Tag: M.W=200-250

Sunitha, Pg published the artcileDevelopment of novel stability indicating RP-HPLC method for quantification of trientine hydrochloride and characterization of its degradation product by spectroscopic techniques, Application In Synthesis of 38260-01-4, the publication is Research Journal of Pharmaceutical, Biological and Chemical Sciences (2019), 10(3), 211-223, database is CAplus.

The present work reports the development of a novel stability indicating RP-HPLC method for the quantification of Trientine hydrochloride. The stability of Trientine hydrochloride was studied under different stress conditions recommended by ICH guidelines. Trientine contains amino group which makes it vulnerable to oxidative degradation The chromatog. separation of the drug and its degradation product was achieved in a Waters Reliant C8 column (250mm ¡Á 4.0mm ID, 4¦Ìm particle size) employing gradient elution using Acetronitrile and Ammonium formate buffer at pH 5.3 ¡À 0.05 (90:10) volume/volume, at a flow rate of 0.8mL/min and detection performed at 220 nm. The develop method has been validated as per ICH guidelines. Structural characterization and identification of the degradation product was done by LC-MS, 1H NMR, 13C NMR and IR spectroscopic studies. Toxicity prediction for the degradation product was achieved using the Software OSIRIS.

Research Journal of Pharmaceutical, Biological and Chemical Sciences published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C7H7ClN2S, Application In Synthesis of 38260-01-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Naciuk, Fabricio F. published the artcileOne pot domino reaction accessing ¦Ã-nitroesters: synthesis of GABA derivatives, Related Products of catalysis-chemistry, the publication is New Journal of Chemistry (2015), 39(3), 1643-1653, database is CAplus.

Michael addition of 1,3-dicarbonyl compounds to nitrostyrenes is efficiently promoted by hydrotalcite [Mg-Al] to afford the resp. ¦Ã-nitrodicarbonyl adducts. Differently, the addition of Meldrum’s acid leads to a direct access of ¦Ã-nitroesters through a one pot domino process. GABA derivatives (+/-)-phenibut and (+/-)-baclofen were readily synthesized from the resp. nitro adducts.

New Journal of Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kormachev, V. V. published the artcilePhosphorus-containing intermediates and dyes. IX. Syntheses based on aryldichloro- and diarylchlorophosphines, Formula: C15H15OP, the publication is Zhurnal Obshchei Khimii (1988), 58(4), 770-6, database is CAplus.

Bis(aminoaryl)alkylphosphine oxide intermediates for azo dyes were obtained in high yields by addition of alkyl halides to chlorodiarylphosphines, conversion of the crystalline dihalophosphorane intermediates to phosphine oxides with alcs., nitration of the phosphine oxides, and reduction of the nitro groups. The reaction of bis[2-(N-ethyl-N-phenylamino)ethyl] phenylphosphonite with EtI occurred under mild conditions only at the P atom to give 2-(N-ethyl-N-phenylamino)ethyl ethylphenylphosphinate. Azo coupling of the P-containing primary and tertiary aromatic amines gave new types of dyes with good dyeing properties.

Zhurnal Obshchei Khimii published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Formula: C15H15OP.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sundararaju, Kavya published the artcileSynthesis of palladium nanoparticles using triazolium based ionic liquids: A reusable catalyst for addition of arylboronic acids to nitrostyrenes, Synthetic Route of 4230-93-7, the publication is Synthetic Communications (2018), 48(23), 3000-3014, database is CAplus.

Palladium nanoparticles containing an octyltriazolium trifluoroacetate ionic liquid were prepared as a recyclable catalyst for the addition of arylboronic acids to ¦Â-nitrostyrenes to give diarylnitroethanes.

Synthetic Communications published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C3H8N2S, Synthetic Route of 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nakamura, Shinji published the artcileRegio- and Chemoselective Silylmetalation of Functionalized Terminal Alkenes, Quality Control of 4141-48-4, the publication is Journal of the American Chemical Society (2007), 129(1), 28-29, database is CAplus and MEDLINE.

A regio-/chemoselective silylmetalation of various functionalized alkenes, e.g. I, based on the zinc silyl complex in the presence of a catalytic amount of copper cyanide was developed. Silylmetalation of alkenes, followed by electrophilic trapping, proved to be a powerful tool for the functionalization of the continuous carbon atoms of the alkenes. The resultant alkylsilanes, e.g. II, can be converted smoothly into alcs., e.g. III, by oxidative cleavage of the carbon-silicon bond.

Journal of the American Chemical Society published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Quality Control of 4141-48-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dohi, Toshifumi published the artcileSelective carboxylation of reactive benzylic C-H bonds by a hypervalent iodine(III)/inorganic bromide oxidation system, Application In Synthesis of 457-68-1, the publication is Beilstein Journal of Organic Chemistry (2018), 1087-1094, database is CAplus and MEDLINE.

An oxidation system comprising phenyliodine(III) diacetate (PIDA) and iodosobenzene with sodium bromide in DCM led to the direct introduction of carboxylic acids into benzylic C-H bonds, for the formation corresponding esters e.g. I under mild conditions. The unique radical species, generated by the homolytic cleavage of the labile I(III)-Br bond of the in situ-formed bromo-¦«³-iodane, initiated benzylic carboxylation with a high degree of selectivity for the secondary benzylic position.

Beilstein Journal of Organic Chemistry published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Application In Synthesis of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nakai, Satoru published the artcileAerobic Oxygenation of Alkylarenes over Ultrafine Transition-Metal-Containing Manganese-Based Oxides, Name: Bis(4-fluorophenyl)methane, the publication is ChemCatChem (2018), 10(5), 1096-1106, database is CAplus.

An efficient alkylarene oxygenation process catalyzed by ultrafine transition-metal-containing Mn-based oxides with spinel or spinel-like structures (M-MnO_x, M = Fe, Co, Ni, Cu) for the synthesis of aryl ketones was developed. These M-MnO_x catalysts were prepared by a low-temperature reduction method in 2-propanol-based solutions using tetra-Bu ammonium permanganate (TBAMnO₄) as the Mn source, and they exhibited high Brunauer-Emmett-Teller surface areas (typically >400 m² g^-1). Using fluorene as the model substrate, the catalytic activities of M-MnO_x and Mn₃O₄ were compared. The catalytic activities of M-MnO_x were significantly higher than that of Mn₃O₄, thus indicating that the incorporation of transition metals in manganese oxide was critical Among the series of M-MnO_x catalysts examined, Ni-MnO_x exhibited the highest catalytic activity for the oxygenation. In addition, the catalytic activity of Ni-MnO_x was higher than that of a phys. mixture of Mn₃O₄ and NiO. Furthermore, Ni-MnO_x exhibited a broad substrate scope with respect to various types of structurally diverse (hetero)alkylarenes (16 examples). The observed catalysis was truly heterogeneous, and the Ni-MnO_x catalyst was reusable for the oxygenation of fluorene at least three times and its high catalytic performance was preserved, for example, the reaction rate, final product yield, and product selectivity. The present Ni-MnO_x-catalyzed oxygenation process is possibly initiated by a single-electron oxidation process, and herein a plausible oxygen-transfer mechanism is proposed based on several pieces of exptl. evidence.

ChemCatChem published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Name: Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ikeda, Yoshihiko published the artcileStereoselective synthesis of (Z)- and (E)-1,3-alkadienes from aldehydes using organotitanium and lithium reagents, Recommanded Product: Allyldiphenylphosphine oxide, the publication is Tetrahedron (1987), 43(4), 723-30, database is CAplus.

[3-(Diphenylphosphino)allyl]titanium reagent generated easily from allyldiphenylphosphine (I) condenses with aldehydes to give (Z)-1,3-alkadienes in high regio- and stereoselectivity. In contrast, lithiated I oxide condenses with aldehydes to give (E)-1,3–alkadienes directly and stereoselectively in good yields. Similarly, lithiated (1-buten-3-yl)diphenylphosphine oxide condenses with aldehydes to give (E)-3-methyl-1,3-alkadienes.

Tetrahedron published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Recommanded Product: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Takeda, S. published the artcileCationic flotation of quartz from an artificial mixture with hematite using hexylamine, Category: catalysis-chemistry, the publication is Colloids and Surfaces (1988), 29(2), 221-32, database is CAplus.

The cationic flotation of quartz was carried out from an artificial mixture (1:1 by weight) of fine grained (-10 ¦Ìm) quartz and hematite, using hexylamine acetate (HAA) and dodecylamine acetate (DAA) as collectors. Selective flotation of quartz was possible in the pH range 9-10 using HAA. The adsorption densities of DAA and HAA on quartz and hematite were measured at pH 9.8 and the relation between the flotation behavior of both minerals and the surface coverage of collectors was established. Complete flotation of quartz and hematite required a surface coverage (¦È) of DAA of ?100% at pH 9.8, while complete flotation of quartz took place at ¦È ? 10% with HAA. The flotation behavior with DAA was explained by considering the adsorption of undissociated free amine. Zeta potential measurements were incorporated to interpret the difference in the adsorption behavior of both collectors on quartz and hematite.

Colloids and Surfaces published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C10H10N2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Takeda, Susumu published the artcileFlotation separation of coarse-grained quartz from a mixture with hematite fines in alkaline media in relation to the adsorption of dodecylammonium acetate, Application In Synthesis of 2016-56-0, the publication is Nippon Kogyo Kaishi (1987), 103(1198), 859-64, database is CAplus.

Flotation separation of coarse-grained quartz with dodecylammonium acetate as the collector is interfered with when fine-grained hematites coexist. The reason for this was investigated. Both quartz and hematite become hydrophobic by adsorption of dodecylammonium acetate, and the hematite fines coat the surfaces of the quartz grains. The slime coating may cause the depression of quartz flotation.

Nippon Kogyo Kaishi published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C9H5ClO2, Application In Synthesis of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia