Catalysis-chemistry

Xiao, Ke published the artcileSimultaneous achievement of refractory pollutant removal and energy production in saline wastewater treatment, Safety of 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2019), 845-853, database is CAplus.

A novel solar-wastewater-energy recovery system was presented to simultaneously remove refractory organic pollutants from saline wastewater and produce energy. To accomplish this goal, a two-chamber cell was fabricated. The anode chamber integrating photo-oxidation and flocculation was developed by using a TiO₂ nanotube array (TNA) and Al foil. A dopamine modified carbon felt (DPA/CF) electrode was located in the cathode chamber to produce H₂O₂ by the two-electron reduction of O₂ with electrons generated on the anodes. Under sunlight irradiation, the TNA photoanode initiated the degradation of perfluorodecylamine (PFDA) as typical refractory pollutant and selectively transformed its organic nitrogen to N₂ and NO₃^– with yields of 87% and 12%, resp. Compared with PFDA removal efficiency using single flocculation, the efficiency was improved by more than 5 times (ca. 96.6%) in the combined process of photo-oxidation and flocculation. H₂O₂ production was also achieved using the DPA/CF cathode, obtaining a high concentration of 5.0 mM. Furthermore, this study revealed that the reversible reaction between dehydrogenation and hydrogenation on polydopamine accomplished the catalytic reduction of O₂ to H₂O₂. The present study proposes a new approach involving energy recovery in saline wastewater treatment for an energy-sustainable society.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 30670-30-5. 30670-30-5 belongs to catalysis-chemistry, auxiliary class Polyfluoroalkanes, name is 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine, and the molecular formula is C12H25Br, Safety of 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Suh, Sung-Eun published the artcileSite-Selective Copper-Catalyzed Azidation of Benzylic C-H Bonds, Product Details of C13H10F2, the publication is Journal of the American Chemical Society (2020), 142(26), 11388-11393, database is CAplus and MEDLINE.

Site selectivity represents a key challenge for non-directed C-H functionalization, even when the C-H bond is intrinsically reactive. Here, we report a copper-catalyzed method for benzylic C-H azidation of diverse mols. Exptl. and d. functional theory studies suggest the benzyl radical reacts with a Cu^II-azide species via a radical-polar crossover pathway. Comparison of this method with other C-H azidation methods highlights its unique site selectivity, and conversions of the benzyl azide products into amine, triazole, tetrazole, and pyrrole functional groups highlight the broad utility of this method for target mol. synthesis and medicinal chem.

Journal of the American Chemical Society published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C18H34N4O5S, Product Details of C13H10F2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hu, Huayou published the artcileCopper-catalyzed benzylic C-H coupling with alcohols via radical relay enabled by redox buffering, Formula: C13H10F2, the publication is Nature Catalysis (2020), 3(4), 358-367, database is CAplus and MEDLINE.

Copper-catalyzed oxidative cross-coupling of benzylic C-H bonds with alcs. to afford benzyl ethers, enabled by a redox buffering strategy that maintains the activity of the copper catalyst throughout the reaction was reported. The reactions employ the C-H substrate as the limiting reagent and exhibit broad scope with respect to both coupling partners. This approach to direct site-selective functionalization of C(sp³)-H bonds provides the basis for efficient three-dimensional diversification of organic mols. and should find widespread utility in organic synthesis, particularly for medicinal chem. applications.

Nature Catalysis published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Formula: C13H10F2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jiang, Chao published the artcileCopper-catalyzed benzylic C-H bond thiocyanation: enabling late-stage diversifications, Recommanded Product: Bis(4-fluorophenyl)methane, the publication is CCS Chemistry (2021), 3(8), 1884-1893, database is CAplus.

The rapid growth of using C-H bond as cross-coupling partners is reshaping the landscape of organic synthesis. C(sp³)-H functionalization via hydrogen atom transfer (HAT) represents the most compelling strategy in this avenue. Here, authors demonstrate an efficient method for benzylic C-H bond thiocyanation via copper-catalyzed radical relay. The reaction exhibits broad substrate scope and exquisite benzylic selectivity with C-H substrates as limiting reagents. In addition, the benzyl thiocyanates are readily converted to other pharmaceutically important motifs, including isothiocyanate, thiourea, and others, highlighting the broad utility of this method.

CCS Chemistry published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Recommanded Product: Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Greer, Alexander published the artcileExperimental and ab Initio Computational Evidence for New Peroxidic Intermediates (Iminopersulfinic Acids). Substituent Effects in the Photooxidations of Sulfenic Acid Derivatives, SDS of cas: 19117-31-8, the publication is Journal of the American Chemical Society (1997), 119(19), 4380-4387, database is CAplus.

A detailed ab initio study of the structures and energetics of the persulfoxides and thiadioxiranes derived from sulfenic acid derivatives (RSX) is reported. The persulfoxides adopt structures in which the O-O bond bisects the RSX angle while the thiadioxiranes prefer a distorted trigonal bipyramidal geometry. The thiadioxiranes are more stable in every case than their persulfoxide isomer. The exothermicities of the interconversions of the persulfoxide to the thiadioxirane increase in the substituent (X) order CH₃ < NH₂ < Cl < OCH₃ < SCH₃ < F from a low of 3 kcal/mol to a high of 31 kcal/mol. The activation barriers, on the other hand, decrease in the substituent order Cl > CH₃ ¡Ö NH₂ > OCH₃ ¡Ö SCH₃ > F from 27 to 10 kcal/mol. Only those persulfoxides which do not have a hydrogen on a heteroatom X exist in well-defined min. on the potential energy surface. Attempted minimization with tight convergence criteria of persulfoxides with heteroatom X-H bonds resulted in collapse via ene-like reactions to give hydroperoxy sulfonium ylides. In the case where X-H is N-H, the resulting hydroperoxysulfonium ylide (iminopersulfinic acid) adopts a hydrogen-bonded structure reminiscent of peracids. Exptl. evidence for the formation of these new peroxides was obtained by photooxidations of N-methyl-, N-n-butyl-, and N-tert-butylbenzenesulfenamides.

Journal of the American Chemical Society published new progress about 19117-31-8. 19117-31-8 belongs to catalysis-chemistry, auxiliary class Oxidant, name is N-(tert-Butyl)-S-phenylthiohydroxylamine, and the molecular formula is C10H15NS, SDS of cas: 19117-31-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Clennan, Edward L. published the artcileExperimental and computational evidence for the formation of iminopersulfinic acids, COA of Formula: C10H15NS, the publication is Journal of Organic Chemistry (1998), 63(10), 3397-3402, database is CAplus.

An exptl. and computational study of the reactions of singlet O₂ with N-substituted sulfenamides is reported. Intermediates capable of epoxidizing norbornene were observed during the photooxidations of PhSNHR (R = Me, Bu, CMe₃). These results are used to argue for the formation of iminopersulfinic acids. The structural integrity of 2 iminopersulfinic acids was supported by their successful location at the MP2/6-31G^* level of theory. Furthermore, the inability to locate computationally significant persulfinimide precursors suggests that the iminopersulfinic acids form by ene-like reactions involving near-simultaneous addition of singlet O₂ to S and H abstraction.

Journal of Organic Chemistry published new progress about 19117-31-8. 19117-31-8 belongs to catalysis-chemistry, auxiliary class Oxidant, name is N-(tert-Butyl)-S-phenylthiohydroxylamine, and the molecular formula is C10H15NS, COA of Formula: C10H15NS.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Xinxi published the artcileRapid and non-invasive surface-enhanced Raman spectroscopy (SERS) detection of chlorpyrifos in fruits using disposable paper-based substrates charged with gold nanoparticle/halloysite nanotube composites, Application In Synthesis of 13822-56-5, the publication is Microchimica Acta (2022), 189(5), 197, database is CAplus and MEDLINE.

Chlorpyrifos is one of the most widely used organophosphate insecticides in agricultural production Nevertheless, the residues of chlorpyrifos in agricultural byproduct seriously threaten human health. Thus, the ultrasensitive detection of chlorpyrifos residues in agri-food products is of great demand. Herein, an AuNP/HNT-assembled disposable paper SERS substrate was prepared by an electrostatic self-assembly method to detect chlorpyrifos residues. The AuNP/HNT paper substrate exhibited high SERS activity, good reproducibility, and long-term stability, which was successfully used for quant. detection of chlorpyrifos; the detection limit reached 7.9 x 10-9 M. For spiked apple samples the calculated recovery was 87.9% with a RSD value of 6.1%. The excellent detection ability of AuNP/HNT paper-based SERS substrate indicated that it will play an important role in pesticide detection in the future. Graphical abstract: AuNP/HNT assembled disposable paper SERS substrate was prepared by an electrostatic self-assembly method to detect chlorpyrifos residues in fruits. [graphic not available: see fulltext].

Microchimica Acta published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C7H8BNO4, Application In Synthesis of 13822-56-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chi, Fuyun published the artcileJAK3 inhibitors based on thieno[3,2-d]pyrimidine scaffold: design, synthesis and bioactivity evaluation for the treatment of B-cell lymphoma, COA of Formula: C8H7NO4, the publication is Bioorganic Chemistry (2020), 103542, database is CAplus and MEDLINE.

JAK3 is predominantly expressed in hematopoietic cells and has been a promising therapeutic target for the treatment of B-cell lymphoma. In this study, a new class of thieno[3,2-d]pyrimidines harboring acrylamide pharmacophore were synthesized as potent covalent JAK3 inhibitors (IC₅₀ < 10 nM). Among them, 9a and 9 g displayed the strongest inhibitory potency against JAK3 kinase activity, with IC₅₀ values of 1.9 nM and 1.8 nM, resp. Furthermore, compared with the reference agents, Spebrutinib and Ibrutinib, 9a not only demonstrated enhanced antiproliferative activity against B lymphoma cells, but also showed very weak proliferative inhibition against normal peripheral blood mononuclear cells (PBMCs) at a concentration of 20¦ÌM. Anal. of the mechanism revealed that 9a could induce the obvious apoptosis in B lymphoma cells and prevent JAK3-STAT3 cascade as well as BTK pathway. Taken together, 9a may be served as a potential new JAK3 inhibitor for the treatment of B-cell lymphoma.

Bioorganic Chemistry published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C8H7NO4, COA of Formula: C8H7NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ruan, Mengyao published the artcileElectrochemical two-electron oxygen reduction reaction (ORR) induced aerobic oxidation of ¦Á-diazoesters, Synthetic Route of 104-03-0, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(13), 2168-2171, database is CAplus and MEDLINE.

The recent progress in the oxidation of ¦Á-diazoesters R¹C(=N₂)C(O)OR² (R¹ = Ph, 2-naphthyl, benzo[d][1,3]dioxol-5-yl, etc.; R² = Me, cyclohexyl, (tetrahydrofuran-2-yl)methyl, etc.) to ¦Á-ketoesters R¹C(O)C(O)OR² by in situ generated hydrogen peroxide via a two-electron oxygen reduction approach was described. A diverse collection of valuable ¦Á-ketoester products was obtained with moderate to high yields under an exogenous-oxidant-free and metal catalyst-free electrochem. conditions.

Chemical Communications (Cambridge, United Kingdom) published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C8H7NO4, Synthetic Route of 104-03-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ni, Xiu-Wen published the artcileA photocontrollable thermosensitive chemical spatiotemporally destabilizes mitochondrial membranes for cell fate manipulation, Application In Synthesis of 71989-31-6, the publication is Biomaterials Science (2022), 10(10), 2550-2556, database is CAplus and MEDLINE.

Perturbations in mitochondrial membrane stability lead to cytochrome c release and induce caspase-dependent apoptosis. Using synthetic smart chems. with changeable physicochem. properties to interfere the mitochondrial membrane stability has not yet been reported. Here we show that a thermosensitive anchor-polymer-peptide conjugate (anchor-PPC) destabilizes mitochondrial membranes upon in situ mol. changes from hydrophilic to hydrophobic, which consequently induces apoptosis in a spatiotemporally controlled manner and acts as an antitumor pharmaceutical. The anchor-PPC is composed of a thermosensitive copolymer, a photolabile linker, a hydrophilic HIV Tat-derived peptide both for cell penetration and polymer phase transition temperature (Tt) modulation, and an anchor peptide for intercalating into mitochondrial membranes. The photocontrollable anchor-PPC dehydrates and changes from being hydrophilic to hydrophobic upon photoactivation at body temperature This cell-penetrable anchor-PPC specifically targets mitochondria and destabilizes mitochondrial membranes upon irradiation, and consequently initiates apoptosis in cells and a complex 3D tumor model. This study provides the first exptl. evidence that the synthetic smart chem. can spatiotemporally control the stability of organelle membranes based on its in situ physicochem. property change.

Biomaterials Science published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Application In Synthesis of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia