Catalysis-chemistry

Podyunin, A. A. published the artcileSynthesis and evaluation of antiradiation activity of N-derivatives of guanidinoethanethiols in experiments with yeast cells of Saccharomyces cerevisiae, SDS of cas: 6972-05-0, the publication is Khimiko-Farmatsevticheskii Zhurnal (1990), 24(10), 44-6, database is CAplus.

The title compounds, R¹R²NC(R³HN)NHCH₂CHR⁴SH [I; R¹ = H, Me, Et, CH₂CO₂Na, hydroxy alkyl; R², R³, R⁴ = H, Me; or R²R³ = CH₂] were prepared from R¹R²N(R³NH)CS and BrCHR⁴CH₂NH₂.HBr in 1 step and isolated as trithiocarbonates in 16-46% yield. Compounds (I) were screened for toxicity and radioprotective activity. Derivatives (I; R¹ = Et; R² = R³ = R⁴ = H and R³ = Et; R² = R⁴ = H) showed radioprotective activity in yeast cells.

Khimiko-Farmatsevticheskii Zhurnal published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, SDS of cas: 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zlatopolskiy, Boris D. published the artcileDiscovery of 7-[¹⁸F]Fluorotryptophan as a Novel Positron Emission Tomography (PET) Probe for the Visualization of Tryptophan Metabolism in Vivo, Quality Control of 17351-61-0, the publication is Journal of Medicinal Chemistry (2018), 61(1), 189-206, database is CAplus and MEDLINE.

Tryptophan and its metabolites are involved in different physiol. and pathophysiol. processes. Consequently, positron emission tomog. (PET) tracers addressing tryptophan metabolic pathways should allow the detection of different pathologies like neurol. disorders and cancer. Herein we report an efficient method for the preparation of fluorotryptophans labeled in different positions with ¹⁸F and their biol. evaluation. 4-7-[¹⁸F]Fluorotryptophans ([¹⁸F]FTrps) were prepared according to a modified protocol of alc.-enhanced Cu-mediated radiofluorination in 30-53% radiochem. yields. In vitro experiments demonstrated high cellular uptake of 4-7-[¹⁸F]FTrps in different tumor cell lines. 4, 5-, And 6-[¹⁸F]FTrps, although stable in vitro, suffered from rapid in vivo defluorination. In contrast, 7-[¹⁸F]FTrp demonstrated a high in vivo stability and enabled a clear delineation of serotonergic areas and melatonin-producing pineal gland in rat brains. Moreover 7-[¹⁸F]FTrp accumulated in different tumor xenografts in a chick embryo CAM model. Thus, 7-[¹⁸F]FTrp represents a highly promising PET probe for imaging of Trp metabolism

Journal of Medicinal Chemistry published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C6H13I, Quality Control of 17351-61-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Barkov, Alexey Yu. published the artcileHighly regio- and stereoselective 1,3-dipolar cycloaddition of stabilised azomethine ylides to 3,3,3-trihalogeno-1-nitropropenes: synthesis of trihalomethylated spiro[indoline-3,2′-pyrrolidin]-2-ones and spiro[indoline-3,3′-pyrrolizin]-2-ones, COA of Formula: C10H11NO4, the publication is Tetrahedron (2016), 72(43), 6825-6836, database is CAplus.

Reactions of 3,3,3-trihalogen-1-nitropropenes with N-alkyl-¦Á-amino acids (sarcosine, proline) and isatins proceed regio- and diastereoselectively to give a wide range of trihalomethylated spiro[indoline-3,2′-pyrrolidin]-2-ones I (R¹ = H, 5,7-(Br)₂; R = H, CH₃, C₅H₁₁, Bn; X = F, Br, Cl) and spiro[indoline-3,3′-pyrrolizin]-2-ones II (R¹ = H, 5-NO₂, 5,7-(Br)₂; R = H, CH₃, C₅H₁₁, Bn; X = F, Br, Cl) in good yields as a result of a 1,3-dipolar cycloaddition of the intermediate stabilized azomethine ylide at the double bond of the nitroalkenes.

Tetrahedron published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, COA of Formula: C10H11NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kaminska, Katarzyna published the artcile(2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H₄ receptor ligands, COA of Formula: C9H7NO4, the publication is European Journal of Medicinal Chemistry (2015), 238-251, database is CAplus and MEDLINE.

Within the constantly growing number of histamine H₄ (H₄R) receptor ligands there is a large group of azine derivatives A series of novel compounds in the group of 4-methylpiperazinyl-1,3,5-triazin-2-amines were designed and obtained. Structures were modified at the triazine 6-position by introduction of variously substituted arylethenyl moieties. Their affinities to histamine H₄ receptors were evaluated in radioligand binding assays with use of Sf9 cells, transiently expressing human H₄R. Pharmacol. studies identified 4-[(E)-2-(3-chlorophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine (K_i = 253 nM) as the most potent compound in the present series.

European Journal of Medicinal Chemistry published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C9H7NO4, COA of Formula: C9H7NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xie, Qiqiang published the artcileControllable double CF₂-insertion into sp² C-Cu bond using TMSCF₃: a facile access to tetrafluoroethylene-bridged structures, Formula: C9H9F5Si, the publication is Chemical Science (2020), 11(1), 276-280, database is CAplus and MEDLINE.

A highly efficient method for controllable double CF2-insertion into pentafluorophenylcopper species using TMSCF₃ as difluoromethylene source had been developed. The newly generated fluoroalkylcopper(I) species, C₆F₅CF₂CF₃Cu, showed good reactivity toward a myriad of structurally diverse aryl, heteroaryl and alkenyl iodides. This protocol was easy to handle, ready to scale up and applicable for the synthesis of relative complex mols., thus providing a convenient method for facile access to tetrafluoroethylene-bridged structures C₆F₅CF₂CF₂R [R = 2-thienyl, Ph, 4-NCC₆H₄, etc.].

Chemical Science published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C26H26N4O7, Formula: C9H9F5Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhou, Mi published the artcileBreed dependent regulatory mechanisms of beneficial and non-beneficial fatty acid profiles in subcutaneous adipose tissue in cattle with divergent feed efficiency, HPLC of Formula: 6217-54-5, the publication is Scientific Reports (2022), 12(1), 4612, database is CAplus and MEDLINE.

The current study aimed to determine whether breed and feed efficiency affect the mol. mechanisms regulating beneficial and non-beneficial fatty acid profiles in s.c. adipose tissue of beef steers. Fatty acid profiling and RNA-Seq based transcriptome anal. were performed on s.c. adipose tissues collected from beef steers with three divergent breeds (Angus, ANG, n = 47; Charolais, CHAR, n = 48; Kinsella Composite, KC, n = 48) and different residual feed intake (RFI, a measure of feed efficiency). The comparison of fatty acid profiles showed that KC had higher beneficial FAs compared to the other two breeds. Distinct FA profiles between H-RFIfat and L-RFIfat steers was more obvious for KC steers, where H-RFIfat steers tended to have higher proportion of healthy FAs and lower proportion of the unhealthy FAs. A higher number of differentially expressed (DE) genes were observed for KC steers, whereas ANG and CHAR steers had a lower number of DE genes between H- and L-RFIfat steers. The association analyses of the gene expressions and FA profiles showed that 10 FA metabolism-associated genes together with the one upstream regulator (SREBF1) were associated with the proportion of C18:2n-6, total n-6, PUFA and PUFA/SFA for KC steers but not the other two breeds. S.c. adipose tissue FA profiles and healthy FA index differed in cattle with divergent feed efficiency and such variation was unique for the three examined cattle breeds. Key FA metabolism-associated genes together with SREBF1 which is the upstream regulator of a set of genes involved in lipid metabolism may be of importance for genetic selection of meat with higher healthy FA index in beef cattle.

Scientific Reports published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C10H10CoF6P, HPLC of Formula: 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhao, Lei published the artcileLigand-Controlled NiH-Catalyzed Regiodivergent Chain-Walking Hydroalkylation of Alkenes, Computed Properties of 118-90-1, the publication is Angewandte Chemie, International Edition (2022), 61(30), e202204716, database is CAplus and MEDLINE.

A NiH-catalyzed migratory hydroalkylation of alkenyl amines with predictable and switchable regioselectivity is reported. By utilizing a ligand-controlled, directing group-assisted strategy, various alkyl units are site-selectively installed at inert sp³ C-H sites far away from the original C=C bonds. A range of structurally diverse ¦Á- and ¦Â-branched protected amines are conveniently synthesized via stabilization of 5- and 6-membered nickelacycles resp. This method exhibits broad scope and high functional group tolerance, and can be applied to late-stage modification of medicinally relevant mols.

Angewandte Chemie, International Edition published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C9H4F6O, Computed Properties of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chen, Long published the artcileDirect C-OH/P(O)-H dehydration coupling forming phosphine oxides, Product Details of C18H23OP, the publication is Organic & Biomolecular Chemistry (2018), 16(28), 5090-5093, database is CAplus and MEDLINE.

A t-BuONa-mediated C-OH/P(O)-H cross dehydration coupling to produce alkylphosphine oxides is developed. This reaction employed readily available alcs. and P(O)-H compounds as the starting materials, providing an efficient alternative method for constructing sp³ C-P bonds. A reasonable reaction path involving dehydration and subsequent regio-selective hydrophosphorylation of the resulting alkenes was proposed.

Organic & Biomolecular Chemistry published new progress about 23897-16-7. 23897-16-7 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Dimesitylphosphine oxide, and the molecular formula is C18H23OP, Product Details of C18H23OP.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bartlett, Mairead E. published the artcileCu-Catalyzed Phenol O-Methylation with Methylboronic Acid, Quality Control of 17351-61-0, the publication is European Journal of Organic Chemistry (2021), 2021(41), 5661-5664, database is CAplus.

A Cu-catalyzed oxidative cross-coupling of phenols with methylboronic acid to form aryl Me ethers has been developed, expanding the scope of Chan-Evans-Lam alkylation. Electron-deficient phenol derivatives with a broad array of functional groups are methylated in high yields. Increased reaction temperature and catalyst loading enables the methylation of substrates incorporating pyridine and dihydroquinolone motifs. Electron-rich phenol derivatives are poor substrates for the methylation; the characterization of C-H homodimerization products formed from these substrates illuminates a competing mechanistic pathway.

European Journal of Organic Chemistry published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C9H21NO3, Quality Control of 17351-61-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Yiming published the artcileDirect sulfhydryl ligand derived UiO-66 for removal of aqueous mercury and its subsequent application as catalyst for transfer vinylation, COA of Formula: C8H8O2, the publication is Dalton Transactions (2022), 51(10), 4043-4051, database is CAplus and MEDLINE.

The treatment of mercury pollutants in water has been wide concern. Adsorption is a promising method for mercury removal that has been extensively studied. Nevertheless, the secondary application of the immobilized Hg is seldom investigated. In this paper, the Hg adsorption behavior of UiO-66 bearing sulfhydryl groups is studied. The research shows that the porous structure and sulfhydryl groups of UiO-66-SH can effectively promote the removal of mercury from water. In addition, this work also pushes forward the sequential application of the recovered adsorbent, which contains the adsorbed mercury that may cause secondary pollution. The recovered waste adsorbent, UiO-66-S-Hg, was successfully used as an efficient catalyst for transfer vinylation, which produces value-added products, vinyl benzoates. Eight vinyl esters have been successfully synthesized with a yield of up to 89%. This methodol. provides a promising way for not only the treatment of mercury contamination, but also secondary pollution protection and the resource utilization of immobilized Hg.

Dalton Transactions published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C17H18N3NaO3S, COA of Formula: C8H8O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia