Catalysis-chemistry

Abu-Hashem, Ameen Ali published the artcileSynthesis of new pyrazoles, oxadiazoles, triazoles, pyrrolotriazines, and pyrrolotriazepines as potential cytotoxic agents, Formula: C10H10O3, the publication is Journal of Heterocyclic Chemistry (2021), 58(3), 805-821, database is CAplus.

The 4-oxo-4-phenylbutanehydrazide reacted with many active methylene reagents such as acetylacetone, diethylmalonate, ethylacetoacetate, ethylcyanoacetate, benzoyl-acetonitrile, and malononitrile under neat conditions to afford the corresponding pyrazoles e.g., I, also, treatment of 4-oxo-4-phenylbutanehydrazide with electrophilic reagents as triethylorthoformate, dimethylformamide-dimethylacetal, acetic anhydride, and carbon disulfide to give 1,3,4-oxadiazoles e.g., II and N’-acetyl-4-oxo-4-phenylbutanehydrazide. Reaction of 4-oxo-4-phenylbutanehydrazide with potassium thiocyanate gave 1-phenyl-3-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)propan-1-one. Similarly, treatment of 4-oxo-4-phenylbutanehydrazide with chloroacetamide gave 3-(3-oxo-3-phenylpropyl)-1,6-dihydro-1,2,4-triazin-5(2H)-one. The 6-phenyl-3,4-dihydropyrrolo[1,2-b][1,2,4]triazin-2(8H)-one was obtained by cyclization of 3-(3-oxo-3-phenylpropyl)-1,6-dihydro-1,2,4-triazin-5(2H)-one. Also, 4-oxo-4-phenylbutanehydrazide was utilized as a starting material for the synthesis of new Schiff bases as N’-(4-sub-benzylidene)-phenylbutane-hydrazides C₆H₅C(O)(CH₂)₂C(O)NHN=CHAr (Ar = Ph, 4-chlorophenyl, 4-methoxyphenyl), which are used as an initiative to prepare new compounds such as 1,2,4-triazepinones III, pyrrolotriazepinones IV, 1,2,4-triazines V, and pyrrolotriazines VI by reaction of N’-(4-sub-benzylidene)-phenylbutane-hydrazides with each chloroacetamide or formamide. The prepared compounds were tested for their in vitro antitumor activities. The compounds III, IVand VI displayed activity against several types of cancer cell lines.

Journal of Heterocyclic Chemistry published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C10H10O3, Formula: C10H10O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Abraham, Sharon Achamma Abraham published the artcileStructures of cation doped polyacenes and its binding energies across polyacene surface, COA of Formula: C24H12, the publication is Materials Today: Proceedings (2022), 57(Part_4), 1858-1864, database is CAplus.

The Binding energies of cation-¦Ð complexes are calculated computationally using DFT method and the B3LYP functional. The binding energies in kcal/mol using B3LYP functional and 6-31 + G(d,p) basis set in Gaussian09 has provided a source to design one-dimensional materials and to study hopping of charges in one-dimensional materials. The Mulliken charges and ¦¤E in kcal/mol with bsse corrections are confirmed using B3LYP functional and 6-31 + G(d,p) basis set in Gaussian09. Above benzene ring, a cation is located at a distance of 2.5 ? above plane of mol. and binding energy (¦¤E)is calculated using B3LYP functional and 6-31 + G(d,p) basis set, which shows difference between energy of [benzene….Metal ion complex] and sum of energy of [benzene] and [cation M⁺]. Binding energies of cation-¦Ð complexes on polyacenes are determined and studied hopping dynamics. Binding energies as well as hopping energies for cations to polyaromatic hydrocarbons follows the order Li⁺>Na⁺>K⁺. Binding energies (¦¤E) decreases with size of cation(M+) as Li⁺>Na⁺>K⁺. When binding energy (¦¤E or ¦¤G) decreases, in cation-¦Ð complexes, reaction rate k increases. This study has applications in computing rate of the reactions and in thermodn. properties of chem. reactions.

Materials Today: Proceedings published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, COA of Formula: C24H12.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Aberg, Borje published the artcilePlant growth regulators. XII. Monosubstituted phenoxyacetic acids, COA of Formula: C12H16O3, the publication is Kgl. Lantbruks-H?gskol. Ann. (1957), 375-92, database is CAplus.

cf. C.A. 49, 10443h. Tests of the effect on growth were made on flax seedling roots, wheat seedling roots, and oat coleoptile cylinders as previously described (cf. ?berg, Chemistry and Mode of Action of Plant Growth Substances, London, 1956, pp. 93-116). The results were not consistent in some cases. Initial inhibition that could be relieved by indoleacetic acid (IAA) was shown by 2-substituted phenoxyacetic acids at low concentrations and stimulation of the oat cylinders at high concentrations High IAA-like activity by 2-Me- and 2-iso-Pr-compounds contrasted with low of 2-methoxy and 2-NO₂-compounds Low concentrations of 3-Cl-, 3-Br-, 3-Me-, 3-MeO- and 3-NO₂-compounds stimulated growth of wheat roots. Growth of flax roots was inhibited, which could be relieved by ¦Á-(1-naphthylmethylthio)propionic acid. The IAA-like effect of the 4-substituted compounds grew less with increasing size of the substituent. Auxin effects may be caused at high concentrations by the same substance that causes antiauxin effects at low concentration

Kgl. Lantbruks-H?gskol. Ann. published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, COA of Formula: C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Aberg, Borje published the artcilePlant-growth regulators. IX. p-Alkylphenoxyacetic and -propionic acids, and some related derivatives of naturally occurring phenols, Recommanded Product: 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Physiologia Plantarum (1954), 241-52, database is CAplus.

cf. C.A. 48, 5937a; 49, 10443h. The following compounds were studied to determine their auxin or antiauxin activity in the flax root test: (4-methylphenoxy)acetic acid (I); 2-(4-methylphenoxy)propionic acid (II); (4-ethylphenoxy)acetic acid (III); 2-(4-ethylphenoxy)propionic acid (IV); (4-isopropylphenoxy)acetic acid (V); 2-(4-isopropylphenoxy)propionic acid (VI); (4-tert-butylphenoxy)acetic acid (VII); 2-(4-tert-butylphenoxy)propionic acid (VIII); carvacroxyacetic acid (IX); thymoxyacetic acid (X); (4-chlorothymoxy)acetic acid (XI); eugenoxyacetic acid (XII); and isoeugenoxyacetic acid (XIII). Phenoxyacetic acid is antiauxinic but the introduction of the 4-Me group in I imparts some auxin activity which then diminishes with increasing size of the 4-alkyl substituent in III, V, and VII. A similar effect is observed with the series II, IV, VI, and VIII but these must be resolved into their respective enantiomorphs before a clear analysis is possible. XII and XIII also show conspicuous antiauxin activity, probably due to the bulky 4-alkyl substituents. IX is of intermediate activity, while the isomeric X shows only antiauxin activity which is greatly increased in XI by introduction of the Cl atom in the 4-position. This parallels the similar difference to be found between the 2,6-dichloro- and 2,4,6-trichlorophenoxyacetic acids.

Physiologia Plantarum published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Recommanded Product: 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

?Berg, Boerje published the artcileStudies on Plant Growth Regulators. IX. Para-alkyl-phenoxy-acetic and -propionic Acids, and Some Related Derivatives of Naturally Occurring Phenols, Safety of 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Physiologia Plantarum (2006), 7(2), 241-252, database is CAplus.

This article discussed about application of plant growth regulators in flax roots and seedlings as well as effects of para-alkyl phenoxy acetic acids and para-alky-phenoxy propionic acids derived from naturally occurring phenols and some chloro-phenoxy acetic acids. Plant growth regulators including auxins improved roots and seedlings of flax plants whereas plant growth was inhibited by application of 2,4-D.

Physiologia Plantarum published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Safety of 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Aaberg, Boerje published the artcilePlant growth regulators. XL. Some halogeno- and alkyl-phenoxyacetic and optically active -phenoxypropionic acids, COA of Formula: C12H16O3, the publication is Swedish Journal of Agricultural Research (1980), 10(3), 107-14, database is CAplus.

Optically active 4-fluoro- [405-79-8], 3-tert-butyl- [1878-55-3], and 4-tert-butylphenoxypropionic acid [6941-12-4], 2-bromo-4-chloro- [77228-66-1], 4-bromo-2-chloro- [77228-67-2], and 2,4-diiodophenoxyacetic acid [77228-65-0], 4-chloro-2-methylphenoxythioacetic acid [22716-96-7], 4-methyl-2-tert-butyl- [25141-22-4], 2-methyl-5-isopropyl- [19728-20-2], and 5-methyl-2-isopropylphenoxyacetic acid [5333-40-4] have been studied with respect to their growth effect on oat coleoptile cylinders, wheat and flax roots, and have been compared with related substances. There are increases in auxin activity from the acetic to the D(+)-propionic acids, and the L(-)-propionic acids are antiauxinic. The effects of the disubstituted phenoxyacetic acids are in agreement with those expected from a comparison with the corresponding monosubstituted acids. A change from a carboxyl to a thiocarboxyl group has only slight effect on the growth activity.

Swedish Journal of Agricultural Research published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, COA of Formula: C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Talvik, A. published the artcileThe inductive effect. III. The kinetics of the reaction of substituted benzoic acids with diphenyldiazomethane, Synthetic Route of 31719-76-3, the publication is Collection of Czechoslovak Chemical Communications (1964), 29(5), 1266-76, database is CAplus.

cf. CA 59, 9765h. The rate constants of the reaction of diphenyldiazomethane (I) with 19 derivatives of BzOH substituted in the m- and p-position were measured at 25¡ã. The substituents were groups of negligible mesomeric effect. The kinetics were followed by measurement of the polarographic wave height of I in 40% EtOH in the presence of 0.1M NaCl and an excess of BzOH derivative partially titrated with NaOH. The rate constants were in the range 0.28-0.83 l./mole sec.; the dependence of their logarithms on Hammett substituent coasts. is linear. The purely inductive effect is transmitted from the p-position of the C₆H₆ nucleus with a greater intensity than from the m-position; this result is in accord with findings of the preceding part of this series based on measurement of dissociation constants A table of rate constants is given. 32 references.

Collection of Czechoslovak Chemical Communications published new progress about 31719-76-3. 31719-76-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 4-(Phenoxymethyl)benzoic acid, and the molecular formula is C11H16BNO3, Synthetic Route of 31719-76-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dandu, Reddeppareddy published the artcileDesign and synthesis of dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole oximes as potent dual inhibitors of TIE-2 and VEGF-R2 receptor tyrosine kinases, Recommanded Product: O-Isobutylhydroxylamine hydrochloride, the publication is Bioorganic & Medicinal Chemistry Letters (2008), 18(6), 1916-1921, database is CAplus and MEDLINE.

Fused dihydroindazolopyrrolocarbazole oximes have been identified as low nanomolar, potent dual TIE-2 and VEGF-R2 receptor tyrosine kinase inhibitors with excellent cellular potency. Development of the structure-activity relationships (SAR) led to identification of compounds I and II as potent, selective dual TIE-2/VEGF-R2 inhibitors with favorable pharmacokinetic properties. Compound I was orally active in tumor models with no observed toxicity.

Bioorganic & Medicinal Chemistry Letters published new progress about 6084-58-8. 6084-58-8 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is O-Isobutylhydroxylamine hydrochloride, and the molecular formula is C4H12ClNO, Recommanded Product: O-Isobutylhydroxylamine hydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Othmer, Donald F. published the artcileCorrelation of latent heats and entropies of vaporization with temperature, Safety of Difluorodiphenylsilane, the publication is Industrial and Engineering Chemistry (1959), 791-96,1022, database is CAplus.

The latent heat of a substance can be determined by the equation l = [m’l'(1.003 – 0.66 P_r^0.74)]/(1.003 – 0.66 P_r^0.74), where l and l’ are latent heats, P_r and P_r‘ are reduced pressures, and m and m’ are constants, for unknown substance and reference substance. Values of m for more than 500 substances are given. Nomograms for the determination of latent heat and entropy of vaporization with illustrative examples for using them are given. The compounds included hydrocarbons, halogenated hydrocarbons, alcs., and polyols; aldehydes, ketones, ethers, acids, esters, N compounds, phenols, metallo?rg. compounds, B compounds, and Si compounds

Industrial and Engineering Chemistry published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Safety of Difluorodiphenylsilane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Pei, Chunzhe published the artcileNi-Catalyzed Direct Carboxylation of Aryl C-H Bonds in Benzamides with CO₂, Name: 2-Methylbenzoic acid, the publication is Advanced Synthesis & Catalysis (2022), 364(3), 493-499, database is CAplus.

The direct carboxylation of inert aryl C-H bond catalyzed by abundant and cheap nickel is still facing challenge. Herein, authors report the Ni-catalyzed direct carboxylation of aryl C-H bonds in benzamides under 1 atm of CO₂ to afford various Me carboxylates or phthalimides, dealing with different post-processing. The reaction displays excellent functional group tolerance and affords moderate to high carboxylation yields under mild conditions. Detail mechanistic studies suggest that a Ni(0)-Ni(II)-Ni(I) catalytic cycle may be involved in this reaction.

Advanced Synthesis & Catalysis published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Name: 2-Methylbenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia