Month: December 2022

Kim, Dahham published the artcileTwo-Photon and Multicolor Fluorogenic Bioorthogonal Probes Based on Tetrazine-Conjugated Naphthalene Fluorophores, HPLC of Formula: 1466420-02-9, the publication is Bioconjugate Chemistry (2020), 31(5), 1545-1550, database is CAplus and MEDLINE.

Herein, we report the use of two-photon fluorogenic probes using tetrazine-based bioorthogonal reactions with multicolor emissions that cover nearly all of the visible region. New fluorogenic probes were designed based on donor-acceptor-type naphthalene structures conjugated with a fluorescence-quenching tetrazine moiety for turn-on properties in one- and two-photon fluorescence. Our fluorescent probes showed a moderate to good turn-on ratio after bioorthogonal inverse electron demand Diels-Alder cycloaddition with trans-cyclooctenol in one- and two-photon fluorescence. We successfully applied our probes to mitochondria- and lysosome-selective bioorthogonal imaging in live cells with one-/two-photon and one-photon microscopy, resp.

Bioconjugate Chemistry published new progress about 1466420-02-9. 1466420-02-9 belongs to catalysis-chemistry, auxiliary class Copper-Free Click Chemistry,Tetrazine, name is (4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl)methanamine trifluoroacetic acid, and the molecular formula is C12H12F3N5O2, HPLC of Formula: 1466420-02-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chang, Ying published the artcileDirect fluorination of the carbonyl group of benzophenones using Deoxo-Fluor: preparation of bis(4-fluorophenyl)difluoromethane, Related Products of catalysis-chemistry, the publication is Organic Syntheses (2010), 245-252, database is CAplus.

The synthesis of the target compound was achieved by a reaction of bis(4-fluorophenyl)methanone (benzophenone derivative) trifluoro[2-methoxy-N-(2-methoxyethyl)ethanaminato-¦ÊN]sulfur (i.e., Deoxo-Fluor).

Organic Syntheses published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chae, Weon-Sik published the artcileMolecular sensing efficiency of gold-silver alloy nanowires, Computed Properties of 10510-54-0, the publication is Bulletin of the Korean Chemical Society (2011), 32(4), 1346-1348, database is CAplus.

The SERS efficiency for the AuAg alloy nanowires was estimated The nanowire were prepared by electrodeposition using anodic aluminum oxide hard templates. The estimated SERS efficiency for the alloy nanowires was comparable to the porous Au nanowires, and both the nanowires showed definitely higher mol. sensing activity than the dense Au nanowires. This result means that 1D AuAg alloy nanomaterials would be excellent SERS substrates.

Bulletin of the Korean Chemical Society published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Computed Properties of 10510-54-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bunce, Richard A. published the artcileEster- and ketone-substituted (¡À)-1-alkyl-6-nitro-1,2,3,4-tetrahydroquinolines by a tandem S_NAr-Michael reaction, Safety of N-Benzyl-2-methyl-4-nitroaniline, the publication is Journal of Heterocyclic Chemistry (2010), 47(5), 1176-1182, database is CAplus.

A synthesis of ester- and ketone-substituted (¡À)-1-alkyl-6-nitro-1,2,3,4-tetrahydroquinolines was developed from 2-pentenoates and 2-penten-1-ones, resp., substituted at C(5) by a 2-fluoro-5-nitrophenyl group. The cyclization involves an S_NAr reaction followed by a Michael addition that occurs exo to the final ring. A previously reported version of this annulation proceeded by an initial endo Michael addition (acceptor became part of the final ring) followed by an S_NAr ring closure. The current reactions proceed in 82-97% yields in DMSO using primary amines that are unbranched at the ¦Á C. The synthesis of the reaction substrates as well as process optimization, mechanistic studies to elucidate the reaction chronol., and comparisons with the endo Michael variant are presented.

Journal of Heterocyclic Chemistry published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C14H14N2O2, Safety of N-Benzyl-2-methyl-4-nitroaniline.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Pshezhetskii, V. S. published the artcileRole of the cofactor in catalysis on macromolecular models of catalase, Application of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Doklady Akademii Nauk SSSR (1972), 204(6), 1492-5 [Biochem], database is CAplus.

The effects of the presence of H2O2 on the form of titration curves of HCl salts of H2NCH2CH2NH2, triethylenetetramine, BuNH2, and Me2NCH2CH2NMe2 were described graphically. Reduction of basicity of the 1st 2 amines was noted in the presence of H2O2 owing to formation of a complex between the reactants. The tertiary amines do not exhibit this behavior and do not form such a complex. The kinetic equations for complex formation were drawn up in general terms and applied to the specific cases above. Catalyzed decomposition of H2O2 over polymeric metal-containing complexes of polyacrylic and polymethacrylic acids in the presence of the 1st 2 amines was discussed. It was concluded that this consists of the interaction of the 2 complexes of H2O2 with the amines with the possibility of forming 2 H bonds between them. The order of such reactions is variable and dependent on pH as this affects the concentration of HO2-, which, along with the H2O2 complexes, undergo catalytic decomposition on the polymeric complexes. Rate constants were reported for decomposition of H2O2 on polymers of the above types in the presence of the 2 active amines and Fe(III).

Doklady Akademii Nauk SSSR published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Application of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Schmink, Jason R. published the artcilePalladium-Catalyzed Synthesis of Diarylmethanes: Exploitation of Carbanionic Leaving Groups, Product Details of C13H10F2, the publication is Organic Letters (2009), 11(12), 2575-2578, database is CAplus and MEDLINE.

A novel route to the synthesis of diarylmethanes via a Pd-catalyzed ¦Á-arylation of benzyl ketones is reported. By harnessing the inherent reactivity of enolates, it is possible to circumvent the need for a transmetalating reagent such as boron for the coupling. Addnl., the two Ph rings of the intermediate are exploited to stabilize the high-energy carbanionic leaving group in a straightforward synthesis.

Organic Letters published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Product Details of C13H10F2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nguyen, Hai Truong published the artcileIntermolecular and Intramolecular Friedel-Crafts Acylation of Carboxylic Acids using Binary Ionic Liquids: An Experimental and Computational Study, Recommanded Product: 2-Methylbenzoic acid, the publication is ChemistrySelect (2022), 7(2), e202103708, database is CAplus.

In this study, the desired products 2-RC₆H₄C(O)R¹ (R = H, Br, Cl, F, Me; R¹ = 4-methoxyphenyl, naphthalen-2-yl, 1H-indol-3-yl, etc.) were obtained at moderate to good yields under microwave irradiation for a short reaction time. The Friedel-Crafts cyclization of 4-phenylbutyric acid is more effective than 3-phenylpropionoic acid under the present method. The reaction mechanism is proposed by combining experiments with d. functional theory calculations, highlighting the critical role of ZnCl₂, triflate anion (CF3COO-) in binary ionic liquids, and acidic conditions in accommodating a kinetic accessible pathway making the C-C bond.

ChemistrySelect published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Recommanded Product: 2-Methylbenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Dejiang published the artcileNickel- and Palladium-Catalyzed Cross-Coupling Reactions of Organostibines with Organoboronic Acids, Recommanded Product: 4,4′-Dimethyldiphenyl, the publication is Angewandte Chemie, International Edition (2021), 60(6), 3104-3114, database is CAplus and MEDLINE.

A strategy for the formation of antimony-carbon bond was developed by nickel-catalyzed cross-coupling of halostibines. This method has been applied to the synthesis of various triaryl- and diarylalkylstibines from the corresponding cyclic and acyclic halostibines. This protocol showed a wide substrate scope (72 examples) and was compatible to a wide range of functional groups such as aldehyde, ketone, alkene, alkyne, haloarenes (F, Cl, Br, I), and heteroarenes. A successful synthesis of one arylated stibine in a scale of 34.77 g demonstrates high synthetic potential of this transformation. The formed stibines (R₃Sb) were then used for the palladium-catalyzed carbon-carbon bond forming reaction with aryl boronic acids [R-B(OH)₂], giving biaryls with high selectivity, even the structures of two organomoieties (R and R’) are very similar. Plausible catalytic pathways were proposed based on control experiments

Angewandte Chemie, International Edition published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C9H12O, Recommanded Product: 4,4′-Dimethyldiphenyl.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Feeny, Rachel M. published the artcileSultam thioureas: synthesis and antiviral activity against West Nile virus, Category: catalysis-chemistry, the publication is Synlett (2012), 23(2), 301-305, database is CAplus.

The syntheses of eleven sultam thioureas, including nine new compounds, are described. These compounds were synthesized from thioureas and include the first sultam thioureas in which the two thiourea nitrogen groups are not identical. In addition, the first X-ray crystal structures of sultam thioureas and the antiviral activity of these compounds against West Nile virus (WNV) are reported.

Synlett published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Santoro, Orlando published the artcileN-heterocyclic carbene copper(I) catalysed N-methylation of amines using CO₂, HPLC of Formula: 2909-77-5, the publication is Dalton Transactions (2015), 44(41), 18138-18144, database is CAplus and MEDLINE.

The N-methylation of amines using CO₂ and PhSiH₃ as source of CH₃ was efficiently performed using a N-heterocyclic carbene copper(I) complex. The methodol. was found compatible with aromatic and aliphatic primary and secondary amines. Synthetic and computational studies have been carried out to support the proposed reaction mechanism for this transformation.

Dalton Transactions published new progress about 2909-77-5. 2909-77-5 belongs to catalysis-chemistry, auxiliary class Amine,Benzene, name is 2,6-Diisopropyl-N,N-dimethylaniline, and the molecular formula is C14H23N, HPLC of Formula: 2909-77-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia