Month: December 2022

Mikes, Monica published the artcileTranslating PUFA omega 6:3 ratios from wild to captive hibernators (Urocitellus parryii) enhances sex-dependent mass-gain without increasing physiological stress indicators, Name: Docosahexaenoic Acid, the publication is Journal of Comparative Physiology, B: Biochemical, Systems, and Environmental Physiology (2022), 192(3-4), 529-540, database is CAplus and MEDLINE.

Omega 3 polyunsaturated fatty acids (PUFAs) are well-documented for their influence on health and weight loss. Recent studies indicate omega 3 PUFAs may exert a neg. impact on cellular stress and physiol. in some hibernators. We asked if physiol. stress indicators, lipid peroxidation and mass gain in Arctic Ground Squirrels (AGS) were neg. influenced by naturally occurring dietary omega 3 PUFA levels compared to omega 3 PUFA levels found in common laboratory diets. We found plasma fatty acid profiles of free-ranging AGS to be high in omega 3 PUFAs with balanced omega 6:3 ratios, while standard laboratory diets and plasma of captive AGS are high in omega 6 and low in omega 3 PUFAs with higher omega 6:3 ratios. Subsequently, we designed a diet to mimick free-range AGS omega 6:3 ratios in captive AGS. Groups of wild-caught juvenile AGS were either fed: (1) Mazuri Rodent Chow (Standard Rodent chow, 4.95 omega 6:3 ratio), or (2) balanced omega 6:3 chow (Balanced Diet, 1.38 omega 6:3). AGS fed the Balanced Diet had plasma omega 6:3 ratios that mimicked plasma profiles of wild AGS. Balanced Diet increased female body mass before hibernation, but did not influence levels of cortisol in plasma or levels of the lipid peroxidation product 4-HNE in brown adipose tissue. Overall, as the mass gain is critical during pre-hibernation for obligate hibernators, the results show that mimicking a fatty acid profile of wild AGS facilitates sex-dependent mass accumulation without increasing stress indicators.

Journal of Comparative Physiology, B: Biochemical, Systems, and Environmental Physiology published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Name: Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Korsmeyer, Julie M. published the artcileInfrared Spectroscopy and Photochemistry of Anthracoronene in Cosmic Water Ice, Application In Synthesis of 191-07-1, the publication is ACS Earth and Space Chemistry (2022), 6(1), 165-180, database is CAplus and MEDLINE.

We present a laboratory study of the polycyclic aromatic hydrocarbon (PAH) anthracoronene (AntCor, C₃₆H₁₈) in simulated interstellar ices in order to determine its possible contribution to the broad IR absorption bands in the 5-8¦Ìm wavelength interval. The Fourier transform IR (FTIR) spectrum of AntCor, codeposited with water ice, was collected. The FTIR spectrum of the sample irradiated with UV photons was also collected. Unirradiated and UV-irradiated AntCor embedded in water ice have not been studied before; therefore, the mol.’s band positions and intensities were compared to published data on AntCor in an argon matrix and theor. calculations (DFT), as well as the published results of its parent mols., coronene and anthracene, in water ice. The exptl. band strengths for unirradiated AntCor exhibit variability as a function of PAH:H₂O concentration, with two distinct groupings of band intensities. AntCor clustering occurs for all concentrations and has a significant effect on PAH degradation rates and photoproduct variability. Near-IR spectra of irradiated AntCor samples show that AntCor⁺ production increases as the concentration of AntCor in water ice decreases. Photoproduct bands are assigned to AntCor⁺, cationic alcs., protonated AntCor, and ketones. We report the rate constants of the photoproduct production for the 1:1280 AntCor:H₂O concentration CO₂ production from AntCor is much less than what was previously reported for Ant and Cor and exhibits two distinct regimes as a function of AntCor:H₂O concentration The contribution of AntCor photoproducts to astronomical spectra can be estimated by comparison with the observed intensities in the 7.4-8.0¦Ìm range.

ACS Earth and Space Chemistry published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Application In Synthesis of 191-07-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Khalili, Dariush published the artcileImpregnated copper ferrite on mesoporous graphitic carbon nitride: An efficient and reusable catalyst for promoting ligand-free click synthesis of diverse 1,2,3-triazoles and tetrazoles, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Applied Organometallic Chemistry (2019), 33(11), e5219, database is CAplus.

Synthesis of magnetic CuFe₂O₄/g-C₃N₄ hybrids via a facile method and their catalytic performances were evaluated via click chem. was reported. The structural and morphol. characterization of CuFe₂O₄, g-C₃N₄, CuFe₂O₄/g-C₃N₄ were carried out by different techniques such as X-ray diffraction, high-resolution transmission electron microscopy, field emission SEM, Fourier IR spectroscopy, vibrating sample magnetometry, thermogravimetric anal. and N₂ adsorption-desorption anal. (Brunauer-Emmett-Teller surface area). The utilization of magnetic CuFe₂O₄/g-C₃N₄ enabled superior performance in the one-pot azide-alkyne cycloaddition reaction in water using alkyl halides and epoxides as azide precursors without the need of any addnl. agents to afford triazoles I [R = cyclohexyl, allyl, Bn, etc.; Ar = Ph, 2-methoxynaphthalenyl] and II [Ar¹ = Ph, 2-methoxynaphthalenyl; R¹ = H, Ph, 4-ClC₆H₄; R² = H, Et, CH₂OPh, etc.]. Also 5-substituted 1H-tetrazoles III [Ar² = Ph, 4-MeC₆H₄, 2-ClC₆H₄, etc.] were prepared via [3 + 2] cycloaddition of sodium azide and aryl nitriles by using magnetic CuFe₂O₄/g-C₃N₄ nanoparticles. In addition, the catalytic system highly fulfilled the demands of “green click chem.” with its convenient conditions, especially easy access to a variety of significant products in low catalyst loading and simple work-up and isolation procedure.

Applied Organometallic Chemistry published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Navarrete, Andres published the artcileSynthesis and nematocidal activities of N-(2-methylpropyl)-3-(X-phenyl)-2E-propenamides, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Proceedings of the Western Pharmacology Society (2002), 114-117, database is CAplus and MEDLINE.

Various N-(2-methylpropyl)-3-(X-phenyl)-2E-propenamides were synthesized and evaluated for their nematocidal activities. N-(2-methylpropyl)-3-(X-phenyl)-2E propenamides, in which x was equal to -Cl, -F or -NO₂ at position 3 or di-OCH₃ at position 3,4 in the aromatic ring, showed nematocidal activity in vitro against Ascaris suum inducing morphol. changes in the cephalic region.

Proceedings of the Western Pharmacology Society published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Posada, Laura published the artcileCyclopeptides Natural Products as Herbicides and Inhibitors of Cyanobacteria: Synthesis of Versicotides E and F, Application of Fmoc-Pro-OH, the publication is ChemistrySelect (2022), 7(27), e202201956, database is CAplus.

The first total synthesis of cyclopeptides versicotide E and F, natural products produced by marine fungus Aspergillus versicolor LZD-14-1, was achieved in good yield by solid phase peptide synthesis (SPPS) of their linear precursors and solution phase cyclization. All the versicotides A-F were evaluated as herbicides and inhibitors of cyanobacterial growth. Versicotides A, B, D, E and F showed a significant inhibition of Rye grass seed¡äs radicle growth at a concentration of 67 ¦Ìg/mL. Versicotides A, B and D also inhibited seed germination and leaf development. On the other hand, Versicotides D and F caused a relevant reduction on Microcystis aeruginosa population when cultures on exponential growth were incubated with 40 ¦Ìg/mL solutions of these compounds Evaluation of the concentration of microcystins after these treatments showed that versicotide D inhibited the production of microcystins in a comparable extent to the pos. control, colistine. These results indicate versicotides, with versicotides D and F as top hits, could be considered as lead candidates in the development of bioherbicides able to mitigate the environmental impact that the evolution of agriculture has had on water quality.

ChemistrySelect published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Application of Fmoc-Pro-OH.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bala Subramanian, M. published the artcileFormation of waveguides in crystalline organic N-benzyl-2-methyl-4-nitroaniline thin films using femtosecond laser ablation process, Quality Control of 201157-13-3, the publication is Materials Letters (2021), 130220, database is CAplus.

This paper reports the feasibility of femtosecond laser etching of microstructures directly onto crystalline N-benzyl-2-methyl-4-nitroaniline (BNA) films grown on glass to realize single crystal BNA waveguides. The threshold fluence has been estimated and fluence range of 318.5-1274 mJ/cm² at 800 nm is used for ablation. Holes with diameter ranging from 13 to 26¦Ìm and waveguide patterns with width of 100¦Ìm are demonstrated. Grooves with laser transit gap <20¦Ìm is used to form smaller waveguides. Input faces of the waveguides have been simultaneously irradiated with red laser of 630 nm. The optical image of transmission confirms the wave-guiding. This study shows the feasibility of laser-etching waveguides on crystalline BNA films.

Materials Letters published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C14H14N2O2, Quality Control of 201157-13-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Schrittwieser, Joerg H. published the artcileBiocatalytic Enantioselective Oxidative C-C Coupling by Aerobic C-H Activation, Application In Synthesis of 1860-58-8, the publication is Angewandte Chemie, International Edition (2011), 50(5), 1068-1071, S1068/1-S1068/144, database is CAplus and MEDLINE.

The berberine bridge enzyme (BBE) was employed for the first preparative oxidative biocatalytic C-C coupling that leads to a new intramol. bond. This unique transformation requires O₂ as sole stoichiometric oxidant and gives access to novel optically pure (S)-berbine and (R)-1-benzyl-1,2,3,4-tetrahydroisoquinoline alkaloid derivatives by kinetic resolution

Angewandte Chemie, International Edition published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Application In Synthesis of 1860-58-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Schrittwieser, Joerg H. published the artcileBiocatalytic Organic Synthesis of Optically Pure (S)-Scoulerine and Berbine and Benzylisoquinoline Alkaloids, COA of Formula: C15H14O3, the publication is Journal of Organic Chemistry (2011), 76(16), 6703-6714, database is CAplus and MEDLINE.

A chemoenzymic approach for the asym. total synthesis of the title compounds was described that employs an enantioselective oxidative C-C bond formation catalyzed by berberine bridge enzyme (BBE) in the asym. key step. This unique reaction yielded enantiomerically pure (R)-benzylisoquinoline derivatives and (S)-berbines such as the natural product (S)-scoulerine (I), a sedative and muscle relaxing agent. The racemic substrates required for the biotransformation were prepared in 4-8 linear steps using either a Bischler-Napieralski cyclization or a C1-C¦Á alkylation approach. The chemoenzymic synthesis was applied to the preparation of fourteen enantiomerically pure alkaloids, including the natural products (S)-scoulerine and (R)-reticuline (II), and gave overall yields of up to 20% over 5-9 linear steps.

Journal of Organic Chemistry published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, COA of Formula: C15H14O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huang, Dejian published the artcileCleavage of F-C(sp²) bonds by MHR(CO)(P^tBu₂Me)₂ (M = Os and Ru; R = H, CH₃ or Aryl): Product dependence on M and R, Product Details of C9H9F5Si, the publication is Polyhedron (2006), 25(2), 459-468, database is CAplus.

Both MH(Ph)(CO)L₂ (L = P^tBu₂Me; M = Ru and Os) react with vinyl fluoride to form M-F bonds; however, Ru eliminates benzene, while Os eliminates ethylene. In contrast, Ru(H)₂(CO)L₂ and Os(H)₂(CO)(1-butene)L₂ both react with vinyl fluoride to give ethylene and MHF(CO)L₂. Ethylene production from both dihydrides is attributed to ¦Â-F migration to M from an MCH₂CH₂F transient, while the unique behavior of RuH(Ph)(CO)L₂ (giving the C-F oxidative addition product Ru(¦Ç¹-vinyl)F(CO)L₂) is attributed to the difficulty of achieving Ru^IV, and the ability of the strongly ¦Ð-acidic vinyl fluoride to rapidly trigger reductive elimination of benzene. The products of reaction of RuH(Ar)(CO)L₂ with vinyl fluoride are redirected more towards ethylene formation when Ar carries fluorine substituents. The reaction products of OsH(R)(CO)L₂ with vinyl fluoride revert to R-H elimination when R is Me. Finally, the more ¦Ð-acidic H₂C:CF₂ triggers very rapid CH₄ elimination from OsH(CH₃)(CO)L₂; cleavage of the second C-F bond yields the vinylidene OsF₂(CCH₂)(CO)L₂. All selectivity is rationalized via the fate of the adduct MH(R)(C₂H_4-nF_n)(CO)L₂.

Polyhedron published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Product Details of C9H9F5Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Qiu, Zi-bin published the artcileMgBr₂¡¤OEt₂promoted direct Aldol reactions of S-aryl 2-fluoroethanethioate, Related Products of catalysis-chemistry, the publication is Journal of Fluorine Chemistry (2019), 109368, database is CAplus.

MgBr₂¡¤OEt₂-promoted direct aldol reactions of S-aryl 2-fluoroethanethioates with aromatic aldehydes to give the corresponding ¦Á-fluoro-¦Â-hydroxythioesters I [R = Ph, 4-ClC₆H₄, 3,4-Me₂C₆H₃, etc.; Ar = 4-MeC₆H₄, 2,6-Me₂C₆H₃, 2,4,6-iPr₃C₆H₂] was reported. This method had the advantages of use of com. available reagents, mild reaction conditions and operational simplicity.

Journal of Fluorine Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia