Tag: M.W=300-350

Jafari, A. published the artcileElectronic absorption spectra of cresyl violet acetate in anisotropic and isotropic solvents, Safety of 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2007), 66A(3), 717-725, database is CAplus and MEDLINE.

The isotropic and anisotropic solvation characteristics of cresyl violet acetate (CVA) were studied in isotropic liquid solutions and in polar nematic matrixes as a function of the solvent type and concentration The interaction of the ionic dye with the anisotropic surrounding and with that of the isotropic solvents was studied and compared. Probably the nematic liquid crystalline solvents might create stronger solvation than the isotropic solvents. The spectral shifts were correlated by the solvent permittivity and Kamlet-Taft parameters. The polarized absorption spectra of cresyl violet acetate were measured at 400-800 nm and the dichroic ratio R and degree of anisotropy S of this dye in the liquid crystalline host determined

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Safety of 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Narode, Hanuman published the artcileVanillin containing 9H-fluoren sulfone scaffolds: Synthesis, biological evaluation and molecular docking study, Product Details of C20H19NO4, the publication is Results in Chemistry (2022), 100269, database is CAplus.

Vanillin containing 9H-fluoren sulfone scaffolds I [R = Fmoc-Gly, Fmoc-Pro, Fmoc-Phe, etc.] were prepared by coupling a sulfone amine with carboxylic acid group of amino acids in presence of peptide coupling reagent hexafluorophosphate benzotriazole tetra-Me uronium (HBTU). All eight compounds I synthesized vanillin containing 9H-fluoren sulfone scaffolds were evaluated for their biol. activities, namely, antibacterial, antifungal and antimalarial. The antibacterial evaluation revealed that compounds I [R = Fmoc-Ala, Fmoc-Ser(t-Bu), Fmoc-Pro, Fmoc-Leu, Fmoc-D-Val, Fmoc-Met] exhibited potency against tested pathogenic bacteria, especially against Staphylococcus aureus. Compounds I [R = Fmoc-Ala, Fmoc-Val, Fmoc-Phe] manifested considerable antifungal activities against Candida albicans, Aspergillus niger and A. clavatus. Moreover, the antimalarial result demonstrated excellent antimalarial activities for compounds I [R = Fmoc-Ala, Fmoc-Val] against Plasmodium falciparum with IC₅₀ less than the standard quinine. Further, mol. docking study was performed to find mol. level interaction of compounds with malarial drug target enzyme P. falciparum dihydrofolate reductase-thymidylate synthase (pfdher-ts). Interestingly, for all tested sulfone scaffolds the docking energy was found between -8.6 to -10.6 kcal/mol, which was higher than both of the standard drugs’ (quinine and chloroquine) docking energy, i.e. -8.4 and -6.9, resp. The results of this study confirmed the importance of the sulfone class of compounds in the treatment of parasitic infections and microbial infections.

Results in Chemistry published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Product Details of C20H19NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zheng, Hongli published the artcileDocosahexaenoic acid production of the marine microalga Isochrysis galbana cultivated on renewable substrates from food processing waste under CO₂ enrichment, Quality Control of 6217-54-5, the publication is Science of the Total Environment (2022), 157654, database is CAplus and MEDLINE.

Leftover dough is a starch-rich food processing waste of Chinese steamed bread. Leftover dough hydrolyzates enriched with glucose and amino acids were used to cultivate the marine microalga Isochrysis galbana to produce docosahexaenoic acid (DHA) under CO₂ enrichment. Isochrysis galbana could use mixed carbon sources (CO₂, glucose, and amino acids) synchronously to grow and accumulate DHA. Cell growth, the uptake of glucose and amino acids, and DHA production were significantly affected by CO₂ enrichment. The maximum biomass concentration of 3.85 g L^-1 was achieved with 3% CO₂. And the maximum DHA yield was 65.5 mg L^-1 d^-1. To enhance DHA production, a two-stage cultivation strategy was successfully developed by this work. The maximum DHA yield of the two-stage culture was elevated by 2.3-fold. It is feasible to produce DHA by Isochrysis galbana using leftover dough under CO₂ enrichment.

Science of the Total Environment published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C7H10O4, Quality Control of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Di Mauro, Chiara published the artcileKinetical Study, Thermo-Mechanical Characteristics and Recyclability of Epoxidized Camelina Oil Cured with Antagonist Structure (Aliphatic/Aromatic) or Functionality (Acid/Amine) Hardeners, Product Details of C14H10O4S2, the publication is Polymers (Basel, Switzerland) (2021), 13(15), 2503, database is CAplus and MEDLINE.

In an attempt to prepare sustainable epoxy thermosets, this study introduces for the first time the idea to use antagonist structures (aromatic/aliphatic) or functionalities (acid/amine) as hardeners to produce reprocessable resins based on epoxidized camelina oil (ECMO). Two kinds of mixtures were tested: one combines aromatic/aliphatic dicarboxylic acids: 2,2-dithiodibenzoic acid (DTBA) and 3,3-dithiodipropionic acid (DTDA); another is the combination of two aromatic structures with acid/amine functionality: DTBA and 4-aminophenyl disulfide (4-AFD). DSC and FT-IR analyses were used as methods to analyze the curing reaction of ECMO with the hardeners. It was found that the thermosets obtained with the dual crosslinked mechanism needed reduced curing temperatures and reprocessing protocols compared to the individual crosslinked thermosets. Thanks to the contribution of disulfide bonds in the network topol., the obtained thermosets showed recycling ability. The final thermomech. properties of the virgin and mech. reprocessed materials were analyzed by DMA and TGA. The obtained thermosets range from elastomeric to rigid materials. As an example, the ECMO/DTBA₇₀4-AFD₃₀ virgin or reprocessed thermosets have tan ¦Ä values reaching 82-83¡ãC. The study also investigates the chem. recycling and the solvent resistance of these vitrimer-like materials.

Polymers (Basel, Switzerland) published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Product Details of C14H10O4S2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Dawei published the artcileTemplation and Concentration Drive Conversion Between a Fe^II₁₂L₁₂ Pseudoicosahedron, a Fe^II₄L₄ Tetrahedron, and a Fe^II₂L₃ Helicate, Safety of Coronene, the publication is Journal of the American Chemical Society (2022), 144(3), 1106-1112, database is CAplus and MEDLINE.

authors report the construction of three structurally distinct self-assembled architectures: Fe^II₁₂L₁₂ pseudoicosahedron 1, Fe^II₂L₃ helicate 2, and Fe^II₄L₄ tetrahedron 3, formed from a single triazatriangulenium subcomponent A under different reaction conditions. Pseudoicosahedral capsule 1 is the largest formed through subcomponent self-assembly to date, with an outer-sphere diameter of 5.4 nm and a cavity volume of 15 nm³. The outcome of self-assembly depended upon concentration, where the formation of pseudoicosahedron 1 was favored at higher concentrations, while helicate 2 exclusively formed at lower concentrations The conversion of pseudoicosahedron 1 or helicate 2 into tetrahedron 3 occurred following the addition of a CB₁₁H₁₂^– or B₁₂F₁₂^2- template.

Journal of the American Chemical Society published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C12H16O3, Safety of Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chaudhuri, Dipankar published the artcileChemical synthesis of a potent antimicrobial peptide Murepavadin using a tandem native chemical ligation/desulfurization reaction, COA of Formula: C20H19NO4, the publication is Journal of Organic Chemistry (2021), 86(21), 15242-15246, database is CAplus and MEDLINE.

Classical approaches for the backbone cyclization of polypeptides require conditions that may compromise the chirality of the C-terminal residue during the activation step of the cyclization reaction. Here, we describe an efficient epimerization-free approach for the Fmoc-based (Fmoc = 9-fluorenyl-methoxycarbonyl) synthesis of murepavadin using intramol. native chem. ligation in combination with a concomitant desulfurization reaction. Using this approach, bioactive murepavadin was produced in a good yield in two steps. The synthetic peptide antibiotic showed potent activity against different clin. isolates of P. aeruginosa. This approach can be easily adapted for the production of murepavadin analogs and other backbone-cyclized peptides.

Journal of Organic Chemistry published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, COA of Formula: C20H19NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wan, Qiong-Qiong published the artcileA Cresyl Violet-Based Fluorescent Off-On Probe for the Detection and Imaging of Hypoxia and Nitroreductase in Living Organisms, Application In Synthesis of 10510-54-0, the publication is Chemistry – An Asian Journal (2014), 9(8), 2058-2062, database is CAplus and MEDLINE.

A new cresyl violet-based fluorescent off-on probe has been developed through a one-step synthesis for the detection of nitroreductase (NTR) and hypoxia. The detection mechanism is based on the NTR-catalyzed reduction of the probe to cresyl violet, accompanied with a large fluorescence enhancement at a long wavelength of 625 nm. The probe can detect NTR in aqueous solution with high selectivity and sensitivity, and the detection limit is 1 ng mL^-1 NTR. Most importantly, the probe has been successfully used to image not only NTR and hypoxia in living cells, but also the distribution of NTR in zebrafish in vivo.

Chemistry – An Asian Journal published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C15H14Cl2S2, Application In Synthesis of 10510-54-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ema, Tadashi published the artcileQuaternary ammonium hydroxide as a metal-free and halogen-free catalyst for the synthesis of cyclic carbonates from epoxides and carbon dioxide, Quality Control of 17351-62-1, the publication is Catalysis Science & Technology (2015), 5(4), 2314-2321, database is CAplus.

Tetrabutylammonium hydroxide (TBAH) and other quaternary ammonium hydroxides catalyzed the cycloaddition of CO₂ to epoxides under solvent-free conditions to give cyclic carbonates. When TBAH was exposed to CO₂, TBAH was converted into tetrabutylammonium bicarbonate (TBABC), which was a catalytically active species. A D-labeled epoxide and an optically active epoxide were used to study the reaction mechanism, which invoked three plausible pathways. Among them, path A seemed to be predominant; the bicarbonate ion of TBABC attacks the less hindered C atom of the epoxide to generate a ring-opened alkoxide intermediate, which adds to CO₂ to give a carbonate ion, and the subsequent cyclization yields a cyclic carbonate. D. functional theory (DFT) calculations successfully delineated the potential energy profile for each reaction pathway, among which path A was the lowest-energy pathway in accordance with the exptl. results. The tetrabutylammonium (TBA) cation carries the pos. charges on the H atoms, but not on the central N atom, and the pos. charged H atoms close to the central N atom form an anion-binding site capable of stabilizing various anionic transition states and intermediates.

Catalysis Science & Technology published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Quality Control of 17351-62-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Min-Chen published the artcileMultigenerational inspections of environmental thermal perturbations promote metabolic trade-offs in developmental stages of tropical fish, COA of Formula: C22H32O2, the publication is Environmental Pollution (Oxford, United Kingdom) (2022), 119605, database is CAplus and MEDLINE.

Global warming both reduces global temperature variance and increases the frequency of extreme weather events. In response to these ambient perturbations, animals may be subject to trans- or intra-generational phenotype modifications that help to maintain homeostasis and fitness. Here, we show how temperature-associated transgenerational plasticity in tilapia affects metabolic trade-offs during developmental stages under a global warming scenario. Tropical tilapia reared at a stable temperature of 27¡ãC for a decade were divided into two temperature-experience groups for four generations of breeding. Each generation of one group was exposed to a single 15¡ãC cold-shock experience during its lifetime (cold-experienced CE group), and the other group was kept stably at 27¡ãC throughout their lifetimes (cold-naive CN group). The offspring at early life stages from the CE and CN tilapia were then assessed by metabolomics-based profiling, and the results implied that parental cold-experience might affect energy provision during reproduction Furthermore, at early life stages, progeny may be endowed with metabolic traits that help the animals cope with ambient temperature perturbations. This study also applied the feature rescaling and Uniform Manifold Approximation and Projection (UMAP) to visualize metabolic dynamics, and the result could effectively decompose the complex omic-based datasets to represent the energy trade-off variability. For example, the carbohydrate to free amino acid conversion and enhanced compensatory features appeared to be hypothermic-responsive traits. These multigenerational metabolic effects suggest that the tropical ectothermic tilapia may exhibit transgenerational phenotype plasticity, which could optimize energy allocation under ambient temperature challenges. Knowledge about such metabolism-related transgenerational plasticity effects in ectothermic aquatic species may allow us to better predict how adaptive mechanisms will affect fish populations in a climate with narrow temperature variation and frequent extreme weather events.

Environmental Pollution (Oxford, United Kingdom) published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C10H16Br3N, COA of Formula: C22H32O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yang, Chu-Ting published the artcileRoom-Temperature Copper-Catalyzed Carbon-Nitrogen Coupling of Aryl Iodides and Bromides Promoted by Organic Ionic Bases, Safety of Tetrabutylammonium hydrogencarbonate, the publication is Angewandte Chemie, International Edition (2009), 48(40), 7398-7401, S7398/1-S7398/182, database is CAplus and MEDLINE.

Novel room-temperature Cu-catalyzed C-N couplings of aryl iodides and bromides with amines promoted by organic ionic bases are reported. E.g., in presence of L-proline, tetrabutylammonium adipate, and CuI, coupling of 2-IC₆H₄CO₂H with BnNH₂ gave 89% 2-BnNHC₆H₄CO₂H. Good solubility alone does not explain the performance of the organic ionic bases. Conductivity measurements indicate that the usefulness of organic ionic bases may be attributed to their good ionization ability in organic solvents.

Angewandte Chemie, International Edition published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H18N3NaO3S, Safety of Tetrabutylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia