Month: December 2022

Tamoradi, Taiebeh published the artcileFe₃O₄-AMPD-Pd: A novel and efficient magnetic nanocatalyst for synthesis of sulfides and oxidation reactions, Application of 2,2′-Dithiodibenzoic acid, the publication is Polyhedron (2018), 104-109, database is CAplus.

A novel magnetic nanoparticle was synthesized with effective catalytic properties and recyclable ability. This heterogeneous nanocatalyst was identified using Fourier transform IR, scanning electron microscopies, X-ray diffraction, vibrating sample magnetometer, inductively coupled plasma at. emission spectroscopy and thermogravimetric anal. methods. The nanocatalyst was used for the synthesis of the one-pot C-S coupling synthesis of sulfide in the presence of KOH, S₈ as the sulfur source in DMSO as the solvent at 100 ¡ãC. Also, the oxidation of sulfides to sulfoxides and oxidative coupling of thiols to disulfides in the presence of the catalyst was tested. The catalyst has unique properties such as ability of magnetic separation from the reaction, high repeatability, and high thermal and chem. stability.

Polyhedron published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C7H10O4, Application of 2,2′-Dithiodibenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Groendyke, Brian J. published the artcileFenton-Inspired C-H Functionalization: Peroxide-Directed C-H Thioetherification, HPLC of Formula: 119-80-2, the publication is Journal of Organic Chemistry (2019), 84(20), 13073-13091, database is CAplus and MEDLINE.

Substoichiometric iron mediates the thioetherification of unactivated aliphatic C-H bonds directed by resident silylperoxides. Upon exposure to a catalytic amount of iron(II) triflate, TIPS-protected peroxides bearing primary, secondary, and tertiary C-H sites undergo chemoselective thioetherification of remote C-H bonds with diaryl disulfides. The reaction demonstrates a broad substrate scope and functional group tolerance without the use of any noble metal additives. Mechanistic experiments suggest that the reaction proceeds through 1,5-H atom abstraction by a hydroxyl radical generated with iron.

Journal of Organic Chemistry published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, HPLC of Formula: 119-80-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Golchoubian, Hamid published the artcileHalochromism, ionochromism, solvatochromism and density functional study of a synthesized copper(II) complex containing hemilabile amide derivative ligand, Formula: C16H20N2, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2015), 913-924, database is CAplus and MEDLINE.

This study investigates chromotropism of newly synthesized 3,3′-(ethane-1,2-diylbis(benzylazanediyl))dipropanamide copper(II) perchlorate complex. The compound was structurally characterized by physico-chem. and spectroscopic methods. X-ray crystallog. of the complex showed that the copper atom achieved a distorted square pyramidal environment through coordination of two amine N atoms and two O atoms of the amide moieties. The pH effect on the visible absorption spectrum of the complex was studied which functions as pH-induced “off-on-off” switches through protonation and deprotonation of amide moieties along with the Cu-O to Cu-N bond rearrangement at room temperature The complex was also observed to show solvatochromism and ionochromism. The distinct solution color changes mainly associated with hemilability of the amide groups. The solvatochromism of the complex was investigated with different solvent parameter models using stepwise multiple linear regression method. The results suggested that the basicity power of the solvent has a dominant contribution to the shift of the d-d absorption band of the complex. D. functional theory, DFT calculations were performed in order to study the electronic structure of the complex, the relative stabilities of the Cu-N/Cu-O isomers, and to understand the nature of the halochromism processes taking place. DFT computational results buttressed the exptl. observations indicating that in the natural pH (5.8) the Cu-O isomer is more stable than its linkage isomer and conversely in alk. aqueous solution

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Formula: C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xu, Xiaokai published the artcileRed, green and blue aggregation-induced emissive carbon dots, Application In Synthesis of 119-80-2, the publication is Chinese Chemical Letters (2021), 32(12), 3927-3930, database is CAplus.

As one of the most promising fluorescent nanomaterials, carbon dots (CDs) have been extensively studied for their fluorescent properties in solution However, research on the synthesis of multicolor solid-state fluorescence (SSF) CDs (from blue to red) is rarely reported. Herein, we used o-phenylenediamine, m-phenylenediamine and p-phenylenediamine with dithiosalicylic acid (DTSA) in the solvothermal reaction using acetic acid as a solvent to obtain aggregation-induced emissive (AIE) CDs of red (620 nm), green (520 nm), and blue (478 nm), resp. XPS spectra and TEM image show that with the red-shift of luminescence, the particle size and content of C = O of the CDs gradually increases. Finally, based on the non-matrix solid-state multicolor luminescence characteristics of CDs, the application of white light LED devices is realized. Besides, based on the fat-soluble properties of CDs, fingerprint detection applications are realized.

Chinese Chemical Letters published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C12H14IN, Application In Synthesis of 119-80-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xu, Xiaokai published the artcileConstruction of Carbon Dots with Color-Tunable Aggregation-Induced Emission by Nitrogen-Induced Intramolecular Charge Transfer, Quality Control of 119-80-2, the publication is Advanced Materials (Weinheim, Germany) (2021), 33(49), 2104872, database is CAplus and MEDLINE.

As one of the most promising fluorescent nanomaterials, the fluorescence of carbon dots (CDs) in solution is extensively studied. Nevertheless, the synthesis of multicolor solid-state fluorescence (SSF) CDs is rarely reported. Herein, CDs with multicolor aggregation-induced emission are prepared using amine mols., all of them exhibiting dual fluorescence emission at 480 nm (Em-1) and 580-620 nm (Em-2), which is related to the S-S bonds of dithiosalicylic acid and the conjugated structure attached to C=O/C=N bonds, resp. As a strong electron-withdrawing group, the increase of C=N content makes dual-fluorescent groups on the surface of CDs produce push and pull electrons, which determines intramol. charge transfer (ICT) between the double emission. With the increase in C=N content from 35.6% to 58.4%, the ICT efficiency increases from 8.71% to 45.94%, changing the fluorescence of CDs from green to red. The increase of ICT efficiency causes fluorescence quantum yield enhancement by nearly five times and red shift of the fluorescence peak. Finally, based on the multicolor luminescence properties induced by the aggregation of CDs, pattern encryption and white-LED devices are realized. Based on the fat solubility and strong UV absorption characteristics of CDs, fingerprint detection and leaf anti-UV hazards are applied.

Advanced Materials (Weinheim, Germany) published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C12H14IN, Quality Control of 119-80-2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Su, Junqi published the artcileGeneration of oxyphosphonium ions by photoredox/cobaloxime catalysis for scalable amide and peptide synthesis in batch and continuous-flow, HPLC of Formula: 118-90-1, the publication is Angewandte Chemie, International Edition (2022), 61(5), e202112668, database is CAplus and MEDLINE.

Phosphine-mediated deoxygenative nucleophilic substitutions, such as the Mitsunobu reaction, are of great importance in organic synthesis. However, the conventional protocols require stoichiometric oxidants to trigger the formation of the oxyphosphonium intermediates for the subsequent nucleophilic additions Through dual catalysis of photoredox and cobaloxime, we realized a radical strategy for the catalytic formation of acyloxyphosphonium ions that enables direct amidation. The deoxygenative protocol exhibits a broad scope and has been used in the late-stage amidation of drug mols. In addition to batch reactions, a continuous-flow reactor was developed, enabling rapid peptide synthesis on gram scale. The successful assembly of a tetrapeptide on the solid support further demonstrated the versatility of this photocatalytic system. Moreover, exptl. and computational studies are consistent with the hypothesis of acyloxyphosphonium ions being formed as the key intermediates.

Angewandte Chemie, International Edition published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C4H6O3, HPLC of Formula: 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Mido, Yoshiyuki published the artcileInfrared and Raman spectra of N-methyl-N’-n-alkylthioureas, Synthetic Route of 6972-05-0, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (1988), 44A(4), 445-7, database is CAplus.

The IR and Raman spectra of solid CH₃NHCSNH(CH₂)_nCH₃ (n = 0-15) (MTUR’) and CH₃NDCSND(CH₂)_nCH₃ (n = 0-9) were examined The vibrational properties of N,N‘-disubstituted thioureas were studied on the basis of the spectral comparison among the series of compounds, the waveno. shift by N-deuteration, and a comparison with the vibrational properties of the urea analog. From the anal. of interactions between end-group vibrations and CH₂ band progression modes, MTUR’ mols. are in a skeletal planar structure with an extended n-alkyl chain.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Synthetic Route of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shamsipur, Mojtaba published the artcileHighly selective and sensitive membrane sensors for copper(II) ion based on a new benzo-substituted macrocyclic diamide 5,6,7,8,9,10-hexahydro-2H-1,13,4,7,10-benzodioxatriazacyclopentadecine-3,11(4H,12H)-dione, Application of 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Electroanalysis (2007), 19(5), 587-596, database is CAplus.

Novel PVC membrane (PME) and coated graphite (CGE) Cu²⁺-selective electrodes based on 5,6,7,8,9,10-hexahydro-2H-1,13,4,7,10-benzodioxatriazacyclopentadecine-3, 11(4H,12H)-dione were prepared The electrodes reveal a Nernstian behavior over wide Cu²⁺ ion concentration ranges (1.0 ¡Á 10^-7 – 1.0 ¡Á 10^-1 M for PME and 1.0 ¡Á 10^-8 – 1.0 ¡Á 10^-1 M for CGE) with very low limits of detection (7.8 ¡Á 10^-8 M for PME and 9.1 ¡Á 10^-9 M for CGE). The potentiometric responses are independent of the pH of the test solutions in the pH range 2.7-6.2. The proposed electrodes possess very good selectivities for Cu²⁺ over a wide variety of the cations including alkali, alk. earth, transitions and heavy metal ions. The practical utility of the proposed electrodes were demonstrated by their use in the study of interactions between Cu ions and human growth hormone (hGH) in biol. systems, potentiometric titration of Cu with EDTA and determination of Cu content of a sheep blood serum sample and some other real samples.

Electroanalysis published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C8H5F3N4, Application of 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tsukiyama, Junko published the artcileEffects of over-the-counter artificial tears and eye wash solutions on multifocal soft contact lenses, Synthetic Route of 194491-31-1, the publication is Nippon Kontakuto Renzu Gakkaishi (2020), 62(3), 108-112, database is CAplus.

The author evaluated the effects of 3 over-the-counter (OTC) artificial tears/eyewash solutions on 6 types of 1-day disposable multifocal soft contact lenses (SCLs). One each of the etafilcon A, nelfilcon A, omafilcon A, SEED 1-day pure, delefilcon A, and nesofilcon A SCLs </div> were immersed in each of the 3 artificial tears/ eyewash solutions: Soft Santear (S), My tear CL (M), and Well Wash Eye (W). After the SCL had been immersed for 5 h in the solution, the size of the SCL was evaluated using Image J. The Etafilcon A SCL had expanded during immersion in S and M and especially during immersion in W (by 14.2%). The nelfilcon A SCL had shrunk during immersion in S and M and especially during immersion in W (by 11.8%). Although exposure of the SCLs to S, M, and W solutions during this experiment was severe compared to exposure during ordinary use of these solutions, the results of the experiment show that there is interaction between these SCLs and OTC artificial tears/eyewash solutions Therefore, SCL prescribers should be careful to evaluate the use of these OTC solutions by their patients.</div>.

Nippon Kontakuto Renzu Gakkaishi published new progress about 194491-31-1. 194491-31-1 belongs to catalysis-chemistry, auxiliary class Carboxylic Acid Salts,Amine,Aliphatic hydrocarbon chain, name is Sodium 2,2′,2”,2”’-(ethane-1,2-diylbis(azanetriyl))tetraacetate xhydrate, and the molecular formula is C3H7NO2, Synthetic Route of 194491-31-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Miyakoshi, Hitoshi published the artcile1,2,3-Triazole-Containing Uracil Derivatives with Excellent Pharmacokinetics as a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors, Recommanded Product: 2-(3-(Benzyloxy)phenyl)acetic acid, the publication is Journal of Medicinal Chemistry (2012), 55(14), 6427-6437, database is CAplus and MEDLINE.

Deoxyuridine triphosphatase (dUTPase) has emerged as a potential target for drug development as a 5-fluorouracil-based combination chemotherapy. The design and synthesis of a novel class of human dUTPase inhibitors, 1,2,3-triazole-containing uracil derivatives, is described. Compound I, which possesses 1,5-disubstituted 1,2,3-triazole moiety that mimics the amide bond of tert-amide-containing inhibitor II locked in a cis conformation showed potent inhibitory activity, and its structure-activity relationship studies led us to the discovery of highly potent inhibitors III and IV (IC₅₀ = ?0.029 ¦ÌM). These derivatives dramatically enhanced the growth inhibition activity of 5-fluoro-2′-deoxyuridine against HeLa S3 cells in vitro (EC₅₀ = ?0.05 ¦ÌM). In addition, compound IV exhibited a markedly improved pharmacokinetic profile as a result of the introduction of a benzylic hydroxy group and significantly enhanced the antitumor activity of 5-fluorouracil against human breast cancer MX-1 xenograft model in mice. These data indicate that IV is a promising candidate for combination cancer chemotherapies with TS inhibitors.

Journal of Medicinal Chemistry published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Recommanded Product: 2-(3-(Benzyloxy)phenyl)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia