Tag: M.W=200-250

Spearin, E. Y. published the artcileSurface and flotation properties of silver chloride as a function of induced point defects, Formula: C14H31NO2, the publication is Colloids and Surfaces (1987), 257-71, database is CAplus.

AgCl has a Frenkel-type disorder which consists of cation interstitials and an equivalent number of cation vacancies. Zeta potential, critical surface tension of wetting, contact angle, and flotation studies over a broad range of pAg and in the presence and absence of cationic and anionic surfactants were made. Cd-doping has a profound effect on all of these properties. Such doping makes the surface less hydrophobic for both the bare solid and the solid with either cationic or anionic adsorbed surfactants.

Colloids and Surfaces published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C11H21BF4N2O2, Formula: C14H31NO2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yu, Zhiyi published the artcileDesign, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid derivatives, Application In Synthesis of 1798-04-5, the publication is European Journal of Medicinal Chemistry (2009), 44(11), 4726-4733, database is CAplus and MEDLINE.

A series of 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid (norfloxacin) derivatives I (R = 2-furanyl, 3-pyridinyl, 2-ClC₆H₄OCH₂, etc.) were prepared according to the principle of combining bioactive substructures, and tested for activity against five plant pathogenic bacteria and three fungi in vitro. The preliminary bioassays indicated that almost all the synthesized target compounds retained the antibacterial activities of norfloxacin and had some antifungal activities as seen with carboxamide compounds The activities of compounds I (R = 2-furanyl, Ph) against Xanthomonas oryzae were better than norfloxacin and all tested compounds had better antibacterial activities as compared to the agricultural streptomycin sulfate (a com. bactericide) against X. oryzae, Xanthomonas axonopodis and Erwinia aroideae. Addnl., compounds I [R = (E)-2-(5-methylfuran-2-yl)ethenyl, (E)-4-MeOC₆H₄CH:CH] displayed good antifungal activities against Rhizoctonia solani and their inhibition of growth reached 83% and 94% resp. at the concentration of 200 mg/L.

European Journal of Medicinal Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C10H18O, Application In Synthesis of 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Niu, Changrong published the artcileSynthesis of bisamide bisester-bis(crown ether) compounds, Application In Synthesis of 5411-14-3, the publication is Wuhan Daxue Xuebao, Ziran Kexueban (1998), 44(6), 711-713, database is CAplus.

Three new bisamides-bis(crown ether) compounds I (ortho, meta, para) are synthesized by the reaction of o, m, p-phenylenedioxydiacetyl dichloride with 4′-aminobenzo-15-crown-5; three new bisesters-bis(crown ether) compounds are synthesized by the condensation of o, m, p-phenylenedioxydiacetyl dichloride with 6-hydroxyldibenzo-16-crown-5.

Wuhan Daxue Xuebao, Ziran Kexueban published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Application In Synthesis of 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Matsufuji, Tetsuyoshi published the artcileSynthesis and biological evaluation of novel chiral diazepine derivatives as bombesin receptor subtype-3 (BRS-3) agonists incorporating an antedrug approach, Recommanded Product: 2-(3-(Benzyloxy)phenyl)acetic acid, the publication is Bioorganic & Medicinal Chemistry (2015), 23(1), 89-104, database is CAplus and MEDLINE.

Novel compounds based on the lead BRS-3 agonists from our HTS compounds have been synthesized with the focus on obtaining peripheral BRS-3 agonists. To identify potent anti-obesity compounds without adverse effects on the central nerve system, a labile carboxylic ester with an antedrug functionality was introduced onto the terminal position. Through the extensive synthetic exploration and the pharmacokinetic studies of oral administration in mice, the phenol ester I was selected due to the most suitable pharmacol. profile. In the evaluation of food intake suppression in B6 mice, I showed significant in vivo efficacy and no clear adverse effect on heart rate and blood pressure change in dog iv infusion. Our study paved the way for development of anti-diabetes and obesity drugs with a safer profile.

Bioorganic & Medicinal Chemistry published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Recommanded Product: 2-(3-(Benzyloxy)phenyl)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Matsufuji, Tetsuyoshi published the artcileDiscovery of novel chiral diazepines as bombesin receptor subtype-3 (BRS-3) agonists with low brain penetration, Formula: C15H14O3, the publication is Bioorganic & Medicinal Chemistry Letters (2014), 24(3), 750-755, database is CAplus and MEDLINE.

The discovery and optimization of a novel series of BRS-3 agonists are described. We explored a potent BRS-3 agonist with low brain penetration to avoid an adverse effect derived from central nervous system exposure. Through the derivatization process, chiral diazepines I (R¹ = iso-Bu, 2-methylpyridin-5-yl) were identified as possessing low brain penetration as well as potent in vitro activity against human and mouse BRS-3s.

Bioorganic & Medicinal Chemistry Letters published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Formula: C15H14O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Komoda, Kazuki published the artcileSolvent-Promoted Catalyst-Free Nucleophilic Fluoroalkylation of Aldehydes, Recommanded Product: Trimethyl(perfluorophenyl)silane, the publication is ChemistrySelect (2019), 4(8), 2374-2378, database is CAplus.

Fluoroalkyl silanes are useful building blocks for nucleophilic introduction of fluoroalkyl groups into organic mols. In general, fluoroalkyl silanes per se are stable compounds, but they are amenable to reactions as fluoroalkyl anion equivalent in the presence of base such as fluoride ion. Usually, KF acts as a good catalyst for nucleophilic fluoroalkylation of carbonyl compounds To avoid the use of hygroscopic fluoride salts, we have developed a convenient catalyst-free method for nucleophilic fluoroalkylation of aldehydes and ketones by the use of fluoroalkyl silanes. Trifluoromethyl(trimethyl)silane (Me₃Si-CF₃), and other fluoroalkyl silanes (Me₃Si-R_f) underwent solvent-promoted nucleophilic addition to aldehydes smoothly to give fluoroalkylated alcs. in good yields. In the present reactions, the use of polar solvents such as DMSO, DMF or NMP is essential to the formation of 1,2-adducts.

ChemistrySelect published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Recommanded Product: Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nagasaki, Takeshi published the artcileSynthesis and solvent extraction studies of novel calixarene-based uranophiles bearing hydroxamic groups, SDS of cas: 1798-04-5, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) (1991), 1063-6, database is CAplus.

Calix[n]arene-based uranophiles [I; n = 4 (II), 6 (III)] bearing hydroxamic groups on the lower rim have been synthesized and the extractability (Ex%) and the selectivity towards uranyl ion (UO₂²⁺) estimated in a two-phase (water-chloroform) solvent extraction system. Ex% for II and III increases from pH 2 and saturation is reached at around pH 5 where 100% extractability occurs. Since the pK_a values for hydroxamic acids are 8-9, the apparent pK_a shift caused by the UO₂²⁺-complexation amounts to 6-7 pK units. Extraction of UO₂²⁺ from aqueous carbonate solution established that III in the organic phase can compete efficiently with CO₃^2- ions in the aqueous phase for UO₂²⁺ whereas in II and a calix[6]arene-based uranophile bearing six carboxy groups, UO₂²⁺ is reextracted to the aqueous phase. The difference indicates that III which has the hexacoordination geometry preorganized for the binding of UO₂²⁺, is superior to II as a uranophile. The selectivity of III is superior to the uranophile bearing six carboxy groups. The Ex% values for III are scarcely affected by the addition of competing metal cations (except Fe³⁺). These results shows that III serves as an excellent UO₂²⁺-selective extraction reagent.

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, SDS of cas: 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nagasaki, Takeshi published the artcileSolvent extraction of transition metal cations by calixarene-based cyclic ligands, Computed Properties of 1798-04-5, the publication is Bulletin of the Chemical Society of Japan (1992), 65(2), 471-5, database is CAplus.

Calix[n]arenes (n =4 and 6) bearing carboxyl group (1_n), hydroxamate groups (2_n), and dimethylamino groups (3_n) on the lower rim and their monomeric analogs (1₁, 2₁, and 3₁) were synthesized to estimate selective extraction of transition metal cations from the aqueous phase to the organic (chloroform) phase. 1₄ And 1₆ showed the selectivity toward Fe³⁺, Cu²⁺, Zn²⁺, and Pd²⁺. In particular, 1₆ showed the unusually high extractability toward Fe³⁺. 2₄ And 2₆ showed the selectivity toward Fe³⁺, Cu²⁺, and Pd²⁺, but only Fe³⁺ was extracted to a significant extent at pH 2.2, the order of the extractability being 2₆ > 2₄ > 2₁. 3₄ And 3₆ showed the selectivity toward Pd²⁺ and Pt⁴⁺. The detailed examination of the extraction mechanism established that the ion-pair extraction mechanism is operative in Pt⁴⁺ (i.e., extracted as [PtCl₆]^2-) whereas both the ion-pair extraction mechanism and the chelate-complex extraction mechanism are operative in Pd²⁺ i.e., extracted as [PdCl₄]^2- in the ion-pair extraction mechanism). The results indicate that the ligand groups circularly arranged on the lower rim of the calixarene cavity form novel binding sites for transition metal cations.

Bulletin of the Chemical Society of Japan published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Computed Properties of 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yamamoto, Hirofumi published the artcileHg(OTf)₂-catalyzed cycloisomerization of aryl- and hetero-substituted 1,3-dienes, Recommanded Product: Allyldiphenylphosphine oxide, the publication is Chemistry Letters (2010), 39(8), 830-831, database is CAplus.

The authors developed Hg(OTf)₂-catalyzed Friedel-Crafts-like cycloisomerization of 7-arylhepta-1,3-dienes to give propenyl-substituted tetrahydronaphthalenes in excellent catalytic turnover under very mild conditions. 1,3-Dienyl sulfonamides and 1,3-dienyl alcs. were also efficiently cyclized to afford heterocyclic compounds

Chemistry Letters published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C14H12N2S, Recommanded Product: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rostami, Hedieh published the artcileOne-Pot Multicomponent Synthesis of Pyrrolo[1,2-a]pyrazines in Water Catalyzed by Fe₃O₄@SiO₂-OSO₃H, SDS of cas: 4230-93-7, the publication is ChemistrySelect (2018), 3(47), 13487-13492, database is CAplus.

An effective and green one-pot multicomponent reaction for the synthesis of pyrrolo[1,2-a]pyrazine derivatives I [R¹ = Ph, 2-thiazolyl, 4-ClC₆H₄, etc.; R² = Me, Et] using Fe₃O₄@SiO₂-OSO₃H as a reusable magnetic nanocatalyst was reported. Compounds I were achieved via reaction among ethylenediamine, dialkyl acetylenedicarboxylates and ¦Â-nitrostyrene derivatives in water as a green solvent with high to excellent yields.

ChemistrySelect published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, SDS of cas: 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia