Catalysis-chemistry

Miura, Yozo published the artcileESR studies of N-(arylthio)-tert-butylaminyls. Part VI, Quality Control of 19117-31-8, the publication is Bulletin of the Chemical Society of Japan (1977), 50(7), 1855-7, database is CAplus.

Me3CN•SC6H4R-p (I; R = H, F, Cl, Br, NO2) are easily generated by the photolysis of Me3CNHSC6H4R-p. ESR spectra of I were split into a 1:1:1 triplet by the interaction with the N nucleus, and each peak of the triplet was further split by the ring protons. The radicals are not sensitive to atm. O.

Bulletin of the Chemical Society of Japan published new progress about 19117-31-8. 19117-31-8 belongs to catalysis-chemistry, auxiliary class Oxidant, name is N-(tert-Butyl)-S-phenylthiohydroxylamine, and the molecular formula is C10H15NS, Quality Control of 19117-31-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Arutyunyan, G. L. published the artcileSynthesis and Conversions of Polyhedral Compounds. 32. Synthesis and Antibacterial Activity of Azaadamantane-Containing Azomethine Dihydrochlorides, SDS of cas: 14707-75-6, the publication is Pharmaceutical Chemistry Journal (2018), 52(5), 419-423, database is CAplus.

New azomethines (Schiff bases) containing azaadamantane groups on one side and several biol. active compounds on the other were synthesized. The antibacterial activity of their dihydrochlorides showed that azomethines containing a nitrofuryl group were most active.

Pharmaceutical Chemistry Journal published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, SDS of cas: 14707-75-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Agadzhanyan, Ts. E. published the artcileSynthesis and hypoglycemic activity of N-(arylsulfonyl)-N’-(1,3,5-triazaadamant-7-yl)ureas, Product Details of C7H14N4, the publication is Khimiko-Farmatsevticheskii Zhurnal (1997), 31(1), 17-18, database is CAplus.

The title compounds (I; R = Cl, Me) were prepared by reaction of 7-amino-1,3,5-triazaadamantane with 4-RC₆H₄SO₂NHCOOEt. I (R = Cl) exhibited higher hypoglycemic activity and lower toxicity in mice than I (R = Me).

Khimiko-Farmatsevticheskii Zhurnal published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Product Details of C7H14N4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Raju, Kalaivanan published the artcileSingle Crystal Growth of N-Benzyl-2-methyl-4-nitroaniline by Seeded Czochralski Pulling Technique for NLO and THz Applications, Quality Control of 201157-13-3, the publication is Crystal Research and Technology (2020), 55(4), 1900234, database is CAplus.

Single crystal of N-benzyl-2-methyl-4-nitroaniline (BNA), a potential organic nonlinear optical (NLO) material for terahertz (THz) pulse generation, is grown successfully from diffusion controlled melt environment by Czochralski pulling (Cz) technique and is reported for the first time. A solution grown crystal having habitual morphol. is used as a seed with pre-determined crystal rotations at constant melt temperature of 102°C. Unit cell structure of melt grown BNA is refined using single crystal X-ray diffraction (SCXRD) anal. and is compared with that of the solution grown one. Crystal packing with the dominance of intermol. hydrogen bonding such as C-H…O, N-H-O, and C-H…π is examined using 2D finger print (FP) plot and 3D Hirshfeld surface (HS) anal. The presence of minimal percentage of voids reflects the good stacking of mol. arrangement in the melt grown crystals when compared to the solution grown ones. Crystalline purity is confirmed by powder X-ray diffraction (PXRD) anal. Modes of vibrations of different functional groups present and wide optical transparency of the grown BNA are realized using Fourier-transform IR (FTIR) and UV-visible-near IR (UV-vis-NIR) spectroscopic analyses, resp. Thermal stability and m.p. are confirmed through differential scanning calorimetry (DSC).

Crystal Research and Technology published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C14H14N2O2, Quality Control of 201157-13-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Konteatis, Zenon published the artcileVorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma, Computed Properties of 421-49-8, the publication is ACS Medicinal Chemistry Letters (2020), 11(2), 101-107, database is CAplus and MEDLINE.

Inhibitors of mutant isocitrate dehydrogenase (mIDH) 1 and 2 cancer-associated enzymes prevent the accumulation of the oncometabolite D-2-hydroxyglutarate (2-HG) and are under clin. investigation for the treatment of several cancers harboring an IDH mutation. Herein, we describe the discovery of vorasidenib (AG-881), a potent, oral, brain-penetrant dual inhibitor of both mIDH1 and mIDH2. X-ray cocrystal structures allowed us to characterize the compound binding site, leading to an understanding of the dual mutant inhibition. Furthermore, vorasidenib penetrates the brain of several preclin. species and inhibits 2-HG production in glioma tissue by >97% in an orthotopic glioma mouse model. Vorasidenib represents a novel dual mIDH1/2 inhibitor and is currently in clin. development for the treatment of low-grade mIDH glioma.

ACS Medicinal Chemistry Letters published new progress about 421-49-8. 421-49-8 belongs to catalysis-chemistry, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain, name is 1,1,1-Trifluoropropan-2-amine, and the molecular formula is C3H6F3N, Computed Properties of 421-49-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Karasu, Feyza published the artcileMechanistic Studies of Photoinitiated Free Radical Polymerization Using a Bifunctional Thioxanthone Acetic Acid Derivative as Photoinitiator, HPLC of Formula: 5411-14-3, the publication is Macromolecules (Washington, DC, United States) (2009), 42(19), 7318-7323, database is CAplus.

A bifunctional photoinitiator for free radical polymerization, thioxanthone catechol-O,O’-diacetic acid, was synthesized, characterized, and compared to photoinitiator parameters of the monofunctional analog, 2-(carboxymethoxy)thioxanthone. Photophys. studies such as fluorescence, phosphorescence, and laser flash photolysis in addition to photopolymerizations of Me methacrylate show that the bifunctional photoinitiator is more efficient in polymer generation than the monofunctional derivative These studies suggest that initiator radicals are generated from a π-π* triplet state in an intramol. electron transfer, followed by proton transfer and decarboxylation to generate alkyl radicals, which initiate polymerization The initial electron transfer is faster for the bifunctional photoinitiator than the monofunctional derivative, which is based on laser flash photolysis studies. Because of the relatively fast intramol. radical generation from the triplet state (triplet lifetime = 490 ns), quenching by mol. oxygen is insignificant and polymerization of Me methacrylate proceeds efficiently without deoxygenation. At higher concentrations of initiator (âˆ? mM) intermol. electron transfer competes with intramol. electron transfer. Both processes, inter- and intramol. processes, yield initiating alkyl radicals.

Macromolecules (Washington, DC, United States) published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, HPLC of Formula: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lo, Enlin published the artcilePhysiological insights into enhanced lipid accumulation and temperature tolerance by Tetraselmis suecica ultraviolet mutants, Name: Docosahexaenoic Acid, the publication is Science of the Total Environment (2022), 156361, database is CAplus and MEDLINE.

High outdoor temperatures significantly inhibit the growth and lipid production of the industrially promising marine microalga Tetraselmis suecica, which is viewed as a potential feedstock for high-value bioproducts and biofuels. To overcome this limitation, T. suecica was subjected to UV irradiation to generate mutants capable of being productive at higher temperatures The top two high-lipid mutants UV-25 and UV-31 isolated at 25°C and 31°C, resp., were compared to the wild type (WT) to delineate physiol. alterations and shed light on the mutants increased biomass and lipid productivity. At 25°C, UV-25 and UV-31 exhibited lipid productivity of 36.12 and 31.33 mg/L day, which were 1.4- and 1.2-fold higher than WT, resp. This increase in lipid biosynthesis correlated well with increased carotenoid content in UV-25 (2.2-fold) and UV-31 (3.6-fold), indicating an improved capacity to quench reactive oxygen species. At 31°C, the growth and lipid accumulation of UV-31 remained high, signifying adaptation to higher temperatures This is attributed to a well-coordinated modulation of the mutant’s cellular metabolism through an increase in galactose and phosphatidylglycerol levels, as well as in protein, all of which contributed to its performance at elevated temperatures The study successfully established a UV mutagenesis strategy for producing superior- performing microalgae strains with industrially desired traits, paving the way for future outdoor cultivation deployment.

Science of the Total Environment published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Name: Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Burkhard, Jiri published the artcileReactivity of triformylmethane. Part II. Reactions of triformylmethane with adamantane derivatives containing primary amino group, Safety of 1,3,5-Triazaadamantan-7-amine, the publication is Collection of Czechoslovak Chemical Communications (1992), 57(9), 1947-50, database is CAplus.

Six new compounds, e.g., RNHCH:C(CHO)₂ (R = R¹, R¹CO, R¹NHCO; R¹ = 1-adamantyl) were obtained by condensation of triformylmethane with some aminoadamantane derivatives RNH₂. The study also includes the reaction of 7-amino-1,3,5-triazaadamantane I (R = H) with triformylmethane to give I [R = CH:C(CHO)₂]. S-1-Adamantyl)isothiourea hydrochloride reacted with triformylmethane to give pyrimidine derivative II (R = 1-adamantyl).

Collection of Czechoslovak Chemical Communications published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Safety of 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Harders, H. published the artcileUrinary copper excretion from rats following administration of aliphatic and alicyclic polyamines, Safety of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Arzneimittel-Forschung (1980), 30(2), 254-8, database is CAplus and MEDLINE.

The effect of oral aliphatic and alicyclic tetramines and tetramine analogs (with 2 N-atoms substituted by O) on Cu excretion was compared with that of D-penicillamine in rats. TETA-HCl (3,6-diazaoctan-1,8-diamine-2HCl) [38260-01-4] and BE 6184-HCl (3,7-diazanonan-1,9-diamine-3HCl) [73510-17-5] were the most active substances. However, simultaneous administration of TETA and D-penicillamine did not potentiate the cupriuretic effect. TETA, s.c. administered, was 3-fold more effective than the orally administered drug.

Arzneimittel-Forschung published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Safety of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dilman, Alexander D. published the artcileTrifluoromethylation of N-Benzoylhydrazones, Quality Control of 1206-46-8, the publication is Journal of Organic Chemistry (2008), 73(14), 5643-5646, database is CAplus and MEDLINE.

A method for the nucleophilic trifluoromethylation of N-benzoylhydrazones using Me₃SiCF₃/AcONa leading to hydrazides, e.g., I (R = H, MeO, NO₂), has been described. The C=N bond of the hydrazones is activated by difluoroboron group, which is introduced by means of boron trifluoride and allylsilane.

Journal of Organic Chemistry published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Quality Control of 1206-46-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia