Month: December 2022

Drasar, Pavel published the artcileSteroids. Part CCCXLVII. Synthesis and in vitro antimetabolic evaluation of some steroidal thiazoles, Synthetic Route of 6972-05-0, the publication is Collection of Czechoslovak Chemical Communications (1989), 54(12), 3339-47, database is CAplus.

Steroidal thiazoles I (R = NH₂, NHMe, NHPh, NMe₂, Ph, Me, CH₂CO₂Me) have been synthesized. The starting bromo ketone II (R¹ = Br) was prepared by bromination of pregnen-20-ones II (R¹ = H) with copper (II) bromide, and was used for synthesis of the thiazole derivatives employing the Hantzsch reaction. Preliminary biol. evaluation of thiazoles I and III against the P388 lymphocytic leukemia cell showed growth inhibition values of ED₅₀ 2.9 and 7 ¦Ìg/mL for thiazoles III and I (R = NH₂), resp. Other I were less active.

Collection of Czechoslovak Chemical Communications published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Synthetic Route of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hosseini, Samanesadat published the artcileNickel Supported MCM-Functionalized 1,2,3-Triazol-4-ylmethanamine: An Efficient Nano-particle-Heterogeneous Catalyst Activate for Suzuki Reaction, HPLC of Formula: 613-33-2, the publication is Catalysis Letters (2022), 152(7), 2186-2199, database is CAplus.

A novel, potent, efficient, and reusable heterogeneous nanocatalyst was prepared and grafted nickel into MCM-functionalized 1,2,3-Triazol-4-ylmethanamine (MCM-TA@Ni). The catalyst was characterized by various physico-chem. anal. such as Fourier transform IR spectroscopy, SEM, transmission electron microscopy, X-ray diffraction, thermo gravimetric anal., Brunauer-Emmett-Teller (BET), at. absorption spectroscopy, and energy dispersive X ray spectroscopy techniques. The catalytic activity of this recoverable nanocatalyst was studied for the carbon-carbon bond formation (Suzuki-Miyaura).

Catalysis Letters published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, HPLC of Formula: 613-33-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Keshavarz, Mohammad Hossein published the artcileSimple Method for Prediction of the Standard Gibbs Free Energy of Formation of Energetic Compounds, Application In Synthesis of 1821-27-8, the publication is Propellants, Explosives, Pyrotechnics (2014), 39(6), 815-818, database is CAplus.

A reliable simple method for prediction of the standard Gibbs energy of formation (¦¤_fG^¦È) of energetic compounds containing nitroarom., acyclic, and cyclic nitramine, nitrate ester, and nitroaliph. compounds is introduced herein. The method is based on the contribution of elemental composition (¦¤_fG_elem^¦È) and the correcting function for the presence of additive and non-additive mol. fragments (¦¤_fG_corr^¦È). In presence of some mol. moieties, ¦¤_fG_corr^¦È may increase or decrease the value of ¦¤_fG_elem^¦È, depending on the intermol. interactions. The exptl. root-mean-square error (RMSE) of the novel correlation (22.7 kJ mol^-1) is quite good. For some energetic compounds, where the computed values of two complex models of the quant. structure-property relationship (QSPR) theory were available, the exptl. RMSE developed by the new method is smaller than the values obtained by QSPR method.

Propellants, Explosives, Pyrotechnics published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Application In Synthesis of 1821-27-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Poyet, J. M. published the artcileAnalysis of stabilizers, plasticizers and impurities in explosives by liquid chromatography, SDS of cas: 1821-27-8, the publication is Symposium on Chemical Problems Connected with the Stability of Explosives, [Proceedings] (1977), 109-20, database is CAplus.

High-pressure liquid chromatog. (HPLC) has been used to determine nitroso and nitro derivatives of diphenylamine [122-39-4] and 2-nitrodiphenylamine [119-75-5] stabilizers in nitrocellulose [9004-70-0] and poly(vinyl nitrate) [26355-31-7] explosive powders. In the determination of diphenylamine derivatives, Microporasil was used as column packing and cyclohexane-1,2-dichloroethqne mixture as eluant. 2-Nitrodiphenylamine derivatives were estimated by inverse phase chromatog. on a Microbondapak C-18 1/4 column with MeOH-H2O (67.5:32.5) as eluant and (PhO)3PO as internal standard Trace amounts (0.01%) of RDX [121-82-4] in HMX [2691-41-0] also could be estimated on the Microporasil column with cyclohexane-dioxane-MeCN (63:34:3) as eluant.

Symposium on Chemical Problems Connected with the Stability of Explosives, [Proceedings] published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, SDS of cas: 1821-27-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Blondiaux, Enguerrand published the artcileCarbon dioxide reduction to methylamines under metal-free conditions, COA of Formula: C14H23N, the publication is Angewandte Chemie, International Edition (2014), 53(45), 12186-12190, database is CAplus and MEDLINE.

The metal-free catalysts are reported for the methylation of amines with carbon dioxide. Proazaphosphatrane superbases prove to be highly active catalysts in the reductive functionalization of CO₂, in the presence of hydroboranes. The new methodol. enables the methylation of N-H bonds in a wide variety of amines, including secondary amines, with increased chemoselectivity.

Angewandte Chemie, International Edition published new progress about 2909-77-5. 2909-77-5 belongs to catalysis-chemistry, auxiliary class Amine,Benzene, name is 2,6-Diisopropyl-N,N-dimethylaniline, and the molecular formula is C14H23N, COA of Formula: C14H23N.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rolland, Herve published the artcileUse of tin derivatives for selective allylation and methylation of halophosphorus compounds, Application of Allyldiphenylphosphine oxide, the publication is Tetrahedron Letters (1992), 33(52), 8095-8, database is CAplus.

Palladium(0) catalyzed gem-dimethylation of hexachlorocyclotriphosphazene with tetramethylstannane is described as well as the high yield monoallylation of halophosphorus or -boron compounds by allyltrialkylstannanes under photolytic conditions.

Tetrahedron Letters published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Application of Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Khanapure, Sharanabasappa published the artcileSustainable Synthesis of Biaryls Using Silica Supported Ferrocene Appended N-Heterocyclic Carbene-Palladium Complex, Product Details of C14H14, the publication is Catalysis Letters (2021), 151(8), 2237-2249, database is CAplus.

Abstract: A novel silica supported ferrocene appended N-heterocyclic carbene-palladium complex (SilFemBenzNHC@Pd) has been prepared and characterized by using fourier transform IR (FT-IR), fourier transform Raman (FT-Raman), XPS, SEM (SEM), thermogravimetric anal. (TGA) and energy dispersive X-ray anal. (EDX). This novel complex served as a robust heterogeneous catalyst for the synthesis of biaryls via homocoupling of aryl boronic acids under base-free conditions in water. Recyclability experiments were executed successfully for six successive runs.

Catalysis Letters published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, Product Details of C14H14.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lu, Jun published the artcilePharmacokinetics, pharmacodynamics, and metabolism of triethylenetetramine in healthy human participants: an open-label trial, COA of Formula: C6H20Cl2N4, the publication is Journal of Clinical Pharmacology (2010), 50(6), 647-658, database is CAplus and MEDLINE.

The selective Cu^II-chelator, triethylenetetramine (TETA), is undergoing clin. trials for the treatment of heart failure in patients with diabetes. Recently, the authors showed that 2 acetylated metabolites, N₁-acetyltriethylenetetramine (MAT) and N₁,N₁₀-diacetyltriethylenetetramine (DAT), are formed in humans following oral TETA administration. Thus, it became necessary to determine whether the N-acetyltransferase (NAT) 2 phenotype has any effects on the pharmacol. properties and safety profile of TETA. Twelve fast and 12 slow NAT2-phenotype healthy participants were recruited. After oral drug administration, the authors collected plasma and urine samples, measured plasma concentrations of TETA and its 2 metabolites along with concomitant urinary copper concentrations, and performed safety tests. They present, for the first time, the complete 24-h pharmacokinetic profiles of TETA, MAT, and DAT in humans. There was no evidence for clear-cut differences in pharmacokinetic profiles between fast and slow acetylators. Pharmacodynamic anal. showed no significant differences in cupruresis between the 2 NAT2 phenotypes. Safety results were consistent with TETA being well tolerated, and no significant differences in safety profiles were observed between the 2 phenotypes. Based on these data, NAT2 phenotype does not affect TETA’s pharmacokinetic, pharmacodynamic, or safety profiles. TETA may be acetylated via an alternative mechanism, such as that catalyzed by spermidine/spermine N₁-acetyltransferase.

Journal of Clinical Pharmacology published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, COA of Formula: C6H20Cl2N4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rosen, Tomer published the artcileZinc Complexes of Sequential Tetradentate Monoanionic Ligands in the Isoselective Polymerization of rac-Lactide, Product Details of C16H20N2, the publication is Chemistry – A European Journal (2016), 22(33), 11533-11536, database is CAplus and MEDLINE.

Zinc complexes of {ONNN}-type sequential tetradentate monoanionic ligands reacted with diethylzinc to give the mononuclear ethylzinc complexes. The benzyloxy complexes were formed readily and were found to be highly active as well as living/immortal catalysts for ring-opening polymerization of rac-lactic acid with a clear isospecific inclination. Chiral gas chromatog. anal. revealed a mild preference for a given lactide enantiomer by the chiral catalysts.

Chemistry – A European Journal published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Product Details of C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

ChooChuay, Chomsri published the artcileEffects of Agricultural Waste Burning on PM_2.5-Bound Polycyclic Aromatic Hydrocarbons, Carbonaceous Compositions, and Water-Soluble Ionic Species in the Ambient Air of Chiang-Mai, Thailand, Product Details of C24H12, the publication is Polycyclic Aromatic Compounds (2022), 42(3), 749-770, database is CAplus.

PM_2.5 is a widely regarded major air pollutant due to its adverse health effect and intimate relationship with the climate system. This work characterized the chem. components (e.g., organic and elemental C [OC, EC], water soluble ionic species [WSIS], polycyclic aromatic hydrocarbons [PAH]) in PM_2.5 collected over Doi-Inthanon in Chiang-Mai, the highest mountain in Thailand. All samples (n = 50) were collected by MiniVolTM portable air samplers Mar. 2017-Mar. 2018. The average PM_2.5 concentration was 100 ¡À 48.6¦Ìg/m³. The OC:EC ratio was 6.8 ¡À 3.0; the decreasing order of WSIS concentrations was: SO₄^2- > Na⁺ > Ca²⁺ > NH₄⁺ > NO₃^– > K⁺ > Cl^– > NO₂^– > Mg²⁺ > F^–. Total concentrations of nineteen PAH were defined as the sum of Ace, Fl, Phe, Ant, Fluo, Pyr, B[a]A, Chry, B[b]F, B[k]F, B[a]F, B[e]P, B[a]P, Per, Ind, B[g,h,i]P, D[a,h]A, Cor, and D[a,e]P. The total PAH concentration 2.361 ¡À 2.154¦Ìg/m³. Principal component anal. (PCA) highlighted the importance of vehicle exhaust, biomass burning, diesel emissions, sea-salt aerosols, and fertilizer volatilization as the five dominant potential sources, accounting for 51.6, 16.2, 10.6, 5.20, and 3.70% of total variance, resp. The remaining 12.7% variance is associated with unidentified local and regional sources, e.g., incinerators, joss paper/incense burning, domestic cooking. PCA source estimation results underlined the importance of vehicle exhaust as the major PM_2.5 contributor in ambient air over Don-Inthanon, Chiang-Mai Province. It is crucial to emphasize the effect of agricultural waste burning, fossil fuel combustion, coal combustion, and forest fires on OC, EC, and WSIS concentration variations was not negligible.

Polycyclic Aromatic Compounds published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Product Details of C24H12.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia