Catalysis-chemistry

Jang, Hyun-June published the artcileRemote Floating-Gate Field-Effect Transistor with 2-Dimensional Reduced Graphene Oxide Sensing Layer for Reliable Detection of SARS-CoV-2 Spike Proteins, HPLC of Formula: 13822-56-5, the publication is ACS Applied Materials & Interfaces (2022), 14(21), 24187-24196, database is CAplus and MEDLINE.

Despite intensive research of nanomaterials-based field-effect transistors (FETs) as a rapid diagnostic tool, it remains to be seen for FET sensors to be used for clin. applications due to a lack of stability, reliability, reproducibility, and scalability for mass production Herein, we propose a remote floating-gate (RFG) FET configuration to eliminate device-to-device variations of two-dimensional reduced graphene oxide (rGO) sensing surfaces and most of the instability at the solution interface. Also, critical mechanistic factors behind the electrochem. instability of rGO such as severe drift and hysteresis were identified through extensive studies on rGO-solution interfaces varied by rGO thickness, coverage, and reduction temperature rGO surfaces in our RFGFET structure displayed a Nernstian response of 54 mV/pH (from pH 2 to 11) with a 90% yield (9 samples out of total 10), coefficient of variation (CV) < 3%, and a low drift rate of 2%, all of which were calculated from the absolute measurement values. As proof-of-concept, we demonstrated highly reliable, reproducible, and label-free detection of spike proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a saliva-relevant media with concentrations ranging from 500 fg/mL to 5¦Ìg/mL, with an R² value of 0.984 and CV < 3%, and a guaranteed limit of detection at a few pg/mL. Taken together, this new platform may have an immense effect on positioning FET bioelectronics in a clin. setting for detecting SARS-CoV-2.

ACS Applied Materials & Interfaces published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C6H17NO3Si, HPLC of Formula: 13822-56-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ikeda, Shuhei published the artcileDesign and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety, Formula: C7H9NO4, the publication is Journal of Medicinal Chemistry (2021), 64(15), 11014-11044, database is CAplus and MEDLINE.

The therapeutic potential of monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases has attracted attention worldwide. However, the availability of reversible-type inhibitor is still limited to clarify the pharmacol. effect. Herein, we report the discovery of novel spiro chem. series as potent and reversible MAGL inhibitors with a different binding mode to MAGL using Arg57 and His121. Starting from hit compound 1 and its co-crystal structure with MAGL, structure-based drug discovery (SBDD) approach enabled us to generate various spiro scaffolds like 2a (azetidine-lactam), 2b (cyclobutane-lactam), and 2d (cyclobutane-carbamate) as novel bioisosteres of 3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl moiety in 1 with higher lipophilic ligand efficiency (LLE). Optimization of the left hand side afforded 4f (I) as a promising reversible MAGL inhibitor, which showed potent in vitro MAGL inhibitory activity (IC₅₀ 6.2 nM), good oral absorption, blood-brain barrier penetration, and significant pharmacodynamic changes (2-arachidonoylglycerol increase and arachidonic acid decrease) at 0.3-10 mg/kg, po. in mice.

Journal of Medicinal Chemistry published new progress about 2135785-62-3. 2135785-62-3 belongs to catalysis-chemistry, auxiliary class Oxazolidines, name is cis-6-Oxo-7-oxa-5-azaspiro[3.4]octane-2-carboxylic acid, and the molecular formula is C7H9NO4, Formula: C7H9NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hojo, Yasuji published the artcileSpecific ability of sulfur-ligands to remove mercury-203-labeled organomercury from hemoglobin in comparison with nitrogen-ligands, SDS of cas: 10517-44-9, the publication is Radioisotopes (1975), 24(10), 684-8, database is CAplus.

Organomercurials (chloromerodrin [62-37-3], methylmercuric chloride [115-09-3], ethylmercuric chloride [107-27-7] and phenylmercuric acetate [62-38-4]) bound to sulfhydryl groups of Hb were removed by chelating agents including sulfur-ligands (penicillamine [52-67-5], glutathione [70-18-8]) and nitrogen-ligands (EDTA [60-00-4], glycine [56-40-6], polyethylenediamines). The effect of sulfur-ligands was higher and more sp. than that of nitrogen-ligands. A linear correlation was observed between the extent of organomercurial removal and the stability constant (log K1) of the organomercury complex with sulfur- and nitrogen-ligands. At a fixed value of log K1, sulfur-ligands were more effective than nitrogen-ligands. With the exception of chloromeredin, a linear correlation was also observed between the average percentage of removal and the Taft’s polar substituent constant for the organic moiety of the metal. The average removal percentage by sulfur-ligands increased in the order: ethylmercury > methylmercury > phenylmercury, whereas that by nitrogen-ligands was similar.

Radioisotopes published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, SDS of cas: 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nicolaou, K. C. published the artcileNew synthetic technology for the construction of N-containing quinones and derivatives thereof: total synthesis of epoxyquinomycin B, COA of Formula: C15H15OP, the publication is Angewandte Chemie, International Edition (2001), 40(1), 207-210, database is CAplus and MEDLINE.

N-substituted p-quinones and o-azaquinones are prepared regioselectively in a one-step tandem double oxidation of anilides by Dess-Martin periodinane. This process is applied to the short and efficient total synthesis of epoxyquinomycin B. The intermol. and intramol. Diels-Alder reactions of N-containing quinones are demonstrated. The o-azaquinones are shown to participate in inverse electron demand Diels-Alder reactions with electron-rich olefins.

Angewandte Chemie, International Edition published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, COA of Formula: C15H15OP.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nicolaou, K. C. published the artcileIodine(V) Reagents in Organic Synthesis. Part 2. Access to Complex Molecular Architectures via Dess-Martin Periodinane-Generated o-Imidoquinones, Application of Allyldiphenylphosphine oxide, the publication is Journal of the American Chemical Society (2002), 124(10), 2221-2232, database is CAplus and MEDLINE.

2-Amido-1,4-benzoquinones can be prepared from 4-substituted anilides lacking pendant alkenes by treatment with DMP and water followed by careful workup under neutral conditions. The oxidative preparation of 2-amido-1,4-benzoquinones has been used in the synthesis of the natural products epoxyquinomycin B and BE-10988 and in the preparation of a macrocyclic amide with a tetrahydronaphthoquinone moiety. Ortho-substituted N-aryl acetamides lacking pendant alkenes undergo oxidation with DMP and water to give o-imidoquinones which are stable for several months when stored under argon at low temperature in the absence of light. O-imidoquinones undergo intermol. Diels-Alder cycloadditions with vinyl ethers and sulfides to give phenoxazines. The treatment of anilides containing pendant alkenes with Dess-Martin periodinane (DMP) in the presence of water gives oxazine-containing polycyclic compounds by stereoselective oxidation to o-imidoquinones followed by stereoselective intramol. Diels-Alder cycloaddition The isobutyrylaminophenylheptadiene (E)-Me₂CHCONH-4-C₆H₄CH₂CH₂CH₂CH:CHCH:CH₂ undergoes stereoselective oxidative cyclization upon treatment with DMP in methylene chloride to give ketoamidohydroxyphenalenone I in 28% yield and an amidoquinone which undergoes thermal Diels-Alder cyclization to give hexahydrobenzindene II in 25% yield; I and II are related to the natural products pseudopterosin A and elisabethin A, resp. The ketohydroxyamide moiety in I undergoes cyclization, condensation, and cyclocondensation reactions with aromatic amines, aromatic diamines, amino acid esters, and amino alcs. to give spirocycles, fused diazaheterocycles, and phenalene derivatives

Journal of the American Chemical Society published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Application of Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tomoda, Susumu published the artcileThe effect of surfactant properties on lapping behavior of materials, Computed Properties of 2016-56-0, the publication is International Journal of the Japan Society for Precision Engineering (1997), 31(1), 21-25, database is CAplus.

This paper describes the effect of the polarity of the surfactant on lapping behavior such as stock removal and the amount of minute powders adhered to or embedded in the lapping surface which arise out of the lapping plate and the workpiece. Brass, steel, glass and other materials were lapped by surfactants with different polarity and varied lapping plates. Most anion surfactants appear to be better mediums than cation or nonion surfactants for preventing any adhesion of the minute powders and increasing stock removal. When the silver surface is lapped by using fine aluminum oxide abrasive grains in n-dodecyltrimethyl-ammonium chloride solution (cation) on the glass lapping plate, it is highly resistant to wear, but the rigid glass lapping plate wears out.

International Journal of the Japan Society for Precision Engineering published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C5H10Cl3O3P, Computed Properties of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tsunekawa, Masami published the artcileReactions of collector ions and ions from salt-type minerals, Recommanded Product: Dodecylamineacetate, the publication is Shigen to Sozai (1990), 106(1), 47-51, database is CAplus.

Precipitation reactions between 6 surfactants and several cations or anions of salt-type minerals were studied by nephelometry. Solubility products were determined for precipitates of metal ions with Na dodecylsulfate(SDS), n-oleoylsarcosine(OLSA) and Na oleate(NaOl), whereas the mini. concentrations of metal ions or anions to form precipitates with Na octadecylsulfosuccinamate(SOSS), N-tallow-1,3-diaminopropanedioleate(TDO) and dodecylammonium acetate (DAA) were measured. SOSS, OLSA, TDO and SDS preferred to react with La³⁺, Ce³⁺ and Ba²⁺ rather than CA²⁺ and Mn²⁺. TDO and DAA formed precipitates with WO₄^2-, SO₄^2-, H₂PO₄^– and HCO₃^– but not with F^–. Possible selective flotation and adsorption mechanism were discussed.

Shigen to Sozai published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C21H37BO, Recommanded Product: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Guvvala, Vinodh published the artcileDevelopment of a Novel and Scalable Process for the Synthesis of a Key Cangrelor Intermediate, Related Products of catalysis-chemistry, the publication is Organic Preparations and Procedures International (2019), 51(6), 530-536, database is CAplus.

An alternative synthetic route to the cangrelor key synthon, I, was developed with >99.5% purity without addnl. purifications. This improved method involves five steps starting from readily and cheaply available xanthine. Our process is scalable, cost effective, with simplified reaction workup, and avoids the use of costly metal catalysts or chromatog. Of note, this may be a com. viable large scale synthesis compared to previous methods.

Organic Preparations and Procedures International published new progress about 6950-53-4. 6950-53-4 belongs to catalysis-chemistry, auxiliary class Salt,sulfides,Amine,Aliphatic hydrocarbon chain, name is 2-(Methylthio)ethanamine hydrochloride, and the molecular formula is C3H10ClNS, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chockalingam, Evvie published the artcileStudies on biodegradation of organic flotation collectors using Bacillus polymyxa, COA of Formula: C14H31NO2, the publication is Process Metallurgy (2001), 433-442, database is CAplus.

Biodegradation of organic flotation collectors namely sodium isopropylxanthate, dodecylammonium acetate, and sodium oleate in solution was studied using Bacillus polymyxa. The biodegradation was assessed under different conditions namely during growth, in the presence of the cells, metabolite or an active culture. Xanthate biodegradation was found to be better in the presence of an active culture or metabolite while the biodegradation of dodecylammonium acetate was more efficient during bacterial growth. The efficacy of biodegradation of sodium oleate was the highest using an active culture. The growth of the organism could be successfully achieved in the presence of the organic collectors. The surface chem. changes brought about by the interaction between the minerals namely galena, quartz, and calcite, collector, metabolite or cells served as indicators of the biodegradation process. The biol. stripping of the adsorbed collector reagents from mineral surfaces was also confirmed by FTIR spectroscopy.

Process Metallurgy published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, COA of Formula: C14H31NO2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chockalingam, Evvie published the artcileStudies on biodegradation of organic flotation collectors using Bacillus polymyxa, Recommanded Product: Dodecylamineacetate, the publication is Hydrometallurgy (2003), 71(1-2), 249-256, database is CAplus.

Biodegradation of organic flotation collectors, namely sodium isopropylxanthate, dodecylammonium acetate and sodium oleate in solution, was studied by using Bacillus polymyxa. The biodegradation has been assessed under different conditions, namely during growth, in the presence of the cells, metabolite or an active culture. Xanthate biodegradation was better in the presence of an active culture or metabolite, while the biodegradation of dodecylammonium acetate was more efficient during bacterial growth. The efficacy of biodegradation of sodium oleate was the highest by using an active culture. The growth of the organism can be successfully achieved in the presence of the organic collectors. The surface chem. changes brought about by the interaction between the minerals, namely galena, quartz or calcite and collector, metabolite or cells served as indicators of the biodegradation process. The biol. stripping of the adsorbed collector reagents from mineral surfaces was also confirmed by FTIR spectroscopy.

Hydrometallurgy published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Recommanded Product: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia