Category: 5411-14-3

Garcia, Joel published the artcilePhysical Properties of Eu²⁺-Containing Cryptates as Contrast Agents for Ultrahigh-Field Magnetic Resonance Imaging, Synthetic Route of 5411-14-3, the publication is European Journal of Inorganic Chemistry (2012), 2012(12), 2135-2140, database is CAplus and MEDLINE.

The kinetic stabilities and relaxivities of a series of Eu²⁺-containing cryptates have been investigated. Transmetallation studies, which monitored the change in the longitudinal relaxation rate of water protons in the presence of Ca²⁺, Mg²⁺, and Zn²⁺, demonstrated that the cryptate structure influenced the stability, and two of the cryptates studied were inert to transmetalation in the presence of these endogenous ions. The efficacy of these cryptates was determined at different magnetic field strengths, temperatures, and pH values. Cryptate relaxivity was found to be higher at ultrahigh field strengths (7 and 9.4 T) relative to clin. relevant field strengths (1.4 and 3 T), but the efficiency of these cryptates decreased as the temperature increased. In addition, a variation in pH did not yield significant changes in the efficacy of the cryptates. These studies establish a foundation of important properties that are necessary to develop effective pos. contrast agents for magnetic resonance imaging from Eu²⁺-containing cryptates.

European Journal of Inorganic Chemistry published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Synthetic Route of 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Narkevich, V. B. published the artcileEffects of heptapeptide selank on the content of monoamines and their metabolites in the brain of BALB/C and C57BL/6 mice: a comparative study, Related Products of catalysis-chemistry, the publication is Eksperimental’naya i Klinicheskaya Farmakologiya (2008), 71(5), 8-12, database is CAplus and MEDLINE.

The effect of heptapeptide selank on the content of neurotransmitter monoamines and its metabolites in the brain structures of BALB/C and C57Bl/6 line mice under conditions of the open-field test were studied. Significant interstrain differences in the content of norepinephrine (NE), dopamine (DA), serotonin (5-HT) as well as in the levels of their metabolites in hippocampus, hypothalamus, striatum and frontal cortex of C57Bl/6 and BALB/C mice were demonstrated. In particular, the content of 5-HT and its metabolite 5-oxyindolacetic acid (5-HIAA) in hippocampus of BALB/C mice (with passive stress response) was higher than in the same structure of C57Bl/6 (stress-susceptible) animals. The injection of selank (0.3 mg/kg) led to an increase in the NE level in the hypothalamus of both mice strains. At the same time, selank produced opposite effects on the content of DA metabolites: the concentrations of dioxyphenylacetic (DO-PAC) and homovanillic (HVA) acids were found to increase in frontal cortex and hippocampus of C57Bl/6 mice, while the same parameters in BALB/C mice were demonstrated to decrease. Selank induced a decrease in 5-HT and 5-HIAA levels in the hippocampus of BALB/C mice, but did not affect these parameters in C57Bl/6 animals. The obtained results are indicative of selectivity of the anxiolytic effects of selank.

Eksperimental’naya i Klinicheskaya Farmakologiya published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shamsipur, Mojtaba published the artcileThe synthesis of 1,4-diaza-2,3;8,9-dibenzo-7,10-dioxacyclododecane-5,12-dione and its use in calcium-selective carbon paste electrodes, Category: catalysis-chemistry, the publication is Journal of Inclusion Phenomena and Macrocyclic Chemistry (2001), 40(4), 303-307, database is CAplus.

A synthetic procedure was developed for the preparation of 1,4-diaza-2,3;8,9-dibenzo-7,10-dioxacyclododecane-5,12-dione. A C paste electrode based on the new macrocyclic diamide was constructed for Ca²⁺ determination The calibration graph was linear over a wide concentration range (1.3 ¡Á 10^-6-3.2 ¡Á 10^-3 M) with a near Nernstian slope of 32 mV decade^-1. The limit of detection is 7.9 ¡Á 10^-7 M (0.032 ppm). Selectivity coefficients were tabulated and the working pH range was determined It has a fast response time of <10 s and can be used for at least 3 mo without any considerable divergence in potentials. The electrode was successfully applied to the determination of Ca²⁺ ions in a pharmaceutical preparation

Journal of Inclusion Phenomena and Macrocyclic Chemistry published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C18H22O4, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sharghi, H. published the artcileSynthesis of new lariat ethers containing polycyclic phenols and heterocyclic aromatic compound on graphite surface via Mannich reaction, Product Details of C10H10O6, the publication is Journal of the Iranian Chemical Society (2010), 7(1), 275-288, database is CAplus.

Syntheses of novel lariat ethers containing polycyclic phenols and heterocyclic aromatic compounds using graphite via Mannich reaction were described. For this purpose N-methoxymethyl azacrown ether I was synthesized in nearly quant. yield. The reaction of I with polycyclic phenols and heterocyclic aromatic compounds was performed in 10-20 min in the presence of graphite. The graphite powder can be reused up to five times after simple washing with acetone.

Journal of the Iranian Chemical Society published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C27H29N5, Product Details of C10H10O6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kharalkar, Shilpa S. published the artcileIdentification of novel allosteric regulators of human-erythrocyte pyruvate kinase, Safety of 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Chemistry & Biodiversity (2007), 4(11), 2603-2617, database is CAplus and MEDLINE.

Erythrocyte pyruvate kinase (PK) is an important glycolytic enzyme, and manipulation of its regulatory behavior by allosteric modifiers is of interest for medicinal purposes. Human-erythrocyte PK was expressed in Rosetta cells and purified on an Ni-NTA column. A search of the small-mols. database of the National Cancer Institute (NCI), using the UNITY software, led to the identification of several compounds with similar pharmacophores as fructose-1,6-bisphosphate (FBP), the natural allosteric activator of the human kinases. The compounds were subsequently docked into the FBP binding site using the programs FlexX and GOLD, and their interactions with the protein were analyzed with the energy-scoring function of HINT. Seven promising candidates, compounds 1-7, were obtained from the NCI, and subjected to kinetics anal., which revealed both activators and inhibitors of the R-isoenzyme of PK (R-PK). The allosteric effectors discovered in this study could prove to be lead compounds for developing medications for the treatment of hemolytic anemia, sickle-cell anemia, hypoxia-related diseases, and other disorders arising from erythrocyte PK malfunction.

Chemistry & Biodiversity published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Safety of 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Jian-feng published the artcileQuantum chemical calculation on properties of phenoxy acetic acids depressants, COA of Formula: C10H10O6, the publication is Zhongguo Youse Jinshu Xuebao (2004), 14(8), 1437-1441, database is CAplus.

Quantum chem. of phenoxy acetic acids depressants was studied at B3LYP/6-31G^* level by d. functional theory (DFT). The ratio of bond charge d. (¦Ñ(O-H)/¦Ñ(C-O)) for dissociating carboxylic group in each reagent was put out as the judgment for dissociation extent. Frontier orbital energy calculation of the reagents and their corresponding univalence anions approved the traditional theory that mols. in lower ¦¤E_HOMO-LUMO has greater reactivity, and that univalence anion in lower HOMO energy causes greater reactivity with active metal ion on the mineral surface. Energy variation between the univalence anion and the mineral surface reveals that such reagents make intensive adsorption on the surface of calcite and diaspore.

Zhongguo Youse Jinshu Xuebao published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C8H17Br, COA of Formula: C10H10O6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Jian-feng published the artcilePhase transfer catalyzed synthesis and flotation performance of isomers of biphenoxyl bi(acetic acid), COA of Formula: C10H10O6, the publication is Zhongguo Youse Jinshu Xuebao (2001), 11(4), 707-711, database is CAplus.

In the presence of tributylethylammonium ethylsulfate as a phase-transfer catalyst, three isomers of biphenoxyl bi(acetic acid) (I) are synthesized from biphenol, chloroacetic acid and sodium hydroxide in a chloroform solvent. The flotation depressing performance of I for calcite, diaspore and pyrite was studied. I possesses a depressing ability to the three minerals in the order calcite > diaspore > pyrite. I can be used as an efficient depressant for calcite and diaspore. Electronegativity of the group, reagent specific exponent and HLB of I are discussed. Quantum calculations were done by using the Mopac method on an MSI workstation which explained the depressing mechanism and structure-performance relations of the synthesized flotation depressants.

Zhongguo Youse Jinshu Xuebao published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C8H17Br, COA of Formula: C10H10O6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Jian-feng published the artcileFlotation depression of calcite by phenoxy carboxylic acid, Application of 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Zhongnan Gongye Daxue Xuebao, Ziran Kexueban (2001), 32(2), 146-149, database is CAplus.

A new type of flotation reagents, phenoxy-containing (acetic acid compounds), were prepared by treating phenol or a polyphenol, such as dihydroxybenzene and v-trihydroxybenzene, with chloroacetic acid in an alkali solution Controlling the reaction pH value and developing a new self-sealing method brought about a good synthesizing result with high yield and selectivity. It has been shown that the synthesized chems., especially the product of pyrogallol and gallic acid reacting with chloride acetic acid, act as effective depressants in the flotation of calcite. When sodium oleate with 1 x 10^-4 mol/L is used as a collector, calcite can be completely depressed when the concentration of two chems. is 4 x 10^-5 mol/L and 5 x 10^-5 mol/L at pH value 8.78 and 8.47, resp. The electronegativity of group, reagent specific exponent and HLB are discussed, which have explained the depressing mechanism and structure-property relationship of the synthesized chems.

Zhongnan Gongye Daxue Xuebao, Ziran Kexueban published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C9H12O3S, Application of 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Jian-Feng published the artcileDetermination and quantum chemical calculation of the acid dissociation constants of some phenoxy acetic acids, SDS of cas: 5411-14-3, the publication is Yingyong Huaxue (2004), 21(8), 766-769, database is CAplus.

The acid dissociation constants of seven phenoxy acetic acids were determined by potentiometric titration It has been shown that phenoxy acetic acids exhibit stronger acidity than both acetic acid and benzoic acid due to the induction and conjugation of the oxygen atom on -OCH₂COOH that links to the benzene ring. Acidity of phenoxy acetic acids containing two or more -OCH₂ COOH groups is lower than that of phenoxy acetic acid by reason of electron donation of oxygen atom to the benzene ring. Quantum chem. calculation of the phenoxy acetic acids was carried out using CNDO/2 method. The bond charge d.(¦Ñ) of 0-H and C-O bond in carboxyl group of seven phenoxy acetic acids was calculated, and the value f=¦Ñ_O-H/¦Ñ_C-C, was figured out. The f value of the carboxyl group in phenoxy acetic acid as well as the f values of the most likely dissociated carboxyl group in other six phenoxyl acetic acid derivatives are changed in the corresponding change order of their pK_a or pK_a1 values. It is concluded that the f value can be used as a judgement criterion of relative acidity for phenoxy acetic acids.

Yingyong Huaxue published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C6H8O3, SDS of cas: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gao, Jin Sheng published the artcilecatena-Poly[[[tetraaquacobalt(II)]-¦Ì-4,4′-bipyridine-¦Ê²N:N’] 1,2-phenylenedioxydiacetate 4,4′-bipyridine hemisolvate dihydrate], HPLC of Formula: 5411-14-3, the publication is Acta Crystallographica, Section E: Structure Reports Online (2006), 62(11), m2913-m2915, database is CAplus.

In the title compound, {[Co(C₁₀H₈N₂)(H₂O)₄](C₁₀H₈O₆).0.5C₁₀H₈N₂.2H₂O}_n, the Co atoms are bridged into a chain by 4,4′-bipyridine units; both the bridging and the uncoordinated 4,4′-bipyridine mols. are arranged around inversion centers and are centrosym. Two-dimensional fishing-net layers are built up through O-H¡¤¡¤¡¤N H-bond interactions. The diacid anions and uncoordinated H₂O mols. fill the space between the layers. A 3-dimensional supramol. network is built up by O-H¡¤¡¤¡¤O and O-H¡¤¡¤¡¤N H-bond interactions between H₂O mols., anions and 4,4′-bipyridine mols. Crystal data: triclinic, space group P1?, a 9.7417, b 11.443(2), c 13.916(3) ?, ¦Á 73.19(3), ¦Â 80.46(3), ¦Ã 69.63(3)¡ã, Z = 2, d_c = 1.496, 5567 observed reflections with I > 2¦Ò(I), R[F² > 2¦Ò(F²)] = 0.031, wR(F²) = 0.081.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, HPLC of Formula: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia