Tag: M.W=200-250

Niknam, K. published the artcileSynthesis of 2-substituted benzimidazoles and bis-benzimidazoles by microwave in the presence of alumina-methanesulfonic acid, SDS of cas: 5411-14-3, the publication is Journal of the Iranian Chemical Society (2007), 4(4), 438-443, database is CAplus.

A microwave-assisted method for the synthesis of 2-substituted benzimidazoles in the presence of alumina-methanesulfonic acid (AMA) is reported. In addition, by this method some new bis-benzimidazoles, e.g., I (X = O, S), from the direct reaction of 1,2-phenylenediamine and dicarboxylic acid under microwave irradiation in good to excellent yields are described.

Journal of the Iranian Chemical Society published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, SDS of cas: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Leong, Sze Wei published the artcileSynthesis and SAR study of diarylpentanoid analogues as new anti-inflammatory agents, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Molecules (2014), 19(10), 16058-16081, 24 pp., database is CAplus and MEDLINE.

A series of ninety-seven diarylpentanoid derivatives I (R = H, 4-Cl, 4-Br, 5-OCH₃, 3,5-(OCH₃)₂, 4-OCH₃, 4,6-(Cl)₂; Ar = 3,4,5-trimethoxyphenyl, 2-chlorophenyl, 1-naphthyl, 2-furyl, 5-chloro-2-thienyl, etc.) were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using interferon gamma (IFN-¦Ã)/lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Some of the compounds I exhibited greater or similar NO inhibitory activity in comparison with curcumin (14.7 ¡À 0.2 ¦ÌM), notably compounds I (R = 4-Cl; Ar = 2,3-(OH)₂-C₆H₃) and I (R = H; Ar = 2,3-(OH)₂-C₆H₃), which demonstrated the most significant NO suppression activity with IC₅₀ values of 4.9 ¡À 0.3 ¦ÌM and 9.6 ¡À 0.5 ¦ÌM, resp. A structure-activity relationship (SAR) study revealed that the presence of a hydroxyl group in both aromatic rings is critical for bioactivity of these mols. With the exception of the polyphenolic derivatives, low electron d. in ring-A and high electron d. in ring-B are important for enhancing NO inhibition. The pharmacophore mapping showed that hydroxyl substituents at both meta- and para-positions of ring-B could be the marker for highly active diarylpentanoid derivatives

Molecules published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Aristov, B. G. published the artcileAdsorption of amines from aqueous solutions on copper phthalocyanine, Synthetic Route of 2016-56-0, the publication is Zhurnal Fizicheskoi Khimii (1979), 53(7), 1859-62, database is CAplus.

The adsorption of pentyl-, hexyl-, and octylamine and octylammonium and dodecylammonium acetates on ¦Â-phthalocyanine dyes was studied in aqueous solutions The adsorption capacity (a_m) and the surface area, occupied by adsorbed amine mols. on Cu phthalocyanine (I), were determined The large a_m value for pentylamine is explained by specific interaction (an addnl. to the dispersion) of pentylamine mols. on 010 lattice of I. The structure of the adsorbed layer is discussed. For I, the distance between the adsorption centers is ?7.2 ?.

Zhurnal Fizicheskoi Khimii published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Synthetic Route of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Yan published the artcileAu(III)-catalyzed intermolecular amidation of benzylic C-H bonds, Name: Bis(4-fluorophenyl)methane, the publication is Organic & Biomolecular Chemistry (2012), 10(46), 9137-9141, database is CAplus and MEDLINE.

Au(III)-catalyzed intermol. amidations of benzylic C-H bonds with sulfonamides and carboxamides are described. The protocol with the Au-bipy complex/N-bromosuccinimide system provides practical applications for synthesis of various amides via C-H activations. The reaction proceeds with high efficiency to give the corresponding amines, which are extremely useful synthetic intermediates.

Organic & Biomolecular Chemistry published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C10H18O4, Name: Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dai, Wei-Min published the artcileSynthesis of C3-C12 fragment of 24-demethylbafilomycin C₁ via anti-selective aldol condensation as the key stereocontrol step, SDS of cas: 4141-48-4, the publication is Synlett (2008), 1013-1016, database is CAplus.

An efficient synthesis of the C(3)-C(12) aldehyde fragment of 24-demethylbafilomycin C₁ was accomplished for assembling the 16-membered plecomacrolide skeleton according to a 1,3-diene-ene ring-closing metathesis (RCM) strategy. A boron-mediated anti-selective aldol condensation of Abiko’s chiral propionate was used to secure the C(6) and C(7) stereogenic centers while the C(8) chirality was introduced from a chiral building block. The dithiane alkylation and the Me ketone Horner-Wittig olefination using allyldiphenylphosphine oxide were employed for construction of the requisite (E)-1,3-diene subunit.

Synlett published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, SDS of cas: 4141-48-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Scherner, Cathrin published the artcileA novel route to 6-substituted piperidin-3-ols via domino cyclization of 2-hydroxy-6-phosphinyl-5-hexenyl tosylates with primary amines: synthesis of (¡À)-pseudoconhydrine and (¡À)-epi-pseudoconhydrine, Recommanded Product: Allyldiphenylphosphine oxide, the publication is Synthesis (2014), 46(18), 2506-2514, database is CAplus.

2-Hydroxy-6-phosphinyl-5-hexenyl tosylates, oxirane ring-opening products derived from glycidyl tosylates and phosphinyl- substituted allyl anions, undergo domino S_N2-Michael reactions with primary amines to give 6-phosphinylmethyl piperidin-3-ols. The phosphinyl unit can be used in Horner olefination reactions. This approach is applied to the synthesis of racemic pseudoconhydrine (I) and its epimer II.

Synthesis published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Recommanded Product: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Fedorov, Andrei V. published the artcileNew Method To Reduce Oxygen Surface Inhibition by Photorelease of Boranes from Borane/Amine Complexes, Related Products of catalysis-chemistry, the publication is Macromolecules (Washington, DC, United States) (2007), 40(10), 3554-3560, database is CAplus.

A new photochem. approach for free radical polymerization has been developed. The system releases trialkylborane from its complex with 4-(dimethylamino)pyridine upon irradiation The presence of a free borane in the formulation, when it encounters oxygen, promotes radical polymerization The system, when irradiated by an ergonomic 395 nm LED array, is able to efficiently overcome surface oxygen inhibition. The properties of the resulting photopolymer surfaces either matched or exceeded those of controls polymerized under N₂ atmosphere or with high-intensity light source. Results of exptl. and computational studies probing the mechanism of borane photorelease are also discussed. Safety consideration, all reagents and reaction mixture in synthesis af amine-borane complexes should be kept under dry Ar atm. since triethylborane is pyrophoric.

Macromolecules (Washington, DC, United States) published new progress about 2909-77-5. 2909-77-5 belongs to catalysis-chemistry, auxiliary class Amine,Benzene, name is 2,6-Diisopropyl-N,N-dimethylaniline, and the molecular formula is C14H23N, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Stache, Erin E. published the artcileGeneration of Phosphoranyl Radicals via Photoredox Catalysis Enables Voltage-Independent Activation of Strong C-O Bonds, Formula: C15H24S, the publication is ACS Catalysis (2018), 8(12), 11134-11139, database is CAplus and MEDLINE.

Benzylic alcs. and aryl and alkylcarboxylic acids underwent photochem. deoxygenative reduction via phosphoranyl radicals in the presence of an iridium photoredox catalyst, either Ph₃P or Ph₂POEt, and an aryl disulfide or thiol to yield methylarenes and aryl and alkyl aldehydes. Carboxylic acids with pendant carbonyl groups or alkenes underwent cyclization reactions via acyl radicals in the presence of the iridium photoredox catalyst, Ph₂POEt, and an aryl thiol to yield lactones, a lactam, and cyclic ketones.

ACS Catalysis published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C4H11NO, Formula: C15H24S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Weidlich, Frauke published the artcileMild C-F Activation in Perfluorinated Arenes through Photosensitized Insertion of Isonitriles at 350 nm, Application In Synthesis of 1206-46-8, the publication is Advanced Synthesis & Catalysis (2020), 362(2), 376-383, database is CAplus.

Herein a method for the photochem. activation of aromatic C-F bonds is presented. It is shown that isonitriles RNC (R = 9-oxo-9H-xanthen-2-yl, 1-phenylethan-1-one, 2H-1,3-benzodioxol-5-yl, etc.) selectively insert into aromatic C-F bonds while aliphatic C-F bonds remain unaffected. Mechanistic studies reveal the reaction to proceed via the indirect excitation of the isonitrile to its triplet state by photoexcited acetophenone at 350 nm. Due to the relatively mild light used, the process shows that high functional group tolerance and various compounds of the class of benzimidoyl fluorides (Z)-RN=C(F)R¹ (R¹ = pentafluorophenyl, tetrafluoropyridin-3-yl, 3-chloro-2,4,5,6-tetrafluorophenyl, etc.) are accessible from aryl isonitriles and com. available perfluorinated arenes such as hexafluorobenzene, Me pentafluorobenzoate, perfluoropyridine, etc.

Advanced Synthesis & Catalysis published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C8H15NO, Application In Synthesis of 1206-46-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Antoshin, A. E. published the artcileSynthesis and complex-forming properties of methyl- and dimethyl-substituted ethylenediphosphine dioxides, Synthetic Route of 4141-48-4, the publication is Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya (1991), 1860-5, database is CAplus.

Treating Ph₂P(O)H with XCH₂CR:CH₂ (X = Br, R = H; X = Cl, R = Me) in C₆H₆ containing aqueous KOH or aqueous KOH and a catalytic amount of Bu₄NBr gave Ph₂P(O)CH:CRMe (I; same R) or 56-75%. Ph₂P(O)CH₂CR:CH₂, resp. Reaction of I with R¹₂P(O)H (R¹ = 4-tolyl, Et, octyl, PhCH₂) in DMSO containing KOH gave 50-91% title ethylenebisphosphine dioxides Ph₂P(O)CH₂CRMeP(O)R¹₂ (II; same R, R¹) which were tested for complexation with alkali metal cations. The highest Li/Na selectivity was observed for II (R = Me, R¹ = octyl).

Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Synthetic Route of 4141-48-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia