Category: 17351-62-1

Yang, Bo Yeun published the artcileFacile calculation of specific rate constants and activation energies of ¹⁸F-fluorination reaction using combined processes of coat-capture-elution and microfluidics, Name: Tetrabutylammonium hydrogencarbonate, the publication is Tetrahedron (2011), 67(13), 2427-2433, database is CAplus.

Calculation of a specific rate constant (k) and activation energy (E_a) of ¹⁸F-labeling reaction is important to obtain objective data. However, it has never been tried, because short time heating required for the calculation of the parameters was difficult. In the present study, we could calculate the parameters using combination of coat-capture-elution method and microfluidic processes. The E_a values obtained for Ts-naphthol in acetone, MeCN and t-BuOH were 5.83, 8.98, and 13.54 kcal/mol, resp., and for Ms-naphthol in the same solvents were 5.81, 8.16, and 19.34 kcal/mol, resp. Calculation of these parameters might be useful for setting up [¹⁸F]fluorination procedure and for developing new precursors.

Tetrahedron published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C3H5BN2O2, Name: Tetrabutylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

McMullan, Richard published the artcileThe hydrates of the tetrabutyl and tetraisoamyl quaternary ammonium salts, Formula: C17H37NO3, the publication is United States Department of Commerce, Office of Technical Services, PB Report (1959), 12 pp., database is CAplus.

cf. CA 54, 7279i. The compounds (Bu₄N⁺)_nXⁿ-.nyH₂O were prepared, where X is F^–, Cl^–, Br^–, AcO^–, CrO₄^—, WO₄^—, C₂O₄^—, HCO₃^–, HPO₄^—, and y is ?32. They form an isomorphous crystal series which is tetragonal with a = 23.65 ¡À 0.15, c = 12.40 ¡À 0.15 A. A similar series of the type [iso-C₅H₁1)₄N⁺]_nXⁿ-.y’H₂O was prepared, where X is F^–, Cl^–, CrO₄^—,WO₄^—, and y’ is ?40. They also form an isomorphous group which is orthorhombic with a = 12.10 ¡À 0.10, b = 21.50 ¡À 0.15, c = 12.65 ¡À 0.15 A. The compounds prepared are believed to be of the clathrate type, similar in general character to the gas hydrates.

United States Department of Commerce, Office of Technical Services, PB Report published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Formula: C17H37NO3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sachin, Kalme published the artcileF-18 Labeling Protocol of Peptides Based on Chemically Orthogonal Strain-Promoted Cycloaddition under Physiologically Friendly Reaction Conditions, Quality Control of 17351-62-1, the publication is Bioconjugate Chemistry (2012), 23(8), 1680-1686, database is CAplus and MEDLINE.

We introduce the high-throughput synthesis of various ¹⁸F-labeled peptide tracers by a straightforward ¹⁸F-labeling protocol based on a chemo-orthogonal strain-promoted alkyne azide cycloaddition (SPAAC) using aza-dibenzocyclootyne-substituted peptides as precursors with ¹⁸F-azide synthon to develop peptide based positron emission tomog. (PET) mol. imaging probes. The SPAAC reaction and subsequent chemo-orthogonal purification reaction with azide resin proceeded quickly and selectively under physiol. friendly reaction conditions (i.e., toxic chem. reagents-free, aqueous medium, room temperature, and pH ¡Ö7), and provided four ¹⁸F-labeled tumor targetable bioactive peptides such as cyclic Arg-Gly-Asp (cRGD) peptide, bombesin (BBN), c-Met binding peptide (cMBP), and apoptosis targeting peptide (ApoPep) in high radiochem. yields as direct injectable solutions without any HPLC purification and/or formulation processes. In vitro binding assay and in vivo PET mol. imaging study using the ¹⁸F-labeled cRGD peptide also demonstrated a successful application of our ¹⁸F-labeling protocol.

Bioconjugate Chemistry published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Quality Control of 17351-62-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Akai, Shuji published the artcileSynthesis of Long-Chain [¹⁸F]Deoxyfluoropoly(ethylene glycol) Methyl Ethers and Their Noninvasive Pharmacokinetic Analysis by Positron Emission Tomography, COA of Formula: C17H37NO3, the publication is Molecular Pharmaceutics (2011), 8(1), 302-308, database is CAplus and MEDLINE.

[¹⁸F]DeoxyfluoroPEG Me ethers with an average mol. weight of 2 kDa and 10 kDa were synthesized by the fluorination of the tosylates with [¹⁸F]nBu₄NF at 80 ¡ãC for 20 min followed by flash filtration through a Sep-Pak Plus Alumina-N cartridge. After the i.v. administration to rats, their pharmacokinetics was analyzed by noninvasive, real-time, whole-living-body monitoring using positron imaging technol. The effect of PEG’s mol. weight on their blood circulation and organ clearance were quant. visualized for the first time.

Molecular Pharmaceutics published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, COA of Formula: C17H37NO3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Szpera, Robert published the artcileSynthesis of Fluorinated Alkyl Aryl Ethers by Palladium-Catalyzed C-O Cross-Coupling, Computed Properties of 17351-62-1, the publication is Organic Letters (2020), 22(16), 6573-6577, database is CAplus and MEDLINE.

Herein, we report a highly effective protocol for the cross-coupling of (hetero)aryl bromides with fluorinated alcs. using the com. available precatalyst ^tBuBrettPhos Pd G3 and Cs₂CO₃ in toluene. This Pd-catalyzed coupling features a short reaction time, excellent functional group tolerance, and compatibility with electron-rich and -poor (hetero)arenes. The method provides access to ¹⁸F-labeled trifluoroethyl ethers by cross-coupling with [¹⁸F]trifluoroethanol. Safety: 2-fluoroethanol is highly toxic.

Organic Letters published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C12H9NO, Computed Properties of 17351-62-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kim, Sang Wook published the artcileTwo years of experience with the [¹⁸F]FDG production module, Recommanded Product: Tetrabutylammonium hydrogencarbonate, the publication is Nuclear Instruments & Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms (2007), 261(1-2), 816-818, database is CAplus.

Chem. module for a conventional [¹⁸F]FDG production by Bu₄N bicarbonate (TBA) and an acidic hydrolysis was manufactured and evaluated. In this experiment, 75 mM (pH 7.5-7.8) of TBA solution and a ?2-Ci order of [¹⁸F]-fluoride were used for the evaluation. The com. acidic purification cartridge was purchased from GE or UKE. The operation system (OS) was programmed with Lab-View which was selected because of its easy customization of the OS. Small sized solenoid valves (Burkert; type 6124) were selected to reduce the module dimensions (W 350 ¡Á D 270 ¡Á H 250). The total time for the synthesis of [¹⁸F]FDG was 30 ¡À 3 min. The production yield of [¹⁸F]FDG was 60 ¡À 2% on an average at EOS, with the decay uncorrected. The traditional chem. module can provide a good [¹⁸F]FDG production yield by optimizing the operational conditions. The radiochem. purity, radionuclidic purity, acidity, residual solvent, osmolality and endotoxin assess the quality of [¹⁸F]FDG. The examined contents for the quality control of [¹⁸F]FDG are suitable for a clin. application.

Nuclear Instruments & Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Recommanded Product: Tetrabutylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hamacher, K. published the artcileElectrochemical cell for separation of [¹⁸F]fluoride from irradiated ¹⁸O-water and subsequent no carrier added nucleophilic fluorination, Category: catalysis-chemistry, the publication is Applied Radiation and Isotopes (2002), 56(3), 519-523, database is CAplus and MEDLINE.

An electrochem. cell was designed allowing the anodic deposition of n.c.a. [¹⁸F]fluoride solubilized in an ¹⁸O-water target and subsequent n.c.a. nucleophilic ¹⁸F-fluorination. The recovery of the deposited [¹⁸F]fluoride can be achieved in the presence of an aprotic solvent containing a phase-transfer catalyst (PTC). The radioisotope adsorbed electrochem. at the cylindrical surface of a glassy carbon electrode can be dried easily by washing the cell twice with dry aprotic solvents while maintaining a low elec. field. This simple washing step makes an azeotropic drying process obsolete. Accordingly, less basic cryptates like [K?2.2.2.]oxalate or triflate can be used for nucleophilic ¹⁸F-fluorination because loss of activity as a consequence of azeotropic drying under conditions of low basicity does not occur. The usefulness of this technique is exemplified for the n.c.a. synthesis of various ¹⁸F-labeled compounds The radiotracers were synthesized with higher radiochem. yields and under much easier conditions than the conventional ¹⁸F-fluorination procedure which includes an addnl. drying step of the PTC.

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Brugarolas, P. published the artcileSynthesis of meta-substituted [¹⁸F]3-fluoro-4-aminopyridine via direct radiofluorination of pyridine N-oxides, Recommanded Product: Tetrabutylammonium hydrogencarbonate, the publication is Chemical Communications (Cambridge, United Kingdom) (2016), 52(44), 7150-7152, database is CAplus and MEDLINE.

A methodol. for the preparation of 3-fluoro-4-aminopyridine was developed via two-step procedure involving fluorination of 3-bromo-4-nitropyridine N-oxide to yield 3-fluoro-4-nitropyridine N-oxide as an intermediate in first step and its reduction via catalytic hydrogenation in second step. Furthermore, this approach was successfully applied for the preparation of [¹⁸F]3-fluoro-4-aminopyridine. The use of pyridine N-oxides for the preparation of fluoropyridines was unprecedented in chem. literature and had potential to offer a new way for the synthesis of these important structures in pharmaceuticals and radiopharmaceuticals.

Chemical Communications (Cambridge, United Kingdom) published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Recommanded Product: Tetrabutylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Fernandez, Sergio published the artcileA Unified Electro- and Photocatalytic CO₂ to CO Reduction Mechanism with Aminopyridine Cobalt Complexes, Recommanded Product: Tetrabutylammonium hydrogencarbonate, the publication is Journal of the American Chemical Society (2020), 142(1), 120-133, database is CAplus and MEDLINE.

A mechanistic understanding of electro- and photocatalytic CO₂ reduction is crucial to develop strategies to overcome catalytic bottlenecks. In this regard, for a new CO₂-to-CO reduction cobalt aminopyridine catalyst, a detailed exptl. and theor. mechanistic study is herein presented toward the identification of bottlenecks and potential strategies to alleviate them. The combination of electrochem. and in situ spectroelectrochem. together with spectroscopic techniques led us to identify elusive key electrocatalytic intermediates derived from complex [L^N4Co(OTf)₂] (1) (L^N4 = 1-[2-pyridylmethyl]-4,7-dimethyl-1,4,7-triazacyclononane) such as a highly reactive cobalt(I) (1^(I)) and a cobalt(I) carbonyl (1^(I)-CO) species. The combination of spectroelectrochem. studies under CO₂, ¹³CO₂, and CO with DFT disclosed that 1^(I) reacts with CO₂ to form the pivotal 1^(I)-CO intermediate at the 1^(II/I) redox potential. However, at this reduction potential, the formation of 1^(I)-CO restricts the electrocatalysis due to the endergonicity of the CO release step. In agreement with the exptl. observed CO₂-to-CO electrocatalysis at the Co^I/0 redox potential, computational studies suggested that the electrocatalytic cycle involves striking metal carbonyls. In contrast, under photochem. conditions, the catalysis smoothly proceeds at the 1^(II/I) redox potential. Under the latter conditions, it is proposed that the electron transfer to form 1^(I)-CO from 1^(II)-CO is under diffusion control. Then, the CO release from 1^(II)-CO is kinetically favored, facilitating the catalysis. Finally, we have found that visible-light irradiation has a pos. impact under electrocatalytic conditions. We envision that light irradiation can serve as an effective strategy to circumvent the CO poisoning and improve the performance of CO₂ reduction mol. catalysts.

Journal of the American Chemical Society published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Recommanded Product: Tetrabutylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Alauddin, Mian M. published the artcileSynthesis of [¹⁸F]-labeled adenosine analogs as potential PET imaging agents, Formula: C17H37NO3, the publication is Journal of Labelled Compounds & Radiopharmaceuticals (2003), 46(9), 805-814, database is CAplus.

The syntheses of adenosine analogs, 2′-deoxy-2′-[¹⁸F]fluoro-9-¦Â-D-arabinofuranosyladenine ([¹⁸F]-FAA) and 3′-deoxy-3′-[¹⁸F]fluoro-9-¦Â-D-xylofuranosyladenine ([¹⁸F]-FXA) from adenosine via reaction with tetrabutylammonium[¹⁸F]fluoride, are reported. Crude preparations were purified by HPLC to obtain the desired pure products. The radiochem. yields were 10-18% decay corrected (d.c.) for [¹⁸F]-FAA and 30-40% (d.c.) for [¹⁸F]-FXA in 4 and 3 runs, resp. Radiochem. purity was >99% and specific activity was > 74 GBq/¦Ìmol at the end of synthesis (EOS). The synthesis time was 90-95 min from the end of bombardment (EOB).

Journal of Labelled Compounds & Radiopharmaceuticals published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Formula: C17H37NO3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia