Tag: M.W=300-350

Wu, Weida published the artcileCharacterization and identification of pork flavor compounds and their precursors in Chinese indigenous pig breeds by volatile profiling and multivariate analysis, Category: catalysis-chemistry, the publication is Food Chemistry (2022), 132543, database is CAplus and MEDLINE.

Chinese indigenous pigs are favored for their rich flavor, which is generated through complex reactions involving lipid-oxidation-related flavor precursors. In this research, we characterized the aroma compounds and fatty acids of representative Chinese pig breeds by gas chromatog.-olfactometry-mass spectrometry (GC-O-MS) and GC-ion mobility spectrometry (GC-IMS) with multivariate anal. A total of 79 volatile compounds were identified, among which 15 compounds were selected as odorants in pork. According to multivariate statistical anal., some odorants, including hexanal, 1-octen-3-ol, 2,3-octanedione, (E, E)-2,4-decadienal and dodecanal could be discriminative compounds explaining breed-originated differences in flavor profiles. As confirmed by partial least squares regression (PLS-R), some fatty acids, including C18:1n9c, C22:6n3 and C18:3n3, were major precursors for the formation of rich flavor in indigenous pig breeds. These results revealed that fatty acids and volatile compounds were breed-dependent, and the differences in flavor were related to the variance in the fatty acid content.

Food Chemistry published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C8H11BO2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Yan published the artcileThermochemical Sulfate Reduction by Pyrobitumen: Review and Experiments, Product Details of C24H12, the publication is ACS Earth and Space Chemistry (2022), 6(2), 308-321, database is CAplus.

A review. It has remained controversial throughout the last 3 decades whether highly mature solid bitumen derived from petroleum degradation can engage in thermochem. sulfate reduction (TSR)-an organic-inorganic interaction that occurs in sedimentary basins. To study the kinetic characteristics of thermal sulfate reduction by thermogenic pyrobitumen, hydropyrolysis experiments with Mg sulfate (MgSO₄) and a model compound, coronene (C₂₄H₁₂), were performed at 300-500¡ã under controlled laboratory conditions. Detectable amounts of H₂S from the designed simulation system were formed at a threshold temperature of 400¡ã. Thermodynamically, coronene-initiated sulfate reduction is an exothermic process at 100-220¡ã with the reaction heat of 221.0-248.3 kJ/mol hydrocarbon. TSR of coronene is characterized by a 1st-order reaction with an apparent activation energy of 193.0 kJ/mol. Interactions between C₂₄H₁₂ and MgSO₄ are kinetically categorized as a slow TSR system because the high stability of coronene restricts the formation rate of H₂S gas relative to rapid TSR systems containing C₂₊ hydrocarbons. When extrapolated to the temperature range of typical oil and gas reservoirs (100-200¡ã), the reaction rate of TSR by coronene is slightly higher than that of TSR involving methane, gypsum, and MgCl₂ solutions Depletion of some organic carbons by TSR may contribute to the increase of S/C ratios in the mol. structure of thermogenic pyrobitumen. In deep carbonate reservoirs of methane-dominated TSR, hydrothermal reduction of sulfates by thermogenic pyrobitumen most likely occurs as a less well-recognized geochem. process.

ACS Earth and Space Chemistry published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Product Details of C24H12.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhu, Guizhi published the artcileCombinatorial Screening of DNA Aptamers for Molecular Imaging of HER2 in Cancer, COA of Formula: C17H37NO3, the publication is Bioconjugate Chemistry (2017), 28(4), 1068-1075, database is CAplus and MEDLINE.

HER2, a cell membrane protein overexpressed in many types of cancers, is correlated with poor diagnosis, suboptimal treatment outcome, and low survival rate. Multiple HER2-targeted drugs have been developed for the treatment of HER2-overexpressing tumor, which can in turn down-regulate HER2 expression. It is thus significant to profile HER2 expression for cancer prognosis, patient stratification, and monitoring therapy response. Aptamers, a class of single-stranded DNA/RNA (ssDNA/ssRNA) ligands, are promising for mol. biomarker imaging. Aptamers typically have strong binding affinity, high selectivity, batch-to-batch reproducibility, and low toxicity, and systemically injected aptamers often have high tumor-to-background ratio within a short time. However, current aptamers have been mostly screened in vitro, and these aptamers may lose binding ability in vivo due to conformational change under physiol. environments. Here, a DNA library was combinatorially screened in vitro and in vivo, to select HER2-targeting DNA aptamers, termed Heraptamers, and labeled with ¹⁸F for positron emission tomog. (PET) imaging of HER2 in ovarian cancer. Specifically, using systematic evolution of ligands by exponential enrichment (SELEX), Heraptamer candidates were first selected and validated in vitro using HER2 extracellular domain (ECD) and HER2-pos. SKOV3 cancer cells; then, aptamer candidates were modified with alkyne, radiolabeled with ¹⁸F using azide-functionalized precursors by click chem., and screened in SKOV3-tumor-bearing mice using PET. Two aptamers, Heraptamer1 and Heraptamer2, reached high tumor uptake ratios within as short as 1 h. At 1.5 h post injection, the tumor uptake ratio of these two aptamers was up to 0.5%ID/g (injection dose/g tissue), with tumor-to-muscle ratio of 4.55 ¡À 1.63 in SKOV3 tumor. In contrast, these aptamers have low uptake ratios in control MDA-MB-231 tumors. These preclin. studies showed that Heraptamers are promising for specific HER2 imaging.

Bioconjugate Chemistry published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C12H14S, COA of Formula: C17H37NO3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Qi, Xin published the artcileBio-based, robust, shape memory, self-healing and recyclable elastomers based on a semi-interpenetrating dynamic network, Related Products of catalysis-chemistry, the publication is Journal of Materials Chemistry A: Materials for Energy and Sustainability (2021), 9(45), 25399-25407, database is CAplus.

Fabricating materials with a combination of high toughness, and self-healing, shape memory and reprocessing properties, especially derived from renewable precursors, remains a challenge. Herein, we demonstrate a simple strategy to prepare a multifunctional elastomer based on a semi-interpenetrating dynamic network (semi-IDN) by using sustainable Eucommia ulmoides gum (EUG) as a raw material. The elastomer possessed high stretchability (~876%) and high tensile strength (~12.1 MPa) as well as good self-healing, solid plasticity and shape memory properties. Moreover, it can not only be reprocessed by hot pressing (tensile strength remains 92% after three times of reprocessing), but can also be recycled by dissolving with little effect on the structure and properties. In addition, a flexible electronic device is prepared by spraying hydroxylated multiwalled carbon nanotubes (MWCNTs-OH) on its surface, which exhibited good self-healing of elec. conductivity after damage. The semi-IDN concept provides a new pathway to prepare reprocessed materials, and the as-prepared elastomers have broad application prospects in new generation green rubber and flexible wearable devices.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Zhiyong published the artcileOPEN ACCESS sources and health risks of PM 2.5 -bound PAHs in a small city along with the “clean heating” policy, Recommanded Product: Coronene, the publication is Aerosol and Air Quality Research (2022), 22(7), 220162, database is CAplus.

Levels, composition, and sources of PM_2.5-bound polycyclic aromatic hydrocarbons (PAHs) vary significantly along with the “Clean Heating” (CH) policy in Beijing-Tianjin-Hebei (BTH) region, whereas the PAH characteristics with CH in small cities still remain unclear. A field observation was conducted in Baoding City, a small city within the BTH region, in winter of 2019 covering both the pre-heating season (PHS) and the heating season (HS). From the PHS to the HS, the mean concentrations for both PM_2.5 and ¡Æ18PAHs increased from 69.1 to 125.0 ¦Ìg m^-3 and from 8.09 to 26.2 ng m^-3 due to the heating activities. The far lower PAHs in this study than those of small cities before CH implementation indicated the CH effectiveness. Higher diagnostic ratios (DRs) of FA/(FA + PY), BaA/(BaA + CHR), and IP/(IP + BgP) in the HS were in agreement with the increased coal/biomass usage. Pos. matrix factorization (PMF) demonstrated that biomass/natural-gas burning (BNGB) contributed most to PAHs of 36.9% in the HS, the increased natural gas (NG) usage for heating should be responsible for this contribution due to the policies of biomass-burning prohibition and ¡äCoal to Gas¡ä. Coal combustion (CC) shares increased by 152% in the HS despite the ¡äCoal Banning¡ä project. Again, the medium-mol.-weight PAHs (MMW-PAHs) increased most by 400% in the HS, evidencing the increased impacts of fossil-fuel consumptions. As an indicator for carcinogenic risk, BaP increased from 0.937 in the PHS to 1.29 ng m^-3 in the HS. Furthermore, the incremental lifetime cancer risks (ILCR) and BaP equivalent concentrations (BaPeq) increased in the HS. The mean ILCR values of 1.15 x 10^-6 for adults in the HS exceeded the threshold of 1 x 10^-6 , while they were lower than 1 x 10^-6 for children in both the PHS and the HS, and adults in the PHS due to the CH pos. effects.

Aerosol and Air Quality Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Recommanded Product: Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Akin, Ummuhan published the artcileDielectric properties of coronene film deposited onto silicon substrate by spin coating for optoelectronic applications, Related Products of catalysis-chemistry, the publication is Silicon (2022), 14(5), 2201-2209, database is CAplus.

To determine the elec. modulus, dielec. properties, and ac conductivity of coronene semiconductor layer, the have produced Al/Coronene/n-Si structure by using the thermally evaporation and spin coating method. The variation of dielec. constant (¦Å’), dielec. imaginary part (¦Å”), tangent loss (tan¦Ä), elec. modulus (M‘ and M”), and AC elec. conductivity (¦Ò_ac) with voltage and frequency of Coronene semiconductor layer have been investigated in the frequency range of 1 kHz – 1 MHz and at the selected voltages (0.0-0.4 V with steps 0.02 V). It is found that the ¦Å’ and ¦Å” values decrease with increasing frequency while an increase is observed in tan¦Ä, ¦Ò_ac, and the real (M‘) and the imaginary (M”) of the elec. modulus. The ¦Å’, & ¦Å” tan¦Ä, ¦Ò_ac, M‘ and M” values have been determined as 6.53, 8.58, 1.31, 0.0477 S/cm, 0.0561 and 0.0477 for 1 kHz and 0.0046, 0.129, 2.78, 7.17 S/cm, 0.278, and 7.74 for 1 MHz at 0.0 V, resp.

Silicon published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Song, Dongying published the artcileEffects of faba bean (Vicia faba L.) on fillet quality of Yellow River carp (Cyprinus carpio) via the oxidative stress response, Product Details of C22H32O2, the publication is Food Chemistry (2022), 132953, database is CAplus and MEDLINE.

In order to further explain the fillet texture improvement of Yellow River carp (Cyprinus carpio) fed with faba bean (Vicia faba L.), a three-month rearing trial was conducted to investigate fatty acid composition, antioxidant capacity, myofiber development, collagen deposition and transcriptome in white muscle of two farmed carp groups (One was fed only faba bean, the other was fed com. diet). As a strong oxidant, faba bean changed fatty acids composition in white muscle, especially DHA and EPA, up-regulated the levels of reactive oxygen species (ROS) and down-regulated major antioxidant enzyme activities in the hepatopancreas and white muscle. Through the anal. of transcriptome and subsequent verification anal., we speculated that the increase of ROS led to the decrease of myofiber diameter and collagen metabolism This study provides a theor. basis for further understanding the regulation of faba bean on fillet texture characteristic of Yellow River carp.

Food Chemistry published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C15H14N2, Product Details of C22H32O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Longo, Beatrice published the artcileDesign, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers, Application In Synthesis of 1466420-02-9, the publication is Bioconjugate Chemistry (2020), 31(9), 2201-2210, database is CAplus and MEDLINE.

The tetrazine/trans cyclooctene (TCO) inverse-electron-demand Diels-Alder (IEDDA) reaction is the fastest bioorthogonal ”click” ligation process reported to date. In this context, TCO reagents have found widespread applications, however their availability and structural diversity is still somewhat limited, due to challenges connected with their synthesis and structural modification. To address this issue, a novel strategy for the conjugation of TCO derivatives to a biomol. was developed, which allows for the creation of greater structural diversity from a single precursor mol., i.e. trans,trans-1,5-cyclooctadiene [(E,E)-COD], whose preparation requires standard laboratory equipment and readily available reagents. This two-step strategy relies on the use of new bifunctional TCO-linkers (3aSR,9aSR,E)-I (R = 2-[(2,5-dioxopyrrolidin-1-yl)oxy]-2-oxoethyl, 2-[2-(2-(2-[(4-nitrophenoxycarbonyl)oxy]ethoxy)ethoxy)ethoxy]ethyl, (4-([(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl)phenyl)methyl, etc.) for IEDDA reactions, which can be synthesized via 1,3-dipolar cycloaddition of (E,E)-COD with different azido-spacers RN₃ carrying an electrophilic function (NHS-ester, N-succinimidyl carbonate, p-nitrophenyl-carbonate, maleimide) in the ¦Ø-position. Following bioconjugation of these electrophilic linkers to the nucleophilic residue (cysteine or lysine) of a protein (step 1), the resulting TCO-decorated constructs can be subjected to a IEDDA reaction with tetrazines functionalized with fluorescent or near IR (NIR) tags (step 2). This strategy to label bovine serum albumin with the TCO-linker (3aSR,9aSR,E)-I (II, R = 14-[(2,5-dioxopyrrolidin-1-yl)oxy]-14-oxo-3,6,9,12-tetraoxatetradecan-1-yl) and to subsequently react it in a cell lysate with the fluorescein-isothiocyanate (FITC)-derived tetrazine II was successfully used. The same strategy was then used to label the bacterial wall of gram-pos. S. aureus showing the potential of these linkers for live-cell imaging. Finally, the impact of structural differences of the linkers upon the stability of the bioorthogonal constructs was determined The compounds for stability studies were prepared by conjugation of TCO-linkers (3aSR,9aSR,E)-I (R = (4-([(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl)phenyl)methyl, 2-[2-(2-(2-[(4-nitrophenoxycarbonyl)oxy]ethoxy)ethoxy)ethoxy]ethyl, II) to mAbs, such as Rituximab and Obinutuzumab, and subsequent labeling with a reactive Cy3-functionalized tetrazine.

Bioconjugate Chemistry published new progress about 1466420-02-9. 1466420-02-9 belongs to catalysis-chemistry, auxiliary class Copper-Free Click Chemistry,Tetrazine, name is (4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl)methanamine trifluoroacetic acid, and the molecular formula is C12H12F3N5O2, Application In Synthesis of 1466420-02-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yuasa, M. published the artcileComputer-controlled synthesis of [¹⁸F]FDG by the tetrabutylammonium method: achievement of high yield, purity, reproducibility, reliability, and safety, HPLC of Formula: 17351-62-1, the publication is Applied Radiation and Isotopes (1997), 48(2), 201-205, database is CAplus.

The authors constructed a computer-controlled apparatus of no-carrier-added [¹⁸F]fluorodeoxyglucose ([¹⁸F]FDG) synthesis for routine clin. use. High yield, high reproducibility, and high quality of the product were achieved. The main step of the reaction is nucleophilic fluorination of the synthetic precursor, acetylated mannose triflate, with an activator, tetrabutylammonium bicarbonate. A biol. high quality medicinal environment (sterile and pyrogen-free) was achieved by employment of an inherently pyrodestructive chem. step within the process line and the use of pyrogen-free medical goods and heat-sterilized glassware. [¹⁸F]FDG was obtained in 70 min after EOB with a radiochem. yield of 57.7 ¡À 5.7% (decay corrected) and with radiochem. purity of > 99%.

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C4H6O3, HPLC of Formula: 17351-62-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chae, Weon-Sik published the artcileBimodal porous gold opals for molecular sensing, Recommanded Product: 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, the publication is Electronic Materials Letters (2013), 9(6), 783-786, database is CAplus.

We have fabricated bimodal porous gold skeletons by double-templating routes using poly(styrene) colloidal opals as templates. The fabricated gold skeletons show a bimodal pore-size distribution, with small pores within spheres and large pores between spheres. The templated bimodal porous gold skeletons were applied in Raman scattering experiments to study sensing efficiency for probe mols. We found that the bimodal porous gold skeletons showed obvious enhancement of Raman scattering signals vs. that of the unimodal porous gold which only has interstitial pores of several hundred nanometers.

Electronic Materials Letters published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Recommanded Product: 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia