Catalysis-chemistry

Zahra, Urage published the artcileNew acetylphenol-based acyl thioureas broaden the scope of drug candidates for urease inhibition: synthesis, in vitro screening and in silico analysis, HPLC of Formula: 118-90-1, the publication is International Journal of Biological Macromolecules (2022), 157-167, database is CAplus and MEDLINE.

In the present research, developed a new series of acetylphenol-based acyl thioureas I [R = t-Bu, 2-MeC₆H₄, 4-ClC₆H₄, etc.] that could potentially provide a new template for drug candidates to inhibit urease enzyme. Newly synthesized compounds I were evaluated for urease inhibitory strength using thiourea as a pos. control. In vitro inhibitory results revealed that all the tested compounds were significantly potent than the standard drug. The most active lead compound I [R =3-ClC₆H₄] competitively inhibited the enzyme and displayed an IC₅₀ value of 0.054 ¡À 0.002¦ÌM, a ?413-fold strong inhibitory potential than thiourea (IC₅₀ = 22.3 ¡À 0.031¦ÌM). Various insightful structure-activity relationships were developed showing the key structural requirements for potent inhibitory effects. Mol. docking anal. of compound I [R =3-ClC₆H₄] inside the active pocket of urease suggested several important interactions with amino acid residues such as ILE411, MET637, ARG439, GLN635, ALA636 and ALA440. Finally, pharmacokinetic properties suggested that the tested derivatives were safe to develop as low-mol.-weight drugs to treat ureolytic bacterial infections.

International Journal of Biological Macromolecules published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C9H12O, HPLC of Formula: 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Grinevich, I. A. published the artcileRadiation synthesis of ¦Á,¦Á-branched carboxylic acids, Recommanded Product: 2-Butylhexanoic acid, the publication is Trudy Instituta – Moskovskii Khimiko-Tekhnologicheskii Institut imeni D. I. Mendeleeva (1974), 21-4, database is CAplus.

Radiation-induced telomerization of C2H4 with AcOH at 25¡ã afforded mixtures containing PrCO2H, C5H11CO2H, BuCHMeCO2H, C7H15CO2H, and Bu2CHCO2H; analogous reaction with Me2CHCO2H afforded mixtures containing RCMe2CO2H (R = Et, Bu, C6H13, C8H17).

Trudy Instituta – Moskovskii Khimiko-Tekhnologicheskii Institut imeni D. I. Mendeleeva published new progress about 3115-28-4. 3115-28-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is 2-Butylhexanoic acid, and the molecular formula is C10H20O2, Recommanded Product: 2-Butylhexanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Song, Dongying published the artcileEffects of faba bean (Vicia faba L.) on fillet quality of Yellow River carp (Cyprinus carpio) via the oxidative stress response, Product Details of C22H32O2, the publication is Food Chemistry (2022), 132953, database is CAplus and MEDLINE.

In order to further explain the fillet texture improvement of Yellow River carp (Cyprinus carpio) fed with faba bean (Vicia faba L.), a three-month rearing trial was conducted to investigate fatty acid composition, antioxidant capacity, myofiber development, collagen deposition and transcriptome in white muscle of two farmed carp groups (One was fed only faba bean, the other was fed com. diet). As a strong oxidant, faba bean changed fatty acids composition in white muscle, especially DHA and EPA, up-regulated the levels of reactive oxygen species (ROS) and down-regulated major antioxidant enzyme activities in the hepatopancreas and white muscle. Through the anal. of transcriptome and subsequent verification anal., we speculated that the increase of ROS led to the decrease of myofiber diameter and collagen metabolism This study provides a theor. basis for further understanding the regulation of faba bean on fillet texture characteristic of Yellow River carp.

Food Chemistry published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C15H14N2, Product Details of C22H32O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Akin, Ummuhan published the artcileDielectric properties of coronene film deposited onto silicon substrate by spin coating for optoelectronic applications, Related Products of catalysis-chemistry, the publication is Silicon (2022), 14(5), 2201-2209, database is CAplus.

To determine the elec. modulus, dielec. properties, and ac conductivity of coronene semiconductor layer, the have produced Al/Coronene/n-Si structure by using the thermally evaporation and spin coating method. The variation of dielec. constant (¦Å’), dielec. imaginary part (¦Å”), tangent loss (tan¦Ä), elec. modulus (M‘ and M”), and AC elec. conductivity (¦Ò_ac) with voltage and frequency of Coronene semiconductor layer have been investigated in the frequency range of 1 kHz – 1 MHz and at the selected voltages (0.0-0.4 V with steps 0.02 V). It is found that the ¦Å’ and ¦Å” values decrease with increasing frequency while an increase is observed in tan¦Ä, ¦Ò_ac, and the real (M‘) and the imaginary (M”) of the elec. modulus. The ¦Å’, & ¦Å” tan¦Ä, ¦Ò_ac, M‘ and M” values have been determined as 6.53, 8.58, 1.31, 0.0477 S/cm, 0.0561 and 0.0477 for 1 kHz and 0.0046, 0.129, 2.78, 7.17 S/cm, 0.278, and 7.74 for 1 MHz at 0.0 V, resp.

Silicon published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Zhiyong published the artcileOPEN ACCESS sources and health risks of PM 2.5 -bound PAHs in a small city along with the “clean heating” policy, Recommanded Product: Coronene, the publication is Aerosol and Air Quality Research (2022), 22(7), 220162, database is CAplus.

Levels, composition, and sources of PM_2.5-bound polycyclic aromatic hydrocarbons (PAHs) vary significantly along with the “Clean Heating” (CH) policy in Beijing-Tianjin-Hebei (BTH) region, whereas the PAH characteristics with CH in small cities still remain unclear. A field observation was conducted in Baoding City, a small city within the BTH region, in winter of 2019 covering both the pre-heating season (PHS) and the heating season (HS). From the PHS to the HS, the mean concentrations for both PM_2.5 and ¡Æ18PAHs increased from 69.1 to 125.0 ¦Ìg m^-3 and from 8.09 to 26.2 ng m^-3 due to the heating activities. The far lower PAHs in this study than those of small cities before CH implementation indicated the CH effectiveness. Higher diagnostic ratios (DRs) of FA/(FA + PY), BaA/(BaA + CHR), and IP/(IP + BgP) in the HS were in agreement with the increased coal/biomass usage. Pos. matrix factorization (PMF) demonstrated that biomass/natural-gas burning (BNGB) contributed most to PAHs of 36.9% in the HS, the increased natural gas (NG) usage for heating should be responsible for this contribution due to the policies of biomass-burning prohibition and ¡äCoal to Gas¡ä. Coal combustion (CC) shares increased by 152% in the HS despite the ¡äCoal Banning¡ä project. Again, the medium-mol.-weight PAHs (MMW-PAHs) increased most by 400% in the HS, evidencing the increased impacts of fossil-fuel consumptions. As an indicator for carcinogenic risk, BaP increased from 0.937 in the PHS to 1.29 ng m^-3 in the HS. Furthermore, the incremental lifetime cancer risks (ILCR) and BaP equivalent concentrations (BaPeq) increased in the HS. The mean ILCR values of 1.15 x 10^-6 for adults in the HS exceeded the threshold of 1 x 10^-6 , while they were lower than 1 x 10^-6 for children in both the PHS and the HS, and adults in the PHS due to the CH pos. effects.

Aerosol and Air Quality Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Recommanded Product: Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liang, Yu-Feng published the artcileMetal-Free I₂-Catalyzed Highly Selective Dehydrogenative Coupling of Alcohols and Cyclohexenones, Name: 4-(Phenoxymethyl)benzoic acid, the publication is Chinese Journal of Chemistry (2018), 36(3), 233-240, database is CAplus.

The I₂ catalyzed highly selective oxidative condensation of cyclohexenones and alcs. for the synthesis of aryl alkyl ethers was described. DMSO was employed as the mild terminal oxidant. This novel methodol. offered a metal-free reaction condition, operational simplicity and broad substrate scope to afford valuable products from inexpensive reagents. Various meta-substituted aromatic ethers which were hardly synthesized from the reported methods requiring meta-substituted phenols were efficiently prepared by the present protocol.

Chinese Journal of Chemistry published new progress about 31719-76-3. 31719-76-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 4-(Phenoxymethyl)benzoic acid, and the molecular formula is C14H12O3, Name: 4-(Phenoxymethyl)benzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Muliang published the artcileDeoxygenative Deuteration of Carboxylic Acids with D₂O, Synthetic Route of 22693-41-0, the publication is Angewandte Chemie, International Edition (2019), 58(1), 312-316, database is CAplus and MEDLINE.

C1-Deuterated aryl and alkyl aldehydes such as 4-PhC₆H₄CDO and PhCH₂CH₂CDO were prepared chemoselectively with 58-96% deuterium incorporation by reduction of aromatic and aliphatic carboxylic acids using iridium photocatalysts, either Ph₃P or Ph₂OEt as an oxygen acceptor, 2,4,6-i-Pr₃C₆H₂SH as a hydrogen atom donor, and using D₂O as an inexpensive deuterium source. The method was used for the preparation of deuterated derivatives of pharmaceuticals and natural products containing aromatic carboxylic acid moieties. The method was also used for chemoselective reduction of aryl and alkyl carboxylic acids to the corresponding aldehydes using H₂O as a hydrogen atom source.

Angewandte Chemie, International Edition published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C8H11BO3, Synthetic Route of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhao, Guangkuan published the artcileChlorotrimethylsilane and Sodium Iodide: A Remarkable Metal-Free Association for the Desulfurization of Benzylic Dithioketals under Mild Conditions, Recommanded Product: Bis(4-fluorophenyl)methane, the publication is Advanced Synthesis & Catalysis (2018), 360(13), 2522-2536, database is CAplus.

A novel metal-free process allowing the reductive desulfurization of various benzylic dithioketals to afford arylmethanes and benzylester derivatives with good to excellent yields was reported. At room temperature, this mild reduction process required only the use of TMSCl and NaI in CH₂Cl₂ and tolerated a large variety of functional groups.

Advanced Synthesis & Catalysis published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C18H24N6O6S4, Recommanded Product: Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lan, Yingdong published the artcilePhosphorus ligand-free Suzuki-Miyaura reactions in the presence of ABTS at room temperature in water, HPLC of Formula: 613-33-2, the publication is Canadian Journal of Chemistry (2021), 99(5), 491-495, database is CAplus.

A catalytic system for a phosphorus ligand-free Suzuki-Miyaura reaction in water at room temperature was disclosed. Ammonium 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonate) (ABTS) was an efficient promoter and acted both as a ligand and as a surfactant for the synthesis of biaryl compounds via the Suzuki-Miyaura reaction in water. The targeted biaryl architectures were achieved under mild conditions with high efficiency and good functional group tolerance.

Canadian Journal of Chemistry published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, HPLC of Formula: 613-33-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ouyang, Hao published the artcileSynthesis and Characterization of Dinuclear Salan Rare-Earth Metal Complexes and Their Application in the Homo- and Copolymerization of Cyclic Esters, Name: N1,N2-Dibenzylethane-1,2-diamine, the publication is Inorganic Chemistry (2018), 57(15), 9028-9038, database is CAplus and MEDLINE.

Four rare-earth-metal aryloxo complexes stabilized by a tetradentate Salan ligand were prepared, and their catalytic properties for the (co)polymerization of lactides and ¦Å-caprolactone were elucidated. The proton-exchange reactions of (C₅H₅)₃Ln(THF) with the Salan ligand N,N’-(CH₂Ph)₂-N,N’-[CH₂(2-OH-C₆H₂-Me₂-3,5)]₂ (LH₂) in a 1:1 molar ratio, and subsequently with 1 equiv of p-methylphenol, gave the rare-earth-metal aryloxides [LLn(OC₆H₄-4-CH₃)(THF)_n]₂ [n = 0 and Ln = Y (1), Sm (2), and Nd (3); n = 1 and Ln = La (4)] in good isolated yields. These complexes were fully characterized by elemental anal., IR, and NMR spectroscopy (for complexes 1 and 4). Solid-state structures of complexes 1-4 were confirmed by single-crystal X-ray diffraction anal. Complexes 1-4 have dinuclear solid-state structures, with a Ln₂O₂ core bridging the Salan ligands. The coordination geometry around each of the metals is a slightly distorted octahedron in complexes 1-3, whereas it is a capped trigonal prism in complex 4. It was found that complexes 1-4 can initiate efficiently the homopolymerization of L-lactide (L-LA) and rac-lactide (rac-LA) at 30 ¡ãC in THF. The increasing activity of these complexes is in agreement with increasing ionic radii. A kinetic study revealed that seven-coordinated lanthanum complex 4 is more active for rac-LA polymerization compared with L-LA. A further study revealed that complex 4 was also an efficient initiator for the random copolymerization of L-LA and ¦Å-caprolactone with the simultaneous addition of these two monomers, and the T_g values of the copolymers obtained increase linearly from -30.2 to +38.3 ¡ãC with an increase of the percentage of LA units. A mechanism study revealed that transesterification plays a crucial role in the formation of a random copolymer.

Inorganic Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Name: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia