Catalysis-chemistry

Lyu, Zhigang published the artcileSteric-free bioorthogonal labeling of acetylation substrates based on a fluorine-thiol displacement reaction, Recommanded Product: 2,4,6-Trimethoxybenzenethiol, the publication is Journal of the American Chemical Society (2021), 143(3), 1341-1347, database is CAplus and MEDLINE.

We have developed a novel bioorthogonal reaction that can selectively displace fluorine substitutions alpha to amide bonds. This fluorine-thiol displacement reaction (FTDR) allows for fluorinated cofactors or precursors to be utilized as chem. reporters, hijacking acetyltransferase-mediated acetylation both in vitro and in live cells, which cannot be achieved with azide- or alkyne-based chem. reporters. The fluoroacetamide labels can be further converted to biotin or fluorophore tags using FTDR, enabling the general detection and imaging of acetyl substrates. This strategy may lead to a steric-free labeling platform for substrate proteins, expanding our chem. toolbox for functional annotation of post-translational modifications in a systematic manner.

Journal of the American Chemical Society published new progress about 77189-99-2. 77189-99-2 belongs to catalysis-chemistry, auxiliary class Thiophenol,Benzene,Ether, name is 2,4,6-Trimethoxybenzenethiol, and the molecular formula is C9H12O3S, Recommanded Product: 2,4,6-Trimethoxybenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huang, Yong-Qing published the artcileOne-pot synthesis of imidazolinium salts via the ring opening of tetrahydrofuran, SDS of cas: 140-28-3, the publication is Dalton Transactions (2017), 46(37), 12430-12433, database is CAplus and MEDLINE.

A new one-pot synthesis of C2-hydroxypropyl-substituted imidazolinium salts I (R = Me, benzyl, 4-hydroxybenzyl, etc.; n = 1, 2) via the ring opening of THF with N,N’-disubstituted diamines such as N,N’-dibenzylideneethane-1,2-diamine, N,N’-bis(4-dimethylaminobenzylidene)ethane-1,2-diamine, N,N’-bis(4-hydroxybenzylidene)ethane-1,2-diamine, etc. has been developed. Preliminary studies of the reaction mechanism suggest the CO₂-promoted oxidative ring opening of THF followed by Hg(II)-mediated oxidation of an imidazolidine intermediate. These novel C2-substituted imidazolinium salts I have shown to be active catalysts for the aza-Diels-Alder reactions.

Dalton Transactions published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, SDS of cas: 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Rui published the artcileTris Chelating Phosphate Complexes of Bis(thio)urea Ligands, SDS of cas: 17351-61-0, the publication is Inorganic Chemistry (2013), 52(10), 5851-5860, database is CAplus and MEDLINE.

Two bisurea (L¹, L²) and one bisthiourea (L³) ligands were synthesized and their anion coordination behavior was studied. These ligands can readily form the tris chelates [PO₄(L)₃]^3- (1, 5, and 6) with phosphate ion (PO₄^3-) in the solid state, in which the anion is coordinated by six urea groups through 12 hydrogen bonds. Solution binding studies by ¹H NMR and UV-visible spectroscopy revealed different binding properties of the ligands toward phosphate ion. While the bis(p-nitrophenyl)-substituted bisurea L¹ retains the 3:1 (host to guest) binding ratio in solution, the di-Et derivative L² only forms 1:1 complex with phosphate ion. The more acidic thiourea L³ undergoes deprotonation/decomposition in the presence of phosphate ion. Also, the sulfate complex (2) of L¹ and bicarbonate (3) and carbonate (4) complexes of L² also were obtained, which show lower coordination numbers both in the solid state and in solution

Inorganic Chemistry published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C9H21NO3, SDS of cas: 17351-61-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ma, Yuan-Yuan published the artcilePrediction of freestanding semiconducting bilayer borophenes, Related Products of catalysis-chemistry, the publication is Nano Research (2022), 15(6), 5752-5757, database is CAplus.

Supported bilayer ¦Á-borophene (BL-¦Á borophene) on Ag(111) substrate has been synthesized in recent experiments Based on the exptl. observed quasi-planar C_6v B₃₆ (1), its monolayer assembly ¦Á+-borophene B11 (P6/mmm) (2), and extensive global min. searches augmented with d. functional theory calculations, we predict herein freestanding BL-¦Á+ borophenes B22 (Cmmm) (3) and B22 (C2/m) (4) which, as the most stable BL borophenes reported to date, are composed of interwoven boron triple chains as boron analogs of monolayer graphene (5) consisting of interwoven carbon single chains. The nearly degenerate eclipsed B22 (3) and staggered B22 (4) with the hexagonal hole d. of ¦Ç = 1/12 and interlayer bonding d. of u = 1/4 appear to be two-dimensional semiconductors with the indirect band gaps of 0.952 and 1.144 eV, resp. Detailed bonding analyses reveal one delocalized 12c-2e ¦Ð bond over each hexagonal hole in both the B22 (3) and B22 (4), similar to the situation in monolayer graphene which contains one delocalized 6c-2e ¦Ð bond over each C6 hexagon. Furthermore, these BL-¦Á+ borophenes appear to remain highly stable on Ag(111) substrate, presenting the possibility to form supported BL-¦Á+ borophenes.

Nano Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Jingjing published the artcileDiazaphospholene-Catalyzed Hydrodefluorination of Polyfluoroarenes with Phenylsilane via Concerted Nucleophilic Aromatic Substitution, Category: catalysis-chemistry, the publication is Journal of Organic Chemistry (2022), 87(1), 294-300, database is CAplus and MEDLINE.

The metal-free catalytic C-F bond activation of polyfluoroarenes was achieved with diazaphospholene as the catalyst and phenylsilane as the terminal reductant. D. functional theory calculations suggested a concerted nucleophilic aromatic substitution mechanism.

Journal of Organic Chemistry published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C10H10O2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yu, Shuo-Wen published the artcileConstruction of Novel Kojic Acid Fused Furans by Domino Reactions of a Kojic Acid Derivative with (Z)-Bromonitroalkenes, Category: catalysis-chemistry, the publication is ChemistrySelect (2018), 3(17), 4827-4830, database is CAplus.

A series of novel kojic acid fused furans I (R = Ph, 1-naphthyl, 2-thienyl, etc.) have been synthesized by domino cyclization-elimination reactions of a kojic acid derivative with (Z)-bromonitroalkenes. In the presence of a bifunctional thiourea-tertiary amine organocatalyst and sodium bicarbonate, the reactions provided the products in up to quant. yields.

ChemistrySelect published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C5H11NO2S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huang, Zhen published the artcileSelective removal mechanism of novel Zr-based metal organic framework adsorbents for gold ions from aqueous solutions, Product Details of C14H10O4S2, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2020), 123343, database is CAplus.

A novel metal organic framework absorbent was synthesized by one step method using 2,2′-dithiodibenzoic acid as organic linker for efficient and selective recovery of Au(III) from aqueous solution The adsorbent were detected by scanning electron microscope, X-ray diffraction and zeta potential instruments. Its performance was tested by batch experiments The adsorption isotherm conforms to the Langmuir model, demonstrating that the adsorption process is the uniform monolayer adsorption. The kinetic model is well fitted to the pseudo second-order dynamics model. The maximum adsorption capacity was 1119 mg/g at pH = 2. High temperatures can promote the absorption process. The five adsorption and desorption cycles indicate that the adsorbent has good repeatability for Au(III) adsorption. It could selectively adsorbed Au(III) from wastewater. The adsorption derive from chelation and reduction The DFT and XPS results show that Au(III) is mainly adsorbed on the adsorbent by coupling with the S atom. These results indicate that it has a high potential to remove Au(III) from industrial wastewater.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Product Details of C14H10O4S2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Zhiqing published the artcileInvestigation of oyster Crassostrea gigas lipid profile from three sea areas of China based on non-targeted lipidomics for their geographic region traceability, Safety of Docosahexaenoic Acid, the publication is Food Chemistry (2022), 132748, database is CAplus and MEDLINE.

The present study sought to analyze the lipid profiles of oyster Crassostrea gigas from Yellow Sea (YS), East China Sea, and South China Sea (SCS) through the untargeted lipidomics strategy based on UPLC-Q-Exactive Orbitrap mass spectrometry and multivariate statistics. The results elucidated that geog. differences had profound effects on the lipid content, composition, and lipid mol. profiles. Notably, oysters from the YS group contained the highest lipid content, including triacylglycerol, diacylglycerols, and the majority of phospholipid mol. species, while oysters from the ECS group contained most of the phosphatidylcholine species and the SCS group contained most of the sphingolipid species. Totally, 1155 lipid mol. species belonging to 21 subclasses were identified; of them, 45 lipid mol. species could serve as differential marker for lipid of oysters from different sea areas. Overall, lipidomics could be a potential approach for discrimination of lipid characters between marine shellfishes for geog. origin traceability.

Food Chemistry published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Safety of Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Qing published the artcileSynthesis and biological evaluation of diaryl urea derivatives as FLT3 inhibitors, Related Products of catalysis-chemistry, the publication is Bioorganic & Medicinal Chemistry Letters (2020), 30(23), 127525, database is CAplus and MEDLINE.

As a class III receptor tyrosine kinase (RTK), FMS-like tyrosine kinase 3 (FLT3) is always overexpressed in many cases of acute leukemia. This paper studies the structure-based synthesis and biol. evaluation of diaryl urea derivatives as FLT3 inhibitors. Encouragingly, compounds 1-(3-(tert-butyl)isoxazol-5-yl)-3-(4-(7-methoxybenzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea , 1-(3-(tert-butyl)isoxazol-5-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea , 1-(5-(tert-butyl)isoxazol-3-yl)-3-(2-(4-(2-morpholinoethoxy)phenyl)benzo[d]imidazo[2,1-b]thiazol-7-yl)urea , and 1-(3-(tert-butyl)isoxazol-5-yl)-3-(2-(4-(2-morpholinoethoxy)phenyl)benzo[d]imidazo[2,1-b]thiazol-7-yl)urea showed excellent biol. activities in a low nanomolar range. In particular, compound 1-(3-(tert-butyl)isoxazol-5-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea demonstrated significant inhibitory potency against FLT3-ITD (IC₅₀ = 5.60 nM) and better antiproliferative activity than quizartinib against MV4-11 cell line (IC₅₀ = 0.176 nM). Compound 1-(3-(tert-butyl)isoxazol-5-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea for the treatment of acute myeloid leukemia could be very promising.

Bioorganic & Medicinal Chemistry Letters published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C5H6BNO2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Zhangtie published the artcileImpact of interactions between whey protein isolate and different phospholipids on the properties of krill oil emulsions: A consideration for functional lipids efficient delivery, Computed Properties of 6217-54-5, the publication is Food Hydrocolloids (2022), 107692, database is CAplus.

The interactions between different phospholipids (yolk phospholipid, soybean phospholipid, and perilla seed phospholipid) and whey protein isolate (WPI) were studied. Phys. characteristics and bioaccessibility of different emulsions were compared. According to the results of multiple spectroscopy, isothermal titration calorimetry (ITC), and mol. docking, hydrophobic interactions played an important role in the interaction of phospholipid and WPI, enhanced as more unsaturation Dynamic light scattering showed that combination of phospholipids and proteins could decrease particle sizes (from 232.33 ¡À 4.79 nm to 188.59 ¡À 2.61 nm) and improve emulsion stability significantly (from -34.26 ¡À 1.31 mV to -49.13 ¡À 1.91 mV), presenting dose-dependency. Microstructure results indicated that phospholipids would contribute to dispersity and homogeneity of emulsions. Furthermore, the phospholipid-WPI emulsion can be an efficient tool for functional lipid delivery and improving the functional lipid ratios in the zebrafish model. Compared to WPI emulsions, the phospholipid-WPI emulsion group exhibited higher ratios of functional lipids in zebrafish fatty acid compositions (up to 29.41% ¡À 0.87%). In vitro digestion supported that perilla seed phospholipid-WPI emulsions would contribute to a higher bioaccessibility of EPA (from 36.59% ¡À 0.88%-53.08% ¡À 0.96%), DHA (from 36.42% ¡À 1.03%-54.10% ¡À 1.07%) and astaxanthin (from 31.54% ¡À 2.52%-53.31% ¡À 4.05%). Overall, our research can be useful to an efficient delivery system for functional lipids with phospholipid-protein structures.

Food Hydrocolloids published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C15H21BO2, Computed Properties of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia