Month: December 2022

Adhikari, Birendra Babu published the artcileAllosteric effect of the first lead ion on stepwise extraction of the second lead ion with p-t-butylcalix[5]arene pentacarboxylic acid derivative, COA of Formula: C12H16O3, the publication is Tetrahedron Letters (2010), 51(27), 3481-3485, database is CAplus.

A calix[5]arene-based solvent extraction reagent displaying very high selectivity for lead has been prepared, one mol. of which extracts two lead ions in a stepwise manner. The first Pb²⁺ ion is bound to five phenoxy oxygen atoms inside the calixarene cavity due to which the ligand undergoes conformational freezing in stable cone conformer. This causes pos. allosteric effect for co-extraction of the second lead ion due to the aggregation of functional groups.

Tetrahedron Letters published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, COA of Formula: C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Miyamoto, Katsuhiko published the artcileOptimized terahertz-wave generation using BNA-DFG, Safety of N-Benzyl-2-methyl-4-nitroaniline, the publication is Optics Express (2009), 17(17), 14832-14838, database is CAplus and MEDLINE.

An effective and widely tunable means of producing terahertz (THz) radiation using difference-frequency generation (DFG) in an organic N-benzyl-2-methyl-4-nitroaniline (BNA) crystal was demonstrated by optimizing the pump wavelengths. We calculated the (wideband) refractive index and coherence length mapping of BNA to establish the optimum phase-matching condition of the DFG configuration. To satisfy the phase-matching conditions over the range 0.120 THz, both pump wavelengths were varied from 780 to 950 nm, and the optical wavelength dependency of the THz-wave output was clearly observed We expanded the range of THz-wave generation and increased the power output to ten times that obtained using previous methods.

Optics Express published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C14H14N2O2, Safety of N-Benzyl-2-methyl-4-nitroaniline.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Taniyama, Nobuhiro published the artcileSynthesis of V/Fe/S Clusters Using Vanadium(III) Thiolate Complexes Bearing a Phenoxide-Based Tridentate Ligand, Synthetic Route of 22693-41-0, the publication is Inorganic Chemistry (2014), 53(11), 5438-5446, database is CAplus and MEDLINE.

Vanadium(III) thiolate complexes carrying a phenoxide-based tridentate ligand were prepared from the reactions of V(NMe₂)₄ with the protonated forms of tridentate ligands (H₂(O,P,O) = bis(3,5-di-tert-butyl-2-hydroxyphenyl)phenylphosphine or H₂(O,O,O) = bis(3,5-di-tert-butyl-2-hydroxyphenyl)phenylphosphineoxide) and thiols (HSR; R = mesityl (Mes), 2,4,6-ⁱPr₃C₆H₂ (Tip)). The vanadium-thiolate complexes were subjected to the V/Fe/S cluster synthesis via treatment with an Fe(II) thiolate complex [(TipS)Fe]₂(¦Ì-SDmp)₂ (4, Dmp = 2,6-(mesityl)₂C₆H₃) and elemental sulfur in toluene, giving two new V/Fe/S clusters. One is an edge-bridged double-cubane-type [VFe₃S₄]-[VFe₃S₄] cluster [(O,P,O)VFe₃S₄(SDmp)(HNMe₂)]₂ (5) having face-capping tridentate (O,P,O) ligands on vanadium atoms. The other is a [VFe₃S₄-Fe] cluster [(¦Ì-O,O,O)VFe₃S₄(SDmp)(STip)Fe(¦Ì-SDmp)] (6), the core of which consists of a cubane-type [VFe₃S₄] unit and an external iron atom. The external iron is bound to an SDmp ligand and two oxygen atoms of the tridentate (O,O,O) ligand. Cluster 6 is structurally relevant to the active site of nickel-dependent CO dehydrogenase, and their common structural features include a cubane-type unit with a heterometal, one more iron atom besides the cubane unit, and a bridging ligand between the external iron and the heterometal of the cubane unit.

Inorganic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C6H10O2S, Synthetic Route of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ohta, Shun published the artcileSynthesis and characterization of heteroleptic iron(II) thiolate complexes with weak iron-arene interactions, Synthetic Route of 22693-41-0, the publication is Journal of Organometallic Chemistry (2007), 692(21), 4792-4799, database is CAplus.

Selective preparation and characterization of heteroleptic thiolate complexes of Fe(II) are described. The compounds were synthesized by treatment of Fe bis-amide Fe{N(SiMe₃)₂}₂ (1) with 1 equiv of terphenyl thiols HS(2,6-(aryl)₂C₆H₃) (aryl = mesityl, C₆H₃Me₂-2,6, Ph, p-tol) followed by addition of another equivalent of a different thiol. Five heteroleptic thiolate complexes were synthesized according to this pathway. Addnl., three new homoleptic thiolate complexes were also prepared by addition of 2 equiv of bulky thiols to 1. An amide-thiolate intermediate [{(Me₃Si)₂N}Fe]₂(¦Ì-SDpp)₂ (2; Dpp = 2,6-Ph₂C₆H₃) was isolated from the 1:1 reaction of 1 and HSDpp. The x-ray crystal structures of all new thiolate complexes were determined The compounds crystallize as monomers or dimers, dependent on the substituents. They consist of distorted tetrahedral or trigonal-planar Fe centers with weak interactions to the aromatic rings of the thiolate ligands. The shortest Fe-C(arene) contact is 2.272(2) ?. Stronger Fe-arene interactions appear to induce a more pyramidalized arrangement at the Fe center.

Journal of Organometallic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Synthetic Route of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Komatsuda, Masaaki published the artcileRing-Opening Fluorination of Isoxazoles, Application of 2-Methylbenzoic acid, the publication is Organic Letters (2022), 24(17), 3270-3274, database is CAplus and MEDLINE.

A series of tertiary fluorinated carbonyls I [R¹ = Ph, 2-naphthyl, 2-thienyl, etc.; R² = Me, nBu, (CH₂)₂Ph, etc.] was developed via ring-opening fluorination of isoxazoles by using an electrophilic fluorinating agent (Selectfluor) followed by deprotonation. This method featured mild reaction conditions, good functional group tolerance and a simple exptl. procedure. Diverse transformations of the resulting ¦Á-fluorocyanoketones were also demonstrated, furnished a variety of fluorinated compounds

Organic Letters published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Application of 2-Methylbenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nokami, Toshiki published the artcileIterative Molecular Assembly Based on the Cation-Pool Method. Convergent Synthesis of Dendritic Molecules, Recommanded Product: Bis(4-fluorophenyl)methane, the publication is Journal of the American Chemical Society (2008), 130(33), 10864-10865, database is CAplus and MEDLINE.

An iterative method for mol. assembly has been developed based on the cation-pool method using (trimethylsilyl)diphenylmethane as a building block. The silyl group works as both an activating group of the benzene ring in the Friedel-Crafts type reaction and an electroauxiliary in the subsequent low temperature anodic oxidation to generate dendritic diarylcarbenium ions, which were well characterized by low-temperature NMR spectroscopy. The convergent synthesis of dendritic mols. has been achieved by repeating the sequence.

Journal of the American Chemical Society published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Recommanded Product: Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Mihara, Akane published the artcileAssociation of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community, Category: catalysis-chemistry, the publication is Scientific Reports (2022), 12(1), 12427, database is CAplus and MEDLINE.

Abstract: We examined the association of serum s-adenosylmethionine (SAM), s-adenosylhomocysteine (SAH) (methionine metabolites), and their ratio on the risk of dementia and death in a community-dwelling population of older Japanese individuals. 1371 residents of Hisayama, Japan, aged 65 years or older and without dementia, were followed for a median of 10.2 years (2007-2017). We divided serum SAM, SAH, and SAM/SAH ratio into quartiles. Cox proportional hazards models were used to estimate the hazard ratios (HRs) and their 95% confidence intervals (CIs) of serum SAM, SAH, and SAM/SAH ratio levels on the risk of a composite outcome of all-cause dementia or death, and each outcome. During the follow-up, 635 participants developed all-cause dementia and/or died, of which 379 participants developed dementia and 394 deaths occurred. The multivariable-adjusted HRs of the composite outcome decreased significantly with increasing serum SAM levels (P for trend = 0.01), while they increased significantly with higher serum SAH levels (P for trend = 0.03). Higher serum SAM/SAH ratio levels were significantly associated with a lower risk of the composite outcome (P for trend = 0.002), as well as with lower risk of each outcome. Our findings suggest that the balance of methionine metabolites may closely associate with the risk of dementia and death.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lee, Sang Ju published the artcileSimple and highly efficient synthesis of 3′-deoxy-3′-[¹⁸F]fluorothymidine using nucleophilic fluorination catalyzed by protic solvent, Formula: C17H37NO3, the publication is European Journal of Nuclear Medicine and Molecular Imaging (2007), 34(9), 1406-1409, database is CAplus and MEDLINE.

The aim of this study was to develop a method of radiochem. synthesis of 3′-deoxy-3′-[¹⁸F]fluorothymidine ([¹⁸F]FLT) with an improved radiochem. yield using nucleophilic substitution catalyzed by protic solvent. We introduced t-BuOH as a new reaction solvent for nucleophilic [¹⁸F]fluorination with [¹⁸F]fluoride using (5′-O-DMTr-2′-deoxy-3′-O-furanosyl-¦Â-D-threo-pentofuranosyl)-3-N-BOC-thymine to synthesize [¹⁸F]FLT. [¹⁸F]F^– was eluted with (1) tetrabutylammonium bicarbonate (TBAHCO₃), (2) Cs₂CO₃ and kryptofix 2.2.2 (K₂₂₂) after trapping of [¹⁸F]F^– on an ion exchange cartridge, or (3) addition of tetrabutylammonium hydroxide (TBAOH) and [¹⁸F]F^– to the reactor without trapping [¹⁸F]F^– on an ion exchange cartridge. We optimized [¹⁸F]fluorination conditions with t-butanol and then applied them to automatic synthesis using com. available radiochem. modules (TracerLab MX, GE Healthcare). We achieved a high radiochem. yield of 85.3 ¡À 3.5% by radio-TLC with TBAHCO₃ as an elution solvent and 20 mg of precursor at 100¡ãC (n = 4). With the same labeling conditions, use of Cs₂CO₃ and K₂₂₂ with t-BuOH and TBAOH with t-BuOH generated radiochem. yields of 57.1 ¡À 22.5% and 55.0 ¡À 18.8% by radio-TLC, resp. (n = 3 for each condition). Automated synthesis with TBAHCO₃ and 20 mg of precursor at 120¡ãC for 10 min of [¹⁸F]fluorination led to radiochem. yields of 60.2 ¡À 5.2% after HPLC purification with an MX module (n = 10). Synthesized [¹⁸F]FLT was stable for 6 h. [¹⁸F]FLT was synthesized with a significantly improved radiochem. yield by nucleophilic substitution catalyzed by protic solvent with mild reaction conditions and a short preparation time.

European Journal of Nuclear Medicine and Molecular Imaging published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Formula: C17H37NO3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Adeyemi, Kazeem D. published the artcileDietary supplementation of Allium cepa skin alters intramuscular fat, muscle cholesterol, and fatty acids in rabbits, HPLC of Formula: 6217-54-5, the publication is Journal of the Science of Food and Agriculture (2022), 102(9), 3683-3692, database is CAplus and MEDLINE.

The high polyunsaturated fatty acids content of rabbit meat predisposes it to oxidative deterioration, which often results in reduced product quality and shelf life. This fact highlights the need to improve the antioxidant status of rabbit meat. This study investigated the effects of dietary supplementation of Allium cepa skin (ACS) on growth, carcass, i.m. fat, muscle fatty acids, cholesterol content, meat quality, antioxidant status, and sensory attributes of hind leg muscle of rabbits. Sixty-three, 28-day-old, male New Zealand rabbits (654 ¡À 25 g) were randomly allocated into 21 pens of three rabbits. The pens were randomly assigned to one of three dietary treatments – ACS-0: basal diet (BD) only; ACS-25: BD + 25 g kg^-1 ACS; and ACS-50: BD + 50 g kg^-1 ACS – for 56 days and then euthanized. Dietary ACS did not affect growth performance and retail cuts of rabbits. Muscle cholesterol was lower (P < 0.05) in ACS-supplemented rabbits than in controls. Dietary ACS lowered (P < 0.05) dissectible fat, i.m. fat content, C14:0, C16:0, C18:0, C18:2n-6, and C20:4n-6 levels and enhanced (P < 0.05) C18:3n-3, C20:5n-3, C22:6n-3, and C22:5n-3 concentration Dietary ACS increased muscle catalase activity in rabbits. Sensory qualities, malondialdehyde and carbonyl contents, and physicochem. attributes of hind leg muscle of rabbits after chill storage were not influenced by dietary ACS supplementation. Supplementation with 50 g kg-1 ACS reduced i.m. fat and cholesterol content and improved muscle n-3 fatty acids without impairing the physicochem. and sensory properties of rabbit meat. 2021 Society of Chem. Industry.

Journal of the Science of Food and Agriculture published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, HPLC of Formula: 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kameo, Kazuya published the artcileStudies on antirheumatic agents: 3-benzoylpropionic acid derivatives, Recommanded Product: 2-Methylene-4-oxo-4-phenylbutanoic acid, the publication is Chemical & Pharmaceutical Bulletin (1988), 36(6), 2050-60, database is CAplus and MEDLINE.

As part of the search for new antirheumatic agents, three types of 3-benzoylpropionic acid derivatives, e.g. RCOCH₂CH(SR¹)CO₂R², RCOCH₂CH(CH₂SR¹)CO₂R², and RCOCH(CH₂SR¹)CH₂CO₂R² (R = Ph, substituted phenyl; R¹ = Ac, Et, EtCO, Bz; R² = H, Et, Me, CH₂Ph), having a mercapto moiety in their structures were prepared and tested for suppressing activity on adjuvant arthritis in Sprague-Dawley rats. A structure-activity relationship study showed that substitution on the Ph ring contributed to the activity and the most favorable substituent was different in each type of derivative

Chemical & Pharmaceutical Bulletin published new progress about 15732-75-9. 15732-75-9 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ketone, name is 2-Methylene-4-oxo-4-phenylbutanoic acid, and the molecular formula is C11H10O3, Recommanded Product: 2-Methylene-4-oxo-4-phenylbutanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia