Month: December 2022

Zemtsov, Artem A. published the artcileReactions of fluorinated silanes with 2-nitrocinnamates, Recommanded Product: Trimethyl(perfluorophenyl)silane, the publication is Journal of Fluorine Chemistry (2011), 132(6), 378-381, database is CAplus.

The interaction of ¦Á-nitrocinnamates with Me₃SiR_f (R_f = CF₃, C₂F₅, C₆F₅) promoted by NaOAc in DMF or by Bu₄NOAc in CH₂Cl₂ was described. The reactions proceeded as conjugate addition of the resp. fluorinated carbanion at the C:C bond and afforded 3-aryl-2-nitrobutanoic acid Me esters (aryl = Ph, 4-MeOC₆H₄, 2-furyl) bearing a fluorinated substituent in good yields as diastereomeric mixtures in ratios of 1:1 to 1.6:1. Subsequent hydrogenation led to amino acid esters.

Journal of Fluorine Chemistry published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9NO6S, Recommanded Product: Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zemtsov, Artem A. published the artcileReaction of Baylis-Hillman Adducts with Fluorinated Silanes, Application of Trimethyl(perfluorophenyl)silane, the publication is European Journal of Organic Chemistry (2010), 6779-6785, S6779/1-S6779/7, database is CAplus.

Reactions of acylated Baylis-Hillman adducts bearing nitrile, ester, or ketone groups with C₆F₅-substituted silicon reagents Me_nSi(C₆F₅)_4-n (n = 1-3) have been studied. The reactions are initiated by Bu₄NOAc (5 mol-%) in MeCN or DMF under mild conditions and afford products of allylic substitution of the acetoxy group by the C₆F₅ carbanion in good yields. Predominant or exclusive formation of one geometrical isomer was observed in all cases (Z for nitriles, E for esters and ketones). For substrates containing carbonyl groups, nucleophilic attack of the C₆F₅ carbanion chemoselectively occurred at the C=C bond. Reactions of acylated Baylis-Hillman adducts with Me₃SiCF₃ were found to be inefficient, as the CF₃ carbanion had the propensity to attack the C=O bond of substrates with ester or ketone substituents.

European Journal of Organic Chemistry published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C14H28O5S, Application of Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dilman, Alexander D. published the artcileNucleophilic trifluoromethylation of arylidenemalononitriles, COA of Formula: C9H9F5Si, the publication is Tetrahedron Letters (2008), 49(28), 4352-4354, database is CAplus.

A method for the nucleophilic trifluoromethylation of arylidenemalononitriles using Me₃SiCF₃ is described. The reaction is carried out in DMF in the presence of AcONa as a Lewis base, and affords Michael addition products in high yield.

Tetrahedron Letters published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, COA of Formula: C9H9F5Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dilman, Alexander D. published the artcileSynthesis of C₆F₅-substituted amines containing quaternary carbon atoms, Synthetic Route of 1206-46-8, the publication is Synthesis (2006), 447-450, database is CAplus.

The reaction of enamines and methyltris(pentafluorophenyl)silane in the presence of acetic acid affording C₆F₅-substituted amines is described. The proposed mechanism features a transfer of the C₆F₅ group from the five-coordinate silicate intermediate onto an iminium cation resulting in the generation of a quaternary carbon atom in the C-C bond forming event.

Synthesis published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Synthetic Route of 1206-46-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rothen, Alexandre published the artcileRotatory dispersion and absorption spectra of carboxylic acids and hydrocarbons containing a phenyl or a cyclohexyl group, Formula: C11H14O2, the publication is Journal of Chemical Physics (1939), 975-83, database is CAplus.

Maximum optical rotations are tabulated for (a) MeCHRCOOH, (b) MeCHRCH₂COOH, (c) EtCHRCOOH, (d) PrCHPhCH₂COOH, (e) EtCHPhBu, (f) RCH₂CHMeCOOH, (g) RCH₂CHMeCH₂COOH, (h) PhCH₂CHMeEt, (i) RCH₂CH₂CHMeCOOH, (j) RCH₂CH₂CHMeCH₂COOH, (k) PhCH₂CH₂CHMeCH₂CH₂COOH, (l) cyclo-C₆H₁₁CH₂CH₂CHMeCH₂CH₂COOH, (m) RCH₂CH₂CHMeCH₂CH₂CH₂COOH, (n) PhCH₂CH₂CHMeEt, where R = Ph, cyclo-C₆H₁₁ or C₆H₁₃. Calculated and observed rotatory dispersions are compared at 3-23 wave lengths between 2300 and 6700 A. for solutions in heptane of all the Ph compounds except a, and the cyclohexyl compounds a, b, c, f and g; and for the cyclohexyl compounds i, j, l and m and for e, h and n: rotatory dispersions are plotted (1/¦Á against ¦Ë²) for the Ph compounds b, f and m, and for cyclohexyl compounds a, f and i; the maximum mol. rotations are plotted against ¦Ë¦Ë (3900-6300) for cyclo-C₆H₁₁CHEtCOOH. Absorption spectra are plotted ¦Ë¦Ë (2200-2800) for the Ph compounds b, c, f, i, j, m and n; for the cyclohexyl compounds a, l and m; and for PhCHMeBu. Absorption bands (5-7 each) of PhCH₂CONH₂, Ph(CH₂)₆CONH₂, PhMeCHCOOH, PhCH₂CH₂CHMeCOOH and PhCH₂CH₂CHMeCH₂COOH are compared. Shifts in the absorption bands of these disubstituted carboxylic acids were studied as a function of the Phú´COOH distance. The first absorption region of the Ph group furnishes no detectable rotatory contribution in this type of acid. The first rotatory contribution is allocated to the COOH group. The Ph and cyclohexyl groups have a vicinal effect similar to that of the hexyl group with respect to the sign of rotation.

Journal of Chemical Physics published new progress about 1949-41-3. 1949-41-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene, name is 2-Methyl-4-phenylbutanoic acid, and the molecular formula is C11H14O2, Formula: C11H14O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Seeling, Andreas published the artcilePhysico-chemical, pharmacological, and toxicological properties of fomocaine metabolites, Category: catalysis-chemistry, the publication is Arzneimittel-Forschung (2001), 51(1), 7-17, database is CAplus and MEDLINE.

Fomocaine (4-[3-(4-phenoxymethylphenyl)-propyl]-morpholine, CAS 17692-39-6) is a highly effective local anesthetic of low toxicity. The drug, which causes no allergic response, was introduced in the German Extrapharmacopoeia (DAC). 14 Metabolites are formed after oral administration to rat and beagle dog. Less than 5 % fomocaine are excreted unchanged. The metabolites were synthesized and their physico-chem. properties were investigated. No metabolite caused a surface or conduction anesthesia with the exception of 2-hydroxyfomocaine (O/Se 4). After topical and parenteral administration irritation could not be observed All metabolites except O/Se 10 and O/Se 11 showed a lower toxicity than fomocaine. In both species O/Se 10 and O/Se 11 are formed only in a small amount and are detoxified by conjugation.

Arzneimittel-Forschung published new progress about 31719-76-3. 31719-76-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 4-(Phenoxymethyl)benzoic acid, and the molecular formula is C9H5ClO4S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Krieger, Jean-Philippe published the artcileRhodium(III)-Catalyzed C-H Activation/Heterocyclization as a Macrocyclization Strategy. Synthesis of Macrocyclic Pyridones, Synthetic Route of 1293990-73-4, the publication is Organic Letters (2017), 19(10), 2706-2709, database is CAplus and MEDLINE.

Structurally diverse macrocyclic pyridones can be efficiently synthesized by a rhodium(III)-catalyzed C-H activation/heterocyclization of ¦Ø-alkynyl ¦Á-substituted acrylic hydroxamates. The use of a O-pivaloyl hydroxamate as directing group was crucial to achieve efficient catalyst turnover in a redox-neutral process.

Organic Letters published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Synthetic Route of 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hu, Xianbo published the artcileEffect of a silicate filler on the crystal morphology of poly(trimethylene terephthalate)/clay nanocomposites, HPLC of Formula: 28056-87-3, the publication is Journal of Polymer Science, Part B: Polymer Physics (2003), 41(19), 2275-2289, database is CAplus.

A series of intercalated poly(trimethylene terephthalate) (PTT)/clay nanocomposites were prepared in a twin-screw extruder by the melt mixing of PTT with either quaternary or ternary ammonium salt-modified clays. The morphol. and structure, along with the crystallization and melting behavior, and the dynamic mech. behavior of the composites were characterized by X-ray diffraction, transmission electron microscopy, differential scanning calorimetry, and dynamic mech. thermal anal. The results showed that the PTT chains could undergo center-mass transport from the polymer melt into the silicate galleries successfully during the blending and extrusion process. More coherent stacking of the silicate layers was reserved at higher clay concentrations and shorter blend times. Compared with conventionally compounded composites, the nanoscale-dispersed organophilic clays were more effective as crystal nucleation agents. The influence of the nano-silicates on the crystallization and melting behavior of PTT became distinct when the concentration of clay was around 3 wt%. The changes in the crystallization behavior of the polymer/clay nanocomposites depended not only on the size of the silicates but also on the intrinsic crystallization characteristics of the polymers. The resulting nanocomposites showed an increase in the dynamic modulus of PTT and a decrease in the relaxation intensity (both in loss modulus and loss tangent magnitude).

Journal of Polymer Science, Part B: Polymer Physics published new progress about 28056-87-3. 28056-87-3 belongs to catalysis-chemistry, auxiliary class Amine,Aliphatic hydrocarbon chain, name is 2-Ethyl-N,N-dimethylhexan-1-amine, and the molecular formula is C10H23N, HPLC of Formula: 28056-87-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Faivre-duPaigre, Roger published the artcileMorphological modifications produced in Italian ryegrass by 2,4-dichlorophenoxyacetic acid (2,4-D), 2-methyl-4-chlorophenoxyacetic acid (MCPA), and 2-methyl-4-chlorophenoxybutyric acid (MCPB), Product Details of C12H16O3, the publication is Compt. rend. (1961), 3107-9, database is CAplus.

Application of 1, 2, 5, or 10 kg./hectare of 2,4-D, MCPA, or MCPB to Lolium italicum after tillering produces anomalous growth of stems and heads. Stems show aberrant tillering at the base of the plants and at internodes, and curvature of nodes and internodes. Rachises may be bi- or trifurcated, elongated or shortened, or have spiral or sinuate conformations. Spikelets may vary in point of attachment, may be pedicellate, compound, or sterile. A single plant may show any or all of these modifications.

Compt. rend. published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Product Details of C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Della Monica, Francesco published the artcileCO₂ cycloaddition to epoxides promoted by bis-thioether-phenolate Fe(II) and Fe(III) complexes, SDS of cas: 22693-41-0, the publication is Molecular Catalysis (2018), 46-52, database is CAplus.

The synthesis and characterization of three new bis-thioether-phenolate monoanionic tridentate [SOS]-type ligands, and the synthesis of the corresponding Fe(II) and Fe(III) complexes are reported. Their application, in combination with tetrabutylammonium bromide (TBAB), as catalysts for the cycloaddition of CO₂ to a number of monosubstituted epoxides and cyclohexene oxide was investigated. For example, epichlorohydrin is converted in the corresponding cyclic carbonate, with a turnover frequency of 155 h^-1 (0.1 mol% of iron, 0.5 mol% of TBAB, 10 bar of CO₂). With the aim to obtain further information about the catalyst structure-activity relationship and the reaction mechanism, the reaction between the catalyst precursors and TBAB was investigated, suggesting the formation of an anionic metalate species in the case of the Fe(III) complexes that is supposed to be true catalyst. A mechanistic scenario explaining the different behavior of the Fe(II) and Fe(III) complexes is proposed.

Molecular Catalysis published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, SDS of cas: 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia