Tag: M.W=300-350

Yuan, Ronghui published the artcileCharacterization of interfacial behaviour of ortho-positioned diaryl disulfide on silver substrates by surface-enhanced Raman scattering and electroreduction, Related Products of catalysis-chemistry, the publication is Materials Chemistry and Physics (2019), 121726, database is CAplus.

The interfacial behavior of ortho-positioned diaryl disulfide on activated silver substrates was characterized with surface-enhanced Raman scattering and electroreduction After the fracture of the disulfide bond, the diaryl disulfides interacted with Ag to form self-assembled monolayers. The peak intensity of benzene ring deformation and pH-dependence presented two types of linear relationships. The probe mol. at pH 11.5 was used to estimate the Raman enhancement factor of silver substrates. Also, the alk. media were favorable for the active intermediates of ortho-positioned diaryl disulfide to interact on the liquid-solid silver interfaces. Linear regression fitting between the reciprocals of surface coverage and those of solution concentration from reductive desorption was observed, and meaningful progress of spectroelectrochem. mechanisms was made for surface chem.

Materials Chemistry and Physics published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C8H10BNO3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ruan, Mengjiao published the artcileCytosolic glucose-6-phosphate dehydrogenases play a pivotal role in Arabidopsis seed development, Related Products of catalysis-chemistry, the publication is Plant Physiology and Biochemistry (Issy-les-Moulineaux, France) (2022), 207-219, database is CAplus and MEDLINE.

Embryo development is essential for seed yield and post-germination growth. Glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme in oxidative pentose phosphate pathway (OPPP), is widely involved in plant development and stress tolerance by providing NADP (NADPH). In this study, the double mutant (g6pd5/6), overexpression line (G6PD5/6^OE) and complementation line (g6pd5/6^Comp) of cytosolic glucose-6-phosphate dehydrogenases (Cyt-G6PD) were used to investigate Cyt-G6PD roles in embryo development of Arabidopsis. The results showed that the germination rate of g6pd5/6 seeds was delayed in comparison with that of Col-0; moreover, 11.5% of g6pd5/6 seeds did not germinate. The dysfunction of Cyt-G6PD resulted in decreased fresh weight and primary root length of g6pd5/6 seedlings. The height and silique length of g6pd5/6 plants were also decreased. Moreover, the abortion rate of siliques and seeds of g6pd5/6 plants were increased compared with those of Col-0, G6PD5/6^OE and g6pd5/6^Comp lines. However, the dysfunction of Cyt-G6PD did not affect pollen activity; but in g6pd5/6, the embryo development was partially delayed or inhibited. The contents of fatty acids and storage proteins, two main storage materials in Arabidopsis seeds, were decreased in g6pd5/6 seeds. Exogenous application of fatty acids (C18:2; C18:3) alleviated the delayed germination of g6pd5/6 seeds. RT-qPCR results further demonstrated that the early embryo development genes were down-regulated in g6pd5/6. Taken together, Cyt-G6PD plays a pivotal role in plant seed development by regulating the transcriptions of early embryo development genes and the accumulation of storage materials (especially fatty acids).

Plant Physiology and Biochemistry (Issy-les-Moulineaux, France) published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Yulei published the artcileChemical synthesis of a full-Length G-protein-coupled receptor ¦Â₂-adrenergic receptor with defined modification patterns at the C-terminus, Category: catalysis-chemistry, the publication is Journal of the American Chemical Society (2021), 143(42), 17566-17576, database is CAplus and MEDLINE.

The ¦Â₂-adrenergic receptor (¦Â₂AR) is a G-protein-coupled receptor (GPCR) that responds to the hormone adrenaline and is an important drug target in the context of respiratory diseases, including asthma. ¦Â₂AR Function can be regulated by post-translational modifications such as phosphorylation and ubiquitination at the C-terminus, but access to the full-length ¦Â₂AR with well-defined and homogeneous modification patterns critical for biochem. and biophys. studies remains challenging. Here, we report a practical synthesis of differentially modified, full-length ¦Â₂AR based on a combined native chem. ligation (NCL) and sortase ligation strategy. An array of homogeneous samples of full-length ¦Â₂ARs with distinct modification patterns, including a full-length ¦Â₂AR bearing both monoubiquitination and octaphosphorylation modifications, were successfully prepared for the first time. Using these homogeneously modified full-length ¦Â₂AR receptors, we found that different phosphorylation patterns mediate different interactions with ¦Â-arrestin1 as reflected in different agonist binding affinities. Our experiments also indicated that ubiquitination can further modulate interactions between ¦Â₂AR and ¦Â-arrestin1. Access to full-length ¦Â₂AR with well-defined and homogeneous modification patterns at the C-terminus opens a door to further in-depth mechanistic studies into the structure and dynamics of ¦Â₂AR complexes with downstream transducer proteins, including G proteins, arrestins, and GPCR kinases.

Journal of the American Chemical Society published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liang, Pei published the artcileEffects of dietary omega-3 fatty acids on orthotopic prostate cancer progression, tumor associated macrophages, angiogenesis and T-cell activation-dependence on GPR120, Application of Docosahexaenoic Acid, the publication is Prostate Cancer and Prostatic Diseases (2022), 25(3), 539-546, database is CAplus and MEDLINE.

Abstract: Background: The antiprostate cancer effects of dietary ¦Ø-3 fatty acids (FAs) were previously found to be dependent on host G-protein coupled receptor 120 (GPR120). Using an orthotopic tumor model and an ex-vivo model of bone marrow derived M2-like macrophages, we sought to determine if ¦Ø-3 FAs inhibit angiogenesis and activate T-cells, and if these effects are dependent on GPR120. Methods: Gausia luciferase labeled MycCaP prostate cancer cells (MycCaP-Gluc) were injected into the anterior prostate lobe of FVB mice. After established tumors were confirmed by blood luminescence, mice were fed an ¦Ø-3 or ¦Ø-6 diet. Five weeks after tumor injection, tumor weight, immune cell infiltration and markers of angiogenesis were determined An ex-vivo co-culture model of bone marrow derived M2-like macrophages from wild-type or GPR120 knockout mice with MycCap prostate cancer cells was used to determine if docosahexanoic acid (DHA, ¦Ø-3 FA) inhibition of angiogenesis and T-cell activation is dependent on macrophage GPR120. Results: Feeding an ¦Ø-3 diet significantly reduced orthotopic MycCaP-Gluc tumor growth relative to an ¦Ø-6 diet. Tumors from the ¦Ø-3 group had decreased M2-like macrophage infiltration and decreased expression of angiogenesis factors. DHA significantly inhibited M2 macrophage-induced endothelial tube formation and reversed M2 macrophage-induced T-cell suppression, and these DHA effects were mediated, in part, by M2 macrophage GPR120. Conclusion: Omega-3 FAs delayed orthotopic tumor growth, inhibited M2-like macrophage tumor infiltration, and inhibited M2-like macrophage-induced angiogenesis and T-cell suppression. Given the central role of M2-like macrophages in prostate cancer progression, GPR120-dependent ¦Ø-3 FA inhibition of M2-like macrophages may play an important role in prostate cancer therapeutics.

Prostate Cancer and Prostatic Diseases published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Application of Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Guo, Yanxia published the artcileEffect of Hydrogen-Consuming Compounds on In Vitro Ruminal Fermentation, Fatty Acids Profile, and Microbial Community in Water Buffalo, Quality Control of 6217-54-5, the publication is Current Microbiology (2022), 79(8), 220, database is CAplus and MEDLINE.

The present study aimed to investigate the effect of hydrogen-consuming compounds on ruminal methane (CH4) production, in vitro fermentation parameters, fatty acids profile, and microbial community in water buffalo. Different sodium nitrate to disodium fumarate ratios [2:1 (F), 1:1 (S), 1:2 (T)] were studied in vitro by batch culture technique in the presence of linoleic acid. Results revealed that the dominant bacterial communities were not affected with sodium nitrate and disodium fumarate, whereas CH4 production and Verrucomicrobia, Succiniclasticum, norank_f__Muribaculaceae, and Prevotellaceae_UCG-003 were reduced (P < 0.05). However, ruminal pH, unsaturated fatty acids/saturated fatty acids (UFA/SFA) and Campilobacterota, Selenomonas, Succinivibrio, Oribacterium, Christensenellaceae_R-7_group, Campylobacter, Shuttleworthia, Schwartzia, and Prevotellaceae_YAB2003_group were increased (P < 0.05). Total volatile fatty acids (TVFA) and Spirochaetae, Fibrobacterota, Verrucomicrobia, Fibrobacter, Treponema, and Prevotellaceae were decreased in F (P < 0.05), but cis-9, trans-11CLA, acetate/propionate and Proteobacteria, Campilobacterota, Selenomonas, Succinivibrio, and Campylobacter were increased in F (P < 0.05). The highly selected bacterial genera in F were Campylobacter and Succinivibrio. The disodium fumarate, enhanced (P < 0.05) the TVFA, propionate, total bacteria, Butyrivibrio proteoclasticus, and Atypical butyrivibrio. The concentrations of C18:3n3, C20:3n6, C21:0, C22:2n6, and C22:1n9, as well as the populations of total fungi, protozoa, methanogens, Butyrivibrio hungatei in T were higher (P < 0.05). The highly selected bacterial genera in T were Fibrobacter and Treponema. Conclusively, the addition of sodium nitrate and disodium fumarate can reduce the CH4 production and optimize ruminal fatty acid composition Furthermore, disodium fumarate can alleviate the adverse effect of sodium nitrate on the rumen fermentation

Current Microbiology published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Quality Control of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Ziwei published the artcileEstimating the deposition of polycyclic aromatic hydrocarbons in human airways: The role of particle size, Category: catalysis-chemistry, the publication is Atmospheric Pollution Research (2022), 13(7), 101461, database is CAplus.

Most previous studies used atm. concentrations of polycyclic aromatic hydrocarbons (PAHs) to estimate the risk of exposure via inhalation, but neglected the disparities in the effects of particle size. In this study, an extensive literature search retrieved data from 35 cities on atm. PAHs and particle size distributions, and a multiple-path particle dosimetry model was used to simulate the PAH deposition in human airways. The results revealed that the median concentration of total PAHs was 38 (range, 0.6-2074.2) ng/m³, while the median concentration of benzo(a)pyrene equivalent (B[a]Peq) was 11 ng/m³. Together with exposure to congener-specific PAHs, the median deposited concentrations of total PAHs or B[a]Peq were the highest in particulate matter (PM) with diameters of 1-2.5 ¦Ìm, followed by > 1 ¦Ìm and coarse PM, which can be explained by the general increase in proportions of high mol. weight PAHs with decreasing PM size. While the deposited PAHs were dominated by 3-5 rings PAHs, the deposited B[a]Peq was concentrated in 5-ring. Moreover, although differences in the contributions of the ring number between deposited and ambient PAHs were negligible, the contributions of fine PM were 11.9% and 9.5% greater for deposited PAHs and B[a]Peq, resp. These results indicate that the risk of exposure to PAHs attached to fine PM is underestimated previously.

Atmospheric Pollution Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C6H12Br2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Marling, J. B. published the artcileLasing characteristics of seventeen visible-wavelength dyes using a coaxial-flashlamp-pumped laser, Product Details of C18H15N3O3, the publication is Applied Optics (1974), 13(10), 2317-20, database is CAplus and MEDLINE.

The performance and tuning characteristic of organic dye lasers were measured using com. available coaxial flashlamps as the pumping source. Tuning by a diffraction grating permitted continuous coverage of the 4200-7500-? region at up to 0.6% tuned output energy efficiency. Preliminary results with a 600-J Marx-Bank coaxial laser at 4500 ? show 1% efficiency and single-pass unsaturated gain >20 at 4500 ?.

Applied Optics published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Product Details of C18H15N3O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Cherian, Gita published the artcileEvaluation of two types of ingredients from marine fish rest raw materials in broiler diets: effects on live performance and meat lipid composition, Application In Synthesis of 6217-54-5, the publication is Journal of Applied Poultry Research (2022), 31(3), 100261, database is CAplus.

The current study investigated the effect of incorporating two ingredients derived from different types of marine fish rest raw materials in the diet of broiler chickens on live performance, carcass yield, muscle fatty acid (FA) composition, lipid peroxidation products, and blood metabolites. A total of ninety (n = 90), one-day-old Cobb chicks were fed a corn-soybean meal-based diet with no marine rest raw material (Control), 5% deboned Pacific hake meal (Diet 1), or 5% Pacific surimi washwater meal (Diet 2) for 42 d (30 birds per treatment kept in 6 replicate pens with 5 chicks per pen). For bird performance (feed consumption, weight gain), each replicate pen was considered as the exptl. unit. For determining yield, blood metabolites, and lipid anal., one bird collected from each replicate is considered as the exptl. unit. Bodyweight gain and feed:gain were determined at the starter (1-10), grower (11-21), and finisher (22-42) phases. For all response variables, the effects of Control vs. Diet 1 and Diet 2 were compared sep. using anal. of variance. P values were considered significant at ¡Ü0.05. No difference was observed in the body weight gain and feed:gain at day 10 (P > 0.05). At day 21, Diet 1 and Diet 2 birds were higher in body weight than Control (P < 0.05). At day 42, Diet 1 birds were highest in body weight (3,018 g) when compared to Control (2,728 g) (P < 0.05) and was not different from Diet 2 (2,912 g) (P > 0.05). Overall, feed:gain was lowest in Diet 2 (1.52) (P < 0.05) and was not different from Diet 1. A 2 to 5-fold increase in n-3 FA was observed in the breast and thigh muscle of Diet 1 and Diet 2 compared to Control (P < 0.05). Docosahexaenoic acid (DHA, 22:6 n-3) was the major long chain FA in the breast and thigh muscle and addition of marine rest raw material led to >10-fold increase in the breast and thigh muscle DHA in Diet 1 and Diet 2 when compared to Control (P < 0.05). The total lipid content of thigh muscle was lower in Diet 1 and Diet 2 compared to Control (P < 0.05). No difference was observed in the total lipid content of breast muscle (P > 0.05). The relative organ weight and yield of breast and thigh muscles were not different among the three treatments (P > 0.05). No difference was observed in moisture and cholesterol content in breast and thigh muscles (P > 0.05). Blood cholesterol was lower in Diet 1 than Control (P < 0.05). Lipid peroxidation products measured as thiobarbituric acid reactive substances (TBARS) were lower in the breast muscle of Diet 1 and Diet 2 compared to Control (P < 0.05). However, no effect of diet on thigh muscle TBARS was observed (P > 0.05). As consumer demands for n-3 FA-rich poultry products are on the rise, products derived from marine rest raw materials may serve as feed supplement that could be used in broiler chicken diets for enriching edible tissues with n-3 FA while increasing bird live performance and promoting ecol. poultry production

Journal of Applied Poultry Research published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Application In Synthesis of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Brugarolas, P. published the artcileSynthesis of meta-substituted [¹⁸F]3-fluoro-4-aminopyridine via direct radiofluorination of pyridine N-oxides, Recommanded Product: Tetrabutylammonium hydrogencarbonate, the publication is Chemical Communications (Cambridge, United Kingdom) (2016), 52(44), 7150-7152, database is CAplus and MEDLINE.

A methodol. for the preparation of 3-fluoro-4-aminopyridine was developed via two-step procedure involving fluorination of 3-bromo-4-nitropyridine N-oxide to yield 3-fluoro-4-nitropyridine N-oxide as an intermediate in first step and its reduction via catalytic hydrogenation in second step. Furthermore, this approach was successfully applied for the preparation of [¹⁸F]3-fluoro-4-aminopyridine. The use of pyridine N-oxides for the preparation of fluoropyridines was unprecedented in chem. literature and had potential to offer a new way for the synthesis of these important structures in pharmaceuticals and radiopharmaceuticals.

Chemical Communications (Cambridge, United Kingdom) published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Recommanded Product: Tetrabutylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Alauddin, Mian M. published the artcileSynthesis of [¹⁸F]-labeled adenosine analogs as potential PET imaging agents, Formula: C17H37NO3, the publication is Journal of Labelled Compounds & Radiopharmaceuticals (2003), 46(9), 805-814, database is CAplus.

The syntheses of adenosine analogs, 2′-deoxy-2′-[¹⁸F]fluoro-9-¦Â-D-arabinofuranosyladenine ([¹⁸F]-FAA) and 3′-deoxy-3′-[¹⁸F]fluoro-9-¦Â-D-xylofuranosyladenine ([¹⁸F]-FXA) from adenosine via reaction with tetrabutylammonium[¹⁸F]fluoride, are reported. Crude preparations were purified by HPLC to obtain the desired pure products. The radiochem. yields were 10-18% decay corrected (d.c.) for [¹⁸F]-FAA and 30-40% (d.c.) for [¹⁸F]-FXA in 4 and 3 runs, resp. Radiochem. purity was >99% and specific activity was > 74 GBq/¦Ìmol at the end of synthesis (EOS). The synthesis time was 90-95 min from the end of bombardment (EOB).

Journal of Labelled Compounds & Radiopharmaceuticals published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Formula: C17H37NO3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia