Tag: M.W=200-250

Balatoni, Istvan published the artcileDisilene Fluoride Adducts versus ¦Â-Halooligosilanides, Formula: C12H10F2Si, the publication is Inorganic Chemistry (2019), 58(20), 14185-14192, database is CAplus and MEDLINE.

Extending the chem. of disilene fluoride adducts studied earlier by us, we investigated the formation of 1,1-bis(trimethylsilyl)fluorodiphenylsilylsilanide, which was prepared by reaction of (Me₃Si)₃SiSiPh₂F with KO^tBu. The formed FPh₂SiSi(Me₃Si)₂K displays distinctively different structural and spectroscopic features compared to the earlier reported F(Me₃Si)₂SiSi(SiMe₃)₂K. While the latter eliminates metal fluoride upon reaction with MgBr₂, the resp. magnesium silanide is formed from FPh₂SiSi(Me₃Si)₂K. Reaction of (Me₃Si)₃SiSiPh₂Cl with KO^tBu proceeded similarly, but the formed ClPh₂SiSi(Me₃Si)₂K easily undergoes potassium chloride elimination to the disilene Ph₂Si:Si(SiMe₃)₂. Compared to F(Me₃Si)₂SiSi(SiMe₃)₂K, which can be regarded as a disilene fluoride adduct, structural, spectroscopic, and reactivity properties of FPh₂SiSi(Me₃Si)₂K distinguish it as a ¦Â-fluorodisilanide. Potassium 2-fluoro- and 2-chloro-2,2-diphenyl-1,1-bis(trimethylsilyl)disilanides can be prepared by reaction of fluoro- and chlorodiphenylsilyltris(trimethylsilyl)silanes with KOtBu. Structural and spectroscopic evidence characterizes these compounds as ¦Â-oligosilylsilanides, which is in contrast to the previously observed 2-fluoro-1,1,2,2-tetrakis(trimethylsilyl)disilanides, which can be regarded as disilene fluoride adducts.

Inorganic Chemistry published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Formula: C12H10F2Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Balatoni, Istvan published the artcile¦Â-amino- and alkoxy-substituted disilanides, Related Products of catalysis-chemistry, the publication is Molecules (2019), 24(21), 3823, database is CAplus and MEDLINE.

Our recent study on formal halide adducts of disilenes led to the investigation of the synthesis and properties of ¦Â-fluoro- and chlorodisilanides. The reaction of the functionalized neopentasilanes (Me₃Si)₃SiSiPh₂NEt₂ and (Me₃Si)₃SiSiMe₂OMe with KOtBu in the presence of 18-crown-6 provided access to structurally related ¦Â-alkoxy- and amino-substituted disilanides. The obtained Et₂NPh₂Si(Me₃Si)₂SiK¡¤18-crown-6 was converted to a magnesium silanide and further on to Et₂NPh₂Si(Me₃Si)₂Si-substituted ziroconocene and hafnocene chlorides. In addition, an example of a silanide containing both Et₂NPh₂Si and FPh₂Si groups was prepared with moderate selectivity. Also, the analogous germanide Et₂NPh₂Si(Me₃Si)₂GeK¡¤18-crown-6 could be obtained.

Molecules published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rosenwald, R. H. published the artcileAlkyl phenols as antioxidants, COA of Formula: C12H16O3, the publication is Industrial and Engineering Chemistry (1950), 162-5, database is CAplus.

A number of Me- and Bu-substituted phenols were tested as stabilizers for cracked gasoline, and the effects on stabilizing potency of number of substituents and their size, position, and configuration were studied. Potency of a phenol as stabilizer was found to increase with increased number of substituents, but size of substituent had little effect. Substituting in the ortho position was most effective, and the tert-Bu group gave best results. The best stabilizer studied was 2,4-dimethyl-6-tert-butylphenol. Phys. properties reported for new compounds are: 2-methyl-6-sec-butylphenol b_2.5 81.5-2¡ã, 229-31¡ã, n_D²⁰ 1.5197; 2,4-dimethyl-6-sec-butylphenol b_2.5 91-2.5¡ã, n_D²⁰ 1.5189; 2-tert-butyl-4-butylphenol b. 270-2¡ã, n_D²⁰ 1.5089; 2-tert-butyl-4-isobutylphenol b. 259-60¡ã, b_2.5 105-106¡ã, n_D²⁰ 1.5070; 2-tert-butyl-sec-butylphenol b. 255-6¡ã, n_D²⁰ 1.5078.

Industrial and Engineering Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, COA of Formula: C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

De Wet, J. R. published the artcileThe influence of cyanide on the flotation of pyrite from Witwatersrand gold leach residues, Recommanded Product: Dodecylamineacetate, the publication is Minerals Engineering (1995), 8(11), 1333-45, database is CAplus.

A significant portion of the gold in Witwatersrand ores may occur in the pyritic fraction, which seldom comprises >4% of the ore. Consequently, pyrite recovery through flotation offers an opportunity to increase gold recovery through further treatment of the concentrate The traditional processing routes are no longer economically viable due to the high cost of acid treatment to overcome the depressing influence of cyanide on xanthate flotation. Amines were identified as possible alternative collectors for pyrite flotation in the presence of cyanide. The influence of cyanide on pyrite flotation with dodecylamine acetate (I) was investigated by using electrochem. impedance measurements, flotation tests, and in-situ Raman spectroscopy. Cyanide acted as a slight depressant or no depressant at all for the flotation of pyrite with I, a much smaller effect than that which cyanide has on pyrite flotation with xanthate. In pH 11 solutions, pyrite electrodes exhibited a lower interfacial capacitance in the presence of I and reflect the formation of a layer on the electrode surface by adsorption of the cationic amine collector on the pyrite surface. At cyanide concentrations typical of gold leaching, this capacitance decrease is not observed and probably reflects an inhibiting effect of cyanide on amine adsorption. Raman spectroscopy measurements demonstrated a strong pH effect on amine adsorption and little effect of cyanide in broad agreement with flotation tests and electrochem. impedance measurements.

Minerals Engineering published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Recommanded Product: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Piela, Katarzyna published the artcileMolecular motions contributions to optical nonlinearity of N-benzyl-2-methyl-4-nitroaniline studied by temperature-dependent FT-IR, ¹H NMR spectroscopy and DFT calculations, Computed Properties of 201157-13-3, the publication is Journal of Molecular Structure (2013), 91-97, database is CAplus.

The fourier transform IR (FT-IR) spectra of polycrystalline orthorhombic N-benzyl-2-methyl-4-nitroaniline (BNA) were recorded in the 380-4000 cm^-1 region within the 11-297 K temperature range while the ¹H NMR spin-lattice relaxation time and the second moment of ¹H NMR resonance line were measured in the 145-373 K and 80-400 K temperature range, resp. Above 80 K the Me group rotation is found to be dominant among other motions and leading to a significant reduction of the proton second moment which agrees with proposed models for the rigid structure and for the internal rotations in the BNA crystal such as Me group C₃ rotation, Ph ring rotation and trans-gauche motion of methylene group. Activation energies for the nitro and Me group rotations were exptl. estimated by FT-IR and ¹H NMR, appropriately. For comparison the potential barriers for these two group motions in BNA mol. were calculated by DFT quantum chem. methods. The role of mol. motions in the BNA crystal in the large temperature range is discussed from the point of view of its nonlinear optical properties.

Journal of Molecular Structure published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C14H14N2O2, Computed Properties of 201157-13-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Giguere, Raymond J. published the artcileMicrowave heating in synthesis: preparation of allyldiphenylphosphine oxide, Safety of Allyldiphenylphosphine oxide, the publication is Synthetic Communications (1991), 21(21), 2197-201, database is CAplus.

A new one-pot synthesis of allyldiphenylphosphine oxide (I) has been developed using a tandem S_n2′-Michaelis-Arbuzov sequence. The application of microwave heating lowers the reaction time significantly. Thus, reaction of Ph₂POEt with CH₂:CHCH₂Br in a sealed ampul with microwave irradiation for 2 min affords I in 86% yield. Conventional heating of the reactants for 1 h at 130¡ã afford I in 85% yield.

Synthetic Communications published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Safety of Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Delgado, Esther published the artcileIron carbonyls with bulky thiolate ligands: crystal structures of [F3₂(CO)₆(¦Ì-SC₆H₂ⁱPr₃-2,4,6)₂] and (C₆H₂ⁱPr₃-2,4,6)₂S₂, Product Details of C15H24S, the publication is Inorganica Chimica Acta (1999), 284(1), 14-19, database is CAplus.

The reaction of Fe₃(CO)₁₂ and bulky thiols HSR (R = C₆H₂ⁱPr₃-2,4,6; C₆H₂Me₃-2,4,6) in toluene yielded [Fe₂(CO)₆(¦Ì-SR)₂] (R = C₆H₂ⁱPr₃-2,4,6 (1), C₆H₂Me₃-2,4,6 (2)). The substitution of one carbonyl by the phosphine Ph₂P(CH₂)₂Si(OEt)₃ in complex 1 afforded {Fe₂(CO)₅[Ph₂P(CH₂)₂Si(OEt)₃](¦Ì-SC₆H₂ⁱPr₃-2,4,6)₂} (3). Mononuclear [(¦Ç⁵-C₅H₅)Fe(CO)₂(SC₆H₂ⁱPr₃-2,4,6)] (4) and {(¦Ç⁵-C₅H₅)Fe(CO)[Ph₂P(CH₂)₂Si(OEt)₃](SC₆H₂ⁱPr₃-2,4,6)} (5) also were obtained. Compound 1 was studied by x-ray diffraction and the structure determined reveals a distorted octahedron geometry around each iron atom and confirms the anti arrangement of aryl substituents in the mol. The preparation of thiol HSC₆H₂ⁱPr₃-2,4,6 yielded the disulfide (C₆H₂ⁱPr₃-2,4,6)₂S₂ (6) as a byproduct, whose structure was solved by x-ray diffraction. Crystal data: 1, monoclinic, space group P2₁/a; 6, orthorhombic, space group Pbca.

Inorganica Chimica Acta published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Product Details of C15H24S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Delgado, Esther published the artcileIron carbonyls with bulky thiolate ligands: crystal structures of [Fe₂(CO)₆(¦Ì-SC₆H₂ⁱPr₃-2,4,6)₂] and (C₆H₂ⁱPr₃-2,4,6)₂S₂, Computed Properties of 22693-41-0, the publication is Inorganica Chimica Acta (1999), 284(1), 14-19, database is CAplus.

The reaction of Fe₃(CO)₁₂ and bulky thiols HSR (R = C₆H₂ⁱPr₃-2,4,6; C₆H₂Me₃-2,4,6) in toluene yielded [Fe₂(CO)₆(¦Ì-SR)₂] (R = C₆H₂ⁱPr₃-2,4,6 (1), C₆H₂Me₃-2,4,6 (2)). The substitution of one carbonyl by the phosphine Ph₂P(CH₂)₂Si(OEt)₃ in complex 1 afforded {Fe₂(CO)₅[Ph₂P(CH₂)₂Si(OEt)₃](¦Ì-SC₆H₂ⁱPr₃-2,4,6)₂} (3). Mononuclear [(¦Ç⁵-C₅H₅)Fe(CO)₂(SC₆H₂ⁱPr₃-2,4,6)] (4) and {(¦Ç⁵-C₅H₅)Fe(CO)[Ph₂P(CH₂)₂Si(OEt)₃](SC₆H₂ⁱPr₃-2,4,6)} (5) also were obtained. Compound 1 was studied by x-ray diffraction and the structure determined reveals a distorted octahedron geometry around each iron atom and confirms the anti arrangement of aryl substituents in the mol. The preparation of thiol HSC₆H₂ⁱPr₃-2,4,6 yielded the disulfide (C₆H₂ⁱPr₃-2,4,6)₂S₂ (6) as a byproduct, whose structure was solved by x-ray diffraction. Crystal data: 1, monoclinic, space group P2₁/a; 6, orthorhombic, space group Pbca.

Inorganica Chimica Acta published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Computed Properties of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Roychowdhury, Pritam published the artcileTraceless Benzylic C-H Amination via Bifunctional N-Aminopyridinium Intermediates, Computed Properties of 457-68-1, the publication is Angewandte Chemie, International Edition (2022), 61(28), e202200665, database is CAplus and MEDLINE.

Here, traceless nitrogen activation for C-H amination-which enables application of selective C-H amination chem. to the preparation of diverse N-functionalized products-via sequential benzylic C-H N-aminopyridylation followed by Ni-catalyzed C-N cross-coupling with aryl boronic acids was introduced. Unlike many C-H amination reactions that provide access to protected amines, the current method installs an easily diversifiable synthetic handle that serves as a lynchpin for C-H amination, deaminative N-N functionalization sequences.

Angewandte Chemie, International Edition published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Computed Properties of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Estrada, Martin published the artcileNew cinnamic – N-benzylpiperidine and cinnamic – N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties, Safety of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is European Journal of Medicinal Chemistry (2016), 376-386, database is CAplus and MEDLINE.

Here we describe new families of multi-target directed ligands obtained by linking antioxidant cinnamic-related structures with N-benzylpiperidine (NBP) or N,N-dibenzyl(N-methyl)amine (DBMA) fragments. Resulting hybrids, in addition to their antioxidant and neuroprotective properties against mitochondrial oxidative stress, are active at relevant mol. targets in Alzheimer’s disease, such as cholinesterases (hAChE and hBuChE) and monoamine oxidases (hMAO-A and hMAO-B). Hybrids derived from umbellic – NBP (8), caffeic – NBP (9), and ferulic – DBMA (12) displayed balanced biol. profiles, with IC₅₀s in the low-micromolar and submicromolar range for hChEs and hMAOs, and an antioxidant potency comparable to vitamin E. Moreover, the caffeic – NBP hybrid 9 is able to improve the differentiation of adult SGZ-derived neural stem cells into a neuronal phenotype in vitro.

European Journal of Medicinal Chemistry published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Safety of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia