Catalysis-chemistry

Ihara, Masataka published the artcileHighly stereocontrolled synthesis of (¡À)-3-oxosilphinene via intramolecular Diels-Alder reaction, Name: Allyldiphenylphosphine oxide, the publication is Journal of the Chemical Society, Chemical Communications (1986), 671-2, database is CAplus.

The triquinane (¡À)-3-oxosilphinene (I), previously isolated from Dugaldia?hoopesii, was prepared in 18 steps from 3-bromo-2-methylcyclopent-2-enone. The key step was the intramol. Diels-Alder reaction of the diene II in o-C₆H₄Cl₂ at 200-220¡ã for 15 h to give 76% tricyclododecene III.

Journal of the Chemical Society, Chemical Communications published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Name: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ihara, Masataka published the artcileStereoselective total synthesis of (¡À)-3-oxosilphinene through intramolecular Diels-Alder reaction, Name: Allyldiphenylphosphine oxide, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1987), 1331-7, database is CAplus.

The angular tricyclopentanoid sesquiterpene (¡À)-3-oxosilphinene (I) was stereoselectively prepared with an intramol. Diels-Alder reaction as the key step. On heating, the (E,E)-sulfenyltriene II (R = CHMeCH₂CH₂CH:CHCH:CHSPh), derived from II (R = Br) gave only 1 stereoisomer of tricyclo[7.3.0.0^1.5]dodecene III having all 4 contiguous asym. centers with the required stereochem. The cycloadduct III was converted into the racemate of I via ring contraction.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Name: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rius, A. G. published the artcilePhysiological responses of Holstein calves to heat stress and dietary supplementation with a postbiotic from Aspergillus oryzae, Product Details of C5H11NO2S, the publication is Scientific Reports (2022), 12(1), 1587, database is CAplus and MEDLINE.

Increased ambient temperature causes heat stress in mammals, which affects physiol. and mol. functions. We have recently reported that the dietary administration of a postbiotic from Aspergillus oryzae (AO) improves tolerance to heat stress in fruit flies and cattle. Furthermore, heat-induced gut dysfunction and systemic inflammation have been ameliorated in part by nutritional interventions. The objective of this study was to characterize the phenotypic response of growing calves to heat stress compared to thermoneutral ad libitum fed and thermoneutral feed-restricted counterparts and examining the physiol. alterations associated with the administration of the AO postbiotic to heat-stressed calves with emphasis on intestinal permeability. In this report, we expand previous work by first demonstrating that heat stress reduced partial energetic efficiency of growth in control (45%) but not in AO-fed calves (62%) compared to thermoneutral animals (66%). While heat stress increased 20% the permeability of the intestine, AO postbiotic and thermoneutral treatments did not affect this variable. In addition, AO postbiotic reduced fecal water content relative to thermoneutral and heat stress treatments. Heat stress increased plasma concentrations of serum amyloid A, haptoglobin and lipocalin-2, and administration of AO postbiotic did not ameliorate this effect. In summary, our findings indicated that heat stress led to reduced nutrient-use efficiency and increased systemic inflammation. Results suggest that the AO postbiotic improved energy-use efficiency, water absorption, and the intestinal permeability in heat stress-mediated increase in gut permeability but did not reduce heat stress-mediated rise in markers of systemic inflammation.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Product Details of C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tomita, Hiroya published the artcileRapid evaluation of the substrate specificity of 3-nitrobenzoic acid dioxygenase MnbAB via colorimetric detection using Saltzman reagent, COA of Formula: C8H7NO4, the publication is Journal of Industrial Microbiology & Biotechnology (2021), 48(9-10), kuab064, database is CAplus and MEDLINE.

Nitroarom. compounds are essential materials for chem. industry, but they are also potentially toxic environmental pollutants. Therefore, their sensitive detection and degradation are important concerns. The microbial degradation pathways of nitroarom. compounds have been studied in detail, but their usefulness needs to be evaluated to understand their potential applications in bioremediation. Here, we developed a rapid and relatively sensitive assay system to evaluate the activities and substrate specificities of nitroarom. dioxygenases involved in the oxidative biodegradation of nitroarom. compounds In this system, nitrous acid, which was released from the nitroarom. compounds by the dioxygenases, was detected and quantified using the Saltzman reagent. Escherichia coli producing the 3-nitrobenzoic acid dioxygenase complex MnbAB from Comamonas sp. JS46 clearly showed the apparent substrate specificity of MnbAB as follows. MnbAB accepted not only 3-nitrobenzoic acid but also several other p- and m-nitrobenzoic acid derivatives as substrates, although it much preferred 3-nitrobenzoic acid to others. Furthermore, the presence of a hydroxy or an amino group at the ortho position of the nitro group decreased the activity of MnbAB. In addition, MnbAB accepted 2-(4-nitrophenyl)acetic acid as a substrate, which has one addnl. methylene group between the aromatic ring and the carboxy group of 3-nitrobenzoic acid. This is the first report about the detailed substrate specificity of MnbAB. Our system can be used for other nitroarom. dioxygenases and contribute to their characterization.

Journal of Industrial Microbiology & Biotechnology published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C7H9BO3S, COA of Formula: C8H7NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kavetsou, Eleni published the artcileNovel 3-aryl-5-substituted-coumarin analogues: Synthesis and bioactivity profile, Related Products of catalysis-chemistry, the publication is Drug Development Research (2020), 81(4), 456-469, database is CAplus and MEDLINE.

Eighteen 3-phenyl-5-substituted-coumarins, among them six were 5-acetyloxy-derivatives, six 5-hydroxy-derivatives and six 5-geranyloxy-derivatives I [R = hydroxy, acetoxy, geranyloxy; R¹ = H, MeO, Br; R² = H, MeO, Br, O₂N, etc.] were synthesized, structurally characterized and their antioxidant activity, lipoxygenase inhibitory ability, as well as their cytotoxic activity against human neuroblastoma SK-N-SH and HeLa adenocarcinoma cell lines were evaluated. The compounds I [R = hydroxy, acetoxy, geranyloxy; R¹ = H, MeO, Br; R² = H, MeO, Br, O₂N, etc.] were found to be the best cytotoxic agents among all the compounds studied. The bromo-substituted coumarins I [R = acetoxy, R¹ = H, R² = Br; R = acetoxy, R¹ = Br, R² = H] were remarkably active against HeLa cell line showing IC₅₀ 1.8 and 6.1¦ÌM, resp. Coumarin I [R = geranyloxy, R¹ = MeO, R² = H] presented dual bioactivity, while compound I [R = geranyloxy, R¹ = H, R² = MeO] was the most competent soybean lipoxygenase inhibitor of this series (IC₅₀ 10¦ÌM). As shown by in-silico docking studies, the studied mols. present allosteric interactions with soybean lipoxygenases.

Drug Development Research published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C8H7NO4, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Benbow, John W. published the artcileAn efficient route to functionalized dienes for decalin synthesis, Formula: C15H15OP, the publication is Tetrahedron Letters (1997), 38(23), 4017-4020, database is CAplus.

Reaction of the trimethylsilyl (TMS) enol ethers, e.g. I, derived from the conjugate addition of organo-copper reagents to 3,4-dimethylcyclopentenone with di-Me dioxirane (DMDO) leads to ¦Á-hydroxy ketones with predominantly the syn-Me orientation. Exposure of these systems to methanolic lead tetraacetate (Pb(OAc)₄) delivers aldehydic esters which are homologated to the desired E-dienes, e.g. II, using Yamamoto’s allylic phosphine oxide reagent.

Tetrahedron Letters published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Formula: C15H15OP.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kumar, Abhishek published the artcileCopper(II)-catalyzed decarboxylative cyclization for accessing biologically relevant 3-(2-furanyl)indoles from 3-cyanoacetyl indoles and cinnamic acids, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Tetrahedron (2020), 76(36), 131433, database is CAplus.

A novel and efficient route for the synthesis of 3-(2-furanyl)indoles I (R¹ = H, Me, Et; R² = H, Me; R³ = 6-Cl, 5-OMe, 5-F, etc.; R⁴ = Ph, 2-BrC₆H₄, 1-naphthyl, etc.) from readily available 3-cyanoacetyl indoles and ¦Á,¦Â-unsaturated carboxylic acids via Cu(II)-catalyzed decarboxylative, intermol. annulation is reported. In this transformation, di-tert-Bu peroxide was used as an external oxidant. This reaction underwent radical addition, decarboxylative processes, and provides a facile regioselective 3-(2-furanyl)indole derivatives in good to excellent yields.

Tetrahedron published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hayashi, Yoshiki published the artcileBiosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis, Formula: C5H11NO2S, the publication is Scientific Reports (2022), 12(1), 5593, database is CAplus and MEDLINE.

Abstract: Tissue aging is a major cause of aging-related disabilities and a shortened life span. Understanding how tissue aging progresses and identifying the factors underlying tissue aging are crucial; however, the mechanism of tissue aging is not fully understood. Here we show that the biosynthesis of S-adenosyl-methionine (SAM), the major cellular donor of Me group for methylation modifications, potently accelerates the aging-related defects during Drosophila oogenesis. An aging-related increase in the SAM-synthetase (Sam-S) levels in the germline leads to an increase in ovarian SAM levels. Sam-S-dependent biosynthesis of SAM controls aging-related defects in oogenesis through two mechanisms, decreasing the ability to maintain germline stem cells and accelerating the improper formation of egg chambers. Aging-related increases in SAM commonly occur in mouse reproductive tissue and the brain. Therefore, our results raise the possibility suggesting that SAM is the factor related to tissue aging beyond the species and tissues.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Formula: C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sadakiyo, Masaaki published the artcileDesign and Synthesis of Hydroxide Ion-Conductive Metal-Organic Frameworks Based on Salt Inclusion, SDS of cas: 17351-62-1, the publication is Journal of the American Chemical Society (2014), 136(5), 1702-1705, database is CAplus and MEDLINE.

The authors demonstrate a metal-organic framework (MOF) design for the inclusion of hydroxide ions. Salt inclusion method was applied to an alk.-stable ZIF-8 (ZIF = zeolitic imidazolate framework) to introduce alkylammonium hydroxides as ionic carriers. Tetrabutylammonium salts are immobilized inside the pores by a hydrophobic interaction between the alkyl groups of the salt and the framework, which significantly increases the hydrophilicity of ZIF-8. Also, ZIF-8 including the salt exhibited a capacity for OH^– ion exchange, implying that freely exchangeable OH^– ions are present in the MOF. ZIF-8 containing OH^– ions showed an ionic conductivity of 2.3 ¡Á 10^-8 S cm^-1 at 25¡ã, which is 4 orders of magnitude higher than that of the blank ZIF-8. This is the first example of an MOF-based hydroxide ion conductor.

Journal of the American Chemical Society published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, SDS of cas: 17351-62-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gurumurthy, R. published the artcileRuthenium(III)-catalyzed oxidation of phenoxyacetic acids by aqueous phenyliodoso acetate, Formula: C12H16O3, the publication is Oxidation Communications (1993), 16(3-4), 351-7, database is CAplus.

The kinetics of oxidation of phenoxyacetic acid and its derivatives (19 compounds) by phenyliodoso acetate has been studied in 60% (volume/volume) aqueous acetic acid. The reaction is first order with respect to both phenoxyacetic acid and phenyliodoso acetate and is catalyzed by hydrogen ions. Catalysis by Ru(III) is observed A Hammett ¦Ñ value of -2.62 at 35¡ã indicates an electron-deficient transition state. The oxidation rates of ortho-substituted compounds have been analyzed by applying Taft’s steric energy parameters. A suitable mechanism has been proposed.

Oxidation Communications published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Formula: C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia