Tag: M.W=100-150

Zhang, Zeshuai published the artcileSelective N-Monovinylation of Primary Aromatic Amides Using Calcium Carbide as an Alkyne Source, Quality Control of 118-90-1, the publication is ChemistrySelect (2022), 7(26), e202201463, database is CAplus.

An efficient method for the selective N-monovinylation of primary aromatic amides using calcium carbide as an alkyne source was described. A series of N-vinylbenzamides (enamides) RC(O)NHCH=CH₂ [R = Ph, 2-MeC₆H₄, 4-ClMeC₆H₄, etc.] were readily synthesized by this strategy. The salient features for this protocol were the use of inexpensive, easy-to-handle solid alkyne source, high chemoselectivity, transition metal catalyst-free, good functional group tolerance, and simple work-up procedures. These reactions was also be extended to the gram-scale level.

ChemistrySelect published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C18H23OP, Quality Control of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Eberl, H. Christian published the artcileChemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells, Formula: C3H8N2S, the publication is Scientific Reports (2019), 9(1), 1-14, database is CAplus and MEDLINE.

Kinobeads are a set of promiscuous kinase inhibitors immobilized on sepharose beads for the comprehensive enrichment of endogenously expressed protein kinases from cell lines and tissues. These beads enable chemoproteomics profiling of kinase inhibitors of interest in dose-dependent competition studies in combination with quant. mass spectrometry. We present improved bead matrixes that capture more than 350 protein kinases and 15 lipid kinases from human cell lysates, resp. A multiplexing strategy is suggested that enables determination of apparent dissociation constants in a single mass spectrometry experiment Miniaturization of the procedure enabled determining the target selectivity of the clin. BCR-ABL inhibitor dasatinib in peripheral blood mononuclear cell (PBMC) lysates from individual donors. Profiling of a set of Jak kinase inhibitors revealed kinase off-targets from nearly all kinase families underpinning the need to profile kinase inhibitors against the kinome. Potently bound off-targets of clin. inhibitors suggest polypharmacol., e.g. through MRCK alpha and beta, which bind to decernotinib with nanomolar affinity.

Scientific Reports published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Formula: C3H8N2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Reynolds, D. J. published the artcileCalculation of some nitrogen-15 and carbon-13 nuclear shielding parameters for some ureas and thioureas, Name: 1,1-Dimethylthiourea, the publication is Journal of Molecular Structure: THEOCHEM (1982), 7(3-4), 379-82, database is CAplus.

MO calculations using CNDO/S parameters are employed to determine bond-orders, charge-densities and the shielding of the ¹⁵N and ¹³C nuclei of a series of ureas and thioureas. For the sterically uncrowded mols. a linear relationship is noticed between the ¹⁵N chem. shifts and C-N bond-orders. When steric crowding occurs this simple relationship is no longer applicable.

Journal of Molecular Structure: THEOCHEM published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Name: 1,1-Dimethylthiourea.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rau, Johannes H. published the artcileReactive fibers, Part III. Reactions of reactive fibers based on cyanuric cellulose with low-molecular-weight compounds, Computed Properties of 6972-05-0, the publication is Melliand Textilberichte (1979), 60(3), 258-63, database is CAplus.

Treatment of cotton fabrics with compounds containing various functional groups at 30-80¡ã in aqueous solutions at pH 3-9 showed that compounds containing primary and secondary amino groups, compounds containing phenolic OH groups, and thiourea and its derivatives were fixed on the fibers. Most compounds were sulfo acids or contained S in another form so bonding to the fiber could be measured by determination of S. The amount of compound bonded to the fibers fell between 0.3-9.7%; the yield, based on the amount of Cl contained in the reactive fiber, lay between 2.8 and 74%.

Melliand Textilberichte published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Computed Properties of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wu, Zhe published the artcileGram-scale synthesis of carboxylic acids via catalytic acceptorless dehydrogenative coupling of alcohols and hydroxides at an ultralow Ru loading, Synthetic Route of 118-90-1, the publication is Applied Catalysis, A: General (2022), 118443, database is CAplus.

Acceptorless dehydrogenative coupling (ADC) of alcs. and water/hydroxides is an emergent and graceful approach to produce carboxylic acids. Therefore, it is of high demand to develop active and practical catalysts/catalytic systems for this attractive transformation. Herein, the design and fabrication of a series of cyclometallated N-heterocyclic carbene-Ru (NHC-Ru) complexes via ligand tuning of [Ru-1], the superior complex in the previous work. Gratifyingly, gram-scale synthesis of carboxylic acids was efficiently enabled at an ultralow Ru loading (62.5 ppm) in open air. Moreover, effects of distinct ancillary NHC ligands and other parameters on this catalytic process were thoroughly studied, while further systematic studies were carried out to provide rationales for the activity trend of [Ru-1]-[Ru-7]. Finally, determination of quant. green metrics illustrated that the present work exhibited superiority over representative literature reports. Hopefully, this study could provide valuable input for researchers who are engaging in metal-catalyzed ADC reactions.

Applied Catalysis, A: General published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C2H2N4O2, Synthetic Route of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ikeda, Osamu published the artcileAdsorption effects of highly polarizable organic compounds on electrode kinetics, Name: 1,1-Dimethylthiourea, the publication is Bulletin of the Chemical Society of Japan (1984), 57(12), 3363-7, database is CAplus.

Adsorption effects of urea; 1,1-dimethylurea; tetramethylurea; thiourea; 1,1-dimethylthiourea; and tetramethylthiourea on electrode kinetics were studied by using the electrode reactions of Zn²⁺/Zn(Hg) and Eu³⁺/Eu²⁺. The standard rate constant for Zn²⁺/Zn(Hg) is controlled by the inner-layer permittivity. The effect of this permittivity is explained in terms of the solvent reorganization energy. The effect of the adsorbates on the electrode kinetics of Eu³⁺/Eu²⁺ cannot be explained in terms of the inner layer permittivity. These 2 results suggest different locations for the formation of the activated complex: inside the adsorption layer for Zn²⁺ and just outside the layer for Eu³⁺.

Bulletin of the Chemical Society of Japan published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Name: 1,1-Dimethylthiourea.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jacquemin, Denis published the artcileAb initio investigation of the n ¡ú ¦Ð transitions in thiocarbonyl dyes, Quality Control of 6972-05-0, the publication is Journal of Physical Chemistry A (2006), 110(29), 9145-9152, database is CAplus and MEDLINE.

The n ¡ú ¦Ð* transitions in more than 100 thiocarbonyl dyes have been calculated with an ab initio procedure relying on the combination of time-dependent d. functional theory for evaluating excited states and the polarizable continuum model for modeling the bulk solvent effects on both the geometrical and electronic structures. Two hybrid functionals (B3LYP and PBE0) and several basis sets, some including f polarization functions, have been used. B3LYP provides the most accurate raw estimates, but once simple linear regression is performed, both functionals give similar results with a small advantage for PBE0. By use of the latter, the mean absolute deviation with respect to experiment is limited to 0.06 eV whereas less than 20% of the estimates differ from absorption data by more than 0.10 eV. To assess the validity limits of our model, compounds containing multiple C:S chromophores have also been considered.

Journal of Physical Chemistry A published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Quality Control of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hua, Ying-peng published the artcileCombined morpho-physiological, ionomic and transcriptomic analyses reveal adaptive responses of allohexaploid wheat (Triticum aestivum L.) to iron deficiency, Recommanded Product: (S)-2-Amino-4-(methylthio)butanoic acid, the publication is BMC Plant Biology (2022), 22(1), 234, database is CAplus and MEDLINE.

Plants worldwide are often stressed by low Fe availability around the world, especially in aerobic soils. Therefore, the plant growth, seed yield, and quality of crop species are severely inhibited under Fe deficiency. Fe metabolism in plants is controlled by a series of complex transport, storage, and regulatory mechanisms in cells. Allohexaploid wheat (Triticum aestivum L.) is a staple upland crop species that is highly sensitive to low Fe stresses. Although some studies have been previously conducted on the responses of wheat plants to Fe deficiency, the key mechanisms underlying adaptive responses are still unclear in wheat due to its large and complex genome. Transmission electron microscopy showed that the chloroplast structure was severely damaged under Fe deficiency. Paraffin sectioning revealed that the division rates of meristematic cells were reduced, and the sizes of elongated cells were diminished. ICP-MS-assisted ionmics anal. showed that low-Fe stress significantly limited the absorption of nutrients, including N, P, K, Ca, Mg, Fe, Mn, Cu, Zn, and B nutrients. High-throughput transcriptome sequencing identified 378 and 2,619 genome-wide differentially expressed genes (DEGs) were identified in the shoots and roots between high-Fe and low-Fe conditions, resp. These DEGs were mainly involved in the Fe chelator biosynthesis, ion transport, photosynthesis, amino acid metabolism, and protein synthesis. Gene coexpression network diagrams indicated that TaIRT1b-4A, TaNAS2-6D, TaNAS1a-6A, TaNAS1-6B, and TaNAAT1b-1D might function as key regulators in the adaptive responses of wheat plants to Fe deficiency. These results might help us fully understand the morpho-physiol. and mol. responses of wheat plants to low-Fe stress, and provide elite genetic resources for the genetic modification of efficient Fe use.

BMC Plant Biology published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Recommanded Product: (S)-2-Amino-4-(methylthio)butanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ma, Qiuyue published the artcileAssembly and comparative analysis of the first complete mitochondrial genome of Acer truncatum Bunge: a woody oil-tree species producing nervonic acid, Product Details of C5H11NO2S, the publication is BMC Plant Biology (2022), 22(1), 29, database is CAplus and MEDLINE.

Acer truncatum (purpleblow maple) is a woody tree species that produces seeds with high levels of valuable fatty acids (especially nervonic acid). The species is admired as a landscape plant with high developmental prospects and scientific research value. The A. truncatum chloroplast genome has recently been reported; however, the mitochondrial genome (mitogenome) is still unexplored. We characterized the A. truncatum mitogenome, which was assembled using reads from PacBio and Illumina sequencing platforms, performed a comparative anal. against different species of Acer. The circular mitogenome of A. truncatum has a length of 791,052 bp, with a base composition of 27.11% A, 27.21% T, 22.79% G, and 22.89% C. The A. truncatum mitogenome contains 62 genes, including 35 protein-coding genes, 23 tRNA genes and 4 rRNA genes. We also examined codon usage, sequence repeats, RNA editing and selective pressure in the A. truncatum mitogenome. To determine the evolutionary and taxonomic status of A. truncatum, we conducted a phylogenetic anal. based on the mitogenomes of A. truncatum and 25 other taxa. In addition, the gene migration from chloroplast and nuclear genomes to the mitogenome were analyzed. Finally, we developed a novel NAD1 intron indel marker for distinguishing several Acer species. In this study, we assembled and annotated the mitogenome of A. truncatum, a woody oil-tree species producing nervonic acid. The results of our analyses provide comprehensive information on the A. truncatum mitogenome, which would facilitate evolutionary research and mol. barcoding in Acer.

BMC Plant Biology published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Product Details of C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hahn, Dongyup published the artcileDetermination of sequence and absolute configuration of peptide amino acids by HPLC-MS/CD-based detection of liberated N-terminus phenylthiohydantoin amino acids, Recommanded Product: (S)-2-Amino-4-(methylthio)butanoic acid, the publication is Scientific Reports (2022), 12(1), 10285, database is CAplus and MEDLINE.

We report a method for the simultaneous determination of the sequence and absolute configuration of peptide amino acids using a combination of Edman degradation and HPLC-MS/CD. Phenylthiohydantoin (PTH) derivatives of 20 pairs of standard D- and L-amino acids were synthesized by the Edman reaction. The CD spectra of the derivatives revealed that each pair of the PTH derivatives exhibited the absorption with opposite signs at around 270 nm. These standard PTH derivatives showed well-resolved resolution without interference from byproducts in the ion chromatogram and clear pos./neg. CD absorptions when subjected on a reversed phase HPLC-MS system coupled with a CD-2095 HPLC detector. This method was applied for the detection of a synthetic pentapeptide and a natural depsipeptide (halicylindramide C). The sequence and configuration of the pentapeptide and up to eight residues of halicylindramide C were successfully analyzed by this method. The amino acid configuration of the pentapeptide was also determined successfully by subjecting its acid hydrolyzates to the Edman reaction followed by HPLC-MS/CD.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Recommanded Product: (S)-2-Amino-4-(methylthio)butanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia