Tag: M.W=200-250

Singh, Pashupati Prasad published the artcileQuantitative structure activity relationship of inhibitors of glycolic acid oxidase, Application of 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Medicinal Chemistry: An Indian Journal (2006), 2(1), 1-15, database is CAplus.

In order to avoid trial and error method in selecting a suitable drug, QSAR methods have provided a rational basis to the design of enzyme inhibitors. 90 Derivatives of enzyme inhibitors, whose inhibitory potencies in term of PI₅₀ are reported, have been used as study material for QSAR study. These derivatives are divided into five groups: (1) substituted glycolic acids, (2) substituted oxyacetic acids, (3) substituted glyoxylic acids, (4) substituted-3-hydroxy-1H pyrrole-2,5-diones derivatives, (5) 4-heterocyclic substituted 3-hydroxy-1H-pyrrole-2,5-diones derivatives The QSAR study and MLR anal. have been collectively made, because the potency is reported in one unit and the target enzyme glycolic acid oxidase (GAO) is common to all. The study has been made with the help of seven descriptors in different combinations: (1) Heat of formation (¦¤H_f), (2) HOMO energy (3) LUMO energy, (4) Absolute hardness (¦Ç) (5) Mol. weight (MW), (6) Electronegativity (¦Ö) (7) Total energy (TE). This is perhaps for the first time when inhibitory potency has been related with quantum mech. parameters, without any significance to structure of compounds The values of descriptors have been obtained with the help of PC MODEL software using the semiempirical PM3 Hamiltonian. 32 Multi linear regression models using different combinations of descriptors have been developed using the project leader program associated with CAChe software. The predicted activity is close to the observed activity and the correlation coefficient is above 0.80. The best QSAR models are obtained by MLR anal. using the combinations, (i) heat of formation, mol. weight and electronegativity, (ii) mol. wight, total energy and electronegativity.

Medicinal Chemistry: An Indian Journal published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C22H21N3O3S, Application of 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sharma, Abhishek published the artcileUnique versatility of ionic liquids as clean decarboxylation catalyst cum solvent: a metal- and quinoline-free paradigm towards synthesis of indoles, styrenes, stilbenes and arene derivatives under microwave irradiation in aqueous conditions, Application In Synthesis of 16909-09-4, the publication is Advanced Synthesis & Catalysis (2008), 350(18), 2910-2920, database is CAplus.

Ionic liquids have been found to provide a new platform for metal- and quinoline-free decarboxylation of various N-heteroaryl and aryl carboxylic acids under microwave irradiation in aqueous condition. The method was found to possess a wide substrate scope towards the synthesis of various pharmacol. and industrially important aromatic compounds including indoles, styrenes, stilbenes, and nitro- or hydroxyarene derivatives The decarboxylation of indole and ¦Á-phenylcinnamic acids proceeded well without addition of any catalyst in neat 1-hexyl-3-methylimidazolium bromide ([hmim]Br) and 1-methylimidazolium p-toluenesulfonic acid ([Hmim]PTSA), resp., while addition of a mild base like aqueous sodium hydrogen carbonate to [hmim]Br further improved the decarboxylation of hydroxylated cinnamic and aromatic acid substrates. The developed methodol. not only precludes the usage of toxic metal/quinoline and harsh organic bases but also offers several inherent benefits like recyclability of reagent system, reduction in waste and hazards, short reaction time besides ease of product recovery.

Advanced Synthesis & Catalysis published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C5H5F3O2, Application In Synthesis of 16909-09-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Amaravathi, M. published the artcileOxidation of 1-benzyl-3,4-dihydroisoquinolines using active manganese dioxide, Recommanded Product: 2-(3-(Benzyloxy)phenyl)acetic acid, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1983), 22B(12), 1246-7, database is CAplus.

Oxidation of benzyldihydroisoquinolines I [R, R¹, R² = H, H, H; MeO, PhCH₂O, H; H, MeO, H; H, H, NO₂ (II), H, H, Cl] by active MnO₂ gave benzoyldihydroisoquinolines III in yields >80%, except in the case of II which gave the oxidation product in 46% yield.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Recommanded Product: 2-(3-(Benzyloxy)phenyl)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yadav, Sudha published the artcileNonlinear optical single crystals for terahertz generation and detection, SDS of cas: 201157-13-3, the publication is Journal of Nonlinear Optical Physics & Materials (2022), 31(2), 2230001, database is CAplus.

A review. Nonlinear optical (NLO) single crystals with high quality are the pillars for the development of new devices that fulfil the demands of society. Nowadays, NLO single crystals are very attractive for the photonic applications particularly for terahertz (THz) photonics. The reason for their popularity is that these crystals can produce very powerful and ultra wideband THz waves due to their high nonlinear susceptibility. In this review paper, we deal with the challenges and progresses in the evolution of NLO single crystals for THz wave generation and detection. Here, we review the single crystal growth that how and by which method single crystal is grown. We summarize the structures, intermol. and intramol. interactions, their properties and how they generate and detect the THz waves. Widely used single crystals at present are DAST, BNA, OH1, amino acid-based single crystals, etc.

Journal of Nonlinear Optical Physics & Materials published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C13H19Br2ClN2O, SDS of cas: 201157-13-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Krishna published the artcileCu (II) Schiff base complex grafted guar gum: Catalyst for benzophenone derivatives synthesis, Application of Bis(4-fluorophenyl)methane, the publication is Applied Catalysis, A: General (2020), 117529, database is CAplus.

Guar gum based Cu(II) Schiff’s base complex (GG-Cu) has been synthesized and characterized by FT-IR, PXRD, UV-vis, TGA, XPS, FESEM, TEM, EDAX, solid-state NMR, Elemental mapping, CHNS and AAS anal. This moiety has been found to be an efficient heterogeneous catalyst for selective oxidation reactions. Fifteen model reactions have been carried to establish the catalytic behavior of GG-Cu, and five of these yield novel products. The ease of separation of catalyst from the reaction mixture simply by filtration is an added advantage; furthermore the catalyst can be reused up to five times without significant loss of catalytic activity. The overall concept of developing newer, efficient and environmental benign catalysts with ease of separation and recycling ability has been successfully demonstrated. All of the isolated products were fully characterized on the basis of their phys. and spectral data.

Applied Catalysis, A: General published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Application of Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nagase, Masahiro published the artcile4-Position-Selective C-H Perfluoroalkylation and Perfluoroarylation of Six-Membered Heteroaromatic Compounds, Computed Properties of 1206-46-8, the publication is Journal of the American Chemical Society (2016), 138(19), 6103-6106, database is CAplus and MEDLINE.

The first 4-position-selective C-H perfluoroalkylation and perfluoroarylation of six-membered heteroaromatic compounds were achieved using nucleophilic perfluoroalkylation and perfluoroarylation reagents. The regioselectivity was controlled by electrophilically activating the heteroaromatic rings, while sterically hindering the 2-position, with a sterically bulky borane Lewis acid. The reaction proceeded in good yield, even in gram scale, and by a sequential reaction without isolating the intermediates. This reaction could be applied to late-stage trifluoromethylation of a bioactive compound

Journal of the American Chemical Society published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Computed Properties of 1206-46-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Enthaler, Stephan published the artcileLow-Temperature Depolymerization of Polysiloxanes with Iron Catalysis, Recommanded Product: Difluorodiphenylsilane, the publication is ChemSusChem (2014), 7(7), 2030-2036, database is CAplus and MEDLINE.

The easy accessibility and high adjustability of polymers mainly accounts for the great impact of such materials on modern society. Besides this great success, an important matter is the accumulation of large amounts of end-of-life polymers, which are mainly deposited in landfills or converted by thermal recycling or down-cycling to low-quality materials. In contrast to that, the depolymerization of end-of-life polymers to monomers, which can be applied as feedstock in polymerization chem. for high-quality polymers, is only carried out for a small fraction of waste. Polysiloxanes are extensively used in a diverse array of technol. applications. Based on intrinsic properties of polymers, depolymerization is challenging and only a few high-temperature or less environment-friendly processes have been reported. In this regard, we have set up a capable low-temperature protocol for the depolymerization of poly(dimethylsiloxane) in the presence of catalytic amounts of simple iron salts in combination with different depolymerization reagents. The application of benzoyl fluoride, benzoyl chloride/potassium fluoride, or benzoic anhydride/potassium fluoride as depolymerization reagents affords difluorodimethylsilane or 1,3-difluoro-1,1,3,3-tetramethyldisilxanes as products, which are interesting building blocks for the synthesis of new polymers and allow an overall recycling of polysiloxanes.

ChemSusChem published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Recommanded Product: Difluorodiphenylsilane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Brzyska, W. published the artcileThermal decomposition of Y, La and lanthanide benzene-1,2-dioxyacetates in an air atmosphere, Related Products of catalysis-chemistry, the publication is Journal of Thermal Analysis (1996), 46(6), 1687-1695, database is CAplus.

The thermal decomposition of Y, La and lanthanide (from Ce(III) to Lu(III)) benzene-1,2-dioxyacetates Ln₂(C₁₀H₈O₆)₃¡¤nH₂O were studied. The hydrated complexes 1st lose water of crystallization in one or two steps to yield anhydrous compounds or hydrates containing coordination water mols., and then decomposed to the oxides Ln₂O₃, CeO₂, Pr₆O₁₁ and Tb₄O₇ with formation of intermediates, carbonates and oxycarbonates (La, Pr-Eu), oxycarbonates (Y, Tb-Lu) or carbonate (Gd) only. Anhydrous cerium(III) benzene-1,2-dioxyacetate decomposes on heating directly to CeO₂.

Journal of Thermal Analysis published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Brzyska, W. published the artcilePreparation and properties of rare earth element complexes with benzene-1,2-dioxyacetic acid, Quality Control of 5411-14-3, the publication is Polish Journal of Chemistry (1992), 66(4), 587-94, database is CAplus.

M₂L₃.nH₂O (M = Y, La-Nd, Sm-Lu; H₂L = C₆H₄(OCH₂CO₂H)₂–o; n = 7-16) were prepared Their quant. composition, solubility in H₂O at 293 K and molar conductivity of their 5 ¡Á 10^-1 M solutions were determined (solubilities are of the order of 10^-4-10^-3 mol¡¤dm^-3, and conductivities of the order of 10⁷ ¦ÌS). The x-ray diffraction patterns and IR spectra indicated that these complexes are crystalline and that the metal-ligand bond is ionic.

Polish Journal of Chemistry published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Quality Control of 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Brzyska, W. published the artcileProperties and thermal decomposition in air atmosphere of cobalt(II), nickel(II), copper(II) and zinc(II) benzene-1,2-dioxyacetates, SDS of cas: 5411-14-3, the publication is Thermochimica Acta (1993), 223(1-2), 241-9, database is CAplus.

The conditions of formation of Co(II), Ni(II), Cu(II) and Zn(II) benzene-1,2-dioxyacetates were studied and their quant. compositions and solubilities in H₂O at 295 K were determined The IR spectra and x-ray diffractograms for the prepared complexes were recorded and their thermal decompositions in air were studied. During heating, the hydrated complexes MC₁₀H₈O₆.nH₂O lose some crystallization H₂O mols. in 1 or 2 steps, then decompose to the oxides, either directly (Zn) or with intermediate formation of the free metals (Co, Ni and probably Cu).

Thermochimica Acta published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, SDS of cas: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia