Catalysis-chemistry

Takacs, James M. published the artcileCatalytic Iron-Mediated Enediene Carbocyclizations: Investigations into the Stereoselective Formation of Bicyclic Ring Systems, Name: Allyldiphenylphosphine oxide, the publication is Journal of Organic Chemistry (1995), 60(11), 3473-86, database is CAplus.

Trienes in which the requisite 1,3-diene and allylic ether moieties are appended to a pre-existing ring system afford bicyclic ring systems upon iron-catalyzed cyclization. The efficiency and stereoselectivity of the cyclization are dramatically influenced by the nature of the ring system to which the diene and alkene subunits are appended. Certain bicyclic ring systems are formed in good yield; most notably, substrates bearing a basic nitrogen are well-tolerated and certain indolizidine and quinolizidine ring systems are accessible using this methodol. The efficiency and stereoselectivity of the cyclization is also markedly dependent on the ligand used to modify the iron catalyst, and in this regard, a bisoxazoline-modified iron catalyst system is generally superior to what was the standard bipyridine-modified catalyst. In the course of these studies a difference spin polarization transfer (DSPT) experiment proved very useful for the stereochem. anal. of compounds that exhibit very crowded high field NMR spectra.

Journal of Organic Chemistry published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C10H10O4, Name: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Beckh, Karlheinz published the artcileHepatic and pancreatic metabolism and biliary excretion of the protease inhibitor camostat mesilate, Computed Properties of 71079-09-9, the publication is International Journal of Pancreatology (1991), 10(3-4), 197-205, database is CAplus and MEDLINE.

The hepatic metabolism and biliary and pancreatic excretion of the serine protease inhibitor camostat mesilate and its metabolites FOY-251 and GBA were studied in rats in vivo and in situ liver-perfusion experiments After oral feeding (100 mg/kg) and i.v. infusion (5 mg/kg.h) of camostat mesilate, the original compound and both metabolites appeared in bile, but could not be detected in pancreatic juice. In plasma, only FOY-251 and GBA were detected. In the perfused rat liver, camostat mesilate (10 ¦ÌM) was eliminated by 33.8% and its molar rate of degradation to FOY-251 was 25.1%. During the study period about 0.1% of camostat mesilate and FOY-251 appeared in bile. The liver perfusion of FOY-251 or GBA revealed very low hepatic extraction rates of 10.3 and 2.4%, resp. In conclusion, the low hepatic extraction rate of camostat mesilate and its metabolites leads to high concentrations of the active metabolite FOY-251 in plasma. Camostat mesilate and its metabolites are effectively excreted into bile, but not in rat pancreatic juice.

International Journal of Pancreatology published new progress about 71079-09-9. 71079-09-9 belongs to catalysis-chemistry, auxiliary class Salt,Carboxylic acid,Carbamidine,Amine,Benzene,Ester,Protease,Ser/Thr Protease, name is 2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt, and the molecular formula is C17H19N3O7S, Computed Properties of 71079-09-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Han, Jianlei published the artcileDecarboxylative bromination of cinnamic acids by 2-iodoxybenzoic acid with tetrabutylammonium bromide, Recommanded Product: (E)-3-(3-Nitrophenyl)acrylic acid, the publication is Journal of Chemical Research (2012), 36(5), 247-248, database is CAplus.

The decarboxylative bromination of cinnamic acids using the hypervalent iodine reagent 2-iodoxybenzoic acid with tetrabutylammonium bromide was described, providing good to excellent yields of bromostyrenes.

Journal of Chemical Research published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C9H7NO4, Recommanded Product: (E)-3-(3-Nitrophenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yao, Zishuo published the artcileCompositional and structural features of the extracts from Shenfu coal, Formula: C10H20O2, the publication is Wuhan Keji Daxue Xuebao (2009), 32(6), 631-637, database is CAplus.

Shenfu coal was sequentially extracted with benzene, methanol, acetone, acetone/CS₂ and tetrahydro furan, and each extract was subject to ruthenium ion-catalyzed oxidation After being esterified with diazomethane, the products were analyzed with gas chromatog.-mass spectrometry. The differences in composition and structure between the extracts are inferred by comparing the differences between the products. The results show that the main components in the products from Shenfu coal extracts are Me alkanoates and di-Me alkanedioates, implying that Shenfu coal extracts contain large amount of alkylarenes and ¦Á, ¦Ø-diarylalkanes. Carbon number of the Me alkanoates and di-Me alkanedioates increases with increasing solvent polarity, suggesting the long-chain alkylarenes and ¦Á, ¦Ø-diarylalkanes in Shenfu coal are soluble in solvents with stronger polarity. Nineteen kinds of Me steranoates, Me terpanoates and Me hopanoates were detected, indicating that the extracts contain steryl, terpyl and hopylarom. moieties.

Wuhan Keji Daxue Xuebao published new progress about 3115-28-4. 3115-28-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is 2-Butylhexanoic acid, and the molecular formula is C9H4F6O, Formula: C10H20O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yu, Jiahui published the artcileEvaluation of total, sn-2 fatty acid, and triacylglycerol composition in commercial infant formulas on the Chinese market: A comparative study of preterm and term formulas, Category: catalysis-chemistry, the publication is Food Chemistry (2022), 132477, database is CAplus and MEDLINE.

Preterm infants with physiol. immaturity require higher lipid provision than term infants. This study compared the lipid composition, including total, sn-2 fatty acid, and triacylglycerol (TAG) compositions in 14 preterm formulas and 25 term formulas in the Chinese market, in 2020-2021. Preterm formula had higher medium-chain fatty acid (MCFA) and comparable C22:6n-3 (DHA) contents than term formula. Notably, significantly lower C16:0 and C18:0 (p < 0.001) were distributed on the sn-2 position in preterm formula. Two hundred and thirteen kinds of TAG mol. species were identified using UPLC-Q-TOF-MS. In preterm formula, significantly higher Ca-Ca-Cy and Ca-Ca-Ca (p < 0.001) existed. These clear distinctions showed the challenge of the progress in preterm formula, such as DHA status, MCFA pattern, and TAG esterified with palmitic acid on the sn-2 position.

Food Chemistry published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C9H8BNO2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Xu-Dong published the artcileSynthesis, molecular docking and biological evaluation of 3-arylfuran-2(5H)-ones as anti-gastric ulcer agent, Name: 2-(3-(Benzyloxy)phenyl)acetic acid, the publication is Bioorganic & Medicinal Chemistry (2015), 23(15), 4860-4865, database is CAplus and MEDLINE.

3-Arylfuran-2(5H)-one derivatives show good antibacterial activity and were determined as tyrosyl-tRNA synthetase (TyrRS) inhibitors. In a systematic medicinal chem. exploration, we demonstrated chem. opportunities to treat infections caused by Helicobacter pylori. Twenty 3-arylfuran-2(5H)-ones were synthesized and evaluated for anti-H. pylori, antioxidant and anti-urease activities which are closely interconnected with H. pylori infection. The results displayed that some of the compounds show excellent antioxidant activity, and good anti-H. pylori and urease inhibitory activities. Out of these compounds, 3-(3-methylphenyl)furan-2(5H)-one (I) showed the most potent antioxidant activity (IC₅₀ = 8.2 ¦ÌM) and good anti-H. pylori activity (MIC₅₀ = 2.6 ¦Ìg/mL), and it can be used as a good candidate for discovering novel anti-gastric ulcer agent.

Bioorganic & Medicinal Chemistry published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C8H11BO2, Name: 2-(3-(Benzyloxy)phenyl)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Jiamei published the artcileEnabling chemical protein (semi)synthesis via reducible solubilizing tags (RSTs), Application In Synthesis of 71989-31-6, the publication is Chemical Science (2022), 13(5), 1367-1374, database is CAplus and MEDLINE.

Chem. synthesis of proteins with poor solubility presents a challenging task. The existing solubilizing tag strategies are not suitable for the expressed protein segment. To address this issue, we report herein that solubilizing tags could be introduced at the side chain of the peptide and C-terminal peptide salicylaldehyde esters via a disulfide linker. Such reducible solubilizing tags (RSTs) are compatible with peptide salicylaldehyde ester-mediated Ser/Thr ligation and Cys/Pen ligation for purifying and ligating peptides with poor solubility This strategy features operational simplicity and readily accessible materials. Both the protein 2B4 cytoplasmic tail and FCER1G protein have been successfully synthesized via this strategy. Of particular note, the RST strategy could be used for solubilizing the expressed protein segment for protein semi-synthesis of the HMGB1 protein.

Chemical Science published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Application In Synthesis of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Cui, Wen-hui published the artcileSynthesis of 1,1′-[1,4-phenylenebis(methylene)]bis[1H-benzimidazole] isomers under microwave irradiation conditions, SDS of cas: 5411-14-3, the publication is Huaxue Shiji (2007), 29(8), 487-489, database is CAplus.

The title compounds were synthesized under microwave-irradiation conditions using benzenediamine and 2,2′-[phenylenebis(oxy)]bis[acetic acid] isomers as starting materials in the presence of polyphosphoric acid (PPA) and 4 mol/L hydrochloric acid as catalyst. The power of microwave irradiation applied was 650-850 W. The reaction time was 10-15 min. Product structures were confirmed by IR, ¹HNMR, ¹³CNMR, MS and elementary anal.

Huaxue Shiji published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, SDS of cas: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Xicun published the artcilePhase transfer catalyzed synthesis of N,N-diaryl-1,2-phenylene dioxydiacetamides, Safety of 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Synthetic Communications (1996), 26(14), 2765-2773, database is CAplus.

The reaction of 2,2′-[1,2-phenylenebis(oxy)]bis[acetic chloride] with arylamines gave 2,2′-[1,2-phenylenebis(oxy)]bis[N-arylacetamides] I (R = Ph, thiazolyl, naphthalenyl, etc.). The reactions were carried out under liquid-liquid phase transfer conditions, using polyethylene glycol-400 as a catalyst.

Synthetic Communications published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C18H10F3NO3S2, Safety of 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hu, Yuehua published the artcileRole of macromolecules in kaolinite flotation, HPLC of Formula: 2016-56-0, the publication is Minerals Engineering (2004), 17(9-10), 1017-1022, database is CAplus.

Flotation tests show that the floatability of kaolinite is much better in an acidic than in an alk. medium containing cationic collectors. The (001) basal planes of kaolinite are found to adsorb cationic collectors favorably, which render the surface hydrophobic. The (001) planes interact with macromols. carrying groups containing -O-, -N-, and/or -F- of high electronegativity, and the resultant flocculation minimizes the exposure of hydrophilic (001) planes. As a result, the cationic flotation of kaolinite is enhanced by the addition of these types of macromols. The zeta potential measurement and macromol. adsorption study indicate that the adsorption of anionic PAM on kaolinite is dominated mainly by hydrogen bonding interactions.

Minerals Engineering published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, HPLC of Formula: 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia