5-triaza-7-adamantylamine derivatives on viruses and rickettsiae, Synthetic Route of 14707-75-6, the publication is Fiziologicheski Aktivnye Veshchestva (1978), 88-92, database is CAplus.

Aminotriazaadamantanes I (R = H, 3-H₂N, 4-O₂N, 2-CO₂H) were prepared in 30-62.6% yields by acylation of the free amine with RC₆H₄CO₂Me. Reduction of I (R = 4-O₂N) gave 59.7% I (R = 4-H₂N). Triazaadamantanes II (R¹ = H, X = O, S; R¹ = N:CMe₂, N:CMePh, N:CHPh, X = O) were prepared in 43-77.8% yields by addition of PhNCX or H₂NCONHR¹ to the triazaadamantylamine. Addnl. obtained were 64.3-85.7% III (R² = 2-, 3-, 4-H₂N).

Fiziologicheski Aktivnye Veshchestva published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C8H7NO4, Synthetic Route of 14707-75-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia