Tag: M.W=300-350

Lalithamba, H. S. published the artcileEfficient Application of Green Synthesized CeO₂ Nanoparticles for the Preparation of Selenoester Derivatives of Protected Amino Acids and Production of Biodiesel from Annona squamosa Oil, Computed Properties of 71989-31-6, the publication is Journal of Electronic Materials (2022), 51(7), 3650-3659, database is CAplus.

Eco-friendly nano-cerium oxide was synthesized via a simple and efficient solution combustion route using novel aqueous Brahma Kamal leaf extract and characterized by several techniques including powder x-ray diffraction, Fourier transform IR spectroscopy, photoluminescence, UV visible spectroscopy, energy-dispersive x-ray diffraction, SEM, and transmission electron microscopy. The nanomaterial exhibited an excellent catalytic activity in the synthesis of selenoesters of amino acids through the reaction of corresponding amino acyl chloride derivatives with the in situ-generated NaHSe, followed by addition of ¦Á-bromo esters. Wide ranges of unsym. selenoester derivatives of amino acids were afforded with good to excellent yields, and the structures were characterized by high-resolution mass spectroscopy, ¹H and ¹³C NMR spectroscopy, and Fourier transform IR spectroscopy techniques. Furthermore, nano-CeO₂ exhibits tremendous catalytic activity in the production of biodiesel from Annona squamosa oil and achieved around 89% biodiesel yield. The biodiesel produced satisfies ASTM standards

Journal of Electronic Materials published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Computed Properties of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nandy, Saikat published the artcileThe possibility of a fully automated procedure for radiosynthesis of fluorine-18-labeled fluoromisonidazole using a simplified single, neutral alumina column purification procedure, Name: Tetrabutylammonium hydrogencarbonate, the publication is Applied Radiation and Isotopes (2010), 68(10), 1937-1943, database is CAplus and MEDLINE.

A novel fully automated radiosynthesis procedure for [¹⁸F]Fluoromisonidazole using a simple alumina cartridge-column for purification instead of conventionally used semi-preparative HPLC was developed. [¹⁸F]FMISO was prepared via a one-pot, two-step synthesis procedure using a modified nuclear interface synthesis module. Nucleophilic fluorination of the precursor mol. 1-(2′-nitro-1′-imidazolyl)-2-O-tetrahydropyranyl-3-O-toluenesulfonylpropanediol (NITTP) with no-carrier added [¹⁸F]fluoride followed by hydrolysis of the protecting group with 1 M HCl. Purification was carried out using a single neutral alumina cartridge-column instead of semi-preparative HPLC. The maximum overall radiochem. yield obtained was 37.49¡À1.68% with 10 mg NITTP (n=3, without any decay correction) and the total synthesis time was 40¡À1 min. The radiochem. purity was greater than 95% and the product was devoid of other chem. impurities including residual aluminum and acetonitrile. The biodistribution study in fibrosarcoma tumor model showed maximum uptake in tumor, 2 h post injection. Finally, PET/CT imaging studies in normal healthy rabbit, showed clear uptake in the organs involved in the metabolic process of MISO. No bone uptake was observed excluding the presence of free [¹⁸F]fluoride. The reported method can be easily adapted in any com. FDG synthesis module.

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Name: Tetrabutylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Cao, Yan published the artcileCoronene surface for delivery of Favipiravir: Computational approach, Safety of Coronene, the publication is Inorganic Chemistry Communications (2022), 109133, database is CAplus.

Delivery of pharmaceutical compounds has been always an important issue to be solved by appropriate methodologies. In this regard, coronene surface was investigated in this work for possible delivery of favipiravir (FAV) as a well-known drug for medication of COVID-19 pandemic. To this aim, d. functional theory (DFT) calculations were performed to explore surfaces of two representative carbon coronene (C) and boron nitride coronene (BN) models for adsorption of FAV drug. Consequently, complex formations of FAV@C and FAV@BN were examined using the computed mol. and at. parameters. The results indicated that the FAV could interact with both of C and BN surfaces, but with better favorability of FAV@BN complex formation in comparison with FAV@C complex formation. Addnl., mol. orbitlas features indicated that the electronic behavior of FAV@BNC complex could be close to the original FAV in contrast with the results of FAV@CC complex. The evaluated diagrams of d. of states (DOS) showed benefit of the employed models for sensor applications. The obtained features of quantum theory of atoms in mol. (QTAIM) affirmed formations interactions between substances and their strengths. Finally, FAV@BN complex was proposed as proper compound for further investigations of drug delivery processes.

Inorganic Chemistry Communications published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Safety of Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Radhakrishnan, M. published the artcileMolecular structural characterization of superphenalene and supertriphenylene, Application of Coronene, the publication is International Journal of Quantum Chemistry (2022), 122(2), e26818, database is CAplus.

Innovative discovery in bottom-line research and industrial utilization of graphene material has made its mass and low-cost creation an essential advance toward its true applications. This one-mol. thick luminous of carbon accumulates a set of different physico-chem. properties, going from its extraordinary mech. conduct to its uncommon elec. and warm conductivities, which are making graphene a genuine choice to trade numerous customary materials for different applications. Hexabenzocoronene (HBC) is one of the model frameworks for graphene. Because of extremely solid ¦Ð-¦Ð stacking cooperations prompting a columnar plan inside the HBC crystal the subsequent material is as insoluble as graphene. In this paper, we derive the explicit analytic expressions of distance and degree-based topol. indexes of super-polycyclic aromatic compounds with HBC as a base mol., such as superphenalene and supertriphenylene.

International Journal of Quantum Chemistry published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Application of Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Yiming published the artcileTemporal profiles, source analysis, and health risk assessments of parent polycyclic aromatic hydrocarbons (PPAHs) and their derivatives (NPAHs, OPAHs, ClPAHs, and BrPAHs) in PM_2.5 and PM_1.0 from the eastern coastal region of China: Urban coastal area versus coastal background area, Formula: C24H12, the publication is Chemosphere (2022), 133341, database is CAplus and MEDLINE.

The eastern coastal region of China is the area with the highest emission of PAHs in China. Therefore, understanding the sources and health risk of parent polycyclic aromatic hydrocarbons (PPAHs) and their derivatives in eastern coastal cities of China is the main basis for air pollution control. In this study, we measured the concentrations of 18 parent PAHs, 17 nitrated PAHs, 7 oxygenated PAHs, 8 chlorinated PAHs, and 13 brominated PAHs in PM1.0 and PM2.5 samples collected at an urban coastal city site and a coastal background site in 2019. We analyzed the temporal distribution, mol. composition, and sources and performed health risk assessments for both winter and summer samples. The average concentration of the PPAHs and their derivatives (all 63 compounds combined) in the PM_1.0 samples accounted for 75.57% of the PAHs concentration in PM_2.5 samples. The average concentration of PM_2.5– and PM_1.0– bound PPAHs in winter was 114.70 times higher than in summer, and their derivatives was 27.51 times. Both the combined concentrations of the 18 PPAHs and the combined concentrations of the 45 derivatives were higher in the coastal city compared to the background site during the winter (1.90 and 1.48 times, resp.), but they were comparable during the summer. The pos. matrix factorization anal. indicated that the compounds mainly originated from coal/biomass combustion, industrial sources, vehicle emissions, and secondary formation. In addition, the concentration-weighted trajectories model revealed that the PAHs were mainly emitted locally in Shandong Province and surrounding areas, such as Hebei Province, Henan Province, and Bohai Sea. The compounds 1-NPYR, 2+9-BrPHE, 9,10-Cl2PHE, and 1-ClPYR dominantly contributed to the derivatives of TEQ during the winter due to their high concentrations or the high TEFs of these compounds

Chemosphere published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C22H28ClN7O3S, Formula: C24H12.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Shasha published the artcileMerging Late-Stage Diversification with Solid-Phase Peptide Synthesis Enabled by High-Throughput On-Resin Reaction Screening, Related Products of catalysis-chemistry, the publication is ACS Catalysis (2022), 12(5), 3201-3210, database is CAplus.

An integrated workflow is described that combines micromole-scale high-throughput experimentation (HTE) reaction screening and solid-phase peptide synthesis (SPPS) to enable rapid synthetic method development for on-resin peptide diversification. Using this new approach, we have identified several sets of robust Suzuki-Miyaura coupling conditions with complementary scope that collectively display broad coverage with respect to both resin-bound peptide substrates containing aryl halide side chains and (hetero)arylboronic acid coupling partners. We have also demonstrated the utility of this integrated SPPS/chem. diversification method by synthesizing a multidimensional library of diverse peptides in high yields.

ACS Catalysis published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

ChooChuay, Chomsri published the artcileEffects of Agricultural Waste Burning on PM_2.5-Bound Polycyclic Aromatic Hydrocarbons, Carbonaceous Compositions, and Water-Soluble Ionic Species in the Ambient Air of Chiang-Mai, Thailand, Product Details of C24H12, the publication is Polycyclic Aromatic Compounds (2022), 42(3), 749-770, database is CAplus.

PM_2.5 is a widely regarded major air pollutant due to its adverse health effect and intimate relationship with the climate system. This work characterized the chem. components (e.g., organic and elemental C [OC, EC], water soluble ionic species [WSIS], polycyclic aromatic hydrocarbons [PAH]) in PM_2.5 collected over Doi-Inthanon in Chiang-Mai, the highest mountain in Thailand. All samples (n = 50) were collected by MiniVolTM portable air samplers Mar. 2017-Mar. 2018. The average PM_2.5 concentration was 100 ¡À 48.6¦Ìg/m³. The OC:EC ratio was 6.8 ¡À 3.0; the decreasing order of WSIS concentrations was: SO₄^2- > Na⁺ > Ca²⁺ > NH₄⁺ > NO₃^– > K⁺ > Cl^– > NO₂^– > Mg²⁺ > F^–. Total concentrations of nineteen PAH were defined as the sum of Ace, Fl, Phe, Ant, Fluo, Pyr, B[a]A, Chry, B[b]F, B[k]F, B[a]F, B[e]P, B[a]P, Per, Ind, B[g,h,i]P, D[a,h]A, Cor, and D[a,e]P. The total PAH concentration 2.361 ¡À 2.154¦Ìg/m³. Principal component anal. (PCA) highlighted the importance of vehicle exhaust, biomass burning, diesel emissions, sea-salt aerosols, and fertilizer volatilization as the five dominant potential sources, accounting for 51.6, 16.2, 10.6, 5.20, and 3.70% of total variance, resp. The remaining 12.7% variance is associated with unidentified local and regional sources, e.g., incinerators, joss paper/incense burning, domestic cooking. PCA source estimation results underlined the importance of vehicle exhaust as the major PM_2.5 contributor in ambient air over Don-Inthanon, Chiang-Mai Province. It is crucial to emphasize the effect of agricultural waste burning, fossil fuel combustion, coal combustion, and forest fires on OC, EC, and WSIS concentration variations was not negligible.

Polycyclic Aromatic Compounds published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Product Details of C24H12.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xu, Min published the artcileTrophic niche partitioning of five sympatric shark species in the tropical eastern Pacific Ocean revealed by multi-tissue fatty acid analysis, Recommanded Product: Docosahexaenoic Acid, the publication is Environmental Research (2022), 214(Part_1), 113828, database is CAplus and MEDLINE.

Fatty acid (FA) anal. of consumer tissues has recently shown utility in drawing further inferences about trophic niche dynamics of marine predators such as sharks. In this study, we examined liver, plasma, and muscle FAs in five coexisting pelagic sharks (blue (Prionace glauca), silky (Carcharhinus falciformis), bigeye thresher (Alopias superciliosus), pelagic thresher (Alopias pelagicus), and smooth hammerhead (Sphyrna zygaena)) inhabiting the tropical eastern Pacific Ocean. Results showed complex inter- and intra-individual and tissue variation among the five shark species. Based on multivariate anal. of the muscle FAs, P. glauca and C. falciformis have the largest FA niche widths, indicating diverse feeding habits or habitat isolation, whereas A. pelagicus and S. zygaena occupied a narrower niche width, reflecting increased trophic specialization. High percentages of muscle FA niche overlap indicated strong resource competition between S.zygaena and C. falciformis and a degree of dietary isolation by P. glauca. Interpretations of feeding ecol. differed based on the anal. of plasma FAs, which could be attributed to higher dietary FA turnover rates. The liver was deemed unsuitable to examine FA niche metrics based on high and unexplained intra-specific variance in liver FAs as well as the unique lipid metabolism in chondrichthyans. Overall, our multi-tissue approach revealed the magnitude of potential competitive interactions among coexisting tropical shark species. It also expanded our understanding of inter-tissue variability and best practices when using FA anal. to estimate trophic niche metrics of sharks.

Environmental Research published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C19H21N3O3S, Recommanded Product: Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Beyerlein, Friederike published the artcileAutomated synthesis and purification of [¹⁸F]fluoro-[di-deutero]methyl tosylate, Related Products of catalysis-chemistry, the publication is Journal of Labelled Compounds and Radiopharmaceuticals (2013), 56(7), 360-363, database is CAplus and MEDLINE.

Automated synthetic procedures of [¹⁸F]fluoro-[di-deutero]methyl tosylate on a GE TRACERlab FX F-N module and a non-com. synthesis module have been developed. The syntheses included azeotropic drying of the [¹⁸F]fluoride, nucleophilic ¹⁸F-fluorination of bis(tosyloxy)-[di-deutero]methane, HPLC purification and subsequent formulation of the synthesized [¹⁸F]fluoro-[di-deutero]methyl tosylate (d₂-[¹⁸F]FMT) in organic solvents. Automation shortened the total synthesis time to 50 min, resulting in an average radiochem. yield of about 50% and high radiochem. purity (>98%). The possible application of this procedure to com. available synthesis modules might be of significance for the production of deuterated ¹⁸F-fluoromethylated imaging probes in the future. Copyright 2013 John Wiley & Sons, Ltd.

Journal of Labelled Compounds and Radiopharmaceuticals published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Todorov, Petar published the artcileSynthesis and characterization of new 5,5¡ä-dimethyl- and 5,5¡ä-diphenylhydantoin-conjugated hemorphin derivatives designed as potential anticonvulsant agents, Application In Synthesis of 71989-31-6, the publication is New Journal of Chemistry (2022), 46(5), 2198-2217, database is CAplus.

Herein, the synthesis and characterization of some novel N-modified hybrid analogs of hemorphins containing a C-5 substituted hydantoin residue as potential anticonvulsants and for the blockade of sodium channels are presented. Their structure-property relationships are highlighted by electrochem. and Fourier transform IR spectroscopy (FT-IR) anal. methods. The lipophilicity and mol. docking of voltage-gated sodium channels were also determined The new series of 5,5-dimethyl- and 5,5-diphenylhydantoin-conjugated hemorphin derivatives were obtained as C-terminal amides via solid-phase peptide synthesis, an Fmoc-strategy using 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate (TBTU). The anticonvulsant activity of the hybrid-peptides (0.25, 0.5 and 1 ¦Ìg) was tested by maximal electroshock (MES) and 6 Hz psychomotor seizure tests using male ICR mice. None of the compounds tested showed neurotoxicity in the rotarod test. The reference drug phenytoin was used as a pos. control. The most active compound Ph-5 showed 100% efficacy against the 6 Hz-induced psychomotor seizures at a dose of 1.0 ¦Ìg and tonic seizures in the MES test at a lower dose of 0.5 ¦Ìg. This analog of VV-hemorphin-5 contained a 5,5-diphenylhydantoin residue at the N-terminus and a hydrophobic Val-Val-Tyr-Pro-Trp-Thr-Gln-CONH₂ amino acid sequence of the peptide mol. The quant. data for the 6 Hz test demonstrated that the peptide Ph-5 exhibited a median ED (ED50) value of 0.358 ¦Ìg and PI >13.97, and ED50 of 0.25 ¦Ìg and PI >20.35 in the MES test, resp. Results from the docking study suggest that the neuropeptide Ph-5 is a potent inhibitor of sodium channels, and blockade of voltage-gated sodium channels could be the mechanism of action of the hybrid-peptide derivatives with anticonvulsant activity.

New Journal of Chemistry published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C7H13NO2, Application In Synthesis of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia