Month: December 2022

Nayak, Biswajit published the artcileTerminal Substituent Induced Differential Anion Coordination and Self-Assembly: Case Study of Flexible Linear Bis-Urea Receptors, Recommanded Product: Tetraethylammonium hydrogencarbonate, the publication is Crystal Growth & Design (2019), 19(4), 2298-2307, database is CAplus.

For a comprehensive anal. of host-guest binding propensity in their neutral form, three linear flexible bis-urea receptors (L₁-L₃) with different terminal substituents have been synthesized. It has been established that, with the existence of electron-withdrawing or ¦Ð-acidic Ph substituents, they act as a possible system that can proficiently coordinate with anions of diverse dimensions constantly initiated by the size of the countercations. The 3,5-bis(trifluoromethyl)phenyl-derived isomer (L₁) can readily form cooperative neutral self-assemblies irresp. of the size of the monovalent halides (viz. chloride, bromide, and iodide anions) and noncooperative neutral self-assemblies with planar divalent carbonate anion. The meta isomer L₂ captures spherical halides, i.e. chloride and bromide, in an isostructural way, forming a 1:2 host-guest assembly, whereas the isomeric para receptor L₃ shows cooperative binding with chloride anions, having coordination number 3. However, due to the greater flexibility and lesser hydrophobicity of receptor L₂ and L₃ in comparison to receptor L₁, successful crystallization of any oxyanion complexes through the meta and para isomers was not successful.

Crystal Growth & Design published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C9H21NO3, Recommanded Product: Tetraethylammonium hydrogencarbonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Datta, Sanchita published the artcileSynthesis, anticancer activity, SAR and binding mode of interaction studies of substituted pentanoic acids: part II, Name: 4-Nitrophenylacetic acid, the publication is Future Medicinal Chemistry (2022), 14(1), 17-34, database is CAplus and MEDLINE.

Here, 13 new compounds were synthesized and characterized. Along with these new compounds, 16 previously reported phenyl/naphthylacetyl pentanoic acid derivatives were biol. evaluated. Compounds I and II showed good cytotoxicity against leukemia cell line Jurkat E6.1. The mechanisms of cytotoxicity of these compounds were confirmed by DNA deformation assay and reactive oxygen species assay. MMP-2 and HDAC8 expression assays suggested the dual inhibiting property of these two compounds These findings were supported by results of mol. docking studies. In silico pharmacokinetic properties showed compounds I and II have high gastrointestinal absorption. This study highlights the action of phenyl/naphthylacetyl pentanoic acid derivatives as anticancer agents.

Future Medicinal Chemistry published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C8H7NO4, Name: 4-Nitrophenylacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

El-Wekil, Mohamed M. published the artcileAn innovative dual recognition aptasensor for specific detection of Staphylococcus aureus based on gold/iron oxide binary hybrid, Quality Control of 63-68-3, the publication is Scientific Reports (2022), 12(1), 12502, database is CAplus and MEDLINE.

Pathogenic bacteria cause disease outbreaks and threaten human health, prompting the research on advanced detection assays. Herein, we developed a selective mol. imprinted aptasensor for sensitive and prompt quantitation of Staphylococcus aureus (S. aureus) bacteria. The aptasensor was constructed by immobilization of aptamer on gold nanoparticles modified magnetic nanoparticles (apt-AuNPs@ Fe₃O₄). A functional monomer (o-phenylenediamine, o-phen) was electro-polymerized on the surface of the as-synthesized nanocomposite in the presence of a template (S. aureus). After removing S. aureus, the formed imprinted sites were available to extract pathogenic bacteria from complicated matrixes. The surface morphol. of the as-fabricated nanocomposites was characterized using different spectroscopic and electrochem. methods. Moreover, we thoroughly evaluated factors affecting the synthesis and determination procedures. The mol. imprinted aptasensor exhibited a wide linear range of 10¹-10⁷ CFU mL^-1 with a Limit of Detection, LOD (signal to noise = 3) of 1 CFU mL^-1. The aptasensor detected S. aureus in milk, conduit water, and apple juice samples with good recoveries % and satisfactory relative standard deviations (RSDs %) values.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Quality Control of 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Trska, Petr published the artcileCarbon-13 chemical shifts of aza- and triazaadamantane derivatives, Name: 1,3,5-Triazaadamantan-7-amine, the publication is Organic Magnetic Resonance (1984), 22(5), 352-5, database is CAplus.

¹³C NMR chem. shifts for 1-azaadamantane, twelve N-substituted 1-azaadamantanes, 1,3,5-triazaadamantane (I) and for nine derivatives of I were recorded.

Organic Magnetic Resonance published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H6Cl2O, Name: 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Trska, Petr published the artcileSubstituent effects on the carbon-13 NMR chemical shifts of aza- and triazaadamantanes, Application of 1,3,5-Triazaadamantan-7-amine, the publication is Sbornik Vysoke Skoly Chemicko-Technologicke v Praze, H: Analyticka Chemie (1984), 29-40, database is CAplus.

¹³C NMR chem. shifts were studied for 13 N-substituted 1-aza- and 11 1,3,5-triazaadamantane derivatives The effects of substitution at the N for the former and at C-7 for the latter compounds were examined The ¦Á-C atoms in azaadamantanes were influenced in the same manner as the ¦Â-carbons in 1-substituted adamantanes. Similar results were obtained for 7-substituted triazaadamantanes. The substituent-chem.-shift (SCS) contributions for the 1-azaadamantane derivatives did not correlate simply with the electron densities obtained by the EHT method. Factor anal. was applied to 9 1-azaadamantanes, and the charges at the ¦Á, ¦Â and ¦Ã C atoms were established to be the decisive factors. Based on these data, the chem. shifts for a compound in this series were calculated with reasonable accuracy using the SCS matrix of the remaining 8 compounds

Sbornik Vysoke Skoly Chemicko-Technologicke v Praze, H: Analyticka Chemie published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C5H11NO2S, Application of 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Beudert, Matthias published the artcileMerging bioresponsive release of insulin-like growth factor I with 3D printable thermogelling hydrogels, Related Products of catalysis-chemistry, the publication is Journal of Controlled Release (2022), 115-126, database is CAplus and MEDLINE.

3D Printing of biomaterials enables spatial control of drug incorporation during automated manufacturing This study links bioresponsive release of the anabolic biol., insulin-like growth factor-I (IGF-I) in response to matrix metalloproteinases (MMP) to 3D printing using the block copolymer of poly(2-methyl-2-oxazoline) and thermoresponsive poly(2-n-propyl-2-oxazine) (POx-b-POzi). For that, a chemo-enzymic synthesis was deployed, ligating IGF-I enzymically to a protease sensitive linker (PSL), which was conjugated to a POx-b-POzi copolymer. The product was blended with the plain thermogelling POx-b-POzi hydrogel. MMP exposure of the resulting hydrogel triggered bioactive IGF-I release. The bioresponsive IGF-I containing POx-b-POzi hydrogel system was further detailed for shape control and localized incorporation of IGF-I via extrusion 3D printing for future applications in biomedicine and biofabrication.

Journal of Controlled Release published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kohga, Makoto published the artcileEffects of addition of surfactants on viscosity of uncured ammonium perchlorate/hydroxyl-terminated polybutadiene propellant, Formula: C14H31NO2, the publication is Kayaku Gakkaishi (1998), 59(4), 167-173, database is CAplus.

For the preparation of ammonium perchlorate (AP)/hydroxyl-terminated polybutadiene (HTPB) composite propellant, the lower viscosity of uncured propellant during mixing and casting is desirable. In this study, the effects ot the addition of 11 kinds of surfactants on the viscosity of an uncured propellant are investigated. Sodium lauryl sulfate is the most effective to decrease the viscosity of the AP/HTPB mixture The apparent viscosity of the AP/HTPB mixture with sodium lauryl sulfate can be made 30% lower than that of the AP/HTPB mixture alone. The optimum added amount of sodium lauryl sulfate is 0.005 wt% to HTPB, in order to obtain the sufficient effect of decreasing the viscosity of AP/HTPB mixture The apparent viscosity of AP/HTPB mixture can be decreased by the improvement of the wettability between AP and HTPB prepolymer. The addition of sodium lauryl sulfate is effective to decrease the apparent viscosity of uncured propellant and to delay the pot life.

Kayaku Gakkaishi published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Formula: C14H31NO2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tang, Jie published the artcileBranched Arylalkenes from Cinnamates: Selectivity Inversion in Heck Reactions by Carboxylates as Deciduous Directing Groups, Name: (E)-3-(3-Nitrophenyl)acrylic acid, the publication is Angewandte Chemie, International Edition (2016), 55(37), 11296-11299, database is CAplus and MEDLINE.

A decarboxylative Mizoroki-Heck coupling of aryl halides with cinnamic acids has been developed in which the carboxylate group directs the arylation into its ¦Â-position before being tracelessly removed through protodecarboxylation. In the presence of a copper/palladium catalyst, both electron-rich and electron-deficient aryl bromides and chlorides bearing numerous functionalities were successfully coupled with broadly available cinnamates, with selective formation of 1,1-disubstituted alkenes. This reaction concept, in which the carboxylate acts as a deciduous directing group, ideally complements traditional 1,2-selective Heck reactions of styrenes.

Angewandte Chemie, International Edition published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C14H10N2O, Name: (E)-3-(3-Nitrophenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

McCoy, Michael J. published the artcileDetection of angiotensin II binding to single adrenal zona glomerulosa cells by confocal Raman microspectroscopy, Application of 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, the publication is Proceedings of SPIE-The International Society for Optical Engineering (1999), 195-203, database is CAplus.

We developed a confocal Raman microspectroscopic technique to study ligand-receptor bindings in single cells using Raman-labeled ligands and surface-enhanced Raman scattering (SERS). The adrenal zona glomerulosa (ZG) cells were used as a model in this study. ZG cells have a high d. of angiotensin II (AII) receptors on the cellular membrane. There are two identified subtypes of AII receptors,namely AT1 and AT2 receptors. AII is a peptidic hormone, which upon binding to its receptors, stimulates the release of aldosterone from ZG cells. The cellular localization of these receptors subtypes was detected in single ZG cells by using immunocomplexation of receptors with specific antibodies and confocal Raman microspectroscopy. In the binding study, we used biotin-labeled AII to bind to its receptors in ZG cells. Then, avidin and Raman-labeled AII. The binding was measure directly on the single ZG cells. The results showed that the binding was displaced with unlabeled AII and specific AII antagonists. This is a rapid and sensitive technique for detection of cellular ligand bindings as well as antagonists screening in drug discovery.

Proceedings of SPIE-The International Society for Optical Engineering published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Application of 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Myers, H. P. published the artcileThe transmission of infrared radiation through sintered uranium dioxide, Computed Properties of 1821-27-8, the publication is New Nucl. Mater. Including Non-Metal. Fuels, Proc. Conf., Prague (1963), 323-8, discussion, 328-9, database is CAplus.

The infrared absorption spectra of sintered UO₂ samples were measured at 0.86-15 ¦Ì. The contribution that transmitted radiant energy can make to the heat-transfer properties of UO₂ was calculated It is postulated that in unirradiated UO₂ radiant energy transfer can only be significant above 1500¡ãK., at which temperature the contribution is approx. 10% of the lattice conductivity; at 3000¡ãK., it equals the lattice conductivity It is probably the maximum contribution since reflection losses, temperature effects on the absorption spectrum, and impurities such as fission products will reduce the transmittance of irradiated UO₂.

New Nucl. Mater. Including Non-Metal. Fuels, Proc. Conf., Prague published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C12H9N3O4, Computed Properties of 1821-27-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia