Catalysis-chemistry

Nishida, Masakazu published the artcileFormation of perfluorinated polyphenylenes by multiple pentafluorophenylation using C₆F₅Si(CH₃)₃, Synthetic Route of 1206-46-8, the publication is Journal of Fluorine Chemistry (2010), 131(12), 1314-1321, database is CAplus.

Pentafluorophenylation of perfluoroarenes with C₆F₅Si(CH₃)₃ was investigated by using NMR and MALDI-TOF-MS techniques. Successive multiple pentafluorophenylation easily occurred not only on the para-position but also on the ortho-positions to provide perfluorinated p-phenylene and m-phenylene compounds The perfluoroarenes having electron-withdrawing substituents provided oligo- to poly-(phenylene)s depending on the added amounts of C₆F₅Si(CH₃)₃, while the perfluoroarenes having electron-donor substituents gave H(C₆F₄)_nF polymers produced from C₆F₅H, which was the decomposed product of C₆F₅Si(CH₃)₃.

Journal of Fluorine Chemistry published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Synthetic Route of 1206-46-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kitagawa, Motoji published the artcilePancreatic and biliary excretion of camostat in dogs, COA of Formula: C17H19N3O7S, the publication is Digestion (1988), 39(4), 204-9, database is CAplus and MEDLINE.

To confirm whether camostat (Foy-305) is excreted into bile or pancreatic juice, camostat (5 mg/kg/h) was given i.v. to dogs with pancreatic or biliary fistulae. Camostat and its active metabolite (Foy-251) (I) in bile and pancreatic juice were measured by HPLC and by their trypsin-inhibitory activity. Camostat did not alter the exocrine pancreatic secretion of fluid, bicarbonate, protein or trypsin stimulated by secretin and caerulein. Camostat and its active metabolite were detected in bile by HPLC and trypsin-inhibitory activity (the mean excretion rate was 1.3% of the i.v. dose of camostat), but they were not detectable in pancreatic juice. In conclusion, camostat and its active metabolite were excreted into bile but not into pancreatic juice.

Digestion published new progress about 71079-09-9. 71079-09-9 belongs to catalysis-chemistry, auxiliary class Salt,Carboxylic acid,Carbamidine,Amine,Benzene,Ester,Protease,Ser/Thr Protease, name is 2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt, and the molecular formula is C17H19N3O7S, COA of Formula: C17H19N3O7S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Marling, J. B. published the artcileLasing characteristics of seventeen visible-wavelength dyes using a coaxial-flashlamp-pumped laser, Product Details of C18H15N3O3, the publication is Applied Optics (1974), 13(10), 2317-20, database is CAplus and MEDLINE.

The performance and tuning characteristic of organic dye lasers were measured using com. available coaxial flashlamps as the pumping source. Tuning by a diffraction grating permitted continuous coverage of the 4200-7500-? region at up to 0.6% tuned output energy efficiency. Preliminary results with a 600-J Marx-Bank coaxial laser at 4500 ? show 1% efficiency and single-pass unsaturated gain >20 at 4500 ?.

Applied Optics published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Product Details of C18H15N3O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Laufer, Stefan published the artcileTri- and tetra-substituted imidazoles as p38¦Á mitogen-activated protein kinase inhibitors, Application of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2010), 20(22), 6671-6675, database is CAplus and MEDLINE.

The synthesis of 2,4,5-tri-substituted and 1,2,4,5-tetra-substituted imidazoles, e.g. I, as potent p38¦Á mitogen-activated protein kinase inhibitors is described. The tri-substituted imidazole series was found to be more potent than the tetra-substituted imidazole series. Many of these compounds show low-nanomolar activities in the isolated p38¦Á MAP kinase inhibition assay. The structure-activity relationships between these two series are different and not comparable.

Bioorganic & Medicinal Chemistry Letters published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Application of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nguyen, Vu T. published the artcilePhotocatalytic decarboxylative amidosulfonation enables direct transformation of carboxylic acids to sulfonamides, Name: 3-Benzoylpropionicacid, the publication is Chemical Science (2021), 12(18), 6429-6436, database is CAplus and MEDLINE.

A visible light-induced, dual catalytic platform that for the first time allows for a one-step access to sulfonamides RS(O)₂R¹ (R = 4,4-dimethylcyclohexyl, heptadecyl, 4-oxo-4-phenylbutyl, etc.; R¹ = 2,3-dihydro-1H-indol-1-yl, (3,4,5-trimethylphenyl)aminyl, morpholin-4-yl, etc.) and sulfonyl azides R²S(O)₂N₃ (R² = 5-methoxy-5-oxopentyl, 4-(5-methylthiophen-2-yl)-4-oxobutyl, oxan-4-yl, etc.) directly from carboxylic acids R/R²COOH was reported. The broad scope of the direct decarboxylative amidosulfonation (DDAS) platform is enabled by the efficient direct conversion of carboxylic acids to sulfinic acids that are catalyzed by acridine photocatalysts and interfaced with copper-catalyzed sulfur-nitrogen bond-forming cross-couplings with both electrophilic and nucleophilic reagents.

Chemical Science published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C10H10O3, Name: 3-Benzoylpropionicacid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Masui, Yoichi published the artcileReversible Generation of Labile Secondary Carbocations from Alcohols in the Nanospace of H-Mordenite and Their Long-Lasting Preservation at Ambient Temperature, Product Details of C13H10F2, the publication is Journal of the American Chemical Society (2017), 139(25), 8612-8620, database is CAplus and MEDLINE.

Secondary carbocations are rarely observed spectrometrically for prolonged durations at ambient temperatures because of their instability. In this study, when 4,4′-difluorobenzhydrol (1) was mixed with H-mordenite (H-Mor), the 4,4′-difluorodiphenylmethyl cation (2) was generated as the main product, identified by UV-vis and ¹³C-MAS NMR spectroscopies, and was preserved for over 1 wk at ambient temperature Surprisingly, the polymerization and disproportionation of 1 barely proceeded within the micropores of H-Mor. However, these side reactions prevailed in TfOH and formation of 2 was not observed Preservation of other secondary carbocations from benzhydrol, 4,4′-dichlorobenzhydrol, and 9-fluorenol was also realized in H-Mor. It was confirmed that the generation of 2 from 1 was controlled by thermodn. equilibrium rather than kinetic regulations. The equilibrium between 2 and 1 was accompanied by reversible chromism, which could be easily controlled by altering the moisture content in H-Mor. Moreover, novel insights into specific acid catalysis in zeolites densely populated with acid sites on the inner surface of micropores are described herein.

Journal of the American Chemical Society published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Product Details of C13H10F2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nakamura, Ryuji published the artcileOral camostat mesilate administration on alkaline reflux esophagitis in an experimental animal model, Synthetic Route of 71079-09-9, the publication is Iwate Igaku Zasshi (1999), 50(Suppl.), 653-659, database is CAplus.

Following total gastrectomy and esophagojejunostomy in an end-to-side fashion, tabs of a synthetic proteinase inhibitor, camostat mesilate, were fed to 15 dogs via cervical esophagostomy. A 67% decrease in trypsin activity was observed in duodenal juice aspirated 30 min after administration. The suppression lasted 90 min. Administration of camostat 3 times per day for 2 wk (n = 5) failed to significantly improve erosive esophagitis noted by esophagoscopy, although a tendency of hemostasis of hemorrhagic erosion has been induced. In postoperative alk. reflux esophagitis, oral camostat administration alone is insufficient to protect the esophageal mucosa. Bile acid or other constituents of reflux must also be neutralized to improve the clin. condition.

Iwate Igaku Zasshi published new progress about 71079-09-9. 71079-09-9 belongs to catalysis-chemistry, auxiliary class Salt,Carboxylic acid,Carbamidine,Amine,Benzene,Ester,Protease,Ser/Thr Protease, name is 2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt, and the molecular formula is C17H19N3O7S, Synthetic Route of 71079-09-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Fritsche, Hans published the artcileReduction of organic compounds of pentavalent phosphorus to phosphines. III. Preparation of primary and secondary phosphines with silanes, Safety of Difluorodiphenylsilane, the publication is Chemische Berichte (1965), 98(5), 1681-7, database is CAplus.

cf. CA 62, 10457d. Phosphonate esters and phosphinic acids and their esters or chlorides, as well as di- and monohalophosphines were reduced with organic silanes or Cl₃SiH (I) to primary and secondary phosphines, resp. BuP(O)(OEt)₂ (II) (77.6 g.) and 147.2 g. Ph₂SiH₂ (III) heated 3 hrs. under N at 150-200¡ã yielded 27 g. BuPH₂ (IV), b. 60¡ã. II (19.4 g.) and 43 g. methylpolysiloxane (V) heated with stirring 3 hrs. under N at 200¡ã and then 2 hrs. at 275¡ã gave 8 g. IV. All runs were performed under N. PhP(O)(OEt)₂ (21.4 g.) and 36.8 g. III heated 2 hrs. at 200¡ã gave 9.6 g. PhPH₂ (VI), b. 130-40¡ã. PhPCl₂ (35.8 g.) and 36.8 g. III gave similarly 18 g. VI. PhPCl₂ (35.8 g.), 30 g. I, and 22 g. Et₃N in 250 cc. C₆H₆ refluxed 2 hrs. and treated with 150 cc. 2% aqueous NaOH gave 12 g. VI, b₁₄ 60¡ã. Bu₂P(O)OH (26.7 g.) and 41.4 g. III heated 4 hrs. at 200¡ã yielded 16.8 g. Bu₂PH, b₁₄ 68-70¡ã. Bu₂P(O)Cl (19.65 g.) and 27.6 g. III heated 3 hrs. at 250¡ã gave 13.9 g. Bu₂PH, b₁₄ 70¡ã. Bu₂P(O)Cl (19.65 g.), 30 g. I, and 22 g. Et₃N in 250 cc. C₆H₆ refluxed 2 hrs. yielded 9.2 g. Bu₂PH, b₁₄ 70¡ã. 1-Hydroxy-1-oxo-3,4-dimethyl-2-phospholene (21.8 g.) and 41.4 g. III heated 4 hrs. at 150-90¡ã yielded 13.8 g. 3,4-dimethyl-2-phospholene, b. 146-8¡ã. 1-Hydroxy-1-oxo-3-methyl-2-phospholene with III gave similarly 78% 3-methyl-2-phospholene, b. 80¡ã, and 1-hydroxy-1-oxo-2-phospholene with PhSiH₃ gave 73% 2-phospholene, b. 75¡ã. 10-Hydroxy-10-oxo-2,8-dimethylphenoxaphosphine (73 g.) and 84 g. III heated 3 hrs. at 250¡ã gave 54.2 g. 2,8-dimethylphenoxaphosphine, air-sensitive crystals, m. 56¡ã (under N). Ph₂P(O)(OMe) (34.8 g.) and 41.4 g. III heated 4 hrs. at 190¡ã yielded 16.8 g. Ph₂PH, b_0.35 105-15¡ã. Ph₂P(O)OH (22 g.) in 100 cc. dry C₆H₆ refluxed 2 hrs. with 40.6 g. I and treated with 100 cc. 20% aqueous NaOH yielded 7.2 g. Ph₂PH, b_0.3 110¡ã. Ph₂P(O)Cl (23.6 g.) and 27.6 g. III during 3 hrs. at 200-50¡ã yielded 16.5 g. Ph₂PH, b_0.07 107¡ã. Ph₂PCl (44 g.) and 18.4 g. III during 2 hrs. at 200¡ã gave 23 g. Ph₂PH, b₁₄ 165¡ã. Ph₂PCl (22 g.), 15 g. I, and 11 g. Et₃N in 80 cc. C₆H₆ refluxed 2 hrs. and treated with 80 cc. 30% aqueous NaOH gave 14 g. Ph₂PH, b₁₂ 155¡ã. 2,4,6-Me₃C₆H₂MgBr from 80 g. 2,4,6-Me₃C₆H₂Br and 9.6 g. Mg in tetrahydrofuran treated dropwise with 30.5 g. POCl₃ in tetrahydrofuran, and the precipitate refluxed 0.5 hr. with alc. NaOEt, treated with 20% aqueous NaOH, and again refluxed 0.5 hr. yielded 32 g. (2,4,6-Me₃C₆H₂)₂P(O)OH (VII), m. 210¡ã (EtOH). VII (13 g.) and 12 g. III heated 3 hrs. at 300¡ã yielded 4 g. (2,4,6-Me₃C₆H₂)₂PH (VIII), b_0.1 140-60¡ã, m. 74¡ã (EtOH). Chloride (18.6 g.) of VII and 6.3 g. PhSiH₃ heated 10 hrs. at 150¡ã, treated with 10 cc. EtOH, and refluxed 1 hr. gave 10.3 g. VIII. (p-Me₂NC₆H₄)₂P(O)OH (30.6 g.) and 28 g. III heated 2 hrs. at 200-50¡ã gave 15 g. (p-Me₂NC₆H₄)₂PH, b_0.05 220-5¡ã, m. 137¡ã.

Chemische Berichte published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Safety of Difluorodiphenylsilane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Ziwei published the artcileEstimating the deposition of polycyclic aromatic hydrocarbons in human airways: The role of particle size, Category: catalysis-chemistry, the publication is Atmospheric Pollution Research (2022), 13(7), 101461, database is CAplus.

Most previous studies used atm. concentrations of polycyclic aromatic hydrocarbons (PAHs) to estimate the risk of exposure via inhalation, but neglected the disparities in the effects of particle size. In this study, an extensive literature search retrieved data from 35 cities on atm. PAHs and particle size distributions, and a multiple-path particle dosimetry model was used to simulate the PAH deposition in human airways. The results revealed that the median concentration of total PAHs was 38 (range, 0.6-2074.2) ng/m³, while the median concentration of benzo(a)pyrene equivalent (B[a]Peq) was 11 ng/m³. Together with exposure to congener-specific PAHs, the median deposited concentrations of total PAHs or B[a]Peq were the highest in particulate matter (PM) with diameters of 1-2.5 ¦Ìm, followed by > 1 ¦Ìm and coarse PM, which can be explained by the general increase in proportions of high mol. weight PAHs with decreasing PM size. While the deposited PAHs were dominated by 3-5 rings PAHs, the deposited B[a]Peq was concentrated in 5-ring. Moreover, although differences in the contributions of the ring number between deposited and ambient PAHs were negligible, the contributions of fine PM were 11.9% and 9.5% greater for deposited PAHs and B[a]Peq, resp. These results indicate that the risk of exposure to PAHs attached to fine PM is underestimated previously.

Atmospheric Pollution Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C6H12Br2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Guo, Yanxia published the artcileEffect of Hydrogen-Consuming Compounds on In Vitro Ruminal Fermentation, Fatty Acids Profile, and Microbial Community in Water Buffalo, Quality Control of 6217-54-5, the publication is Current Microbiology (2022), 79(8), 220, database is CAplus and MEDLINE.

The present study aimed to investigate the effect of hydrogen-consuming compounds on ruminal methane (CH4) production, in vitro fermentation parameters, fatty acids profile, and microbial community in water buffalo. Different sodium nitrate to disodium fumarate ratios [2:1 (F), 1:1 (S), 1:2 (T)] were studied in vitro by batch culture technique in the presence of linoleic acid. Results revealed that the dominant bacterial communities were not affected with sodium nitrate and disodium fumarate, whereas CH4 production and Verrucomicrobia, Succiniclasticum, norank_f__Muribaculaceae, and Prevotellaceae_UCG-003 were reduced (P < 0.05). However, ruminal pH, unsaturated fatty acids/saturated fatty acids (UFA/SFA) and Campilobacterota, Selenomonas, Succinivibrio, Oribacterium, Christensenellaceae_R-7_group, Campylobacter, Shuttleworthia, Schwartzia, and Prevotellaceae_YAB2003_group were increased (P < 0.05). Total volatile fatty acids (TVFA) and Spirochaetae, Fibrobacterota, Verrucomicrobia, Fibrobacter, Treponema, and Prevotellaceae were decreased in F (P < 0.05), but cis-9, trans-11CLA, acetate/propionate and Proteobacteria, Campilobacterota, Selenomonas, Succinivibrio, and Campylobacter were increased in F (P < 0.05). The highly selected bacterial genera in F were Campylobacter and Succinivibrio. The disodium fumarate, enhanced (P < 0.05) the TVFA, propionate, total bacteria, Butyrivibrio proteoclasticus, and Atypical butyrivibrio. The concentrations of C18:3n3, C20:3n6, C21:0, C22:2n6, and C22:1n9, as well as the populations of total fungi, protozoa, methanogens, Butyrivibrio hungatei in T were higher (P < 0.05). The highly selected bacterial genera in T were Fibrobacter and Treponema. Conclusively, the addition of sodium nitrate and disodium fumarate can reduce the CH4 production and optimize ruminal fatty acid composition Furthermore, disodium fumarate can alleviate the adverse effect of sodium nitrate on the rumen fermentation

Current Microbiology published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Quality Control of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia