Tag: M.W=200-250

Nelson, Adam published the artcileAsymmetric dihydroxylation of allylic phosphine oxides, Category: catalysis-chemistry, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1997), 2645-2657, database is CAplus.

Diphenylphosphinoyl diols have been produced by asym. dihydroxylation (AD) of allylic phosphine oxides and have been useful synthetic intermediates. The results of this study are discussed in terms of the model which has been proposed by Sharpless to explain the enantioselectivity of his AD reaction. Thus, Sharpless asym. dihydroxylation of (E)-1-diphenylphosphinoylbut-2-ene (preparation given) in the presence of AD-mix-¦Á/sulfonamide in alc./water gave 84% (2R,3S)-1-diphenylphosphinoylbutane-2,3-diol. The dihydroxylation results are thus of both mechanistic and synthetic value.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nokami, Toshiki published the artcileElectrochemical synthesis of dendritic diarylcarbenium ion pools, Quality Control of 457-68-1, the publication is Tetrahedron (2011), 67(25), 4664-4671, database is CAplus.

Dendritic diarylcarbenium ion pools were synthesized by the low temperature electrochem. oxidation of the corresponding dendritic (diarylmethyl)trimethylsilanes, which were prepared by use of the iterative method consisting of electrochem. activation and Friedel-Crafts type coupling. Time-course NMR studies revealed that thermal stability of dendritic diarylcarbenium ions depends both on the generation of the dendritic structure and on the para-substituents of the terminal Ph groups. Dendritic diarylcarbenium ions up to the third generation exhibited high reactivity as a carbon electrophile.

Tetrahedron published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Quality Control of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Terao, Kimitada published the artcileA new highly sterically demanding silyl (TEDAMS) group. Synthesis by multiple substitution of tris(diphenylmethyl)silane with diarylcarbenium ions, Application of Bis(4-fluorophenyl)methane, the publication is Tetrahedron Letters (2010), 51(31), 4107-4109, database is CAplus.

A highly efficient electrochem. method for synthesis of halosilanes bearing bulky substituents was developed. Electrophilic multiple substitution on tris(diphenylmethyl)silane with diarylcarbenium ions afforded a highly sterically demanding hydrosilane, tris(extended diarylmethyl)silane (TEDAMS-H), which was converted to the corresponding bromosilane (TEDAMS-Br).

Tetrahedron Letters published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C16H12O, Application of Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nokami, Toshiki published the artcileMultiple alkylation of thiophene derivatives with simple and extended diarylcarbenium ion pools, Synthetic Route of 457-68-1, the publication is Electrochemistry (Tokyo, Japan) (2013), 81(5), 399-401, database is CAplus.

The reactions of thiophene derivatives, bithiophene, and terthiophene with an electrochem. generated diarylcarbenium ion pool afforded multiple alkylation products. Extended diarylcarbenium ion pools afforded dendritic mols. by the multiple alkylation of bithophene and terthiophene.

Electrochemistry (Tokyo, Japan) published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Synthetic Route of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ito, Kazuya published the artcileCoordination hybrid of silsesquioxane containing phosphine oxide and an europium complex, Recommanded Product: Allyldiphenylphosphine oxide, the publication is Kobunshi Ronbunshu (2010), 67(7), 412-415, database is CAplus.

A phosphorescent coordination hybrid was successfully prepared from silsesquioxane containing phosphine oxide and Eu tris ¦Â-diketonate. The novel silsesquioxane was synthesized by the sol-gel reaction of corresponding trialkoxysilane obtained by the ene-thiol reaction of allyldipenylphosphine oxide and mercaptopropyltriethoxysilane. Despite the high concentration of the Eu complex (50%), the complex was dispersed completely into the silsesquioxane, giving a dense, homogeneous, and transparent hybrid thin film. The luminescence property of this film was also studied. This hybrid thin film with the embedded Eu complex shows bright phosphorescence accompanied with a characteristic sharp spectrum derived from the f-f transition of Eu at ambient temperature The enhancement of the emission intensity and the branching ratio for the Eu complex in the hybrid compared to the Eu complex in PMMA is due to the formation of a coordination bond between the Eu complex and the phosphine oxide in silsesquioxane.

Kobunshi Ronbunshu published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Recommanded Product: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Singh, Govind P. published the artcileAchiral 2-Hydroxy Protecting Group for the Stereocontrolled Synthesis of 1,2-cis-¦Á-Glycosides by Six-Ring Neighboring Group Participation, Application of 2,4,6-Trimethoxybenzenethiol, the publication is Organic Letters (2015), 17(17), 4376-4379, database is CAplus and MEDLINE.

Glycosylation of a fully armed donor bearing a 2-O-(trimethoxybenzenethiol) Et ether protecting group is completely ¦Á-selective with a range of carbohydrate alc. acceptors. Low-temperature NMR studies confirm the intermediacy of cyclic sulfonium ion intermediates arising from six-membered ¦Â-sulfonium ring neighboring group participation. Selective protecting group removal is achieved in high yield in a single operation by S-methylation and base-induced ¦Â-elimination.

Organic Letters published new progress about 77189-99-2. 77189-99-2 belongs to catalysis-chemistry, auxiliary class Thiophenol,Benzene,Ether, name is 2,4,6-Trimethoxybenzenethiol, and the molecular formula is C8H6ClN, Application of 2,4,6-Trimethoxybenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Manos-Turvey, Alexandra published the artcileSynthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents, HPLC of Formula: 31719-76-3, the publication is MedChemComm (2015), 6(3), 403-406, database is CAplus.

The synthesis and anti-trypanosomal activity of a compound library based on a phenoxymethylbenzamide hit discovered in a high throughput screen is described. Several of the analogs exhibited potent activity against Trypanosoma brucei rhodesiense, a human infective strain of the trypanosome parasite, that serve as lead compounds for further optimization.

MedChemComm published new progress about 31719-76-3. 31719-76-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 4-(Phenoxymethyl)benzoic acid, and the molecular formula is C14H12O3, HPLC of Formula: 31719-76-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tai, Xi-Shi published the artcileSynthesis, structural characterization and electrochemical property of a dinuclear Cu (II) complex material, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Open Materials Science Journal (2015), 210-213, database is CAplus.

A novel dinuclear Cu(II) complex material has been synthesized by the reaction of 1, 2-phenylenedioxydiacetic acid, 1,10-phenantroline (phen) and Cu(CH₃COO)₂¡¤H₂O. And it has been characterized by elemental anal., IR, UV and single crystal X-ray diffraction. The crystal belongs to tetragonal, space group I4₁/a with a = b = 25.381(4) ?, c = 32.044(6) ?, V = 20643(6) ?³, Z = 16, Dc= 1.395 g¡¤cm^-3, ¦Ì = 0.898 mm^-1, F (000) = 8896, and final R = 0.1026, ¦ØR = 0.3142. The structural anal. shows that two Cu(II) atoms adopt different coordination modes, Cu¹ has five-coordination with a trigonal bipyramidal configuration, and Cu² has four-coordination with a distorted square planar configuration. The cyclic voltammetric behavior of the dinuclear Cu(II) complex has been investigated.

Open Materials Science Journal published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C7H4BrClO2, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Zheng published the artcileDesign, synthesis and structure-activity relationship studies of novel phenoxyacetamide-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes, Category: catalysis-chemistry, the publication is Bioorganic & Medicinal Chemistry (2015), 23(20), 6666-6672, database is CAplus and MEDLINE.

The free fatty acid receptor 1 (FFA1) has attracted extensive attention as a novel antidiabetic target in the last decade. Several FFA1 agonists reported in the literature have been suffered from relatively high mol. weight and lipophilicity. We have previously reported the FFA1 agonist 1. Based on the common amide structural characteristic of SAR1 and NIH screened compound, we here describe the continued structure-activity exploration to decrease the mol. weight and lipophilicity of the compound 1 series by converting various amide linkers. All of these efforts lead to the discovery of the preferable lead compound 18, a compound with considerable agonistic activity, high LE and LLE values, lower lipophilicity than previously reported agonists, and appreciable efficacy on glucose tolerance in both normal and type 2 diabetic mice.

Bioorganic & Medicinal Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ding, Peipei published the artcileSynthesis of heterobinuclear Cu(II)-Ni(II) complex: Structure, CT-DNA interaction, hydrolytic function and antibacterial studies, HPLC of Formula: 140-28-3, the publication is Journal of Molecular Structure (2019), 836-843, database is CAplus.

A new benzyls pendant-armed macrobicyclic heterbinuclear Cu(II)-Ni(II) complex has been obtained by template-directed synthesis and characterized by elemental anal., IR spectra, electrospray mass spectra, and single crystal x-ray diffraction. The complex was bridged by two phenolic oxygens and an acetate radical, with the Cu(II)-Ni(II) distance of 2.9292(8) ?. The hydrolytic function, CT-DNA binding and antibacterial properties were also studied. The initial rate values for the hydrolysis of 4-nitrophenylphosphate to 4-nitrophenolate by the Cu(II)-Ni(II) complex was 1.33 ¡Á 10^-5 s^-1, and 10⁴ times faster than that the spontaneous hydrolysis of the phosphate monoester. The complex shows a better binding property to CT-DNA and the intrinsic binding constant is 1.29 ¡Á 10⁵ M^-1. The Stern-Volmer constant is 1.25 ¡Á 10⁵ M^-1. The viscosity increased obviously with the increase of complex concentration, the results showed that the complex bind to DNA through intercalation mode, which was in accordance with the absorption and emission spectral studies. The antibacterial activities against E.coli was also investigated using the Gentamycinas reference system.

Journal of Molecular Structure published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, HPLC of Formula: 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia