Month: December 2022

Liu, Fangfei published the artcileTannic Acid: A green and efficient stabilizer of Au, Ag, Cu and Pd nanoparticles for the 4-Nitrophenol Reduction, Suzuki-Miyaura coupling reactions and click reactions in aqueous solution, Related Products of catalysis-chemistry, the publication is Journal of Colloid and Interface Science (2021), 281-291, database is CAplus and MEDLINE.

Due to the good elec., optical, magnetic, catalytic properties, transition metal nanoparticles (TMNPs) have been becoming more and more interesting in the fileds of environment, material, biomedicine, catalysis, and so on. Here, tannic acid (TA) is used as a green and efficient stabilizer to fabricate all kinds of TMNPs including AuNPs, AgNPs, CuNPs, and PdNPs. These TMNPs possess small sizes ranging from 1 nm to 6 nm, which is conducive to several catalytic reactions in aqueous solution, such as 4-nitrophenol (4-NP) reduction, CuAAC reactions and Suzuki-Miyaura coupling reactions. AuNPs and PdNPs are found to have distinctly higher catalytic activities than AgNPs and CuNPs in the 4-NP reduction process. Especially, PdNPs show the highest catalytic activities with TOF up to 7200 h^-1 in the 4-NP reduction Furthermore, PdNPs also exhibit satisfying catalytic performance in the Suzuki-Miyaura coupling process, and CuNPs are catalytically active in the copper-catalyzed azide alkyne cycloaddition (CuAAC) reactions. The applicability and generality of PdNPs and CuNPs are resp. confirmed via the reaction between different substrates in the Suzuki-Miyaura coupling reactions and the CuAAC reactions. This work present a simple, fast, green and efficient strategy to synthesize TMNPs for multiple catalysis.

Journal of Colloid and Interface Science published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Yajun published the artcileIdentification and structure-activity studies of 1,3-Dibenzyl-2-aryl imidazolidines as novel Hsp90 inhibitors, Product Details of C16H20N2, the publication is Molecules (2019), 24(11), 2105, database is CAplus and MEDLINE.

Hsp90 (Heat shock protein 90) is involved in various processes in cancer occurrence and development, and therefore represents a promising drug target for cancer therapy. In this work, a virtual screening strategy was employed, leading to the identification of a series of compounds bearing a scaffold of 1,3-dibenzyl-2-aryl imidazolidine as novel Hsp90 inhibitors. Compound 4a showed the highest binding affinity to Hsp90a (IC₅₀ = 12 nM) in fluorescence polarization (FP) competition assay and the strongest anti-proliferative activity against human breast adenocarcinoma cell line (MCF-7) and human lung epithelial cell line (A549) with IC₅₀ values of 21.58 M and 31.22 M, resp. Western blotting assays revealed that these novel Hsp90 inhibitors significantly down-regulated the expression level of Her2, a client protein of Hsp90, resulting in the cytotoxicity of these novel Hsp90 inhibitors. The mol. docking study showed that these novel Hsp90 inhibitors bound to the ATP (ATP) binding site at the N-terminus of Hsp90. Furthermore, structure-activity relationship studies indicated that the N-benzyl group is important for the anti-cancer activity of 1,3-dibenzyl-2-aryl imidazolidines.

Molecules published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Product Details of C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhao, Zijian published the artcileCopper-Catalyzed (Di)Arylmethylation of Phosphorylamides Under Oxidative Conditions, Synthetic Route of 457-68-1, the publication is European Journal of Organic Chemistry (2018), 2018(48), 6857-6866, database is CAplus.

A compatible and practical (di)arylmethylation of phosphorylamides was successfully accessed in the presence of copper iodide as the catalyst, azodiisobutyronitrile as the radical initiator, and di-tert-Bu peroxide as the oxidant. Both methylarenes and diaryl methanes were compatible under the oxidative conditions, enjoying broad functional groups tolerance (51 examples) and good efficiency (up to 90 % yields).

European Journal of Organic Chemistry published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C40H35N7O8, Synthetic Route of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Yong-Gang published the artcilePalladium/Copper-Catalyzed Oxidative Arylation of Terminal Alkenes with Aroyl Hydrazides, SDS of cas: 4141-48-4, the publication is Chemistry – A European Journal (2014), 20(10), 2765-2769, database is CAplus and MEDLINE.

An unprecedented oxidative arylation reaction of terminal alkenes with simple aroyl hydrazides has been developed under aerobic conditions for a stereoselective synthesis of 1,2-disubstituted alkenes. A range of aroyl hydrazides underwent palladium/copper-catalyzed oxidative Mizoroki-Heck reaction with terminal alkenes open to air in a 1:1 mixture of DMSO and acetonitrile to give structurally diverse 1,2-disubstituted alkenes in moderate to excellent yields with excellent regio- and E-selectivity. The reaction tolerated a wide variety of functional groups, such as alkoxy, hydroxy, amino, fluoro, chloro, bromo, cyano, nitro, ester, amide, imide, phosphine oxide, and sulfone groups, and, moreover, mol. oxygen and DMSO were demonstrated to serve as terminal oxidants. This study provides a useful method for the stereoselective synthesis of 1,2-disubstituted alkenes by a direct transformation of the vinylic carbon-hydrogen bonds (C-H bonds) in terminal alkenes.

Chemistry – A European Journal published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C8H14O4, SDS of cas: 4141-48-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Dongfang published the artcileMagnetic polymer nanocomposite-supported Pd: an efficient and reusable catalyst for the Heck and Suzuki reactions in water, Name: (E)-3-(3-Nitrophenyl)acrylic acid, the publication is New Journal of Chemistry (2015), 39(3), 2052-2059, database is CAplus.

A novel type of magnetically responsive polymer nanocomposite Fe₃O₄@poly(undecylenic acid-co-4-vinyl pyridine-co-sodium acrylate) (Fe₃O₄@PUVS) was synthesized by the free radical polymerization of 4-vinyl pyridine (4-VP) with sodium acrylate (SAA) and Fe₃O₄@undecylenic acid. Pd²⁺ was then immobilized on this magnetic nanocomposite to form the magnetic Fe₃O₄@PUVS-Pd catalyst. This catalyst exhibited excellent catalytic activity for the Heck and Suzuki coupling reactions in water, and could be simply separated by using a permanent magnet. The supported catalyst could be used consecutively for six runs without significant loss of catalytic activity.

New Journal of Chemistry published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C7H16ClNO2, Name: (E)-3-(3-Nitrophenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shen, Zhenpeng published the artcileIron-Promoted Decarboxylation of Arylacetic Acids for the Synthesis of Aromatic Nitriles with Sodium Nitrite as the Nitrogen Source, Quality Control of 104-03-0, the publication is Synlett (2020), 31(18), 1805-1808, database is CAplus.

A new and effective method was developed for the synthesis of aromatic nitriles ArCN (Ar = 4-chlorophenyl, naphthalen-1-yl, thiophen-2-yl, etc.) (I) from arylacetic acids ArCH₂C(O)OH (II) by using NaNO₂ as the nitrogen source and Fe(OTf)₃ as the promoter at 50¡ãC. A series of arylacetic acids II underwent this transformation to give the targeted products I in yields of 51-90%. Because of the mild conditions, the reaction is compatible with a broad range of functional groups, including ester, carboxy, hydroxy, acetamido, halo, nitro, cyano, methoxy, and even highly reactive formyl groups.

Synlett published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C18H21BO4, Quality Control of 104-03-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Peng, Xiangyu published the artcileDevelopment and utilization of a novel hydrogen bonding enhanced collector in the separation of apatite from quartz, COA of Formula: C14H31NO2, the publication is Minerals Engineering (2022), 107477, database is CAplus.

In the light of the adsorption difference of cationic collectors on quartz and apatite, an addnl. hydrogen bond functional group can be introduced into the traditional collector mol.-dodecylammonium acetate (DDA) to achieve high-efficient separation of minerals. In this study, a new surfactant-N-(2-hydroxy-1, 1-dimethylethyl) dodecylamine (HDMEA) was synthesized in our laboratory and acted as a new-type amine collector in the reverse flotation separation of apatite from quartz. The results of micro-flotation tests indicated that the separation performance of HDMEA was significantly better than that of DDA. When the concentration of HDMEA was 20 mg/L at pH 6.43, the apatite with 38.57% grade and 95.8% recovery could be achieved in mixed-flotation tests. The adsorption mechanism of DDA and HDMEA on quartz and apatite was comparably explored by the measurements of zeta potential, FTIR, contact angle, and AFM as well as the DFT calculations These results demonstrated that improving the hydrogen bonds adsorption on quartz (by -NH- and -OH groups) and increasing the steric-hindrance effect on apatite help to achieve efficient flotation separation of quartz and apatite.

Minerals Engineering published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, COA of Formula: C14H31NO2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bordwell, Frederick G. published the artcileEffects of sulfenyl, sulfinyl and sulfonyl groups on acidities and homolytic bond dissociation energies of adjacent C-H and N-H bonds, Recommanded Product: N-(tert-Butyl)-S-phenylthiohydroxylamine, the publication is Journal of Physical Organic Chemistry (1998), 11(6), 397-406, database is CAplus.

Acidities and bond dissociation energies (BDEs) of the N-H bond in two phenylsulfenylamides, PhSNHBz and PhSNH-t-Bu, and four phenylsulfenylanilides, 4-GC₆H₄NHSPh, where G=MeO, H, Br and CN, were measured in order to compare the effects of substituents on acidities and BDEs of N-H bonds with those of C-H bonds. The effects of PhS groups on acidities and BDEs in a series of C-H acids were found to be comparable to those on acidities and BDEs of PhS in a similar series of N-H acids. Comparisons were also made of the effects of changing the oxidation state of sulfur in the series PhS, PhSO and PhSO₂ on the acidities and BDEs of adjacent N-H and C-H bonds in weak acids. Hammett-type plots of pK_HA values for Ph benzyl sulfones (4-GC₆H₄CH₂SO₂Ph) and phenylsulfenylanilides (4-GC₆H₄NHSPh) were linear vs. ¦Ò_p^– values. A linear plot was obtained and explained for a plot of BDE of the N-H bonds in remotely substituted phenylsulfonylanilides with ¦Ò⁺ values. Plots of BDEs vs. E_ox(A^–) were also linear for 4-substituted phenylsulfenylanilides (4-GC₆H₄NHSPh), phenylsulfonylanilides (4-GC₆H₄NHSO₂Ph) and Ph benzyl sulfones (4-GC₆H₄CH₂SO₂Ph).

Journal of Physical Organic Chemistry published new progress about 19117-31-8. 19117-31-8 belongs to catalysis-chemistry, auxiliary class Oxidant, name is N-(tert-Butyl)-S-phenylthiohydroxylamine, and the molecular formula is C10H15NS, Recommanded Product: N-(tert-Butyl)-S-phenylthiohydroxylamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Li-juan published the artcileIsolation and identification of endophytic fungi from Lilium Siberia and analysis of volatile components, Recommanded Product: 2-Ethyl-N,N-dimethylhexan-1-amine, the publication is Shipin Gongye (Shanghai, China) (2013), 34(9), 203-205, database is CAplus.

Ten strains of endophytes were purified from the endophytes in fresh Lily. One of them was selected as a sample because of its fragrant metabolite and speedy growth. The metabolite was analyzed by GC-MS. The results showed that the main aroma components were alkenes, alcs., esters and alkyls, for example, 4-penten-2-ol (67.29%), 1,3-diazine (3.42%), 1,2-benzenedicarboxylic acid, bis(2-methylpropyl)ester (2.04%), 9,12-octadecadienoicacid (Z,Z) (1.72%), 1-butanol, 2-Me (1.38%), phenylethyl, alc. (1.53%), dibutylphthalate (1.22%), tetratriacontane (1.29%), and 4-heptanol (1.05%).

Shipin Gongye (Shanghai, China) published new progress about 28056-87-3. 28056-87-3 belongs to catalysis-chemistry, auxiliary class Amine,Aliphatic hydrocarbon chain, name is 2-Ethyl-N,N-dimethylhexan-1-amine, and the molecular formula is C11H12O4, Recommanded Product: 2-Ethyl-N,N-dimethylhexan-1-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kang, Kai published the artcileC(sp²)-C(sp²) Reductive Elimination from Well-Defined Diarylgold(III) Complexes, Product Details of C9H9F5Si, the publication is Organometallics (2017), 36(24), 4727-4740, database is CAplus.

Well-defined phosphine-ligated diarylgold(III) complexes cis-[Au(L)(Ar_F)(Ar’)(Cl)] were prepared and detailed kinetics of the C(sp²)-C(sp²) reductive elimination from these complexes were studied. The mechanism of the reductive elimination from complexes cis-[Au(L)(Ar_F)(Ar’)(Cl)] was further studied by theor. calculation The combination of exptl. and theor. results suggests that the biaryl reductive elimination from organogold(III) complexes cis-[Au(L)(Ar_F)(Ar’)(Cl)] proceeds through a concerted biaryl-forming pathway from the four-coordinated Au(III) metal center. These studies also disclose that the steric hindrance of the phosphine ligands plays a major role in promoting the biaryl-forming reductive elimination from diarylgold(III) complexes cis-[Au(L)(Ar_F)(Ar’)(Cl)], while electronic properties of these ligands have a much smaller effect. Furthermore, the complexes with more weakly electron-withdrawing aryl ligands undergo reductive elimination faster and the elimination rate is not sensitive to the polarity of the solvents.

Organometallics published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Product Details of C9H9F5Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia